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Index by author

April 01, 2010; Volume 77,Issue 4

A

  1. Acharya, Poulomi

    1. RETRACTION: Hepatic Heme-Regulated Inhibitor (HRI) Eukaryotic Initiation Factor 2α Kinase: A Protagonist of Heme-Mediated Translational Control of CYP2B Enzymes and a Modulator of Basal Endoplasmic Reticulum Stress Tone
      Poulomi Acharya, Jane-Jane Chen and Maria Almira Correia
      Molecular Pharmacology April 2010, 77 (4) 575-592; DOI: https://doi.org/10.1124/mol.109.061259

  2. Akk, Gustav

    1. Site-Specific Fluorescence Reveals Distinct Structural Changes Induced in the Human ρ1 GABA Receptor by Inhibitory Neurosteroids
      Ping Li, Alpa Khatri, John Bracamontes, David S. Weiss, Joe Henry Steinbach and Gustav Akk
      Molecular Pharmacology April 2010, 77 (4) 539-546; DOI: https://doi.org/10.1124/mol.109.062885

  3. Alvarez-Baron, Claudia

    1. Dominant-Negative Regulation of Cell Surface Expression by a Pentapeptide Motif at the Extreme COOH Terminus of an Slo1 Calcium-Activated Potassium Channel Splice Variant
      Yu-Hsin Chiu, Claudia Alvarez-Baron, Eun Young Kim and Stuart E. Dryer
      Molecular Pharmacology April 2010, 77 (4) 497-507; DOI: https://doi.org/10.1124/mol.109.061929

  4. Alvord, W. Gregory

    1. Pharmacological Analysis of Drosophila melanogaster γ-Secretase with Respect to Differential Proteolysis of Notch and APP
      Casper Groth, W. Gregory Alvord, Octavio A. Quiñones and Mark E. Fortini
      Molecular Pharmacology April 2010, 77 (4) 567-574; DOI: https://doi.org/10.1124/mol.109.062471

  5. Anantharam, V.

    1. Environmental Neurotoxic Pesticide Increases Histone Acetylation to Promote Apoptosis in Dopaminergic Neuronal Cells: Relevance to Epigenetic Mechanisms of Neurodegeneration
      C. Song, A. Kanthasamy, V. Anantharam, F. Sun and A. G. Kanthasamy
      Molecular Pharmacology April 2010, 77 (4) 621-632; DOI: https://doi.org/10.1124/mol.109.062174

  6. Ashraf, Tamima

    1. Regulation of Multidrug Resistance Protein 1 by Tumor Necrosis Factor α in Cultured Glial Cells: Involvement of Nuclear Factor-κB and c-Jun N-Terminal Kinase Signaling Pathways
      Patrick T. Ronaldson, Tamima Ashraf and Reina Bendayan
      Molecular Pharmacology April 2010, 77 (4) 644-659; DOI: https://doi.org/10.1124/mol.109.059410

  7. Atanasov, Atanas G.

    1. Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ
      Nanang Fakhrudin, Angela Ladurner, Atanas G. Atanasov, Elke H. Heiss, Lisa Baumgartner, Patrick Markt, Daniela Schuster, Ernst P. Ellmerer, Gerhard Wolber, Judith M. Rollinger, Hermann Stuppner and Verena M. Dirsch
      Molecular Pharmacology April 2010, 77 (4) 559-566; DOI: https://doi.org/10.1124/mol.109.062141

B

  1. Baumgartner, Lisa

    1. Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ
      Nanang Fakhrudin, Angela Ladurner, Atanas G. Atanasov, Elke H. Heiss, Lisa Baumgartner, Patrick Markt, Daniela Schuster, Ernst P. Ellmerer, Gerhard Wolber, Judith M. Rollinger, Hermann Stuppner and Verena M. Dirsch
      Molecular Pharmacology April 2010, 77 (4) 559-566; DOI: https://doi.org/10.1124/mol.109.062141

  2. Beijnen, Jos H.

    1. Hepatic Clearance of Reactive Glucuronide Metabolites of Diclofenac in the Mouse Is Dependent on Multiple ATP-Binding Cassette Efflux Transporters
      Jurjen S. Lagas, Rolf W. Sparidans, Els Wagenaar, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology April 2010, 77 (4) 687-694; DOI: https://doi.org/10.1124/mol.109.062364

  3. Bendayan, Reina

    1. Regulation of Multidrug Resistance Protein 1 by Tumor Necrosis Factor α in Cultured Glial Cells: Involvement of Nuclear Factor-κB and c-Jun N-Terminal Kinase Signaling Pathways
      Patrick T. Ronaldson, Tamima Ashraf and Reina Bendayan
      Molecular Pharmacology April 2010, 77 (4) 644-659; DOI: https://doi.org/10.1124/mol.109.059410

  4. Boulègue, Cyril

    1. Identification of Determinants of Glucose-Dependent Insulinotropic Polypeptide Receptor That Interact with N-Terminal Biologically Active Region of the Natural Ligand
      Tahir Yaqub, Irina G. Tikhonova, Jens Lättig, Remi Magnan, Marie Laval, Chantal Escrieut, Cyril Boulègue, Chandralal Hewage and Daniel Fourmy
      Molecular Pharmacology April 2010, 77 (4) 547-558; DOI: https://doi.org/10.1124/mol.109.060111

  5. Bracamontes, John

    1. Site-Specific Fluorescence Reveals Distinct Structural Changes Induced in the Human ρ1 GABA Receptor by Inhibitory Neurosteroids
      Ping Li, Alpa Khatri, John Bracamontes, David S. Weiss, Joe Henry Steinbach and Gustav Akk
      Molecular Pharmacology April 2010, 77 (4) 539-546; DOI: https://doi.org/10.1124/mol.109.062885

  6. Briddon, S. J.

    1. Antagonist Selective Modulation of Adenosine A1 and A3 Receptor Pharmacology by the Food Dye Brilliant Black BN: Evidence for Allosteric Interactions
      L. T. May, S. J. Briddon and S. J. Hill
      Molecular Pharmacology April 2010, 77 (4) 678-686; DOI: https://doi.org/10.1124/mol.109.063065

  7. Brim, Remy L.

    1. A Thermally Stable Form of Bacterial Cocaine Esterase: A Potential Therapeutic Agent for Treatment of Cocaine Abuse
      Remy L. Brim, Mark R. Nance, Daniel W. Youngstrom, Diwahar Narasimhan, Chang-Guo Zhan, John J. G. Tesmer, Roger K. Sunahara and James H. Woods
      Molecular Pharmacology April 2010, 77 (4) 593-600; DOI: https://doi.org/10.1124/mol.109.060806

  8. Burgman, Maxim

    1. σ1 Receptor Modulation of G-Protein-Coupled Receptor Signaling: Potentiation of Opioid Transduction Independent from Receptor Binding
      Felix J. Kim, Ivanka Kovalyshyn, Maxim Burgman, Claire Neilan, Chih-Cheng Chien and Gavril W. Pasternak
      Molecular Pharmacology April 2010, 77 (4) 695-703; DOI: https://doi.org/10.1124/mol.109.057083

