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Research ArticleArticle

The Role of Transmembrane Domain 3 in the Actions of Orthosteric, Allosteric, and Atypical Agonists of the M4 Muscarinic Acetylcholine Receptor

Katie Leach, Anna E. Davey, Christian C. Felder, Patrick M. Sexton and Arthur Christopoulos
Molecular Pharmacology May 2011, 79 (5) 855-865; DOI: https://doi.org/10.1124/mol.111.070938

Article Information

vol. 79 no. 5 855-865
DOI 
https://doi.org/10.1124/mol.111.070938
PubMed 
21300722
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received January 2, 2011
  • Accepted February 7, 2011
  • Published online April 19, 2011.

Article Versions

Copyright & Usage 
Copyright © 2011 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Katie Leach,
  2. Anna E. Davey,
  3. Christian C. Felder,
  4. Patrick M. Sexton and
  5. Arthur Christopoulos
  1. Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences and Department of Pharmacology, Monash University, Parkville, Victoria, Australia (K.L., A.E.D., P.M.S., A.C.); and Eli Lilly and Co., Indianapolis, Indiana (C.C.F.)
  1. Address correspondence to:
    Dr. Arthur Christopoulos, Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Parkville, 3052, Victoria, Australia. E-mail: arthur.christopoulos{at}monash.edu
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Research ArticleArticle

The Role of Transmembrane Domain 3 in the Actions of Orthosteric, Allosteric, and Atypical Agonists of the M4 Muscarinic Acetylcholine Receptor

Katie Leach, Anna E. Davey, Christian C. Felder, Patrick M. Sexton and Arthur Christopoulos
Molecular Pharmacology May 1, 2011, 79 (5) 855-865; DOI: https://doi.org/10.1124/mol.111.070938
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