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Index by author

December 01, 2011; Volume 80,Issue 6

A

  1. Abdel-Halim, Heba

    1. 2-Aminoethyl Methylphosphonate, a Potent and Rapidly Acting Antagonist of GABAA-ρ1 Receptors
      An Xie, Jun Yan, Lan Yue, Feng Feng, Fozia Mir, Heba Abdel-Halim, Mary Chebib, Guy C. Le Breton, Robert F. Standaert, Haohua Qian and David R. Pepperberg
      Molecular Pharmacology December 2011, 80 (6) 965-978; DOI: https://doi.org/10.1124/mol.111.071225

  2. Adcock, Ian M.

    1. p38 Mitogen-Activated Protein Kinase-γ Inhibition by Long-Acting β2 Adrenergic Agonists Reversed Steroid Insensitivity in Severe Asthma
      Nicholas Mercado, Yasuo To, Yoshiki Kobayashi, Ian M. Adcock, Peter J. Barnes and Kazuhiro Ito
      Molecular Pharmacology December 2011, 80 (6) 1128-1135; DOI: https://doi.org/10.1124/mol.111.071993

  3. Alvarez-Curto, Elisa

    1. Developing Chemical Genetic Approaches to Explore G Protein-Coupled Receptor Function: Validation of the Use of a Receptor Activated Solely by Synthetic Ligand (RASSL)
      Elisa Alvarez-Curto, Rudi Prihandoko, Christofer S. Tautermann, Jurriaan M. Zwier, John D. Pediani, Martin J. Lohse, Carsten Hoffmann, Andrew B. Tobin and Graeme Milligan
      Molecular Pharmacology December 2011, 80 (6) 1033-1046; DOI: https://doi.org/10.1124/mol.111.074674

  4. Auld, Douglas S.

    1. Identification of a Novel Allosteric Binding Site in the CXCR2 Chemokine Receptor
      Petra de Kruijf, Herman D. Lim, Luc Roumen, Véronique A. Renjaän, Jiuqiao Zhao, Maria L. Webb, Douglas S. Auld, Jac. C.H.M. Wijkmans, Guido J. R. Zaman, Martine J. Smit, Chris de Graaf and Rob Leurs
      Molecular Pharmacology December 2011, 80 (6) 1108-1118; DOI: https://doi.org/10.1124/mol.111.073825

B

  1. Barnes, Peter J.

    1. p38 Mitogen-Activated Protein Kinase-γ Inhibition by Long-Acting β2 Adrenergic Agonists Reversed Steroid Insensitivity in Severe Asthma
      Nicholas Mercado, Yasuo To, Yoshiki Kobayashi, Ian M. Adcock, Peter J. Barnes and Kazuhiro Ito
      Molecular Pharmacology December 2011, 80 (6) 1128-1135; DOI: https://doi.org/10.1124/mol.111.071993

  2. Belcourt, Michael F.

    1. Reduced Level of Ribonucleotide Reductase R2 Subunits Increases Dependence on Homologous Recombination Repair of Cisplatin-Induced DNA Damage
      Z. Ping Lin, Yashang Lee, Fang Lin, Michael F. Belcourt, Peining Li, Joseph G. Cory, Peter M. Glazer and Alan C. Sartorelli
      Molecular Pharmacology December 2011, 80 (6) 1000-1012; DOI: https://doi.org/10.1124/mol.111.074708

  3. Berger, Joel P.

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

  4. Bian, Ka

    1. Restoring Soluble Guanylyl Cyclase Expression and Function Blocks the Aggressive Course of Glioma
      Haifeng Zhu, Jessica Tao Li, Fang Zheng, Emil Martin, Alexander Y. Kots, Joshua S. Krumenacker, Byung-Kwon Choi, Ian E. McCutcheon, Norman Weisbrodt, Oliver Bögler, Ferid Murad and Ka Bian
      Molecular Pharmacology December 2011, 80 (6) 1076-1084; DOI: https://doi.org/10.1124/mol.111.073585