C

  1. Cashman, John R.

    1. Human Carboxylesterase 1 Stereoselectively Binds the Nerve Agent Cyclosarin and Spontaneously Hydrolyzes the Nerve Agent Sarin
      Andrew C. Hemmert, Tamara C. Otto, Monika Wierdl, Carol C. Edwards, Christopher D. Fleming, Mary MacDonald, John R. Cashman, Philip M. Potter, Douglas M. Cerasoli and Matthew R. Redinbo
      Molecular Pharmacology April 2010, 77 (4) 508-516; DOI: https://doi.org/10.1124/mol.109.062356

  2. Cerasoli, Douglas M.

    1. Human Carboxylesterase 1 Stereoselectively Binds the Nerve Agent Cyclosarin and Spontaneously Hydrolyzes the Nerve Agent Sarin
      Andrew C. Hemmert, Tamara C. Otto, Monika Wierdl, Carol C. Edwards, Christopher D. Fleming, Mary MacDonald, John R. Cashman, Philip M. Potter, Douglas M. Cerasoli and Matthew R. Redinbo
      Molecular Pharmacology April 2010, 77 (4) 508-516; DOI: https://doi.org/10.1124/mol.109.062356

  3. Chen, Jane-Jane

    1. RETRACTION: Hepatic Heme-Regulated Inhibitor (HRI) Eukaryotic Initiation Factor 2α Kinase: A Protagonist of Heme-Mediated Translational Control of CYP2B Enzymes and a Modulator of Basal Endoplasmic Reticulum Stress Tone
      Poulomi Acharya, Jane-Jane Chen and Maria Almira Correia
      Molecular Pharmacology April 2010, 77 (4) 575-592; DOI: https://doi.org/10.1124/mol.109.061259

  4. Cheng, Chao-Min

    1. Role of Rad51 Down-Regulation and Extracellular Signal-Regulated Kinases 1 and 2 Inactivation in Emodin and Mitomycin C-Induced Synergistic Cytotoxicity in Human Non–Small-Cell Lung Cancer Cells
      Ying-Jhen Su, Min-Shao Tsai, Ya-Hsun Kuo, Yu-Fan Chiu, Chao-Min Cheng, Szu-Ting Lin and Yun-Wei Lin
      Molecular Pharmacology April 2010, 77 (4) 633-643; DOI: https://doi.org/10.1124/mol.109.061887

  5. Chien, Chih-Cheng

    1. σ1 Receptor Modulation of G-Protein-Coupled Receptor Signaling: Potentiation of Opioid Transduction Independent from Receptor Binding
      Felix J. Kim, Ivanka Kovalyshyn, Maxim Burgman, Claire Neilan, Chih-Cheng Chien and Gavril W. Pasternak
      Molecular Pharmacology April 2010, 77 (4) 695-703; DOI: https://doi.org/10.1124/mol.109.057083

  6. Chiu, Yu-Fan

    1. Role of Rad51 Down-Regulation and Extracellular Signal-Regulated Kinases 1 and 2 Inactivation in Emodin and Mitomycin C-Induced Synergistic Cytotoxicity in Human Non–Small-Cell Lung Cancer Cells
      Ying-Jhen Su, Min-Shao Tsai, Ya-Hsun Kuo, Yu-Fan Chiu, Chao-Min Cheng, Szu-Ting Lin and Yun-Wei Lin
      Molecular Pharmacology April 2010, 77 (4) 633-643; DOI: https://doi.org/10.1124/mol.109.061887

  7. Chiu, Yu-Hsin

    1. Dominant-Negative Regulation of Cell Surface Expression by a Pentapeptide Motif at the Extreme COOH Terminus of an Slo1 Calcium-Activated Potassium Channel Splice Variant
      Yu-Hsin Chiu, Claudia Alvarez-Baron, Eun Young Kim and Stuart E. Dryer
      Molecular Pharmacology April 2010, 77 (4) 497-507; DOI: https://doi.org/10.1124/mol.109.061929

  8. Correia, Maria Almira

    1. RETRACTION: Hepatic Heme-Regulated Inhibitor (HRI) Eukaryotic Initiation Factor 2α Kinase: A Protagonist of Heme-Mediated Translational Control of CYP2B Enzymes and a Modulator of Basal Endoplasmic Reticulum Stress Tone
      Poulomi Acharya, Jane-Jane Chen and Maria Almira Correia
      Molecular Pharmacology April 2010, 77 (4) 575-592; DOI: https://doi.org/10.1124/mol.109.061259

D

  1. Dirsch, Verena M.

    1. Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ
      Nanang Fakhrudin, Angela Ladurner, Atanas G. Atanasov, Elke H. Heiss, Lisa Baumgartner, Patrick Markt, Daniela Schuster, Ernst P. Ellmerer, Gerhard Wolber, Judith M. Rollinger, Hermann Stuppner and Verena M. Dirsch
      Molecular Pharmacology April 2010, 77 (4) 559-566; DOI: https://doi.org/10.1124/mol.109.062141

  2. Dryer, Stuart E.

    1. Dominant-Negative Regulation of Cell Surface Expression by a Pentapeptide Motif at the Extreme COOH Terminus of an Slo1 Calcium-Activated Potassium Channel Splice Variant
      Yu-Hsin Chiu, Claudia Alvarez-Baron, Eun Young Kim and Stuart E. Dryer
      Molecular Pharmacology April 2010, 77 (4) 497-507; DOI: https://doi.org/10.1124/mol.109.061929

E

  1. Earley, Scott

    1. A Dietary Agonist of Transient Receptor Potential Cation Channel V3 Elicits Endothelium-Dependent Vasodilation
      Scott Earley, Albert L. Gonzales and Zarine I. Garcia
      Molecular Pharmacology April 2010, 77 (4) 612-620; DOI: https://doi.org/10.1124/mol.109.060715

  2. Edwards, Carol C.

    1. Human Carboxylesterase 1 Stereoselectively Binds the Nerve Agent Cyclosarin and Spontaneously Hydrolyzes the Nerve Agent Sarin
      Andrew C. Hemmert, Tamara C. Otto, Monika Wierdl, Carol C. Edwards, Christopher D. Fleming, Mary MacDonald, John R. Cashman, Philip M. Potter, Douglas M. Cerasoli and Matthew R. Redinbo
      Molecular Pharmacology April 2010, 77 (4) 508-516; DOI: https://doi.org/10.1124/mol.109.062356

  3. Ellmerer, Ernst P.

    1. Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ
      Nanang Fakhrudin, Angela Ladurner, Atanas G. Atanasov, Elke H. Heiss, Lisa Baumgartner, Patrick Markt, Daniela Schuster, Ernst P. Ellmerer, Gerhard Wolber, Judith M. Rollinger, Hermann Stuppner and Verena M. Dirsch
      Molecular Pharmacology April 2010, 77 (4) 559-566; DOI: https://doi.org/10.1124/mol.109.062141

  4. Escrieut, Chantal

    1. Identification of Determinants of Glucose-Dependent Insulinotropic Polypeptide Receptor That Interact with N-Terminal Biologically Active Region of the Natural Ligand
      Tahir Yaqub, Irina G. Tikhonova, Jens Lättig, Remi Magnan, Marie Laval, Chantal Escrieut, Cyril Boulègue, Chandralal Hewage and Daniel Fourmy
      Molecular Pharmacology April 2010, 77 (4) 547-558; DOI: https://doi.org/10.1124/mol.109.060111

