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Research ArticleArticle

Development of a Selective Small-Molecule Inhibitor of Kir1.1, the Renal Outer Medullary Potassium Channel

Gautam Bhave, Brian A. Chauder, Wen Liu, Eric S. Dawson, Rishin Kadakia, Thuy T. Nguyen, L. Michelle Lewis, Jens Meiler, C. David Weaver, Lisa M. Satlin, Craig W. Lindsley and Jerod S. Denton
Molecular Pharmacology January 2011, 79 (1) 42-50; DOI: https://doi.org/10.1124/mol.110.066928
Gautam Bhave
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Brian A. Chauder
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Wen Liu
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Eric S. Dawson
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Rishin Kadakia
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Thuy T. Nguyen
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L. Michelle Lewis
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Jens Meiler
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C. David Weaver
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Lisa M. Satlin
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Craig W. Lindsley
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Jerod S. Denton
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Article Information

vol. 79 no. 1 42-50
DOI 
https://doi.org/10.1124/mol.110.066928
PubMed 
20926757

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received June 14, 2010
  • Accepted October 6, 2010
  • Published online December 14, 2010.

Article Versions

  • Earlier version (October 6, 2010 - 12:05).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2011 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Gautam Bhave,
  2. Brian A. Chauder,
  3. Wen Liu,
  4. Eric S. Dawson,
  5. Rishin Kadakia,
  6. Thuy T. Nguyen,
  7. L. Michelle Lewis,
  8. Jens Meiler,
  9. C. David Weaver,
  10. Lisa M. Satlin,
  11. Craig W. Lindsley and
  12. Jerod S. Denton
  1. Departments of Anesthesiology (G.B., R.K., T.T.N., J.S.D.) and Pharmacology (T.T.N., J.M., C.D.W., J.S.D.), Division of Nephrology (G.B.), Institute of Chemical Biology (B.A.C., E.S.D., L.M.L., C.W.L., J.S.D.), Digestive Disease Research Center (J.S.D.), Vanderbilt University School of Medicine, Nashville, Tennessee; and Division of Pediatric Nephrology, Department of Pediatrics, Mount Sinai School of Medicine, New York, New York (W.L., L.M.S.)
  1. Address correspondence to:
    Dr. Jerod S. Denton, T4208 Medical Center North, 1161 21st Avenue South, Nashville, TN 37232. E-mail: jerod.s.denton{at}vanderbilt.edu
  1. G.B. and B.A.C. contributed equally to this work.

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Molecular Pharmacology: 79 (1)
Molecular Pharmacology
Vol. 79, Issue 1
1 Jan 2011
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Research ArticleArticle

Development of a Selective Small-Molecule Inhibitor of Kir1.1, the Renal Outer Medullary Potassium Channel

Gautam Bhave, Brian A. Chauder, Wen Liu, Eric S. Dawson, Rishin Kadakia, Thuy T. Nguyen, L. Michelle Lewis, Jens Meiler, C. David Weaver, Lisa M. Satlin, Craig W. Lindsley and Jerod S. Denton
Molecular Pharmacology January 1, 2011, 79 (1) 42-50; DOI: https://doi.org/10.1124/mol.110.066928

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Research ArticleArticle

Development of a Selective Small-Molecule Inhibitor of Kir1.1, the Renal Outer Medullary Potassium Channel

Gautam Bhave, Brian A. Chauder, Wen Liu, Eric S. Dawson, Rishin Kadakia, Thuy T. Nguyen, L. Michelle Lewis, Jens Meiler, C. David Weaver, Lisa M. Satlin, Craig W. Lindsley and Jerod S. Denton
Molecular Pharmacology January 1, 2011, 79 (1) 42-50; DOI: https://doi.org/10.1124/mol.110.066928
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