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Research ArticleArticle

Asymmetric Acetylation of the Cyclooxygenase-2 Homodimer by Aspirin and Its Effects on the Oxygenation of Arachidonic, Eicosapentaenoic, and Docosahexaenoic Acids

Narayan P. Sharma, Liang Dong, Chong Yuan, Kathleen R. Noon and William L. Smith
Molecular Pharmacology June 2010, 77 (6) 979-986; DOI: https://doi.org/10.1124/mol.109.063115

Article Information

vol. 77 no. 6 979-986
DOI 
https://doi.org/10.1124/mol.109.063115
PubMed 
20194532
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received December 13, 2009
  • Accepted March 1, 2010
  • Published online May 17, 2010.

Article Versions

Copyright & Usage 
Copyright © 2010 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Narayan P. Sharma,
  2. Liang Dong,
  3. Chong Yuan,
  4. Kathleen R. Noon and
  5. William L. Smith
  1. Departments of Biological Chemistry (N.P.S., L.D., C.Y., W.L.S.) and Pharmacology (K.R.N.), University of Michigan, Ann Arbor, Michigan
  1. Address correspondence to:
    Dr. William L. Smith, Department of Biological Chemistry, University of Michigan Medical School, 1150 West Medical Center Drive, 5301 MSRB III, Ann Arbor, MI 48109-0606. E-mail: smithww{at}umich.edu
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Research ArticleArticle

Asymmetric Acetylation of the Cyclooxygenase-2 Homodimer by Aspirin and Its Effects on the Oxygenation of Arachidonic, Eicosapentaenoic, and Docosahexaenoic Acids

Narayan P. Sharma, Liang Dong, Chong Yuan, Kathleen R. Noon and William L. Smith
Molecular Pharmacology June 1, 2010, 77 (6) 979-986; DOI: https://doi.org/10.1124/mol.109.063115
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