  5. Bigagli, Elisabetta

    1. Pharmacological Effects of Exogenous NAD on Mitochondrial Bioenergetics, DNA Repair, and Apoptosis
      Maria Pittelli, Roberta Felici, Vanessa Pitozzi, Lisa Giovannelli, Elisabetta Bigagli, Francesca Cialdai, Giovanni Romano, Flavio Moroni and Alberto Chiarugi
      Molecular Pharmacology December 2011, 80 (6) 1136-1146; DOI: https://doi.org/10.1124/mol.111.073916

  6. Bögler, Oliver

    1. Restoring Soluble Guanylyl Cyclase Expression and Function Blocks the Aggressive Course of Glioma
      Haifeng Zhu, Jessica Tao Li, Fang Zheng, Emil Martin, Alexander Y. Kots, Joshua S. Krumenacker, Byung-Kwon Choi, Ian E. McCutcheon, Norman Weisbrodt, Oliver Bögler, Ferid Murad and Ka Bian
      Molecular Pharmacology December 2011, 80 (6) 1076-1084; DOI: https://doi.org/10.1124/mol.111.073585

  7. Brim, Remy L.

    1. The Ability of Bacterial Cocaine Esterase to Hydrolyze Cocaine Metabolites and Their Simultaneous Quantification Using High-Performance Liquid Chromatography-Tandem Mass Spectrometry
      Remy L. Brim, Kathleen R. Noon, Gregory T. Collins, Joseph Nichols, Diwahar Narasimhan, Roger K. Sunahara and James H. Woods
      Molecular Pharmacology December 2011, 80 (6) 1119-1127; DOI: https://doi.org/10.1124/mol.111.074534

C

  1. Chan, Jimmy

    1. Subunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence Time
      Diwahar Narasimhan, Gregory T. Collins, Mark R. Nance, Joseph Nichols, Elin Edwald, Jimmy Chan, Mei-Chuan Ko, James H. Woods, John J. G. Tesmer and Roger K. Sunahara
      Molecular Pharmacology December 2011, 80 (6) 1056-1065; DOI: https://doi.org/10.1124/mol.111.074997

  2. Chebib, Mary

    1. 2-Aminoethyl Methylphosphonate, a Potent and Rapidly Acting Antagonist of GABAA-ρ1 Receptors
      An Xie, Jun Yan, Lan Yue, Feng Feng, Fozia Mir, Heba Abdel-Halim, Mary Chebib, Guy C. Le Breton, Robert F. Standaert, Haohua Qian and David R. Pepperberg
      Molecular Pharmacology December 2011, 80 (6) 965-978; DOI: https://doi.org/10.1124/mol.111.071225

  3. Cherian, Christina

    1. Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Eric Hales, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology December 2011, 80 (6) 1096-1107; DOI: https://doi.org/10.1124/mol.111.073833

  4. Chiarugi, Alberto

    1. Pharmacological Effects of Exogenous NAD on Mitochondrial Bioenergetics, DNA Repair, and Apoptosis
      Maria Pittelli, Roberta Felici, Vanessa Pitozzi, Lisa Giovannelli, Elisabetta Bigagli, Francesca Cialdai, Giovanni Romano, Flavio Moroni and Alberto Chiarugi
      Molecular Pharmacology December 2011, 80 (6) 1136-1146; DOI: https://doi.org/10.1124/mol.111.073916

  5. Chiba, Masato

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

  6. Choi, Byung-Kwon

    1. Restoring Soluble Guanylyl Cyclase Expression and Function Blocks the Aggressive Course of Glioma
      Haifeng Zhu, Jessica Tao Li, Fang Zheng, Emil Martin, Alexander Y. Kots, Joshua S. Krumenacker, Byung-Kwon Choi, Ian E. McCutcheon, Norman Weisbrodt, Oliver Bögler, Ferid Murad and Ka Bian
      Molecular Pharmacology December 2011, 80 (6) 1076-1084; DOI: https://doi.org/10.1124/mol.111.073585