F

  1. Fakhrudin, Nanang

    1. Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ
      Nanang Fakhrudin, Angela Ladurner, Atanas G. Atanasov, Elke H. Heiss, Lisa Baumgartner, Patrick Markt, Daniela Schuster, Ernst P. Ellmerer, Gerhard Wolber, Judith M. Rollinger, Hermann Stuppner and Verena M. Dirsch
      Molecular Pharmacology April 2010, 77 (4) 559-566; DOI: https://doi.org/10.1124/mol.109.062141

  2. Fleming, Christopher D.

    1. Human Carboxylesterase 1 Stereoselectively Binds the Nerve Agent Cyclosarin and Spontaneously Hydrolyzes the Nerve Agent Sarin
      Andrew C. Hemmert, Tamara C. Otto, Monika Wierdl, Carol C. Edwards, Christopher D. Fleming, Mary MacDonald, John R. Cashman, Philip M. Potter, Douglas M. Cerasoli and Matthew R. Redinbo
      Molecular Pharmacology April 2010, 77 (4) 508-516; DOI: https://doi.org/10.1124/mol.109.062356

  3. Fortini, Mark E.

    1. Pharmacological Analysis of Drosophila melanogaster γ-Secretase with Respect to Differential Proteolysis of Notch and APP
      Casper Groth, W. Gregory Alvord, Octavio A. Quiñones and Mark E. Fortini
      Molecular Pharmacology April 2010, 77 (4) 567-574; DOI: https://doi.org/10.1124/mol.109.062471

  4. Fourmy, Daniel

    1. Identification of Determinants of Glucose-Dependent Insulinotropic Polypeptide Receptor That Interact with N-Terminal Biologically Active Region of the Natural Ligand
      Tahir Yaqub, Irina G. Tikhonova, Jens Lättig, Remi Magnan, Marie Laval, Chantal Escrieut, Cyril Boulègue, Chandralal Hewage and Daniel Fourmy
      Molecular Pharmacology April 2010, 77 (4) 547-558; DOI: https://doi.org/10.1124/mol.109.060111

  5. Fujimoto, Michiko

    1. Detergent-Resistant Microdomains Determine the Localization of σ-1 Receptors to the Endoplasmic Reticulum-Mitochondria Junction
      Teruo Hayashi and Michiko Fujimoto
      Molecular Pharmacology April 2010, 77 (4) 517-528; DOI: https://doi.org/10.1124/mol.109.062539

G

  1. Garcia, Zarine I.

    1. A Dietary Agonist of Transient Receptor Potential Cation Channel V3 Elicits Endothelium-Dependent Vasodilation
      Scott Earley, Albert L. Gonzales and Zarine I. Garcia
      Molecular Pharmacology April 2010, 77 (4) 612-620; DOI: https://doi.org/10.1124/mol.109.060715

  2. Gay, Sean C.

    1. Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution
      Sean C. Gay, Manish B. Shah, Jyothi C. Talakad, Keiko Maekawa, Arthur G. Roberts, P. Ross Wilderman, Ling Sun, Jane Y. Yang, Stephanie C. Huelga, Wen-Xu Hong, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology April 2010, 77 (4) 529-538; DOI: https://doi.org/10.1124/mol.109.062570

  3. Goebel, Ulrich

    1. Carbon Monoxide Releasing Molecule-2 Inhibits Pancreatic Stellate Cell Proliferation by Activating p38 Mitogen-Activated Protein Kinase/Heme Oxygenase-1 Signaling
      Christian I. Schwer, Manuel Mutschler, Patrick Stoll, Ulrich Goebel, Matjaz Humar, Alexander Hoetzel and Rene Schmidt
      Molecular Pharmacology April 2010, 77 (4) 660-669; DOI: https://doi.org/10.1124/mol.109.059519

  4. Gonzales, Albert L.

    1. A Dietary Agonist of Transient Receptor Potential Cation Channel V3 Elicits Endothelium-Dependent Vasodilation
      Scott Earley, Albert L. Gonzales and Zarine I. Garcia
      Molecular Pharmacology April 2010, 77 (4) 612-620; DOI: https://doi.org/10.1124/mol.109.060715

  5. Groth, Casper

    1. Pharmacological Analysis of Drosophila melanogaster γ-Secretase with Respect to Differential Proteolysis of Notch and APP
      Casper Groth, W. Gregory Alvord, Octavio A. Quiñones and Mark E. Fortini
      Molecular Pharmacology April 2010, 77 (4) 567-574; DOI: https://doi.org/10.1124/mol.109.062471

H

  1. Halpert, James R.

    1. Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution
      Sean C. Gay, Manish B. Shah, Jyothi C. Talakad, Keiko Maekawa, Arthur G. Roberts, P. Ross Wilderman, Ling Sun, Jane Y. Yang, Stephanie C. Huelga, Wen-Xu Hong, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology April 2010, 77 (4) 529-538; DOI: https://doi.org/10.1124/mol.109.062570

  2. Hasegawa, Takeshi

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  3. Hayashi, Kenji

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  4. Hayashi, Teruo

    1. Detergent-Resistant Microdomains Determine the Localization of σ-1 Receptors to the Endoplasmic Reticulum-Mitochondria Junction
      Teruo Hayashi and Michiko Fujimoto
      Molecular Pharmacology April 2010, 77 (4) 517-528; DOI: https://doi.org/10.1124/mol.109.062539

  5. Heiss, Elke H.

    1. Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ
      Nanang Fakhrudin, Angela Ladurner, Atanas G. Atanasov, Elke H. Heiss, Lisa Baumgartner, Patrick Markt, Daniela Schuster, Ernst P. Ellmerer, Gerhard Wolber, Judith M. Rollinger, Hermann Stuppner and Verena M. Dirsch
      Molecular Pharmacology April 2010, 77 (4) 559-566; DOI: https://doi.org/10.1124/mol.109.062141

  6. Hemmert, Andrew C.

    1. Human Carboxylesterase 1 Stereoselectively Binds the Nerve Agent Cyclosarin and Spontaneously Hydrolyzes the Nerve Agent Sarin
      Andrew C. Hemmert, Tamara C. Otto, Monika Wierdl, Carol C. Edwards, Christopher D. Fleming, Mary MacDonald, John R. Cashman, Philip M. Potter, Douglas M. Cerasoli and Matthew R. Redinbo
      Molecular Pharmacology April 2010, 77 (4) 508-516; DOI: https://doi.org/10.1124/mol.109.062356

  7. Hewage, Chandralal

    1. Identification of Determinants of Glucose-Dependent Insulinotropic Polypeptide Receptor That Interact with N-Terminal Biologically Active Region of the Natural Ligand
      Tahir Yaqub, Irina G. Tikhonova, Jens Lättig, Remi Magnan, Marie Laval, Chantal Escrieut, Cyril Boulègue, Chandralal Hewage and Daniel Fourmy
      Molecular Pharmacology April 2010, 77 (4) 547-558; DOI: https://doi.org/10.1124/mol.109.060111

  8. Hill, S. J.

    1. Antagonist Selective Modulation of Adenosine A1 and A3 Receptor Pharmacology by the Food Dye Brilliant Black BN: Evidence for Allosteric Interactions
      L. T. May, S. J. Briddon and S. J. Hill
      Molecular Pharmacology April 2010, 77 (4) 678-686; DOI: https://doi.org/10.1124/mol.109.063065

