Table of Contents

Articles

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  High-Throughput Multiplexed Transcript Analysis Yields Enhanced Resolution of 5-Hydroxytryptamine_2C Receptor mRNA Editing Profiles

  Michael V. Morabito, Randi J. Ulbricht, Richard T. O'Neil, David C. Airey, Pengcheng Lu, Bing Zhang, Lily Wang and Ronald B. Emeson

  Molecular Pharmacology June 2010, 77 (6) 895-902; DOI: https://doi.org/10.1124/mol.109.061903
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  The Angiotensin II Type 1 Receptor Induces Membrane Blebbing by Coupling to Rho A, Rho Kinase, and Myosin Light Chain Kinase

  Christina M. Godin and Stephen S. G. Ferguson

  Molecular Pharmacology June 2010, 77 (6) 903-911; DOI: https://doi.org/10.1124/mol.110.063859
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  Regulation of Copper Transporter 2 Expression by Copper and Cisplatin in Human Ovarian Carcinoma Cells

  Brian G. Blair, Christopher A. Larson, Preston L. Adams, Paolo B. Abada, Roohangiz Safaei and Stephen B. Howell

  Molecular Pharmacology June 2010, 77 (6) 912-921; DOI: https://doi.org/10.1124/mol.109.062836
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  Correction of the ΔPhe508 Cystic Fibrosis Transmembrane Conductance Regulator Trafficking Defect by the Bioavailable Compound Glafenine

  Renaud Robert, Graeme W. Carlile, Jie Liao, Haouaria Balghi, Pierre Lesimple, Na Liu, Bart Kus, Daniela Rotin, Martina Wilke, Hugo R. de Jonge, Bob J. Scholte, David Y. Thomas and John W. Hanrahan

  Molecular Pharmacology June 2010, 77 (6) 922-930; DOI: https://doi.org/10.1124/mol.109.062679
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  A Molecular Model of the Human UDP-Glucuronosyltransferase 1A1, Its Membrane Orientation, and the Interactions between Different Parts of the Enzyme

  Liisa Laakkonen and Moshe Finel

  Molecular Pharmacology June 2010, 77 (6) 931-939; DOI: https://doi.org/10.1124/mol.109.063289
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  Pharmacochaperoning of the A₁ Adenosine Receptor Is Contingent on the Endoplasmic Reticulum

  Laura Málaga-Diéguez, Qiong Yang, Jan Bauer, Halyna Pankevych, Michael Freissmuth and Christian Nanoff

  Molecular Pharmacology June 2010, 77 (6) 940-952; DOI: https://doi.org/10.1124/mol.110.063511
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  Genetic and Functional Analysis of Human P2X5 Reveals a Distinct Pattern of Exon 10 Polymorphism with Predominant Expression of the Nonfunctional Receptor Isoform

  Smita Kotnis, Brendan Bingham, Dmitry V. Vasilyev, Scott W. Miller, Yuchen Bai, Sarita Yeola, Pranab K. Chanda, Mark R. Bowlby, Edward J. Kaftan, Tarek A. Samad and Garth T. Whiteside

  Molecular Pharmacology June 2010, 77 (6) 953-960; DOI: https://doi.org/10.1124/mol.110.063636
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  Identification of Hydroxyxanthones as Na/K-ATPase Ligands

  Zhongbing Zhang, Zhichuan Li, Jiang Tian, Wei Jiang, Yin Wang, Xiaojin Zhang, Zhuorong Li, Qidong You, Joseph I. Shapiro, Shuyi Si and Zijian Xie

  Molecular Pharmacology June 2010, 77 (6) 961-967; DOI: https://doi.org/10.1124/mol.110.063974
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  Priming of Signal Transducer and Activator of Transcription Proteins for Cytokine-Triggered Polyubiquitylation and Degradation by the A_2A Adenosine Receptor

  Mohammed M. A. Safhi, Claire Rutherford, Catherine Ledent, William A. Sands and Timothy M. Palmer

  Molecular Pharmacology June 2010, 77 (6) 968-978; DOI: https://doi.org/10.1124/mol.109.062455
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  Asymmetric Acetylation of the Cyclooxygenase-2 Homodimer by Aspirin and Its Effects on the Oxygenation of Arachidonic, Eicosapentaenoic, and Docosahexaenoic Acids

  Narayan P. Sharma, Liang Dong, Chong Yuan, Kathleen R. Noon and William L. Smith

  Molecular Pharmacology June 2010, 77 (6) 979-986; DOI: https://doi.org/10.1124/mol.109.063115
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  Up-Regulation of Human CYP2J2 in HepG2 Cells by Butylated Hydroxyanisole Is Mediated by c-Jun and Nrf2

  Andy C. Lee and Michael Murray

  Molecular Pharmacology June 2010, 77 (6) 987-994; DOI: https://doi.org/10.1124/mol.109.062729
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  Binding of Inositol 1,4,5-trisphosphate (IP₃) and Adenophostin A to the N-Terminal region of the IP₃ Receptor: Thermodynamic Analysis Using Fluorescence Polarization with a Novel IP₃ Receptor Ligand

  Zhao Ding, Ana M. Rossi, Andrew M. Riley, Taufiq Rahman, Barry V. L. Potter and Colin W. Taylor

  Molecular Pharmacology June 2010, 77 (6) 995-1004; DOI: https://doi.org/10.1124/mol.109.062596
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  PAR1 and PAR2 Couple to Overlapping and Distinct Sets of G Proteins and Linked Signaling Pathways to Differentially Regulate Cell Physiology

  Kelly L. McCoy, Stephen F. Traynelis and John R. Hepler

  Molecular Pharmacology June 2010, 77 (6) 1005-1015; DOI: https://doi.org/10.1124/mol.109.062018
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  MicroRNA-34a Inhibits Cell Proliferation by Repressing Mitogen-Activated Protein Kinase Kinase 1 during Megakaryocytic Differentiation of K562 Cells

  Atsuhiko Ichimura, Yoshinao Ruike, Kazuya Terasawa, Kazuharu Shimizu and Gozoh Tsujimoto

  Molecular Pharmacology June 2010, 77 (6) 1016-1024; DOI: https://doi.org/10.1124/mol.109.063321
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  EP1 Prostanoid Receptor Coupling to G_i/o Up-Regulates the Expression of Hypoxia-Inducible Factor-1α through Activation of a Phosphoinositide-3 Kinase Signaling Pathway

  Ruyue Ji, Chih-Ling Chou, Wei Xu, Xiao-Bo Chen, David F. Woodward and John W. Regan

  Molecular Pharmacology June 2010, 77 (6) 1025-1036; DOI: https://doi.org/10.1124/mol.110.063933
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  Amino Acid Substitutions in the Aryl Hydrocarbon Receptor Ligand Binding Domain Reveal YH439 As an Atypical AhR Activator

  Fiona Whelan, Nan Hao, Sebastian G. B. Furness, Murray L. Whitelaw and Anne Chapman-Smith

  Molecular Pharmacology June 2010, 77 (6) 1037-1046; DOI: https://doi.org/10.1124/mol.109.062927