  7. Choi, Mihwa

    1. Dynamic and Ligand-Selective Interactions of Vitamin D Receptor with Retinoid X Receptor and Cofactors in Living Cells
      Mihwa Choi, Sachiko Yamada and Makoto Makishima
      Molecular Pharmacology December 2011, 80 (6) 1147-1155; DOI: https://doi.org/10.1124/mol.111.074138

  8. Cialdai, Francesca

    1. Pharmacological Effects of Exogenous NAD on Mitochondrial Bioenergetics, DNA Repair, and Apoptosis
      Maria Pittelli, Roberta Felici, Vanessa Pitozzi, Lisa Giovannelli, Elisabetta Bigagli, Francesca Cialdai, Giovanni Romano, Flavio Moroni and Alberto Chiarugi
      Molecular Pharmacology December 2011, 80 (6) 1136-1146; DOI: https://doi.org/10.1124/mol.111.073916

  9. Codogno, Patrice

    1. Ca2+/Calmodulin-Dependent Kinase (CaMK) Signaling via CaMKI and AMP-Activated Protein Kinase Contributes to the Regulation of WIPI-1 at the Onset of Autophagy
      Simon G. Pfisterer, Mario Mauthe, Patrice Codogno and Tassula Proikas-Cezanne
      Molecular Pharmacology December 2011, 80 (6) 1066-1075; DOI: https://doi.org/10.1124/mol.111.071761

  10. Collins, Gregory T.

    1. The Ability of Bacterial Cocaine Esterase to Hydrolyze Cocaine Metabolites and Their Simultaneous Quantification Using High-Performance Liquid Chromatography-Tandem Mass Spectrometry
      Remy L. Brim, Kathleen R. Noon, Gregory T. Collins, Joseph Nichols, Diwahar Narasimhan, Roger K. Sunahara and James H. Woods
      Molecular Pharmacology December 2011, 80 (6) 1119-1127; DOI: https://doi.org/10.1124/mol.111.074534
    2. Subunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence Time
      Diwahar Narasimhan, Gregory T. Collins, Mark R. Nance, Joseph Nichols, Elin Edwald, Jimmy Chan, Mei-Chuan Ko, James H. Woods, John J. G. Tesmer and Roger K. Sunahara
      Molecular Pharmacology December 2011, 80 (6) 1056-1065; DOI: https://doi.org/10.1124/mol.111.074997

  11. Cory, Joseph G.

    1. Reduced Level of Ribonucleotide Reductase R2 Subunits Increases Dependence on Homologous Recombination Repair of Cisplatin-Induced DNA Damage
      Z. Ping Lin, Yashang Lee, Fang Lin, Michael F. Belcourt, Peining Li, Joseph G. Cory, Peter M. Glazer and Alan C. Sartorelli
      Molecular Pharmacology December 2011, 80 (6) 1000-1012; DOI: https://doi.org/10.1124/mol.111.074708

D

  1. de Graaf, Chris

    1. Identification of a Novel Allosteric Binding Site in the CXCR2 Chemokine Receptor
      Petra de Kruijf, Herman D. Lim, Luc Roumen, Véronique A. Renjaän, Jiuqiao Zhao, Maria L. Webb, Douglas S. Auld, Jac. C.H.M. Wijkmans, Guido J. R. Zaman, Martine J. Smit, Chris de Graaf and Rob Leurs
      Molecular Pharmacology December 2011, 80 (6) 1108-1118; DOI: https://doi.org/10.1124/mol.111.073825

  2. de Kruijf, Petra

    1. Identification of a Novel Allosteric Binding Site in the CXCR2 Chemokine Receptor
      Petra de Kruijf, Herman D. Lim, Luc Roumen, Véronique A. Renjaän, Jiuqiao Zhao, Maria L. Webb, Douglas S. Auld, Jac. C.H.M. Wijkmans, Guido J. R. Zaman, Martine J. Smit, Chris de Graaf and Rob Leurs
      Molecular Pharmacology December 2011, 80 (6) 1108-1118; DOI: https://doi.org/10.1124/mol.111.073825

