Table of Contents

Articles

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  The Human Concentrative Nucleoside Transporter-3 C602R Variant Shows Impaired Sorting to Lipid Rafts and Altered Specificity for Nucleoside-Derived Drugs

  Ekaitz Errasti-Murugarren, Miriam Molina-Arcas, F. Javier Casado and Marçal Pastor-Anglada

  Molecular Pharmacology August 2010, 78 (2) 157-165; DOI: https://doi.org/10.1124/mol.110.063552
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  Survival of Human Multiple Myeloma Cells Is Dependent on MUC1 C-Terminal Transmembrane Subunit Oncoprotein Function

  Li Yin, Rehan Ahmad, Michio Kosugi, Turner Kufe, Baldev Vasir, David Avigan, Surender Kharbanda and Donald Kufe

  Molecular Pharmacology August 2010, 78 (2) 166-174; DOI: https://doi.org/10.1124/mol.110.065011
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  Aryl Hydrocarbon Receptor Is a Transcriptional Activator of the Human Breast Cancer Resistance Protein (BCRP/ABCG2)

  Kah Poh Tan, Bernice Wang, Mingdong Yang, Paul C. Boutros, Jane MacAulay, Haibo Xu, Andrew I. Chuang, Kazuhiro Kosuge, Mika Yamamoto, Shinichiro Takahashi, Alex M. L. Wu, Douglas D. Ross, Patricia A. Harper and Shinya Ito

  Molecular Pharmacology August 2010, 78 (2) 175-185; DOI: https://doi.org/10.1124/mol.110.065078
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  Post-Transcriptional Control of Human Ether-a-go-go-Related Gene Potassium Channel Protein by α-Adrenergic Receptor Stimulation

  Jian Chen, Kun Chen, Jakub Sroubek, Zhi-Yuan Wu, Dierk Thomas, Jin-Song Bian and Thomas V. McDonald

  Molecular Pharmacology August 2010, 78 (2) 186-197; DOI: https://doi.org/10.1124/mol.109.062216
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  Nicotinic Acetylcholine Receptor Transmembrane Mutations Convert Ivermectin from a Positive to a Negative Allosteric Modulator

  Toby Collins and Neil S. Millar

  Molecular Pharmacology August 2010, 78 (2) 198-204; DOI: https://doi.org/10.1124/mol.110.064295
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  Prediction of Functionally Selective Allosteric Interactions at an M₃ Muscarinic Acetylcholine Receptor Mutant Using Saccharomyces cerevisiae

  Gregory D. Stewart, Patrick M. Sexton and Arthur Christopoulos

  Molecular Pharmacology August 2010, 78 (2) 205-214; DOI: https://doi.org/10.1124/mol.110.064253
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  Stimulation of the Liver X Receptor Pathway Inhibits HIV-1 Replication via Induction of ATP-Binding Cassette Transporter A1

  Matthew P. Morrow, Angela Grant, Zahedi Mujawar, Larisa Dubrovsky, Tatiana Pushkarsky, Yana Kiselyeva, Lucas Jennelle, Nigora Mukhamedova, Alan T. Remaley, Fatah Kashanchi, Dmitri Sviridov and Michael Bukrinsky

  Molecular Pharmacology August 2010, 78 (2) 215-225; DOI: https://doi.org/10.1124/mol.110.065029
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  Methyl 2-Cyano-3,12-dioxooleana-1,9-dien-28-oate Decreases Specificity Protein Transcription Factors and Inhibits Pancreatic Tumor Growth: Role of MicroRNA-27a

  Indira Jutooru, Gayathri Chadalapaka, Maen Abdelrahim, Md Riyaz Basha, Ismael Samudio, Marina Konopleva, Michael Andreeff and Stephen Safe

  Molecular Pharmacology August 2010, 78 (2) 226-236; DOI: https://doi.org/10.1124/mol.110.064451
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  Octopamine Receptors from the Barnacle Balanus improvisus Are Activated by the α₂-Adrenoceptor Agonist Medetomidine

  Ulrika Lind, Magnus Alm Rosenblad, Linda Hasselberg Frank, Susanna Falkbring, Lars Brive, Jonne M. Laurila, Katariina Pohjanoksa, Anne Vuorenpää, Jyrki P. Kukkonen, Lina Gunnarsson, Mika Scheinin, Lena G. E. Mårtensson Lindblad and Anders Blomberg

