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Research ArticleArticle

Pharmacological Characterization of MK-7246, a Potent and Selective CRTH2 (Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type 2 Cells) Antagonist

Francois G. Gervais, Nicole Sawyer, Rino Stocco, Martine Hamel, Connie Krawczyk, Susan Sillaots, Danielle Denis, Elizabeth Wong, Zhaoyin Wang, Michel Gallant, William M. Abraham, Deborah Slipetz, Michael A. Crackower and Gary P. O'Neill
Molecular Pharmacology January 2011, 79 (1) 69-76; DOI: https://doi.org/10.1124/mol.110.068585

Article Information

vol. 79 no. 1 69-76
DOI 
https://doi.org/10.1124/mol.110.068585
PubMed 
20943773
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received September 2, 2010
  • Accepted October 5, 2010
  • Published online December 14, 2010.

Article Versions

Copyright & Usage 
Copyright © 2011 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Francois G. Gervais1,
  2. Nicole Sawyer,
  3. Rino Stocco,
  4. Martine Hamel,
  5. Connie Krawczyk,
  6. Susan Sillaots,
  7. Danielle Denis,
  8. Elizabeth Wong,
  9. Zhaoyin Wang,
  10. Michel Gallant,
  11. William M. Abraham2,
  12. Deborah Slipetz1,
  13. Michael A. Crackower1 and
  14. Gary P. O'Neill1
  1. Department of Biochemistry and Molecular Biology, Merck Frosst Centre for Therapeutic Research, Kirkland, Quebec, Canada
  1. Address correspondence to:
    Dr. Francois G. Gervais, Department of Respiratory and Inflammation, Merck Research Laboratories, 33 Avenue Louis Pasteur, Boston, MA 02115. E-mail: francois_gervais{at}merck.com

  • ↵1 Current affiliation: Department of Respiratory and Inflammation, Merck Research Laboratories, Boston, Massachusetts.

  • ↵2 Current affiliation: Department of Research, Mount Sinai Medical Center, Miami Beach, Florida.

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Research ArticleArticle

Pharmacological Characterization of MK-7246, a Potent and Selective CRTH2 (Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type 2 Cells) Antagonist

Francois G. Gervais, Nicole Sawyer, Rino Stocco, Martine Hamel, Connie Krawczyk, Susan Sillaots, Danielle Denis, Elizabeth Wong, Zhaoyin Wang, Michel Gallant, William M. Abraham, Deborah Slipetz, Michael A. Crackower and Gary P. O'Neill
Molecular Pharmacology January 1, 2011, 79 (1) 69-76; DOI: https://doi.org/10.1124/mol.110.068585
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