  3. Deng, Qiaolin

    1. Identification of Novel and Selective KV2 Channel Inhibitors
      James Herrington, Kelli Solly, Kevin S. Ratliff, Nina Li, Yun-Ping Zhou, Andrew Howard, Laszlo Kiss, Maria L. Garcia, Owen B. McManus, Qiaolin Deng, Ranjit Desai, Yusheng Xiong and Gregory J. Kaczorowski
      Molecular Pharmacology December 2011, 80 (6) 959-964; DOI: https://doi.org/10.1124/mol.111.074831

  4. Desai, Ranjit

    1. Identification of Novel and Selective KV2 Channel Inhibitors
      James Herrington, Kelli Solly, Kevin S. Ratliff, Nina Li, Yun-Ping Zhou, Andrew Howard, Laszlo Kiss, Maria L. Garcia, Owen B. McManus, Qiaolin Deng, Ranjit Desai, Yusheng Xiong and Gregory J. Kaczorowski
      Molecular Pharmacology December 2011, 80 (6) 959-964; DOI: https://doi.org/10.1124/mol.111.074831

E

  1. Edwald, Elin

    1. Subunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence Time
      Diwahar Narasimhan, Gregory T. Collins, Mark R. Nance, Joseph Nichols, Elin Edwald, Jimmy Chan, Mei-Chuan Ko, James H. Woods, John J. G. Tesmer and Roger K. Sunahara
      Molecular Pharmacology December 2011, 80 (6) 1056-1065; DOI: https://doi.org/10.1124/mol.111.074997

  2. Eiki, Jun-ichi

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

F

  1. Felici, Roberta

    1. Pharmacological Effects of Exogenous NAD on Mitochondrial Bioenergetics, DNA Repair, and Apoptosis
      Maria Pittelli, Roberta Felici, Vanessa Pitozzi, Lisa Giovannelli, Elisabetta Bigagli, Francesca Cialdai, Giovanni Romano, Flavio Moroni and Alberto Chiarugi
      Molecular Pharmacology December 2011, 80 (6) 1136-1146; DOI: https://doi.org/10.1124/mol.111.073916

  2. Feng, Feng

    1. 2-Aminoethyl Methylphosphonate, a Potent and Rapidly Acting Antagonist of GABAA-ρ1 Receptors
      An Xie, Jun Yan, Lan Yue, Feng Feng, Fozia Mir, Heba Abdel-Halim, Mary Chebib, Guy C. Le Breton, Robert F. Standaert, Haohua Qian and David R. Pepperberg
      Molecular Pharmacology December 2011, 80 (6) 965-978; DOI: https://doi.org/10.1124/mol.111.071225

  3. Fujii, Kenji

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

  4. Futamura, Mayumi

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

G

  1. Gangjee, Aleem

    1. Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Eric Hales, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology December 2011, 80 (6) 1096-1107; DOI: https://doi.org/10.1124/mol.111.073833

  2. Garcia, Maria L.

    1. Identification of Novel and Selective KV2 Channel Inhibitors
      James Herrington, Kelli Solly, Kevin S. Ratliff, Nina Li, Yun-Ping Zhou, Andrew Howard, Laszlo Kiss, Maria L. Garcia, Owen B. McManus, Qiaolin Deng, Ranjit Desai, Yusheng Xiong and Gregory J. Kaczorowski
      Molecular Pharmacology December 2011, 80 (6) 959-964; DOI: https://doi.org/10.1124/mol.111.074831

  3. Giovannelli, Lisa

    1. Pharmacological Effects of Exogenous NAD on Mitochondrial Bioenergetics, DNA Repair, and Apoptosis
      Maria Pittelli, Roberta Felici, Vanessa Pitozzi, Lisa Giovannelli, Elisabetta Bigagli, Francesca Cialdai, Giovanni Romano, Flavio Moroni and Alberto Chiarugi
      Molecular Pharmacology December 2011, 80 (6) 1136-1146; DOI: https://doi.org/10.1124/mol.111.073916

