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Molecular Pharmacology

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Table of Contents

May 01, 2010; Volume 77,Issue 5

Articles

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    Restoring Blood-Brain Barrier P-Glycoprotein Reduces Brain Amyloid-β in a Mouse Model of Alzheimer's Disease
    Anika M. S. Hartz, David S. Miller and Björn Bauer
    Molecular Pharmacology May 2010, 77 (5) 715-723; DOI: https://doi.org/10.1124/mol.109.061754
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    A Cell-Based High-Throughput Screen Validates the Plasmodial Surface Anion Channel As an Antimalarial Target
    Ajay D. Pillai, Margaret Pain, Tsione Solomon, Abdullah A. B. Bokhari and Sanjay A. Desai
    Molecular Pharmacology May 2010, 77 (5) 724-733; DOI: https://doi.org/10.1124/mol.109.062711
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    Molecular Determinants of Ligand Binding to H4R Species Variants
    Herman D. Lim, Chris de Graaf, Wen Jiang, Payman Sadek, Patricia M. McGovern, Enade P. Istyastono, Remko A. Bakker, Iwan J. P. de Esch, Robin L. Thurmond and Rob Leurs
    Molecular Pharmacology May 2010, 77 (5) 734-743; DOI: https://doi.org/10.1124/mol.109.063040
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    Estrogen Receptor β Is a Novel Therapeutic Target for Photoaging
    Ken C. N. Chang, Yihe Wang, Inn Gyung Oh, Susan Jenkins, Leonard P. Freedman, Catherine C. Thompson, Jin Ho Chung and Sunil Nagpal
    Molecular Pharmacology May 2010, 77 (5) 744-750; DOI: https://doi.org/10.1124/mol.109.062877
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    Molecular Basis for a High-Potency Open-Channel Block of Kv1.5 Channel by the Endocannabinoid Anandamide
    Eloy G. Moreno-Galindo, Gabriel F. Barrio-Echavarría, José C. Vásquez, Niels Decher, Frank B. Sachse, Martin Tristani-Firouzi, José A. Sánchez-Chapula and Ricardo A. Navarro-Polanco
    Molecular Pharmacology May 2010, 77 (5) 751-758; DOI: https://doi.org/10.1124/mol.109.063008
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    H2 Relaxin Is a Biased Ligand Relative to H3 Relaxin at the Relaxin Family Peptide Receptor 3 (RXFP3)
    Emma T. van der Westhuizen, Arthur Christopoulos, Patrick M. Sexton, John D. Wade and Roger J. Summers
    Molecular Pharmacology May 2010, 77 (5) 759-772; DOI: https://doi.org/10.1124/mol.109.061432
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    Identification of Stage-Specific Gene Modulation during Early Thymocyte Development by Whole-Genome Profiling Analysis after Aryl Hydrocarbon Receptor Activation
    Michael D. Laiosa, Jeffrey H. Mills, Zhi-Wei Lai, Kameshwar P. Singh, Frank A. Middleton, Thomas A. Gasiewicz and Allen E. Silverstone
    Molecular Pharmacology May 2010, 77 (5) 773-783; DOI: https://doi.org/10.1124/mol.109.062497
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    Inhibitor of κB Kinase β Regulates Redox Homeostasis by Controlling the Constitutive Levels of Glutathione
    Zhimin Peng, Esmond Geh, Liang Chen, Qinghang Meng, Yunxia Fan, Maureen Sartor, Howard G. Shertzer, Zheng-Gang Liu, Alvaro Puga and Ying Xia
    Molecular Pharmacology May 2010, 77 (5) 784-792; DOI: https://doi.org/10.1124/mol.109.061424
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    Ethanol Reduces GABAA α1 Subunit Receptor Surface Expression by a Protein Kinase Cγ-Dependent Mechanism in Cultured Cerebral Cortical Neurons
    Sandeep Kumar, Asha Suryanarayanan, Kevin N. Boyd, Chris E. Comerford, Marvin A. Lai, Qinglu Ren and A. Leslie Morrow
    Molecular Pharmacology May 2010, 77 (5) 793-803; DOI: https://doi.org/10.1124/mol.109.063016
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    Modulation of Silent and Constitutively Active Nociceptin/Orphanin FQ Receptors by Potent Receptor Antagonists and Na+ Ions in Rat Sympathetic Neurons
    Saifeldin Mahmoud, Wojciech Margas, Claudio Trapella, Girolamo Caló and Victor Ruiz-Velasco
    Molecular Pharmacology May 2010, 77 (5) 804-817; DOI: https://doi.org/10.1124/mol.109.062208