  9. Hoetzel, Alexander

    1. Carbon Monoxide Releasing Molecule-2 Inhibits Pancreatic Stellate Cell Proliferation by Activating p38 Mitogen-Activated Protein Kinase/Heme Oxygenase-1 Signaling
      Christian I. Schwer, Manuel Mutschler, Patrick Stoll, Ulrich Goebel, Matjaz Humar, Alexander Hoetzel and Rene Schmidt
      Molecular Pharmacology April 2010, 77 (4) 660-669; DOI: https://doi.org/10.1124/mol.109.059519

  10. Hong, Wen-Xu

    1. Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution
      Sean C. Gay, Manish B. Shah, Jyothi C. Talakad, Keiko Maekawa, Arthur G. Roberts, P. Ross Wilderman, Ling Sun, Jane Y. Yang, Stephanie C. Huelga, Wen-Xu Hong, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology April 2010, 77 (4) 529-538; DOI: https://doi.org/10.1124/mol.109.062570

  11. Huelga, Stephanie C.

    1. Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution
      Sean C. Gay, Manish B. Shah, Jyothi C. Talakad, Keiko Maekawa, Arthur G. Roberts, P. Ross Wilderman, Ling Sun, Jane Y. Yang, Stephanie C. Huelga, Wen-Xu Hong, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology April 2010, 77 (4) 529-538; DOI: https://doi.org/10.1124/mol.109.062570

  12. Humar, Matjaz

    1. Carbon Monoxide Releasing Molecule-2 Inhibits Pancreatic Stellate Cell Proliferation by Activating p38 Mitogen-Activated Protein Kinase/Heme Oxygenase-1 Signaling
      Christian I. Schwer, Manuel Mutschler, Patrick Stoll, Ulrich Goebel, Matjaz Humar, Alexander Hoetzel and Rene Schmidt
      Molecular Pharmacology April 2010, 77 (4) 660-669; DOI: https://doi.org/10.1124/mol.109.059519

K

  1. Kanthasamy, A.

    1. Environmental Neurotoxic Pesticide Increases Histone Acetylation to Promote Apoptosis in Dopaminergic Neuronal Cells: Relevance to Epigenetic Mechanisms of Neurodegeneration
      C. Song, A. Kanthasamy, V. Anantharam, F. Sun and A. G. Kanthasamy
      Molecular Pharmacology April 2010, 77 (4) 621-632; DOI: https://doi.org/10.1124/mol.109.062174

  2. Kanthasamy, A. G.

    1. Environmental Neurotoxic Pesticide Increases Histone Acetylation to Promote Apoptosis in Dopaminergic Neuronal Cells: Relevance to Epigenetic Mechanisms of Neurodegeneration
      C. Song, A. Kanthasamy, V. Anantharam, F. Sun and A. G. Kanthasamy
      Molecular Pharmacology April 2010, 77 (4) 621-632; DOI: https://doi.org/10.1124/mol.109.062174

  3. Katura, Takashi

    1. 15-Deoxy-Δ12,14-Prostaglandin J2 Biphasically Regulates the Proliferation of Mouse Hippocampal Neural Progenitor Cells by Modulating the Redox State
      Takashi Katura, Takahiro Moriya and Norimichi Nakahata
      Molecular Pharmacology April 2010, 77 (4) 601-611; DOI: https://doi.org/10.1124/mol.109.061010

  4. Khatri, Alpa

    1. Site-Specific Fluorescence Reveals Distinct Structural Changes Induced in the Human ρ1 GABA Receptor by Inhibitory Neurosteroids
      Ping Li, Alpa Khatri, John Bracamontes, David S. Weiss, Joe Henry Steinbach and Gustav Akk
      Molecular Pharmacology April 2010, 77 (4) 539-546; DOI: https://doi.org/10.1124/mol.109.062885

  5. Kim, Eun Young

    1. Dominant-Negative Regulation of Cell Surface Expression by a Pentapeptide Motif at the Extreme COOH Terminus of an Slo1 Calcium-Activated Potassium Channel Splice Variant
      Yu-Hsin Chiu, Claudia Alvarez-Baron, Eun Young Kim and Stuart E. Dryer
      Molecular Pharmacology April 2010, 77 (4) 497-507; DOI: https://doi.org/10.1124/mol.109.061929

  6. Kim, Felix J.

    1. σ1 Receptor Modulation of G-Protein-Coupled Receptor Signaling: Potentiation of Opioid Transduction Independent from Receptor Binding
      Felix J. Kim, Ivanka Kovalyshyn, Maxim Burgman, Claire Neilan, Chih-Cheng Chien and Gavril W. Pasternak
      Molecular Pharmacology April 2010, 77 (4) 695-703; DOI: https://doi.org/10.1124/mol.109.057083

  7. Koide, Yuuki

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  8. Konno, Takashi

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  9. Kovalyshyn, Ivanka

    1. σ1 Receptor Modulation of G-Protein-Coupled Receptor Signaling: Potentiation of Opioid Transduction Independent from Receptor Binding
      Felix J. Kim, Ivanka Kovalyshyn, Maxim Burgman, Claire Neilan, Chih-Cheng Chien and Gavril W. Pasternak
      Molecular Pharmacology April 2010, 77 (4) 695-703; DOI: https://doi.org/10.1124/mol.109.057083

  10. Kuo, Ya-Hsun

    1. Role of Rad51 Down-Regulation and Extracellular Signal-Regulated Kinases 1 and 2 Inactivation in Emodin and Mitomycin C-Induced Synergistic Cytotoxicity in Human Non–Small-Cell Lung Cancer Cells
      Ying-Jhen Su, Min-Shao Tsai, Ya-Hsun Kuo, Yu-Fan Chiu, Chao-Min Cheng, Szu-Ting Lin and Yun-Wei Lin
      Molecular Pharmacology April 2010, 77 (4) 633-643; DOI: https://doi.org/10.1124/mol.109.061887

L

  1. Ladurner, Angela

    1. Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ
      Nanang Fakhrudin, Angela Ladurner, Atanas G. Atanasov, Elke H. Heiss, Lisa Baumgartner, Patrick Markt, Daniela Schuster, Ernst P. Ellmerer, Gerhard Wolber, Judith M. Rollinger, Hermann Stuppner and Verena M. Dirsch
      Molecular Pharmacology April 2010, 77 (4) 559-566; DOI: https://doi.org/10.1124/mol.109.062141

  2. Lagas, Jurjen S.

    1. Hepatic Clearance of Reactive Glucuronide Metabolites of Diclofenac in the Mouse Is Dependent on Multiple ATP-Binding Cassette Efflux Transporters
      Jurjen S. Lagas, Rolf W. Sparidans, Els Wagenaar, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology April 2010, 77 (4) 687-694; DOI: https://doi.org/10.1124/mol.109.062364

  3. Lättig, Jens

    1. Identification of Determinants of Glucose-Dependent Insulinotropic Polypeptide Receptor That Interact with N-Terminal Biologically Active Region of the Natural Ligand
      Tahir Yaqub, Irina G. Tikhonova, Jens Lättig, Remi Magnan, Marie Laval, Chantal Escrieut, Cyril Boulègue, Chandralal Hewage and Daniel Fourmy
      Molecular Pharmacology April 2010, 77 (4) 547-558; DOI: https://doi.org/10.1124/mol.109.060111

  4. Laval, Marie

    1. Identification of Determinants of Glucose-Dependent Insulinotropic Polypeptide Receptor That Interact with N-Terminal Biologically Active Region of the Natural Ligand
      Tahir Yaqub, Irina G. Tikhonova, Jens Lättig, Remi Magnan, Marie Laval, Chantal Escrieut, Cyril Boulègue, Chandralal Hewage and Daniel Fourmy
      Molecular Pharmacology April 2010, 77 (4) 547-558; DOI: https://doi.org/10.1124/mol.109.060111

  5. Li, Ping

    1. Site-Specific Fluorescence Reveals Distinct Structural Changes Induced in the Human ρ1 GABA Receptor by Inhibitory Neurosteroids
      Ping Li, Alpa Khatri, John Bracamontes, David S. Weiss, Joe Henry Steinbach and Gustav Akk
      Molecular Pharmacology April 2010, 77 (4) 539-546; DOI: https://doi.org/10.1124/mol.109.062885

  6. Lin, Szu-Ting

    1. Role of Rad51 Down-Regulation and Extracellular Signal-Regulated Kinases 1 and 2 Inactivation in Emodin and Mitomycin C-Induced Synergistic Cytotoxicity in Human Non–Small-Cell Lung Cancer Cells
      Ying-Jhen Su, Min-Shao Tsai, Ya-Hsun Kuo, Yu-Fan Chiu, Chao-Min Cheng, Szu-Ting Lin and Yun-Wei Lin
      Molecular Pharmacology April 2010, 77 (4) 633-643; DOI: https://doi.org/10.1124/mol.109.061887

  7. Lin, Yun-Wei

    1. Role of Rad51 Down-Regulation and Extracellular Signal-Regulated Kinases 1 and 2 Inactivation in Emodin and Mitomycin C-Induced Synergistic Cytotoxicity in Human Non–Small-Cell Lung Cancer Cells
      Ying-Jhen Su, Min-Shao Tsai, Ya-Hsun Kuo, Yu-Fan Chiu, Chao-Min Cheng, Szu-Ting Lin and Yun-Wei Lin
      Molecular Pharmacology April 2010, 77 (4) 633-643; DOI: https://doi.org/10.1124/mol.109.061887

M

  1. MacDonald, Mary

    1. Human Carboxylesterase 1 Stereoselectively Binds the Nerve Agent Cyclosarin and Spontaneously Hydrolyzes the Nerve Agent Sarin
      Andrew C. Hemmert, Tamara C. Otto, Monika Wierdl, Carol C. Edwards, Christopher D. Fleming, Mary MacDonald, John R. Cashman, Philip M. Potter, Douglas M. Cerasoli and Matthew R. Redinbo
      Molecular Pharmacology April 2010, 77 (4) 508-516; DOI: https://doi.org/10.1124/mol.109.062356

  2. Maekawa, Keiko

    1. Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution
      Sean C. Gay, Manish B. Shah, Jyothi C. Talakad, Keiko Maekawa, Arthur G. Roberts, P. Ross Wilderman, Ling Sun, Jane Y. Yang, Stephanie C. Huelga, Wen-Xu Hong, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology April 2010, 77 (4) 529-538; DOI: https://doi.org/10.1124/mol.109.062570

  3. Magnan, Remi

    1. Identification of Determinants of Glucose-Dependent Insulinotropic Polypeptide Receptor That Interact with N-Terminal Biologically Active Region of the Natural Ligand
      Tahir Yaqub, Irina G. Tikhonova, Jens Lättig, Remi Magnan, Marie Laval, Chantal Escrieut, Cyril Boulègue, Chandralal Hewage and Daniel Fourmy
      Molecular Pharmacology April 2010, 77 (4) 547-558; DOI: https://doi.org/10.1124/mol.109.060111

  4. Markt, Patrick

    1. Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ
      Nanang Fakhrudin, Angela Ladurner, Atanas G. Atanasov, Elke H. Heiss, Lisa Baumgartner, Patrick Markt, Daniela Schuster, Ernst P. Ellmerer, Gerhard Wolber, Judith M. Rollinger, Hermann Stuppner and Verena M. Dirsch
      Molecular Pharmacology April 2010, 77 (4) 559-566; DOI: https://doi.org/10.1124/mol.109.062141

  5. May, L. T.

    1. Antagonist Selective Modulation of Adenosine A1 and A3 Receptor Pharmacology by the Food Dye Brilliant Black BN: Evidence for Allosteric Interactions
      L. T. May, S. J. Briddon and S. J. Hill
      Molecular Pharmacology April 2010, 77 (4) 678-686; DOI: https://doi.org/10.1124/mol.109.063065

  6. Mochizuki, Naoki

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  7. Mori, Koji

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  8. Moriya, Takahiro

    1. 15-Deoxy-Δ12,14-Prostaglandin J2 Biphasically Regulates the Proliferation of Mouse Hippocampal Neural Progenitor Cells by Modulating the Redox State
      Takashi Katura, Takahiro Moriya and Norimichi Nakahata
      Molecular Pharmacology April 2010, 77 (4) 601-611; DOI: https://doi.org/10.1124/mol.109.061010

  9. Murakami, Akira

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  10. Mutschler, Manuel

    1. Carbon Monoxide Releasing Molecule-2 Inhibits Pancreatic Stellate Cell Proliferation by Activating p38 Mitogen-Activated Protein Kinase/Heme Oxygenase-1 Signaling
      Christian I. Schwer, Manuel Mutschler, Patrick Stoll, Ulrich Goebel, Matjaz Humar, Alexander Hoetzel and Rene Schmidt
      Molecular Pharmacology April 2010, 77 (4) 660-669; DOI: https://doi.org/10.1124/mol.109.059519

N

  1. Nakahata, Norimichi

    1. 15-Deoxy-Δ12,14-Prostaglandin J2 Biphasically Regulates the Proliferation of Mouse Hippocampal Neural Progenitor Cells by Modulating the Redox State
      Takashi Katura, Takahiro Moriya and Norimichi Nakahata
      Molecular Pharmacology April 2010, 77 (4) 601-611; DOI: https://doi.org/10.1124/mol.109.061010

  2. Nance, Mark R.

    1. A Thermally Stable Form of Bacterial Cocaine Esterase: A Potential Therapeutic Agent for Treatment of Cocaine Abuse
      Remy L. Brim, Mark R. Nance, Daniel W. Youngstrom, Diwahar Narasimhan, Chang-Guo Zhan, John J. G. Tesmer, Roger K. Sunahara and James H. Woods
      Molecular Pharmacology April 2010, 77 (4) 593-600; DOI: https://doi.org/10.1124/mol.109.060806

  3. Narasimhan, Diwahar

    1. A Thermally Stable Form of Bacterial Cocaine Esterase: A Potential Therapeutic Agent for Treatment of Cocaine Abuse
      Remy L. Brim, Mark R. Nance, Daniel W. Youngstrom, Diwahar Narasimhan, Chang-Guo Zhan, John J. G. Tesmer, Roger K. Sunahara and James H. Woods
      Molecular Pharmacology April 2010, 77 (4) 593-600; DOI: https://doi.org/10.1124/mol.109.060806

  4. Neilan, Claire

    1. σ1 Receptor Modulation of G-Protein-Coupled Receptor Signaling: Potentiation of Opioid Transduction Independent from Receptor Binding
      Felix J. Kim, Ivanka Kovalyshyn, Maxim Burgman, Claire Neilan, Chih-Cheng Chien and Gavril W. Pasternak
      Molecular Pharmacology April 2010, 77 (4) 695-703; DOI: https://doi.org/10.1124/mol.109.057083

O

  1. Ohnuma, Shinya

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  2. Otto, Tamara C.

