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Molecular Pharmacology

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Table of Contents

April 01, 2011; Volume 79,Issue 4

Perspective

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    Paradoxical Stimulatory Effects of the “Standard” Histamine H4-Receptor Antagonist JNJ7777120: the H4 Receptor Joins the Club of 7 Transmembrane Domain Receptors Exhibiting Functional Selectivity
    Roland Seifert, Erich H. Schneider, Stefan Dove, Irena Brunskole, Detlef Neumann, Andrea Strasser and Armin Buschauer
    Molecular Pharmacology April 2011, 79 (4) 631-638; DOI: https://doi.org/10.1124/mol.111.071266

Articles

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    The High-Affinity cAMP-Specific Phosphodiesterase 8B Controls Steroidogenesis in the Mouse Adrenal Gland
    Li-Chun Lisa Tsai, Masami Shimizu-Albergine and Joseph A. Beavo
    Molecular Pharmacology April 2011, 79 (4) 639-648; DOI: https://doi.org/10.1124/mol.110.069104
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    Molecular Determinants of Potent P2X2 Antagonism Identified by Functional Analysis, Mutagenesis, and Homology Docking
    Christian Wolf, Christiane Rosefort, Ghada Fallah, Matthias U. Kassack, Alexandra Hamacher, Mandy Bodnar, Haihong Wang, Peter Illes, Achim Kless, Gregor Bahrenberg, Günther Schmalzing and Ralf Hausmann
    Molecular Pharmacology April 2011, 79 (4) 649-661; DOI: https://doi.org/10.1124/mol.110.068700
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    A State-Dependent Salt-Bridge Interaction Exists across the β/α Intersubunit Interface of the GABAA Receptor
    Kurt T. Laha and David A. Wagner
    Molecular Pharmacology April 2011, 79 (4) 662-671; DOI: https://doi.org/10.1124/mol.110.068619
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    The Tricyclic Antidepressant Amitriptyline Inhibits d-Cyclin Transactivation and Induces Myeloma Cell Apoptosis by Inhibiting Histone Deacetylases: In Vitro and In Silico Evidence
    Xinliang Mao, Tingjun Hou, Biyin Cao, Wenjie Wang, Zhihua Li, Suning Chen, Min Fei, Rose Hurren, Marcela Gronda, Depei Wu, Suzanne Trudel and Aaron D. Schimmer
    Molecular Pharmacology April 2011, 79 (4) 672-680; DOI: https://doi.org/10.1124/mol.110.068122
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    Why Does the Inner-Helix Mutation A413C Double the Stoichiometry of Kv1.3 Channel Block by Emopamil but Not by Verapamil?
    Alexey Rossokhin, Tobias Dreker, Stephan Grissmer and Boris S. Zhorov
    Molecular Pharmacology April 2011, 79 (4) 681-691; DOI: https://doi.org/10.1124/mol.110.068031
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    Coupling to Polymeric Scaffolds Stabilizes Biofunctional Peptides for Intracellular Applications
    Ivo R. Ruttekolk, Alokta Chakrabarti, Martin Richter, Falk Duchardt, Heike Glauner, Wouter P. R. Verdurmen, Jörg Rademann and Roland Brock
    Molecular Pharmacology April 2011, 79 (4) 692-700; DOI: https://doi.org/10.1124/mol.110.068296
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    Helix 8 of the M1 Muscarinic Acetylcholine Receptor: Scanning Mutagenesis Delineates a G Protein Recognition Site
    Robert G. Kaye, José W. Saldanha, Zhi-Liang Lu and Edward C. Hulme
    Molecular Pharmacology April 2011, 79 (4) 701-709; DOI: https://doi.org/10.1124/mol.110.070177
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    A Novel Defensive Mechanism against Acetaminophen Toxicity in the Mouse Lateral Nasal Gland: Role of CYP2A5-Mediated Regulation of Testosterone Homeostasis and Salivary Androgen-Binding Protein Expression