  4. Glazer, Peter M.

    1. Reduced Level of Ribonucleotide Reductase R2 Subunits Increases Dependence on Homologous Recombination Repair of Cisplatin-Induced DNA Damage
      Z. Ping Lin, Yashang Lee, Fang Lin, Michael F. Belcourt, Peining Li, Joseph G. Cory, Peter M. Glazer and Alan C. Sartorelli
      Molecular Pharmacology December 2011, 80 (6) 1000-1012; DOI: https://doi.org/10.1124/mol.111.074708

  5. Goto-Shimazaki, Hiroko

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

H

  1. Hales, Eric

    1. Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Eric Hales, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology December 2011, 80 (6) 1096-1107; DOI: https://doi.org/10.1124/mol.111.073833

  2. Halpert, James R.

    1. Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains
      Manish B. Shah, Jaime Pascual, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology December 2011, 80 (6) 1047-1055; DOI: https://doi.org/10.1124/mol.111.074427

  3. Henderson, George I.

    1. Overexpression of Nrf2 Protects Cerebral Cortical Neurons from Ethanol-Induced Apoptotic Death
      Madhusudhanan Narasimhan, Lenin Mahimainathan, Mary Latha Rathinam, Amanjot Kaur Riar and George I. Henderson
      Molecular Pharmacology December 2011, 80 (6) 988-999; DOI: https://doi.org/10.1124/mol.111.073262

  4. Herrington, James

    1. Identification of Novel and Selective KV2 Channel Inhibitors
      James Herrington, Kelli Solly, Kevin S. Ratliff, Nina Li, Yun-Ping Zhou, Andrew Howard, Laszlo Kiss, Maria L. Garcia, Owen B. McManus, Qiaolin Deng, Ranjit Desai, Yusheng Xiong and Gregory J. Kaczorowski
      Molecular Pharmacology December 2011, 80 (6) 959-964; DOI: https://doi.org/10.1124/mol.111.074831

  5. Hien, Tran Thi

    1. Nectandrin B Activates Endothelial Nitric-Oxide Synthase Phosphorylation in Endothelial Cells: Role of the AMP-Activated Protein Kinase/Estrogen Receptor α/Phosphatidylinositol 3-kinase/Akt Pathway
      Tran Thi Hien, Won Keun Oh, Phi Hung Nguyen, Seok Jeong Oh, Moo Yeol Lee and Keon Wook Kang
      Molecular Pharmacology December 2011, 80 (6) 1166-1178; DOI: https://doi.org/10.1124/mol.111.073502

  6. Hoffmann, Carsten

    1. Developing Chemical Genetic Approaches to Explore G Protein-Coupled Receptor Function: Validation of the Use of a Receptor Activated Solely by Synthetic Ligand (RASSL)
      Elisa Alvarez-Curto, Rudi Prihandoko, Christofer S. Tautermann, Jurriaan M. Zwier, John D. Pediani, Martin J. Lohse, Carsten Hoffmann, Andrew B. Tobin and Graeme Milligan
      Molecular Pharmacology December 2011, 80 (6) 1033-1046; DOI: https://doi.org/10.1124/mol.111.074674

  7. Hosaka, Hideka

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

  8. Hou, Zhanjun

    1. Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Eric Hales, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology December 2011, 80 (6) 1096-1107; DOI: https://doi.org/10.1124/mol.111.073833

  9. Howard, Andrew

    1. Identification of Novel and Selective KV2 Channel Inhibitors
      James Herrington, Kelli Solly, Kevin S. Ratliff, Nina Li, Yun-Ping Zhou, Andrew Howard, Laszlo Kiss, Maria L. Garcia, Owen B. McManus, Qiaolin Deng, Ranjit Desai, Yusheng Xiong and Gregory J. Kaczorowski
      Molecular Pharmacology December 2011, 80 (6) 959-964; DOI: https://doi.org/10.1124/mol.111.074831