    1. Human Carboxylesterase 1 Stereoselectively Binds the Nerve Agent Cyclosarin and Spontaneously Hydrolyzes the Nerve Agent Sarin
      Andrew C. Hemmert, Tamara C. Otto, Monika Wierdl, Carol C. Edwards, Christopher D. Fleming, Mary MacDonald, John R. Cashman, Philip M. Potter, Douglas M. Cerasoli and Matthew R. Redinbo
      Molecular Pharmacology April 2010, 77 (4) 508-516; DOI: https://doi.org/10.1124/mol.109.062356

P

  1. Pasternak, Gavril W.

    1. σ1 Receptor Modulation of G-Protein-Coupled Receptor Signaling: Potentiation of Opioid Transduction Independent from Receptor Binding
      Felix J. Kim, Ivanka Kovalyshyn, Maxim Burgman, Claire Neilan, Chih-Cheng Chien and Gavril W. Pasternak
      Molecular Pharmacology April 2010, 77 (4) 695-703; DOI: https://doi.org/10.1124/mol.109.057083

  2. Potter, Philip M.

    1. Human Carboxylesterase 1 Stereoselectively Binds the Nerve Agent Cyclosarin and Spontaneously Hydrolyzes the Nerve Agent Sarin
      Andrew C. Hemmert, Tamara C. Otto, Monika Wierdl, Carol C. Edwards, Christopher D. Fleming, Mary MacDonald, John R. Cashman, Philip M. Potter, Douglas M. Cerasoli and Matthew R. Redinbo
      Molecular Pharmacology April 2010, 77 (4) 508-516; DOI: https://doi.org/10.1124/mol.109.062356

Q

  1. Quiñones, Octavio A.

    1. Pharmacological Analysis of Drosophila melanogaster γ-Secretase with Respect to Differential Proteolysis of Notch and APP
      Casper Groth, W. Gregory Alvord, Octavio A. Quiñones and Mark E. Fortini
      Molecular Pharmacology April 2010, 77 (4) 567-574; DOI: https://doi.org/10.1124/mol.109.062471

R

  1. Redinbo, Matthew R.

    1. Human Carboxylesterase 1 Stereoselectively Binds the Nerve Agent Cyclosarin and Spontaneously Hydrolyzes the Nerve Agent Sarin
      Andrew C. Hemmert, Tamara C. Otto, Monika Wierdl, Carol C. Edwards, Christopher D. Fleming, Mary MacDonald, John R. Cashman, Philip M. Potter, Douglas M. Cerasoli and Matthew R. Redinbo
      Molecular Pharmacology April 2010, 77 (4) 508-516; DOI: https://doi.org/10.1124/mol.109.062356

  2. Roberts, Arthur G.

    1. Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution
      Sean C. Gay, Manish B. Shah, Jyothi C. Talakad, Keiko Maekawa, Arthur G. Roberts, P. Ross Wilderman, Ling Sun, Jane Y. Yang, Stephanie C. Huelga, Wen-Xu Hong, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology April 2010, 77 (4) 529-538; DOI: https://doi.org/10.1124/mol.109.062570

  3. Rollinger, Judith M.

    1. Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ
      Nanang Fakhrudin, Angela Ladurner, Atanas G. Atanasov, Elke H. Heiss, Lisa Baumgartner, Patrick Markt, Daniela Schuster, Ernst P. Ellmerer, Gerhard Wolber, Judith M. Rollinger, Hermann Stuppner and Verena M. Dirsch
      Molecular Pharmacology April 2010, 77 (4) 559-566; DOI: https://doi.org/10.1124/mol.109.062141

  4. Ronaldson, Patrick T.

    1. Regulation of Multidrug Resistance Protein 1 by Tumor Necrosis Factor α in Cultured Glial Cells: Involvement of Nuclear Factor-κB and c-Jun N-Terminal Kinase Signaling Pathways
      Patrick T. Ronaldson, Tamima Ashraf and Reina Bendayan
      Molecular Pharmacology April 2010, 77 (4) 644-659; DOI: https://doi.org/10.1124/mol.109.059410

  5. Rybalkin, Sergei D.

    1. Multiple Affinity States of cGMP-Specific Phosphodiesterase for Sildenafil Inhibition Defined by cGMP-Dependent and cGMP-Independent Mechanisms
      Irina G. Rybalkina, Xiao-Bo Tang and Sergei D. Rybalkin
      Molecular Pharmacology April 2010, 77 (4) 670-677; DOI: https://doi.org/10.1124/mol.109.062299

  6. Rybalkina, Irina G.

    1. Multiple Affinity States of cGMP-Specific Phosphodiesterase for Sildenafil Inhibition Defined by cGMP-Dependent and cGMP-Independent Mechanisms
      Irina G. Rybalkina, Xiao-Bo Tang and Sergei D. Rybalkin
      Molecular Pharmacology April 2010, 77 (4) 670-677; DOI: https://doi.org/10.1124/mol.109.062299

S

  1. Sakurai, Atsuko

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  2. Sasamori, Jun

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  3. Sato, Yoshimichi

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  4. Schinkel, Alfred H.

    1. Hepatic Clearance of Reactive Glucuronide Metabolites of Diclofenac in the Mouse Is Dependent on Multiple ATP-Binding Cassette Efflux Transporters
      Jurjen S. Lagas, Rolf W. Sparidans, Els Wagenaar, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology April 2010, 77 (4) 687-694; DOI: https://doi.org/10.1124/mol.109.062364

  5. Schmidt, Rene

    1. Carbon Monoxide Releasing Molecule-2 Inhibits Pancreatic Stellate Cell Proliferation by Activating p38 Mitogen-Activated Protein Kinase/Heme Oxygenase-1 Signaling
      Christian I. Schwer, Manuel Mutschler, Patrick Stoll, Ulrich Goebel, Matjaz Humar, Alexander Hoetzel and Rene Schmidt
      Molecular Pharmacology April 2010, 77 (4) 660-669; DOI: https://doi.org/10.1124/mol.109.059519

  6. Schuster, Daniela

    1. Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ
      Nanang Fakhrudin, Angela Ladurner, Atanas G. Atanasov, Elke H. Heiss, Lisa Baumgartner, Patrick Markt, Daniela Schuster, Ernst P. Ellmerer, Gerhard Wolber, Judith M. Rollinger, Hermann Stuppner and Verena M. Dirsch
      Molecular Pharmacology April 2010, 77 (4) 559-566; DOI: https://doi.org/10.1124/mol.109.062141

