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Research ArticleArticle

Quantitative Analysis Reveals Multiple Mechanisms of Allosteric Modulation of the mGlu5 Receptor in Rat Astroglia

Sophie J. Bradley, Christopher J. Langmead, Jeannette M. Watson and R. A. John Challiss
Molecular Pharmacology May 2011, 79 (5) 874-885; DOI: https://doi.org/10.1124/mol.110.068882

Article Information

vol. 79 no. 5 874-885
DOI 
https://doi.org/10.1124/mol.110.068882
PubMed 
21321061
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received September 13, 2010
  • Accepted February 1, 2011
  • Published online April 19, 2011.

Article Versions

Copyright & Usage 
Copyright © 2011 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Sophie J. Bradley,
  2. Christopher J. Langmead,
  3. Jeannette M. Watson and
  4. R. A. John Challiss
  1. Department of Cell Physiology and Pharmacology, University of Leicester, Leicester, United Kingdom (S.J.B., R.A.J.C.); Heptares Therapeutics Ltd., Welwyn Garden City, United Kingdom (C.J.L.); and Neuroscience Centre of Excellence in Drug Discovery, GlaxoSmithKline, Harlow, United Kingdom (J.M.W.)
  1. Address correspondence to:
    Dr. R. A. J. Challiss, Department of Cell Physiology and Pharmacology, University of Leicester, Room 4/04, Henry Wellcome Building, Lancaster Road, Leicester, LE1 9HN, United Kingdom. E-mail: jc36{at}leicester.ac.uk
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Research ArticleArticle

Quantitative Analysis Reveals Multiple Mechanisms of Allosteric Modulation of the mGlu5 Receptor in Rat Astroglia

Sophie J. Bradley, Christopher J. Langmead, Jeannette M. Watson and R. A. John Challiss
Molecular Pharmacology May 1, 2011, 79 (5) 874-885; DOI: https://doi.org/10.1124/mol.110.068882
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