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    Escin, a Pentacyclic Triterpene, Chemosensitizes Human Tumor Cells through Inhibition of Nuclear Factor-κB Signaling Pathway
    Kuzhuvelil B. Harikumar, Bokyung Sung, Manoj K. Pandey, Sushovan Guha, Sunil Krishnan and Bharat B. Aggarwal
    Molecular Pharmacology May 2010, 77 (5) 818-827; DOI: https://doi.org/10.1124/mol.109.062760
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    Arsenic Trioxide-Dependent Activation of Thousand-and-One Amino Acid Kinase 2 and Transforming Growth Factor-β-Activated Kinase 1
    Jennifer L. McNeer, Dennis J. Goussetis, Antonella Sassano, Blazej Dolniak, Barbara Kroczynska, Heather Glaser, Jessica K. Altman and Leonidas C. Platanias
    Molecular Pharmacology May 2010, 77 (5) 828-835; DOI: https://doi.org/10.1124/mol.109.061507
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    Functional Characterization of Vasopressin Type 2 Receptor Substitutions (R137H/C/L) Leading to Nephrogenic Diabetes Insipidus and Nephrogenic Syndrome of Inappropriate Antidiuresis: Implications for Treatments
    Moulay D. Rochdi, Gabriel A. Vargas, Eric Carpentier, Geneviève Oligny-Longpré, Stanford Chen, Abraham Kovoor, Stephen E. Gitelman, Stephen M. Rosenthal, Mark von Zastrow and Michel Bouvier
    Molecular Pharmacology May 2010, 77 (5) 836-845; DOI: https://doi.org/10.1124/mol.109.061804
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    Long-Term Duloxetine Treatment Normalizes Altered Brain-Derived Neurotrophic Factor Expression in Serotonin Transporter Knockout Rats through the Modulation of Specific Neurotrophin Isoforms
    Francesca Calabrese, Raffaella Molteni, Annamaria Cattaneo, Flavia Macchi, Giorgio Racagni, Massimo Gennarelli, Bart A. Ellenbroek and Marco A. Riva
    Molecular Pharmacology May 2010, 77 (5) 846-853; DOI: https://doi.org/10.1124/mol.109.063081
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    The Synthetic Cannabinoid WIN 55,212-2 Sensitizes Hepatocellular Carcinoma Cells to Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL)-Induced Apoptosis by Activating p8/CCAAT/Enhancer Binding Protein Homologous Protein (CHOP)/Death Receptor 5 (DR5) Axis
    O. Pellerito, G. Calvaruso, P. Portanova, A. De Blasio, A. Santulli, R. Vento, G. Tesoriere and M. Giuliano
    Molecular Pharmacology May 2010, 77 (5) 854-863; DOI: https://doi.org/10.1124/mol.109.062257
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    Effects of Corticotropin-Releasing Factor Receptor-1 Antagonists on the Brain Stress System Responses to Morphine Withdrawal
    Javier Navarro-Zaragoza, Cristina Núñez, M. Luisa Laorden and M. Victoria Milanés
    Molecular Pharmacology May 2010, 77 (5) 864-873; DOI: https://doi.org/10.1124/mol.109.062463
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    Increased Insertion of Glutamate Receptor 2-Lacking α-Amino-3-hydroxy-5-methyl-4-isoxazole Propionic Acid (AMPA) Receptors at Hippocampal Synapses upon Repeated Morphine Administration
    Sophie K. Billa, Jie Liu, Nicole L. Bjorklund, Namita Sinha, Yu Fu, Patricia Shinnick-Gallagher and Jose A. Morón
    Molecular Pharmacology May 2010, 77 (5) 874-883; DOI: https://doi.org/10.1124/mol.109.060301

Errata

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    Correction to “Glutamatergic (N-Methyl-d-aspartate Receptor) Hypofrontality in Schizophrenia: Too Little Juice or a Miswired Brain?”
    Molecular Pharmacology May 2010, 77 (5) 884; DOI: https://doi.org/10.1124/mol.77.5.884
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    Correction to “Vitamin D3 and Its Nuclear Receptor Increase the Expression and Activity of the Human Proton-Coupled Folate Transporter”
    Molecular Pharmacology May 2010, 77 (5) 885; DOI: https://doi.org/10.1124/mol.77.5.885
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In this issue

Molecular Pharmacology: 77 (5)
Molecular Pharmacology
Vol. 77, Issue 5
1 May 2010
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  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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