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Molecular Pharmacology

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Table of Contents

November 01, 2010; Volume 78,Issue 5

Articles

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    Different N-Terminal Motifs Determine Plasma Membrane Targeting of the Human Concentrative Nucleoside Transporter 3 in Polarized and Nonpolarized Cells
    Ekaitz Errasti-Murugarren, F. Javier Casado and Marçal Pastor-Anglada
    Molecular Pharmacology November 2010, 78 (5) 795-803; DOI: https://doi.org/10.1124/mol.110.065920
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    Structure-Activity Relationships of GPR120 Agonists Based on a Docking Simulation
    Qi Sun, Akira Hirasawa, Takafumi Hara, Ikuo Kimura, Tetsuya Adachi, Takeo Awaji, Masaji Ishiguro, Takayoshi Suzuki, Naoki Miyata and Gozoh Tsujimoto
    Molecular Pharmacology November 2010, 78 (5) 804-810; DOI: https://doi.org/10.1124/mol.110.066324
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    Lyn Kinase-Dependent Regulation of miR181 and Myeloid Cell Leukemia-1 Expression: Implications for Drug Resistance in Myelogenous Leukemia
    Eric I. Zimmerman, Claudia M. Dollins, Melissa Crawford, Steven Grant, Serge P. Nana-Sinkam, Kristy L. Richards, Scott M. Hammond and Lee M. Graves
    Molecular Pharmacology November 2010, 78 (5) 811-817; DOI: https://doi.org/10.1124/mol.110.066258
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    Constitutive Activity of Serotonin2C Receptors at G Protein-Independent Signaling: Modulation by RNA Editing and Antidepressants
    Marilyne Labasque, Julie Meffre, Gaelle Carrat, Carine Becamel, Joël Bockaert and Philippe Marin
    Molecular Pharmacology November 2010, 78 (5) 818-826; DOI: https://doi.org/10.1124/mol.110.066035
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    Auraptene Is an Inhibitor of Cholesterol Esterification and a Modulator of Estrogen Receptors
    Philippe de Medina, Salvatore Genovese, Michael R. Paillasse, Mahta Mazaheri, Stephanie Caze-Subra, Kerstin Bystricky, Massimo Curini, Sandrine Silvente-Poirot, Francesco Epifano and Marc Poirot
    Molecular Pharmacology November 2010, 78 (5) 827-836; DOI: https://doi.org/10.1124/mol.110.065250
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    The μ-Opioid Receptor Variant N190K Is Unresponsive to Peptide Agonists yet Can be Rescued by Small-Molecule Drugs
    Jean-Philippe Fortin, Lei Ci, Jonathan Schroeder, Carmit Goldstein, Maria Claudia Montefusco, Inga Peter, Steven E. Reis, Gordon S. Huggins, Martin Beinborn and Alan S. Kopin
    Molecular Pharmacology November 2010, 78 (5) 837-845; DOI: https://doi.org/10.1124/mol.110.064188
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    Pharmacological Targeting of Constitutively Active Truncated Androgen Receptor by Nigericin and Suppression of Hormone-Refractory Prostate Cancer Cell Growth
    Tetsuo Mashima, Sachiko Okabe and Hiroyuki Seimiya
    Molecular Pharmacology November 2010, 78 (5) 846-854; DOI: https://doi.org/10.1124/mol.110.064790
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    Amurensin G, a Potent Natural SIRT1 Inhibitor, Rescues Doxorubicin Responsiveness via Down-Regulation of Multidrug Resistance 1
    Won Keun Oh, Kyoung Bin Cho, Tran Thi Hien, Tae Hyung Kim, Hyung Sik Kim, Trong Tuan Dao, Hyo-Kyung Han, Seong-Min Kwon, Sang-Gun Ahn, Jung-Hoon Yoon, Tae Hyun Kim, Yoon Gyoon Kim and Keon Wook Kang
    Molecular Pharmacology November 2010, 78 (5) 855-864; DOI: https://doi.org/10.1124/mol.110.065961
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    Thapsigargin Induces Expression of Activating Transcription Factor 3 in Human Keratinocytes Involving Ca2+ Ions and c-Jun N-Terminal Protein Kinase
    Daniel Spohn, Oliver G. Rössler, Stephan E. Philipp, Michael Raubuch, Shigetaka Kitajima, Désirée Griesemer, Markus Hoth and Gerald Thiel
    Molecular Pharmacology November 2010, 78 (5) 865-876; DOI: https://doi.org/10.1124/mol.110.067637
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    A Nonthiazolidinedione Peroxisome Proliferator-Activated Receptor α/γ Dual Agonist CG301360 Alleviates Insulin Resistance and Lipid Dysregulation in db/db Mice
    Hyun Woo Jeong, Joo-Won Lee, Woo Sik Kim, Sung Sik Choe, Hyun Jung Shin, Gha Young Lee, Dongkyu Shin, Jun Hee Lee, Eun Bok Choi, Hyun Kyu Lee, Gyu Hwan Yon, Bongjun Cho, Hye Ryung Kim, Sung Hee Choi, Young Sun Chung, Seung Bum Park, Heekyoung Chung, Seonggu Ro and Jae Bum Kim
    Molecular Pharmacology November 2010, 78 (5) 877-885; DOI: https://doi.org/10.1124/mol.110.065748
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    Regulation of CYP2C19 Expression by Estrogen Receptor α: Implications for Estrogen-Dependent Inhibition of Drug Metabolism
    Jessica Mwinyi, Isa Cavaco, Rasmus Steen Pedersen, Anna Persson, Sabrina Burkhardt, Souren Mkrtchian and Magnus Ingelman-Sundberg
    Molecular Pharmacology November 2010, 78 (5) 886-894; DOI: https://doi.org/10.1124/mol.110.065540
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    Monepantel Allosterically Activates DEG-3/DES-2 Channels of the Gastrointestinal Nematode Haemonchus contortus
    Lucien Rufener, Roland Baur, Ronald Kaminsky, Pascal Mäser and Erwin Sigel
    Molecular Pharmacology November 2010, 78 (5) 895-902; DOI: https://doi.org/10.1124/mol.110.066498
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    Microtubule-Targeted Chemotherapeutic Agents Inhibit Signal Transducer and Activator of Transcription 3 (STAT3) Signaling
    Sarah R. Walker, Mousumi Chaudhury, Erik A. Nelson and David A. Frank
    Molecular Pharmacology November 2010, 78 (5) 903-908; DOI: https://doi.org/10.1124/mol.110.066316
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    Poly(ADP-Ribose) Polymerase 1 Modulates the Lethality of CHK1 Inhibitors in Carcinoma Cells
    Clint Mitchell, Margaret Park, Patrick Eulitt, Chen Yang, Adly Yacoub and Paul Dent
    Molecular Pharmacology November 2010, 78 (5) 909-917; DOI: https://doi.org/10.1124/mol.110.067199
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    Alcohol- and Alcohol Antagonist-Sensitive Human GABAA Receptors: Tracking δ Subunit Incorporation into Functional Receptors
    Pratap Meera, Richard W. Olsen, Thomas S. Otis and Martin Wallner
    Molecular Pharmacology November 2010, 78 (5) 918-924; DOI: https://doi.org/10.1124/mol.109.062687
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    The Tetrahydroisoquinoline Derivative SB269,652 Is an Allosteric Antagonist at Dopamine D3 and D2 Receptors
    Elena Silvano, Mark J. Millan, Clotilde Mannoury la Cour, Yang Han, Lihua Duan, Suzy A. Griffin, Robert R. Luedtke, Gabriella Aloisi, Mario Rossi, Francesca Zazzeroni, Jonathan A. Javitch and Roberto Maggio
    Molecular Pharmacology November 2010, 78 (5) 925-934; DOI: https://doi.org/10.1124/mol.110.065755
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    Morphine Regulates Dopaminergic Neuron Differentiation via miR-133b
    Fatima Macho Sanchez-Simon, Xiao Xiao Zhang, Horace H. Loh, Ping-Yee Law and Raquel E. Rodriguez
    Molecular Pharmacology November 2010, 78 (5) 935-942; DOI: https://doi.org/10.1124/mol.110.066837
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    Nijmegen Breakage Syndrome Protein (NBN) Causes Resistance to Methylating Anticancer Drugs Such as Temozolomide
    Marcus Eich, Wynand P. Roos, Grigory L. Dianov, Martin Digweed and Bernd Kaina
    Molecular Pharmacology November 2010, 78 (5) 943-951; DOI: https://doi.org/10.1124/mol.110.066076
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    Inhibition of Large-Conductance Ca2+-Activated K+ Channels by Nanomolar Concentrations of Ag+
    Yu Zhou, Xiaoming Xia and Christopher J. Lingle
    Molecular Pharmacology November 2010, 78 (5) 952-960; DOI: https://doi.org/10.1124/mol.110.066407
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    Discovery of Novel Forkhead Box O1 Inhibitors for Treating Type 2 Diabetes: Improvement of Fasting Glycemia in Diabetic db/db Mice
    Takeyuki Nagashima, Nobuharu Shigematsu, Riyo Maruki, Yasuharu Urano, Hirotsugu Tanaka, Akiyoshi Shimaya, Teruhiko Shimokawa and Masayuki Shibasaki
    Molecular Pharmacology November 2010, 78 (5) 961-970; DOI: https://doi.org/10.1124/mol.110.065714
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    α6β2* and α4β2* Nicotinic Receptors Both Regulate Dopamine Signaling with Increased Nigrostriatal Damage: Relevance to Parkinson's Disease
    Xiomara A. Perez, Tanuja Bordia, J. Michael McIntosh and Maryka Quik
    Molecular Pharmacology November 2010, 78 (5) 971-980; DOI: https://doi.org/10.1124/mol.110.067561

Erratum

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    Correction to “Resveratrol Protects Dopamine Neurons against Lipopolysaccharide-Induced Neurotoxicity through Its Anti-Inflammatory Actions”
    Molecular Pharmacology November 2010, 78 (5) 981; DOI: https://doi.org/10.1124/mol.78.5.981
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In this issue

Molecular Pharmacology: 78 (5)
Molecular Pharmacology
Vol. 78, Issue 5
1 Nov 2010
  • Table of Contents
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  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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