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Molecular Pharmacology

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Table of Contents

June 01, 2010; Volume 77,Issue 6

MINIREVIEWS

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    Copper Transporters and the Cellular Pharmacology of the Platinum-Containing Cancer Drugs
    Stephen B. Howell, Roohangiz Safaei, Christopher A. Larson and Michael J. Sailor
    Molecular Pharmacology June 2010, 77 (6) 887-894; DOI: https://doi.org/10.1124/mol.109.063172

Articles

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    High-Throughput Multiplexed Transcript Analysis Yields Enhanced Resolution of 5-Hydroxytryptamine2C Receptor mRNA Editing Profiles
    Michael V. Morabito, Randi J. Ulbricht, Richard T. O'Neil, David C. Airey, Pengcheng Lu, Bing Zhang, Lily Wang and Ronald B. Emeson
    Molecular Pharmacology June 2010, 77 (6) 895-902; DOI: https://doi.org/10.1124/mol.109.061903
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    The Angiotensin II Type 1 Receptor Induces Membrane Blebbing by Coupling to Rho A, Rho Kinase, and Myosin Light Chain Kinase
    Christina M. Godin and Stephen S. G. Ferguson
    Molecular Pharmacology June 2010, 77 (6) 903-911; DOI: https://doi.org/10.1124/mol.110.063859
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    Regulation of Copper Transporter 2 Expression by Copper and Cisplatin in Human Ovarian Carcinoma Cells
    Brian G. Blair, Christopher A. Larson, Preston L. Adams, Paolo B. Abada, Roohangiz Safaei and Stephen B. Howell
    Molecular Pharmacology June 2010, 77 (6) 912-921; DOI: https://doi.org/10.1124/mol.109.062836
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    Correction of the ΔPhe508 Cystic Fibrosis Transmembrane Conductance Regulator Trafficking Defect by the Bioavailable Compound Glafenine
    Renaud Robert, Graeme W. Carlile, Jie Liao, Haouaria Balghi, Pierre Lesimple, Na Liu, Bart Kus, Daniela Rotin, Martina Wilke, Hugo R. de Jonge, Bob J. Scholte, David Y. Thomas and John W. Hanrahan
    Molecular Pharmacology June 2010, 77 (6) 922-930; DOI: https://doi.org/10.1124/mol.109.062679
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    A Molecular Model of the Human UDP-Glucuronosyltransferase 1A1, Its Membrane Orientation, and the Interactions between Different Parts of the Enzyme
    Liisa Laakkonen and Moshe Finel
    Molecular Pharmacology June 2010, 77 (6) 931-939; DOI: https://doi.org/10.1124/mol.109.063289
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    Pharmacochaperoning of the A1 Adenosine Receptor Is Contingent on the Endoplasmic Reticulum
    Laura Málaga-Diéguez, Qiong Yang, Jan Bauer, Halyna Pankevych, Michael Freissmuth and Christian Nanoff
    Molecular Pharmacology June 2010, 77 (6) 940-952; DOI: https://doi.org/10.1124/mol.110.063511
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    Genetic and Functional Analysis of Human P2X5 Reveals a Distinct Pattern of Exon 10 Polymorphism with Predominant Expression of the Nonfunctional Receptor Isoform
    Smita Kotnis, Brendan Bingham, Dmitry V. Vasilyev, Scott W. Miller, Yuchen Bai, Sarita Yeola, Pranab K. Chanda, Mark R. Bowlby, Edward J. Kaftan, Tarek A. Samad and Garth T. Whiteside
    Molecular Pharmacology June 2010, 77 (6) 953-960; DOI: https://doi.org/10.1124/mol.110.063636
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    Identification of Hydroxyxanthones as Na/K-ATPase Ligands
    Zhongbing Zhang, Zhichuan Li, Jiang Tian, Wei Jiang, Yin Wang, Xiaojin Zhang, Zhuorong Li, Qidong You, Joseph I. Shapiro, Shuyi Si and Zijian Xie
