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Research ArticleArticle

Enhanced Hypotensive, Bradycardic, and Hypnotic Responses to α2-Adrenergic Agonists in Spinophilin-Null Mice Are Accompanied by Increased G Protein Coupling to the α2A-Adrenergic Receptor

R. Lu, Y. Chen, C. Cottingham, N. Peng, K. Jiao, L. E. Limbird, J. M. Wyss and Q. Wang
Molecular Pharmacology August 2010, 78 (2) 279-286; DOI: https://doi.org/10.1124/mol.110.065300

Article Information

vol. 78 no. 2 279-286
DOI 
https://doi.org/10.1124/mol.110.065300
PubMed 
20430865
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received April 2, 2010
  • Accepted April 29, 2010
  • Published online July 14, 2010.

Article Versions

Copyright & Usage 
Copyright © 2010 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. R. Lu,
  2. Y. Chen,
  3. C. Cottingham,
  4. N. Peng,
  5. K. Jiao,
  6. L. E. Limbird,
  7. J. M. Wyss and
  8. Q. Wang
  1. Departments of Physiology and Biophysics (R.L., Y.C., C.C., Q.W.), Cell Biology (N.P., J.M.W.) and Genetics (K.J.), University of Alabama at Birmingham, Birmingham, Alabama; and Department of Pharmacology, Vanderbilt University, Nashville, Tennessee (L.E.L.)
  1. Address correspondence to:
    Qin Wang, 986 MCLM, 1918 University Blvd., Birmingham, AL 35294. E-mail: qinwang{at}uab.edu

  1. R.L. and Y.C. contributed equally to this work.

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Research ArticleArticle

Enhanced Hypotensive, Bradycardic, and Hypnotic Responses to α2-Adrenergic Agonists in Spinophilin-Null Mice Are Accompanied by Increased G Protein Coupling to the α2A-Adrenergic Receptor

R. Lu, Y. Chen, C. Cottingham, N. Peng, K. Jiao, L. E. Limbird, J. M. Wyss and Q. Wang
Molecular Pharmacology August 1, 2010, 78 (2) 279-286; DOI: https://doi.org/10.1124/mol.110.065300
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