    Xin Zhou, Yuan Wei, Fang Xie, Christina M. Laukaitis, Robert C. Karn, Kerri Kluetzman, Jun Gu, Qing-Yu Zhang, Dean W. Roberts and Xinxin Ding
    Molecular Pharmacology April 2011, 79 (4) 710-723; DOI: https://doi.org/10.1124/mol.110.070045
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    Acute Disruption of Bone Marrow Hematopoiesis by Benzo(a)pyrene Is Selectively Reversed by Aryl Hydrocarbon Receptor-Mediated Processes
    Alhaji U. N′jai, Michele C. Larsen, Justin R. Bushkofsky, Charles J. Czuprynski and Colin R. Jefcoate
    Molecular Pharmacology April 2011, 79 (4) 724-734; DOI: https://doi.org/10.1124/mol.110.070631
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    Novel Regulation of Nuclear Factor-YB by miR-485-3p Affects the Expression of DNA Topoisomerase IIα and Drug Responsiveness
    Cheng-Fen Chen, Xiaolong He, Ahmet Dirim Arslan, Yin-Yuan Mo, William C. Reinhold, Yves Pommier and William T. Beck
    Molecular Pharmacology April 2011, 79 (4) 735-741; DOI: https://doi.org/10.1124/mol.110.069633
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    A Cation-π Interaction at a Phenylalanine Residue in the Glycine Receptor Binding Site Is Conserved for Different Agonists
    Stephan A. Pless, Ariele P. Hanek, Kerry L. Price, Joseph W. Lynch, Henry A. Lester, Dennis A. Dougherty and Sarah C. R. Lummis
    Molecular Pharmacology April 2011, 79 (4) 742-748; DOI: https://doi.org/10.1124/mol.110.069583
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    Agonist-Biased Signaling at the Histamine H4 Receptor: JNJ7777120 Recruits β-Arrestin without Activating G Proteins
    Elizabeth M. Rosethorne and Steven J. Charlton
    Molecular Pharmacology April 2011, 79 (4) 749-757; DOI: https://doi.org/10.1124/mol.110.068395
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    Effects of the Allosteric Antagonist 1-(4-Chlorophenyl)-3-[3-(6-pyrrolidin-1-ylpyridin-2-yl)phenyl]urea (PSNCBAM-1) on CB1 Receptor Modulation in the Cerebellum
    Xiaowei Wang, James G. Horswill, Benjamin J. Whalley and Gary J. Stephens
    Molecular Pharmacology April 2011, 79 (4) 758-767; DOI: https://doi.org/10.1124/mol.110.068197
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    Protein Kinase C-Mediated Phosphorylation of the μ-Opioid Receptor and Its Effects on Receptor Signaling
    Bo Feng, Zhihua Li and Jia Bei Wang
    Molecular Pharmacology April 2011, 79 (4) 768-775; DOI: https://doi.org/10.1124/mol.110.069096
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    The Penultimate Arginine of the Carboxyl Terminus Determines Slow Desensitization in a P2X Receptor from the Cattle Tick Boophilus microplus
    Selvan Bavan, Louise Farmer, Shire K. Singh, Volko A. Straub, Felix D. Guerrero and Steven J. Ennion
    Molecular Pharmacology April 2011, 79 (4) 776-785; DOI: https://doi.org/10.1124/mol.110.070037
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    Proinflammatory Stimuli Control N-Acylphosphatidylethanolamine-Specific Phospholipase D Expression in Macrophages
    Chenggang Zhu, Carlos Solorzano, Saurabh Sahar, Natalia Realini, Ernest Fung, Paolo Sassone-Corsi and Daniele Piomelli
    Molecular Pharmacology April 2011, 79 (4) 786-792; DOI: https://doi.org/10.1124/mol.110.070201

Erratum

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    Correction to “Antipsychotic Drugs Regulate Hedgehog Signaling by Modulation of 7-Dehydrocholesterol Reductase Levels”
    Molecular Pharmacology April 2011, 79 (4) 793; DOI: https://doi.org/10.1124/mol.79.4.793
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In this issue

Molecular Pharmacology: 79 (4)
Molecular Pharmacology
Vol. 79, Issue 4
1 Apr 2011
  • Table of Contents
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