Cannabidiol and Other Cannabinoids Reduce Microglial Activation In Vitro and In Vivo: Relevance to Alzheimer's Disease

Neurodegeneration Group, Department of Cellular, Molecular and Developmental Neurobiology, Instituto Cajal, Consejo Superior de Investigaciones Cientificas, Madrid, Spain (A.M.M.-M., D.R., B.G.R., M.L.C.); Centro de Investigación en Red en Enfermedades Neurodegenerativas (A.M.M.-M., D.R., B.G.R., M.L.C., N.I., A.C.) and Institute for Drug Research, Medical Faculty, Hebrew University (R.M.), Jerusalem, Israel; and Departamento de Bioquímica, Instituto de Investigaciones Biomédicas “Alberto Sols” UAM-Consejo Superior de Investigaciones Cientificas, Facultad de Medicina, Universidad Autónoma de Madrid, Madrid, Spain (N.I., A.C.)

Address correspondence to:
Dr. M. L. de Ceballos, Neurodegeneration Group, Department of Cellular, Molecular and Developmental Neurobiology, Instituto Cajal, CSIC, Doctor Arce, 37, 28002 Madrid, Spain. E-mail: mceballos{at}cajal.csic.es

A.M.M.-M. and D.R. contributed equally to this work.

↵¹ Current affiliation: Molecular Neuroprotection Group, Experimental Neurology Unit, Paraplejic National Hospital, Toledo, Spain.
↵² Current affiliation: Unidad de Apoyo a la Investigación, Fundación MD Anderson Internacional España, Madrid, Spain.

View Full Text

Statistics from Altmetric.com

Article usage

Article usage: February 2011 to June 2021

	Abstract	Full	Pdf
Feb 2011	111	0	204
Mar 2011	191	0	662
Apr 2011	120	0	318
May 2011	334	27	210
Jun 2011	312	45	111
Jul 2011	117	22	104
Aug 2011	96	41	72
Sep 2011	89	28	90
Oct 2011	75	46	76
Nov 2011	67	31	91
Dec 2011	53	28	63
Jan 2012	81	24	77
Feb 2012	55	16	89
Mar 2012	90	19	75
Apr 2012	62	17	92
May 2012	61	32	78
Jun 2012	51	29	52
Jul 2012	37	41	64
Aug 2012	31	30	50
Sep 2012	31	25	61
Oct 2012	44	44	68
Nov 2012	76	55	82
Dec 2012	39	22	67
Jan 2013	57	42	62
Feb 2013	56	31	61
Mar 2013	62	32	71
Apr 2013	45	43	69
May 2013	43	33	68
Jun 2013	31	27	17
Jul 2013	37	43	54
Aug 2013	21	25	56
Sep 2013	47	29	41
Oct 2013	32	29	40
Nov 2013	33	30	55
Dec 2013	48	37	56
Jan 2014	32	36	84
Feb 2014	49	25	58
Mar 2014	48	36	58
Apr 2014	35	33	43
May 2014	36	26	66
Jun 2014	47	27	104
Jul 2014	63	19	47
Aug 2014	24	49	43
Sep 2014	37	32	37
Oct 2014	65	48	51
Nov 2014	46	57	64
Dec 2014	37	39	46
Jan 2015	72	18	44
Feb 2015	39	43	32
Mar 2015	37	31	40
Apr 2015	53	38	47
May 2015	56	26	44
Jun 2015	26	26	34
Jul 2015	42	26	74
Aug 2015	60	30	27
Sep 2015	50	20	28
Oct 2015	43	23	44
Nov 2015	46	29	31
Dec 2015	33	22	36
Jan 2016	45	20	38
Feb 2016	15	27	25
Mar 2016	30	17	26
Apr 2016	21	63	40
May 2016	30	18	37
Jun 2016	17	9	29
Jul 2016	44	20	29
Aug 2016	16	17	36
Sep 2016	28	28	37
Oct 2016	24	25	26
Nov 2016	27	57	29
Dec 2016	30	41	6
Jan 2017	49	46	29
Feb 2017	50	44	19
Mar 2017	45	58	26
Apr 2017	41	40	16
May 2017	58	43	29
Jun 2017	54	52	41
Jul 2017	36	34	17
Aug 2017	34	53	12
Sep 2017	87	38	22
Oct 2017	59	61	17
Nov 2017	66	117	64
Dec 2017	33	208	21
Jan 2018	68	200	39
Feb 2018	67	72	30
Mar 2018	58	160	49
Apr 2018	46	141	45
May 2018	64	138	57
Jun 2018	172	134	37
Jul 2018	41	105	36
Aug 2018	79	184	42
Sep 2018	55	197	51
Oct 2018	65	214	60
Nov 2018	54	206	53
Dec 2018	203	45	22
Jan 2019	232	10	19
Feb 2019	233	13	22
Mar 2019	253	7	25
Apr 2019	227	6	17
May 2019	201	4	20
Jun 2019	205	2	18
Jul 2019	214	9	15
Aug 2019	198	7	63
Sep 2019	225	11	31
Oct 2019	245	8	126
Nov 2019	235	3	162
Dec 2019	205	4	205
Jan 2020	239	17	178
Feb 2020	269	17	12
Mar 2020	331	15	13
Apr 2020	350	1	7
May 2020	396	12	12
Jun 2020	236	8	5
Jul 2020	213	8	5
Aug 2020	216	10	19
Sep 2020	213	36	42
Oct 2020	289	43	45
Nov 2020	289	34	25
Dec 2020	246	30	27
Jan 2021	206	15	20
Feb 2021	234	18	16
Mar 2021	299	25	17
Apr 2021	339	11	18
May 2021	304	17	16
Jun 2021	120	11	11