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Research ArticleArticle

A Structural Insight into the Reorientation of Transmembrane Domains 3 and 5 during Family A G Protein-Coupled Receptor Activation

Kamonchanok Sansuk, Xavier Deupi, Ivan R. Torrecillas, Aldo Jongejan, Saskia Nijmeijer, Remko A. Bakker, Leonardo Pardo and Rob Leurs
Molecular Pharmacology February 2011, 79 (2) 262-269; DOI: https://doi.org/10.1124/mol.110.066068

Article Information

vol. 79 no. 2 262-269
DOI 
https://doi.org/10.1124/mol.110.066068
PubMed 
21081645
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received May 5, 2010
  • Accepted November 16, 2010
  • Published online January 18, 2011.

Article Versions

Copyright & Usage 
Copyright © 2011 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Kamonchanok Sansuk,
  2. Xavier Deupi1,
  3. Ivan R. Torrecillas,
  4. Aldo Jongejan,
  5. Saskia Nijmeijer,
  6. Remko A. Bakker2,
  7. Leonardo Pardo and
  8. Rob Leurs
  1. Leiden/Amsterdam Center for Drug Research, Department of Medicinal Chemistry, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (K.S., A.J., S.N., R.A.B., R.L.); and Laboratori de Medicina Computacional, Unitat de Bioestadística, Facultat de Medicina, Universitat Autònoma de Barcelona, Bellaterra, Spain (X.D., I.R.T., L.P.)
  1. Address correspondence to:
    Dr. Rob Leurs, Leiden/Amsterdam Center for Drug Research, Department of Medicinal Chemistry, Vrije Universiteit Amsterdam, De Boelelaan 1083, 1081HV Amsterdam, the Netherlands. E-mail: leurs{at}few.vu.nl

  • ↵1 Current affiliation: Condensed Matter Theory Group and Laboratory of Biomolecular Research, Paul Scherrer Institut, Villigen PSI, Switzerland.

  • ↵2 Current affiliation: Boehringer Ingelheim Pharma GmbH and Co. KG, Biberach, Germany.

  1. K.S. and X.D. contributed equally to this work.

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Research ArticleArticle

A Structural Insight into the Reorientation of Transmembrane Domains 3 and 5 during Family A G Protein-Coupled Receptor Activation

Kamonchanok Sansuk, Xavier Deupi, Ivan R. Torrecillas, Aldo Jongejan, Saskia Nijmeijer, Remko A. Bakker, Leonardo Pardo and Rob Leurs
Molecular Pharmacology February 1, 2011, 79 (2) 262-269; DOI: https://doi.org/10.1124/mol.110.066068
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