  7. Schwer, Christian I.

    1. Carbon Monoxide Releasing Molecule-2 Inhibits Pancreatic Stellate Cell Proliferation by Activating p38 Mitogen-Activated Protein Kinase/Heme Oxygenase-1 Signaling
      Christian I. Schwer, Manuel Mutschler, Patrick Stoll, Ulrich Goebel, Matjaz Humar, Alexander Hoetzel and Rene Schmidt
      Molecular Pharmacology April 2010, 77 (4) 660-669; DOI: https://doi.org/10.1124/mol.109.059519

  8. Shah, Manish B.

    1. Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution
      Sean C. Gay, Manish B. Shah, Jyothi C. Talakad, Keiko Maekawa, Arthur G. Roberts, P. Ross Wilderman, Ling Sun, Jane Y. Yang, Stephanie C. Huelga, Wen-Xu Hong, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology April 2010, 77 (4) 529-538; DOI: https://doi.org/10.1124/mol.109.062570

  9. Song, C.

    1. Environmental Neurotoxic Pesticide Increases Histone Acetylation to Promote Apoptosis in Dopaminergic Neuronal Cells: Relevance to Epigenetic Mechanisms of Neurodegeneration
      C. Song, A. Kanthasamy, V. Anantharam, F. Sun and A. G. Kanthasamy
      Molecular Pharmacology April 2010, 77 (4) 621-632; DOI: https://doi.org/10.1124/mol.109.062174

  10. Sparidans, Rolf W.

    1. Hepatic Clearance of Reactive Glucuronide Metabolites of Diclofenac in the Mouse Is Dependent on Multiple ATP-Binding Cassette Efflux Transporters
      Jurjen S. Lagas, Rolf W. Sparidans, Els Wagenaar, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology April 2010, 77 (4) 687-694; DOI: https://doi.org/10.1124/mol.109.062364

  11. Steinbach, Joe Henry

    1. Site-Specific Fluorescence Reveals Distinct Structural Changes Induced in the Human ρ1 GABA Receptor by Inhibitory Neurosteroids
      Ping Li, Alpa Khatri, John Bracamontes, David S. Weiss, Joe Henry Steinbach and Gustav Akk
      Molecular Pharmacology April 2010, 77 (4) 539-546; DOI: https://doi.org/10.1124/mol.109.062885

  12. Stoll, Patrick

    1. Carbon Monoxide Releasing Molecule-2 Inhibits Pancreatic Stellate Cell Proliferation by Activating p38 Mitogen-Activated Protein Kinase/Heme Oxygenase-1 Signaling
      Christian I. Schwer, Manuel Mutschler, Patrick Stoll, Ulrich Goebel, Matjaz Humar, Alexander Hoetzel and Rene Schmidt
      Molecular Pharmacology April 2010, 77 (4) 660-669; DOI: https://doi.org/10.1124/mol.109.059519

  13. Stout, C. David

    1. Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution
      Sean C. Gay, Manish B. Shah, Jyothi C. Talakad, Keiko Maekawa, Arthur G. Roberts, P. Ross Wilderman, Ling Sun, Jane Y. Yang, Stephanie C. Huelga, Wen-Xu Hong, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology April 2010, 77 (4) 529-538; DOI: https://doi.org/10.1124/mol.109.062570

  14. Stuppner, Hermann

    1. Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ
      Nanang Fakhrudin, Angela Ladurner, Atanas G. Atanasov, Elke H. Heiss, Lisa Baumgartner, Patrick Markt, Daniela Schuster, Ernst P. Ellmerer, Gerhard Wolber, Judith M. Rollinger, Hermann Stuppner and Verena M. Dirsch
      Molecular Pharmacology April 2010, 77 (4) 559-566; DOI: https://doi.org/10.1124/mol.109.062141

  15. Su, Ying-Jhen

    1. Role of Rad51 Down-Regulation and Extracellular Signal-Regulated Kinases 1 and 2 Inactivation in Emodin and Mitomycin C-Induced Synergistic Cytotoxicity in Human Non–Small-Cell Lung Cancer Cells
      Ying-Jhen Su, Min-Shao Tsai, Ya-Hsun Kuo, Yu-Fan Chiu, Chao-Min Cheng, Szu-Ting Lin and Yun-Wei Lin
      Molecular Pharmacology April 2010, 77 (4) 633-643; DOI: https://doi.org/10.1124/mol.109.061887

  16. Sun, F.

    1. Environmental Neurotoxic Pesticide Increases Histone Acetylation to Promote Apoptosis in Dopaminergic Neuronal Cells: Relevance to Epigenetic Mechanisms of Neurodegeneration
      C. Song, A. Kanthasamy, V. Anantharam, F. Sun and A. G. Kanthasamy
      Molecular Pharmacology April 2010, 77 (4) 621-632; DOI: https://doi.org/10.1124/mol.109.062174

  17. Sun, Ling

    1. Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution
      Sean C. Gay, Manish B. Shah, Jyothi C. Talakad, Keiko Maekawa, Arthur G. Roberts, P. Ross Wilderman, Ling Sun, Jane Y. Yang, Stephanie C. Huelga, Wen-Xu Hong, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology April 2010, 77 (4) 529-538; DOI: https://doi.org/10.1124/mol.109.062570

  18. Sunahara, Roger K.

    1. A Thermally Stable Form of Bacterial Cocaine Esterase: A Potential Therapeutic Agent for Treatment of Cocaine Abuse
      Remy L. Brim, Mark R. Nance, Daniel W. Youngstrom, Diwahar Narasimhan, Chang-Guo Zhan, John J. G. Tesmer, Roger K. Sunahara and James H. Woods
      Molecular Pharmacology April 2010, 77 (4) 593-600; DOI: https://doi.org/10.1124/mol.109.060806

T

  1. Takahashi, Atsuo

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  2. Takakura, Nobuyuki

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  3. Takasugi, Hiroshi

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  4. Takeda, Satoshi

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  5. Talakad, Jyothi C.

    1. Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution
      Sean C. Gay, Manish B. Shah, Jyothi C. Talakad, Keiko Maekawa, Arthur G. Roberts, P. Ross Wilderman, Ling Sun, Jane Y. Yang, Stephanie C. Huelga, Wen-Xu Hong, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology April 2010, 77 (4) 529-538; DOI: https://doi.org/10.1124/mol.109.062570

  6. Tang, Xiao-Bo

    1. Multiple Affinity States of cGMP-Specific Phosphodiesterase for Sildenafil Inhibition Defined by cGMP-Dependent and cGMP-Independent Mechanisms
      Irina G. Rybalkina, Xiao-Bo Tang and Sergei D. Rybalkin
      Molecular Pharmacology April 2010, 77 (4) 670-677; DOI: https://doi.org/10.1124/mol.109.062299

  7. Tesmer, John J. G.

    1. A Thermally Stable Form of Bacterial Cocaine Esterase: A Potential Therapeutic Agent for Treatment of Cocaine Abuse
      Remy L. Brim, Mark R. Nance, Daniel W. Youngstrom, Diwahar Narasimhan, Chang-Guo Zhan, John J. G. Tesmer, Roger K. Sunahara and James H. Woods
      Molecular Pharmacology April 2010, 77 (4) 593-600; DOI: https://doi.org/10.1124/mol.109.060806

  8. Tikhonova, Irina G.

    1. Identification of Determinants of Glucose-Dependent Insulinotropic Polypeptide Receptor That Interact with N-Terminal Biologically Active Region of the Natural Ligand
      Tahir Yaqub, Irina G. Tikhonova, Jens Lättig, Remi Magnan, Marie Laval, Chantal Escrieut, Cyril Boulègue, Chandralal Hewage and Daniel Fourmy
      Molecular Pharmacology April 2010, 77 (4) 547-558; DOI: https://doi.org/10.1124/mol.109.060111

  9. Tsai, Min-Shao

    1. Role of Rad51 Down-Regulation and Extracellular Signal-Regulated Kinases 1 and 2 Inactivation in Emodin and Mitomycin C-Induced Synergistic Cytotoxicity in Human Non–Small-Cell Lung Cancer Cells
      Ying-Jhen Su, Min-Shao Tsai, Ya-Hsun Kuo, Yu-Fan Chiu, Chao-Min Cheng, Szu-Ting Lin and Yun-Wei Lin
      Molecular Pharmacology April 2010, 77 (4) 633-643; DOI: https://doi.org/10.1124/mol.109.061887

W

  1. Wagenaar, Els

    1. Hepatic Clearance of Reactive Glucuronide Metabolites of Diclofenac in the Mouse Is Dependent on Multiple ATP-Binding Cassette Efflux Transporters
      Jurjen S. Lagas, Rolf W. Sparidans, Els Wagenaar, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology April 2010, 77 (4) 687-694; DOI: https://doi.org/10.1124/mol.109.062364

  2. Watanabe, Yoshiaki

    1. Sphingosine 1-Phosphate (S1P) Regulates Vascular Contraction via S1P3 Receptor: Investigation Based on a New S1P3 Receptor Antagonist
      Akira Murakami, Hiroshi Takasugi, Shinya Ohnuma, Yuuki Koide, Atsuko Sakurai, Satoshi Takeda, Takeshi Hasegawa, Jun Sasamori, Takashi Konno, Kenji Hayashi, Yoshiaki Watanabe, Koji Mori, Yoshimichi Sato, Atsuo Takahashi, Naoki Mochizuki and Nobuyuki Takakura
      Molecular Pharmacology April 2010, 77 (4) 704-713; DOI: https://doi.org/10.1124/mol.109.061481

  3. Weiss, David S.

    1. Site-Specific Fluorescence Reveals Distinct Structural Changes Induced in the Human ρ1 GABA Receptor by Inhibitory Neurosteroids
      Ping Li, Alpa Khatri, John Bracamontes, David S. Weiss, Joe Henry Steinbach and Gustav Akk
      Molecular Pharmacology April 2010, 77 (4) 539-546; DOI: https://doi.org/10.1124/mol.109.062885

  4. Wierdl, Monika

    1. Human Carboxylesterase 1 Stereoselectively Binds the Nerve Agent Cyclosarin and Spontaneously Hydrolyzes the Nerve Agent Sarin
      Andrew C. Hemmert, Tamara C. Otto, Monika Wierdl, Carol C. Edwards, Christopher D. Fleming, Mary MacDonald, John R. Cashman, Philip M. Potter, Douglas M. Cerasoli and Matthew R. Redinbo
      Molecular Pharmacology April 2010, 77 (4) 508-516; DOI: https://doi.org/10.1124/mol.109.062356

  5. Wilderman, P. Ross

    1. Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution
      Sean C. Gay, Manish B. Shah, Jyothi C. Talakad, Keiko Maekawa, Arthur G. Roberts, P. Ross Wilderman, Ling Sun, Jane Y. Yang, Stephanie C. Huelga, Wen-Xu Hong, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology April 2010, 77 (4) 529-538; DOI: https://doi.org/10.1124/mol.109.062570

  6. Wolber, Gerhard

    1. Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ
      Nanang Fakhrudin, Angela Ladurner, Atanas G. Atanasov, Elke H. Heiss, Lisa Baumgartner, Patrick Markt, Daniela Schuster, Ernst P. Ellmerer, Gerhard Wolber, Judith M. Rollinger, Hermann Stuppner and Verena M. Dirsch
      Molecular Pharmacology April 2010, 77 (4) 559-566; DOI: https://doi.org/10.1124/mol.109.062141

  7. Woods, James H.

    1. A Thermally Stable Form of Bacterial Cocaine Esterase: A Potential Therapeutic Agent for Treatment of Cocaine Abuse
      Remy L. Brim, Mark R. Nance, Daniel W. Youngstrom, Diwahar Narasimhan, Chang-Guo Zhan, John J. G. Tesmer, Roger K. Sunahara and James H. Woods
      Molecular Pharmacology April 2010, 77 (4) 593-600; DOI: https://doi.org/10.1124/mol.109.060806

Y

  1. Yang, Jane Y.

    1. Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution
      Sean C. Gay, Manish B. Shah, Jyothi C. Talakad, Keiko Maekawa, Arthur G. Roberts, P. Ross Wilderman, Ling Sun, Jane Y. Yang, Stephanie C. Huelga, Wen-Xu Hong, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology April 2010, 77 (4) 529-538; DOI: https://doi.org/10.1124/mol.109.062570

  2. Yaqub, Tahir

    1. Identification of Determinants of Glucose-Dependent Insulinotropic Polypeptide Receptor That Interact with N-Terminal Biologically Active Region of the Natural Ligand
      Tahir Yaqub, Irina G. Tikhonova, Jens Lättig, Remi Magnan, Marie Laval, Chantal Escrieut, Cyril Boulègue, Chandralal Hewage and Daniel Fourmy
      Molecular Pharmacology April 2010, 77 (4) 547-558; DOI: https://doi.org/10.1124/mol.109.060111

  3. Youngstrom, Daniel W.

    1. A Thermally Stable Form of Bacterial Cocaine Esterase: A Potential Therapeutic Agent for Treatment of Cocaine Abuse
      Remy L. Brim, Mark R. Nance, Daniel W. Youngstrom, Diwahar Narasimhan, Chang-Guo Zhan, John J. G. Tesmer, Roger K. Sunahara and James H. Woods
      Molecular Pharmacology April 2010, 77 (4) 593-600; DOI: https://doi.org/10.1124/mol.109.060806

Z

  1. Zhan, Chang-Guo

    1. A Thermally Stable Form of Bacterial Cocaine Esterase: A Potential Therapeutic Agent for Treatment of Cocaine Abuse
      Remy L. Brim, Mark R. Nance, Daniel W. Youngstrom, Diwahar Narasimhan, Chang-Guo Zhan, John J. G. Tesmer, Roger K. Sunahara and James H. Woods
      Molecular Pharmacology April 2010, 77 (4) 593-600; DOI: https://doi.org/10.1124/mol.109.060806

  2. Zhang, Qinghai

    1. Crystal Structure of a Cytochrome P450 2B6 Genetic Variant in Complex with the Inhibitor 4-(4-Chlorophenyl)imidazole at 2.0-Å Resolution
      Sean C. Gay, Manish B. Shah, Jyothi C. Talakad, Keiko Maekawa, Arthur G. Roberts, P. Ross Wilderman, Ling Sun, Jane Y. Yang, Stephanie C. Huelga, Wen-Xu Hong, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology April 2010, 77 (4) 529-538; DOI: https://doi.org/10.1124/mol.109.062570
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