I

  1. Iino, Tomoharu

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

  2. Ito, Kazuhiro

    1. p38 Mitogen-Activated Protein Kinase-γ Inhibition by Long-Acting β2 Adrenergic Agonists Reversed Steroid Insensitivity in Severe Asthma
      Nicholas Mercado, Yasuo To, Yoshiki Kobayashi, Ian M. Adcock, Peter J. Barnes and Kazuhiro Ito
      Molecular Pharmacology December 2011, 80 (6) 1128-1135; DOI: https://doi.org/10.1124/mol.111.071993

K

  1. Kaczorowski, Gregory J.

    1. Identification of Novel and Selective KV2 Channel Inhibitors
      James Herrington, Kelli Solly, Kevin S. Ratliff, Nina Li, Yun-Ping Zhou, Andrew Howard, Laszlo Kiss, Maria L. Garcia, Owen B. McManus, Qiaolin Deng, Ranjit Desai, Yusheng Xiong and Gregory J. Kaczorowski
      Molecular Pharmacology December 2011, 80 (6) 959-964; DOI: https://doi.org/10.1124/mol.111.074831

  2. Kadotani, Akito

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

  3. Kalia, Jeet

    1. Elucidating the Molecular Basis of Action of a Classic Drug: Guanidine Compounds As Inhibitors of Voltage-Gated Potassium Channels
      Jeet Kalia and Kenton J. Swartz
      Molecular Pharmacology December 2011, 80 (6) 1085-1095; DOI: https://doi.org/10.1124/mol.111.074989

  4. Kang, Keon Wook

    1. Nectandrin B Activates Endothelial Nitric-Oxide Synthase Phosphorylation in Endothelial Cells: Role of the AMP-Activated Protein Kinase/Estrogen Receptor α/Phosphatidylinositol 3-kinase/Akt Pathway
      Tran Thi Hien, Won Keun Oh, Phi Hung Nguyen, Seok Jeong Oh, Moo Yeol Lee and Keon Wook Kang
      Molecular Pharmacology December 2011, 80 (6) 1166-1178; DOI: https://doi.org/10.1124/mol.111.073502

  5. Kiss, Laszlo

    1. Identification of Novel and Selective KV2 Channel Inhibitors
      James Herrington, Kelli Solly, Kevin S. Ratliff, Nina Li, Yun-Ping Zhou, Andrew Howard, Laszlo Kiss, Maria L. Garcia, Owen B. McManus, Qiaolin Deng, Ranjit Desai, Yusheng Xiong and Gregory J. Kaczorowski
      Molecular Pharmacology December 2011, 80 (6) 959-964; DOI: https://doi.org/10.1124/mol.111.074831

  6. Ko, Mei-Chuan

    1. Subunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence Time
      Diwahar Narasimhan, Gregory T. Collins, Mark R. Nance, Joseph Nichols, Elin Edwald, Jimmy Chan, Mei-Chuan Ko, James H. Woods, John J. G. Tesmer and Roger K. Sunahara
      Molecular Pharmacology December 2011, 80 (6) 1056-1065; DOI: https://doi.org/10.1124/mol.111.074997

  7. Kobayashi, Yoshiki

    1. p38 Mitogen-Activated Protein Kinase-γ Inhibition by Long-Acting β2 Adrenergic Agonists Reversed Steroid Insensitivity in Severe Asthma
      Nicholas Mercado, Yasuo To, Yoshiki Kobayashi, Ian M. Adcock, Peter J. Barnes and Kazuhiro Ito
      Molecular Pharmacology December 2011, 80 (6) 1128-1135; DOI: https://doi.org/10.1124/mol.111.071993

  8. Kots, Alexander Y.

    1. Restoring Soluble Guanylyl Cyclase Expression and Function Blocks the Aggressive Course of Glioma
      Haifeng Zhu, Jessica Tao Li, Fang Zheng, Emil Martin, Alexander Y. Kots, Joshua S. Krumenacker, Byung-Kwon Choi, Ian E. McCutcheon, Norman Weisbrodt, Oliver Bögler, Ferid Murad and Ka Bian
      Molecular Pharmacology December 2011, 80 (6) 1076-1084; DOI: https://doi.org/10.1124/mol.111.073585