    Molecular Pharmacology June 2010, 77 (6) 961-967; DOI: https://doi.org/10.1124/mol.110.063974
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    Priming of Signal Transducer and Activator of Transcription Proteins for Cytokine-Triggered Polyubiquitylation and Degradation by the A2A Adenosine Receptor
    Mohammed M. A. Safhi, Claire Rutherford, Catherine Ledent, William A. Sands and Timothy M. Palmer
    Molecular Pharmacology June 2010, 77 (6) 968-978; DOI: https://doi.org/10.1124/mol.109.062455
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    Asymmetric Acetylation of the Cyclooxygenase-2 Homodimer by Aspirin and Its Effects on the Oxygenation of Arachidonic, Eicosapentaenoic, and Docosahexaenoic Acids
    Narayan P. Sharma, Liang Dong, Chong Yuan, Kathleen R. Noon and William L. Smith
    Molecular Pharmacology June 2010, 77 (6) 979-986; DOI: https://doi.org/10.1124/mol.109.063115
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    Up-Regulation of Human CYP2J2 in HepG2 Cells by Butylated Hydroxyanisole Is Mediated by c-Jun and Nrf2
    Andy C. Lee and Michael Murray
    Molecular Pharmacology June 2010, 77 (6) 987-994; DOI: https://doi.org/10.1124/mol.109.062729
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    Binding of Inositol 1,4,5-trisphosphate (IP3) and Adenophostin A to the N-Terminal region of the IP3 Receptor: Thermodynamic Analysis Using Fluorescence Polarization with a Novel IP3 Receptor Ligand
    Zhao Ding, Ana M. Rossi, Andrew M. Riley, Taufiq Rahman, Barry V. L. Potter and Colin W. Taylor
    Molecular Pharmacology June 2010, 77 (6) 995-1004; DOI: https://doi.org/10.1124/mol.109.062596
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    PAR1 and PAR2 Couple to Overlapping and Distinct Sets of G Proteins and Linked Signaling Pathways to Differentially Regulate Cell Physiology
    Kelly L. McCoy, Stephen F. Traynelis and John R. Hepler
    Molecular Pharmacology June 2010, 77 (6) 1005-1015; DOI: https://doi.org/10.1124/mol.109.062018
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    MicroRNA-34a Inhibits Cell Proliferation by Repressing Mitogen-Activated Protein Kinase Kinase 1 during Megakaryocytic Differentiation of K562 Cells
    Atsuhiko Ichimura, Yoshinao Ruike, Kazuya Terasawa, Kazuharu Shimizu and Gozoh Tsujimoto
    Molecular Pharmacology June 2010, 77 (6) 1016-1024; DOI: https://doi.org/10.1124/mol.109.063321
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    EP1 Prostanoid Receptor Coupling to Gi/o Up-Regulates the Expression of Hypoxia-Inducible Factor-1α through Activation of a Phosphoinositide-3 Kinase Signaling Pathway
    Ruyue Ji, Chih-Ling Chou, Wei Xu, Xiao-Bo Chen, David F. Woodward and John W. Regan
    Molecular Pharmacology June 2010, 77 (6) 1025-1036; DOI: https://doi.org/10.1124/mol.110.063933
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    Amino Acid Substitutions in the Aryl Hydrocarbon Receptor Ligand Binding Domain Reveal YH439 As an Atypical AhR Activator
    Fiona Whelan, Nan Hao, Sebastian G. B. Furness, Murray L. Whitelaw and Anne Chapman-Smith
    Molecular Pharmacology June 2010, 77 (6) 1037-1046; DOI: https://doi.org/10.1124/mol.109.062927
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In this issue

Molecular Pharmacology: 77 (6)
Molecular Pharmacology
Vol. 77, Issue 6
1 Jun 2010
  • Table of Contents
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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