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Targeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid Tumors

Sita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, Mark Stout, Zhanjun Hou, Andreas Fulterer, Min-Hwang Chang, Michael F. Romero, Christina Cherian, Aleem Gangjee and Larry H. Matherly
Molecular Pharmacology October 2010, 78 (4) 577-587; DOI: https://doi.org/10.1124/mol.110.065896

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Research ArticleArticle

Targeting the Proton-Coupled Folate Transporter for Selective Delivery of 6-Substituted Pyrrolo[2,3-d]Pyrimidine Antifolate Inhibitors of De Novo Purine Biosynthesis in the Chemotherapy of Solid Tumors

Sita Kugel Desmoulin, Yiqiang Wang, Jianmei Wu, Mark Stout, Zhanjun Hou, Andreas Fulterer, Min-Hwang Chang, Michael F. Romero, Christina Cherian, Aleem Gangjee and Larry H. Matherly
Molecular Pharmacology October 1, 2010, 78 (4) 577-587; DOI: https://doi.org/10.1124/mol.110.065896
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