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Research ArticleArticle

Emetine Promotes von Hippel-Lindau-Independent Degradation of Hypoxia-Inducible Factor-2α in Clear Cell Renal Carcinoma

Hye-Sik Kong, Sunmin Lee, Kristin Beebe, Bradley Scroggins, Gopal Gupta, Min-Jung Lee, Yun-Jin Jung, Jane Trepel and Leonard Neckers
Molecular Pharmacology December 2010, 78 (6) 1072-1078; DOI: https://doi.org/10.1124/mol.110.066514

Article Information

vol. 78 no. 6 1072-1078
DOI 
https://doi.org/10.1124/mol.110.066514
PubMed 
20813864
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received May 19, 2010
  • Accepted September 2, 2010
  • Published online November 16, 2010.

Article Versions

Copyright & Usage 
Copyright © 2010 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Hye-Sik Kong,
  2. Sunmin Lee,
  3. Kristin Beebe,
  4. Bradley Scroggins,
  5. Gopal Gupta,
  6. Min-Jung Lee,
  7. Yun-Jin Jung,
  8. Jane Trepel and
  9. Leonard Neckers
  1. Urologic Oncology Branch (H.K., K.B., B.S., G.G., L.N.) and Medical Oncology Branch (S.L., M.L., J.T.), Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC (H.K.); and Laboratory of Biomedicinal Chemistry, College of Pharmacy, Pusan National University, Busan, Republic of Korea (Y.J.)
  1. Address correspondence to:
    Dr. Leonard Neckers, Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892. E-mail: neckersl{at}mail.nih.gov
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Research ArticleArticle

Emetine Promotes von Hippel-Lindau-Independent Degradation of Hypoxia-Inducible Factor-2α in Clear Cell Renal Carcinoma

Hye-Sik Kong, Sunmin Lee, Kristin Beebe, Bradley Scroggins, Gopal Gupta, Min-Jung Lee, Yun-Jin Jung, Jane Trepel and Leonard Neckers
Molecular Pharmacology December 1, 2010, 78 (6) 1072-1078; DOI: https://doi.org/10.1124/mol.110.066514
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