Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Molecular Pharmacology
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Molecular Pharmacology

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit molpharm on Facebook
  • Follow molpharm on Twitter
  • Follow molpharm on LinkedIn
Research ArticleArticle

Why Does the Inner-Helix Mutation A413C Double the Stoichiometry of Kv1.3 Channel Block by Emopamil but Not by Verapamil?

Alexey Rossokhin, Tobias Dreker, Stephan Grissmer and Boris S. Zhorov
Molecular Pharmacology April 2011, 79 (4) 681-691; DOI: https://doi.org/10.1124/mol.110.068031
Alexey Rossokhin
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tobias Dreker
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Stephan Grissmer
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Boris S. Zhorov
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

vol. 79 no. 4 681-691
DOI 
https://doi.org/10.1124/mol.110.068031
PubMed 
21220411

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received August 5, 2010
  • Accepted January 10, 2011
  • Published online March 18, 2011.

Article Versions

  • Earlier version (January 10, 2011 - 04:58).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2011 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Alexey Rossokhin,
  2. Tobias Dreker,
  3. Stephan Grissmer and
  4. Boris S. Zhorov
  1. Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada (A.R., B.S.Z.); Research Centre of Neurology, Russian Academy of Medical Sciences, Moscow (A.R.); Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia (B.S.Z.); 4SC AG, Planegg-Martinsried, Germany (T.D.); and Institute of Applied Physiology, Ulm University, Ulm, Germany (S.G.)
  1. Address correspondence to:
    Dr. Boris S. Zhorov, Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada. E-mail: zhorov{at}mcmaster.ca
  1. A.R. and T.D. contributed equally to the study. S.G. and B.S.Z. should be considered co-senior authors.

View Full Text

Statistics from Altmetric.com

Article usage

Article usage: January 2011 to March 2023

AbstractFullPdf
Jan 2011196090
Feb 201138028
Mar 20112721438
Apr 2011239814
May 20116178
Jun 20113207
Jul 20114928
Aug 20112867
Sep 20112979
Oct 201128217
Nov 201139722
Dec 20111127
Jan 201226510
Feb 20121866
Mar 201257514
Apr 201226810
May 2012251321
Jun 201217715
Jul 201216410
Aug 201222510
Sep 20122278
Oct 2012331013
Nov 201224411
Dec 2012301112
Jan 2013361821
Feb 201312135
Mar 20132344
Apr 2013817
May 20131344
Jun 20131082
Jul 20131543
Aug 2013554
Sep 20132057
Oct 201315118
Nov 20139911
Dec 2013987
Jan 20142117
Feb 20141444
Mar 2014567
Apr 201413139
May 2014465
Jun 20141274
Jul 20141655
Aug 20141241
Sep 2014915
Oct 20142151
Nov 20141470
Dec 20141252
Jan 20151031
Feb 2015722
Mar 201510113
Apr 20151224
May 20152265
Jun 201521111
Jul 2015181311
Aug 20151394
Sep 20153265
Oct 2015840
Nov 2015382
Dec 2015601
Jan 20161238
Feb 2016812
Mar 201615211
Apr 20161511
May 2016723
Jun 20168107
Jul 201610518
Aug 201615614
Sep 20168414
Oct 2016162
Nov 20162115
Dec 20168113
Jan 20171104
Feb 2017090
Mar 20170122
Apr 2017360
May 2017643
Jun 2017281
Jul 20178202
Aug 2017721217
Sep 201725115
Oct 201711564
Nov 20171184
Dec 201701283
Jan 201844602
Feb 201842563
Mar 201832053
Apr 201811353
May 20180990
Jun 20180711
Jul 20182513
Aug 20181461
Sep 20181284
Oct 201805315
Nov 20180677
Dec 201842130
Jan 20195901
Feb 20192710
Mar 20192102
Apr 20191503
May 20191201
Jun 2019606
Jul 2019521
Aug 20191110
Sep 20191100
Oct 20191300
Nov 20191100
Dec 20192411
Jan 2020800
Feb 20201012
Mar 2020500
Apr 2020511
May 2020300
Jun 20201300
Jul 2020600
Aug 2020903
Sep 2020101
Oct 2020401
Nov 2020102
Dec 20201011
Jan 2021911
Feb 20211914
Mar 20211110
Apr 20211010
May 20211221
Jun 2021620
Jul 20211021
Aug 2021414
Sep 2021310
Oct 2021720
Nov 20211014
Dec 20212300
Jan 20221931
Feb 20221310
Mar 20221010
Apr 2022921
May 2022510
Jun 20221800
Jul 2022912
Aug 20221111
Sep 2022411
Oct 20221712
Nov 2022514
Dec 2022402
Jan 2023910
Feb 2023410
Mar 2023900

PreviousNext
Back to top

In this issue

Molecular Pharmacology: 79 (4)
Molecular Pharmacology
Vol. 79, Issue 4
1 Apr 2011
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Molecular Pharmacology article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Why Does the Inner-Helix Mutation A413C Double the Stoichiometry of Kv1.3 Channel Block by Emopamil but Not by Verapamil?
(Your Name) has forwarded a page to you from Molecular Pharmacology
(Your Name) thought you would be interested in this article in Molecular Pharmacology.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Research ArticleArticle

Why Does the Inner-Helix Mutation A413C Double the Stoichiometry of Kv1.3 Channel Block by Emopamil but Not by Verapamil?

Alexey Rossokhin, Tobias Dreker, Stephan Grissmer and Boris S. Zhorov
Molecular Pharmacology April 1, 2011, 79 (4) 681-691; DOI: https://doi.org/10.1124/mol.110.068031

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Research ArticleArticle

Why Does the Inner-Helix Mutation A413C Double the Stoichiometry of Kv1.3 Channel Block by Emopamil but Not by Verapamil?

Alexey Rossokhin, Tobias Dreker, Stephan Grissmer and Boris S. Zhorov
Molecular Pharmacology April 1, 2011, 79 (4) 681-691; DOI: https://doi.org/10.1124/mol.110.068031
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Authorship Contributions
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • Mechanism of the selective action of paraherquamide A
  • Fatty Acid Amide Hydrolase in Cisplatin Nephrotoxicity
  • Use-Dependent Relief of A-887826 Inhibition
Show more Articles

Similar Articles

Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About Molecular Pharmacology
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Journal of Pharmacology and Experimental Therapeutics
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0111 (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics