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Research ArticleArticle

A Novel Defensive Mechanism against Acetaminophen Toxicity in the Mouse Lateral Nasal Gland: Role of CYP2A5-Mediated Regulation of Testosterone Homeostasis and Salivary Androgen-Binding Protein Expression

Xin Zhou, Yuan Wei, Fang Xie, Christina M. Laukaitis, Robert C. Karn, Kerri Kluetzman, Jun Gu, Qing-Yu Zhang, Dean W. Roberts and Xinxin Ding
Molecular Pharmacology April 2011, 79 (4) 710-723; DOI: https://doi.org/10.1124/mol.110.070045

Article Information

vol. 79 no. 4 710-723
DOI 
https://doi.org/10.1124/mol.110.070045
PubMed 
21252290
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received November 16, 2010
  • Accepted January 19, 2011
  • Published online March 18, 2011.

Article Versions

Copyright & Usage 
Copyright © 2011 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Xin Zhou,
  2. Yuan Wei,
  3. Fang Xie,
  4. Christina M. Laukaitis,
  5. Robert C. Karn,
  6. Kerri Kluetzman,
  7. Jun Gu,
  8. Qing-Yu Zhang,
  9. Dean W. Roberts and
  10. Xinxin Ding
  1. Wadsworth Center, New York State Department of Health, and School of Public Health, State University of New York at Albany, Albany, New York (X.Z, Y.W., F.X., K.K., J.G., Q.-Y.Z., X.D.); College of Medicine, University of Arizona, Tucson, Arizona (C.M.L., R.C.K.); and Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, Arkansas (D.W.R.)
  1. Address correspondence to:
    Dr. Xinxin Ding, Wadsworth Center, New York State Department of Health, Empire State Plaza, Box 509, Albany, NY 12201-0509. E-mail: xding{at}wadsworth.org
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Research ArticleArticle

A Novel Defensive Mechanism against Acetaminophen Toxicity in the Mouse Lateral Nasal Gland: Role of CYP2A5-Mediated Regulation of Testosterone Homeostasis and Salivary Androgen-Binding Protein Expression

Xin Zhou, Yuan Wei, Fang Xie, Christina M. Laukaitis, Robert C. Karn, Kerri Kluetzman, Jun Gu, Qing-Yu Zhang, Dean W. Roberts and Xinxin Ding
Molecular Pharmacology April 1, 2011, 79 (4) 710-723; DOI: https://doi.org/10.1124/mol.110.070045
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