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Research ArticleArticle

Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ

Nanang Fakhrudin, Angela Ladurner, Atanas G. Atanasov, Elke H. Heiss, Lisa Baumgartner, Patrick Markt, Daniela Schuster, Ernst P. Ellmerer, Gerhard Wolber, Judith M. Rollinger, Hermann Stuppner and Verena M. Dirsch
Molecular Pharmacology April 2010, 77 (4) 559-566; DOI: https://doi.org/10.1124/mol.109.062141

Article Information

vol. 77 no. 4 559-566
DOI 
https://doi.org/10.1124/mol.109.062141
PubMed 
20064974
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received November 6, 2009
  • Accepted January 8, 2010
  • Published online March 18, 2010.

Article Versions

Copyright & Usage 
Copyright © 2010 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Nanang Fakhrudin1,
  2. Angela Ladurner,
  3. Atanas G. Atanasov,
  4. Elke H. Heiss,
  5. Lisa Baumgartner,
  6. Patrick Markt,
  7. Daniela Schuster,
  8. Ernst P. Ellmerer,
  9. Gerhard Wolber,
  10. Judith M. Rollinger,
  11. Hermann Stuppner and
  12. Verena M. Dirsch
  1. Department of Pharmacognosy, Faculty of Life Sciences, University of Vienna, Vienna, Austria (N.F., A.L., A.G.A., E.H.H., V.M.D.); Institute of Pharmacy/Pharmacognosy (L.B., J.M.R., H.S.), Institute of Pharmacy/Pharmaceutical Chemistry (L.B., J.M.R., H.S.), Center for Molecular Biosciences Innsbruck (L.B., P.M., D.S., J.M.R., G.W., H.S.), and Institute of Organic Chemistry (E.P.E.), University of Innsbruck, Innsbruck, Austria; and Inte:Ligand GmbH, Vienna, Austria (P.M., G.W.)
  1. Address correspondence to:
    Atanas Georgiev Atanasov, University of Vienna, Department of Pharmacognosy, Faculty of Life Sciences, Althanstrasse 14, 1090 Vienna, Austria. E-mail: atanas.atanasov{at}univie.ac.at

  • ↵1 N.F. is a permanent member of the Faculty of Pharmacy, Gadjah Mada University, Sekip Utara, Yogyakarta, Indonesia.

  1. N.F. and A.L. contributed equally to this work.

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Research ArticleArticle

Computer-Aided Discovery, Validation, and Mechanistic Characterization of Novel Neolignan Activators of Peroxisome Proliferator-Activated Receptor γ

Nanang Fakhrudin, Angela Ladurner, Atanas G. Atanasov, Elke H. Heiss, Lisa Baumgartner, Patrick Markt, Daniela Schuster, Ernst P. Ellmerer, Gerhard Wolber, Judith M. Rollinger, Hermann Stuppner and Verena M. Dirsch
Molecular Pharmacology April 1, 2010, 77 (4) 559-566; DOI: https://doi.org/10.1124/mol.109.062141
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