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Research ArticleArticle

Pharmacological Characterization of 1-(5-Chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic Acid (JNJ-42041935), a Potent and Selective Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor

Terrance D. Barrett, Heather L. Palomino, Theresa I. Brondstetter, Kimon C. Kanelakis, Xiaodong Wu, Peter V. Haug, Wen Yan, Andrew Young, Hong Hua, Juliet C. Hart, Da-Thao Tran, Hariharan Venkatesan, Mark D. Rosen, Hillary M. Peltier, Kia Sepassi, Michele C. Rizzolio, Scott D. Bembenek, Tara Mirzadegan, Michael H. Rabinowitz and Nigel P. Shankley
Molecular Pharmacology June 2011, 79 (6) 910-920; DOI: https://doi.org/10.1124/mol.110.070508

Article Information

vol. 79 no. 6 910-920
DOI 
https://doi.org/10.1124/mol.110.070508
PubMed 
21372172
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received December 10, 2010
  • Accepted March 3, 2011
  • Published online May 17, 2011.

Article Versions

Copyright & Usage 
Copyright © 2011 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Terrance D. Barrett,
  2. Heather L. Palomino,
  3. Theresa I. Brondstetter,
  4. Kimon C. Kanelakis,
  5. Xiaodong Wu,
  6. Peter V. Haug,
  7. Wen Yan,
  8. Andrew Young,
  9. Hong Hua,
  10. Juliet C. Hart,
  11. Da-Thao Tran,
  12. Hariharan Venkatesan,
  13. Mark D. Rosen,
  14. Hillary M. Peltier,
  15. Kia Sepassi,
  16. Michele C. Rizzolio,
  17. Scott D. Bembenek,
  18. Tara Mirzadegan,
  19. Michael H. Rabinowitz and
  20. Nigel P. Shankley
  1. Cardiovascular Metabolic Team, Johnson & Johnson Pharmaceutical Research and Development, LLC, San Diego, California
  1. Address correspondence to:
    Dr. Terrance D. Barrett, Cardiovascular Metabolic Research, Johnson and Johnson Pharmaceutical Research and Development LLC, 3210 Merryfield Row, San Diego, CA 92121. E-mail: tbarret1{at}its.jnj.com
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Research ArticleArticle

Pharmacological Characterization of 1-(5-Chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic Acid (JNJ-42041935), a Potent and Selective Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor

Terrance D. Barrett, Heather L. Palomino, Theresa I. Brondstetter, Kimon C. Kanelakis, Xiaodong Wu, Peter V. Haug, Wen Yan, Andrew Young, Hong Hua, Juliet C. Hart, Da-Thao Tran, Hariharan Venkatesan, Mark D. Rosen, Hillary M. Peltier, Kia Sepassi, Michele C. Rizzolio, Scott D. Bembenek, Tara Mirzadegan, Michael H. Rabinowitz and Nigel P. Shankley
Molecular Pharmacology June 1, 2011, 79 (6) 910-920; DOI: https://doi.org/10.1124/mol.110.070508
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