  Molecular Pharmacology August 2010, 78 (2) 237-248; DOI: https://doi.org/10.1124/mol.110.063594
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  Sensory Neuron-Specific Mas-Related Gene-X1 Receptors Resist Agonist-Promoted Endocytosis

  Hans Jürgen Solinski, Ingrid Boekhoff, Michel Bouvier, Thomas Gudermann and Andreas Breit

  Molecular Pharmacology August 2010, 78 (2) 249-259; DOI: https://doi.org/10.1124/mol.110.063867
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  Preservation of Striatal Cannabinoid CB1 Receptor Function Correlates with the Antianxiety Effects of Fatty Acid Amide Hydrolase Inhibition

  Silvia Rossi, Valentina De Chiara, Alessandra Musella, Lucia Sacchetti, Cristina Cantarella, Maura Castelli, Francesca Cavasinni, Caterina Motta, Valeria Studer, Giorgio Bernardi, Benjamin F. Cravatt, Mauro Maccarrone, Alessandro Usiello and Diego Centonze

  Molecular Pharmacology August 2010, 78 (2) 260-268; DOI: https://doi.org/10.1124/mol.110.064196
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  Deletion of Microsomal Cytochrome b₅ Profoundly Affects Hepatic and Extrahepatic Drug Metabolism

  Lesley A. McLaughlin, Sebastien Ronseaux, Robert D. Finn, Colin J. Henderson and C. Roland Wolf

  Molecular Pharmacology August 2010, 78 (2) 269-278; DOI: https://doi.org/10.1124/mol.110.064246
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  Enhanced Hypotensive, Bradycardic, and Hypnotic Responses to α₂-Adrenergic Agonists in Spinophilin-Null Mice Are Accompanied by Increased G Protein Coupling to the α_2A-Adrenergic Receptor

  R. Lu, Y. Chen, C. Cottingham, N. Peng, K. Jiao, L. E. Limbird, J. M. Wyss and Q. Wang

  Molecular Pharmacology August 2010, 78 (2) 279-286; DOI: https://doi.org/10.1124/mol.110.065300
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  A Comparative Study of the Effects of the Intravenous Self-Administration or Subcutaneous Minipump Infusion of Nicotine on the Expression of Brain Neuronal Nicotinic Receptor Subtypes

  Milena Moretti, Manolo Mugnaini, Michela Tessari, Michele Zoli, Annalisa Gaimarri, Irene Manfredi, Francesco Pistillo, Francesco Clementi and Cecilia Gotti

  Molecular Pharmacology August 2010, 78 (2) 287-296; DOI: https://doi.org/10.1124/mol.110.064071
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  Activation of Checkpoint Kinase 2 by 3,3′-Diindolylmethane Is Required for Causing G₂/M Cell Cycle Arrest in Human Ovarian Cancer Cells

  Prabodh K. Kandala and Sanjay K. Srivastava

  Molecular Pharmacology August 2010, 78 (2) 297-309; DOI: https://doi.org/10.1124/mol.110.063750
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  Pim-1 Kinase Protects P-Glycoprotein from Degradation and Enables Its Glycosylation and Cell Surface Expression

  Yingqiu Xie, Mehmet Burcu, Douglas E. Linn, Yun Qiu and Maria R. Baer

  Molecular Pharmacology August 2010, 78 (2) 310-318; DOI: https://doi.org/10.1124/mol.109.061713
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  A Small-Molecule Oxocarbazate Inhibitor of Human Cathepsin L Blocks Severe Acute Respiratory Syndrome and Ebola Pseudotype Virus Infection into Human Embryonic Kidney 293T cells

  Parag P. Shah, Tianhua Wang, Rachel L. Kaletsky, Michael C. Myers, Jeremy E. Purvis, Huiyan Jing, Donna M. Huryn, Doron C. Greenbaum, Amos B. Smith, Paul Bates and Scott L. Diamond

  Molecular Pharmacology August 2010, 78 (2) 319-324; DOI: https://doi.org/10.1124/mol.110.064261