  9. Krumenacker, Joshua S.

    1. Restoring Soluble Guanylyl Cyclase Expression and Function Blocks the Aggressive Course of Glioma
      Haifeng Zhu, Jessica Tao Li, Fang Zheng, Emil Martin, Alexander Y. Kots, Joshua S. Krumenacker, Byung-Kwon Choi, Ian E. McCutcheon, Norman Weisbrodt, Oliver Bögler, Ferid Murad and Ka Bian
      Molecular Pharmacology December 2011, 80 (6) 1076-1084; DOI: https://doi.org/10.1124/mol.111.073585

  10. Kugel Desmoulin, Sita

    1. Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Eric Hales, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology December 2011, 80 (6) 1096-1107; DOI: https://doi.org/10.1124/mol.111.073833

  11. Kushner, Juiwanna

    1. Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Eric Hales, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology December 2011, 80 (6) 1096-1107; DOI: https://doi.org/10.1124/mol.111.073833

L

  1. Langdon, Ronald B.

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

  2. Le Breton, Guy C.

    1. 2-Aminoethyl Methylphosphonate, a Potent and Rapidly Acting Antagonist of GABAA-ρ1 Receptors
      An Xie, Jun Yan, Lan Yue, Feng Feng, Fozia Mir, Heba Abdel-Halim, Mary Chebib, Guy C. Le Breton, Robert F. Standaert, Haohua Qian and David R. Pepperberg
      Molecular Pharmacology December 2011, 80 (6) 965-978; DOI: https://doi.org/10.1124/mol.111.071225

  3. Lee, Moo Yeol

    1. Nectandrin B Activates Endothelial Nitric-Oxide Synthase Phosphorylation in Endothelial Cells: Role of the AMP-Activated Protein Kinase/Estrogen Receptor α/Phosphatidylinositol 3-kinase/Akt Pathway
      Tran Thi Hien, Won Keun Oh, Phi Hung Nguyen, Seok Jeong Oh, Moo Yeol Lee and Keon Wook Kang
      Molecular Pharmacology December 2011, 80 (6) 1166-1178; DOI: https://doi.org/10.1124/mol.111.073502

  4. Lee, Yashang

    1. Reduced Level of Ribonucleotide Reductase R2 Subunits Increases Dependence on Homologous Recombination Repair of Cisplatin-Induced DNA Damage
      Z. Ping Lin, Yashang Lee, Fang Lin, Michael F. Belcourt, Peining Li, Joseph G. Cory, Peter M. Glazer and Alan C. Sartorelli
      Molecular Pharmacology December 2011, 80 (6) 1000-1012; DOI: https://doi.org/10.1124/mol.111.074708

  5. Leurs, Rob

    1. Identification of a Novel Allosteric Binding Site in the CXCR2 Chemokine Receptor
      Petra de Kruijf, Herman D. Lim, Luc Roumen, Véronique A. Renjaän, Jiuqiao Zhao, Maria L. Webb, Douglas S. Auld, Jac. C.H.M. Wijkmans, Guido J. R. Zaman, Martine J. Smit, Chris de Graaf and Rob Leurs
      Molecular Pharmacology December 2011, 80 (6) 1108-1118; DOI: https://doi.org/10.1124/mol.111.073825

  6. Li, Jessica Tao

    1. Restoring Soluble Guanylyl Cyclase Expression and Function Blocks the Aggressive Course of Glioma
      Haifeng Zhu, Jessica Tao Li, Fang Zheng, Emil Martin, Alexander Y. Kots, Joshua S. Krumenacker, Byung-Kwon Choi, Ian E. McCutcheon, Norman Weisbrodt, Oliver Bögler, Ferid Murad and Ka Bian
      Molecular Pharmacology December 2011, 80 (6) 1076-1084; DOI: https://doi.org/10.1124/mol.111.073585

  7. Li, Nina

    1. Identification of Novel and Selective KV2 Channel Inhibitors
      James Herrington, Kelli Solly, Kevin S. Ratliff, Nina Li, Yun-Ping Zhou, Andrew Howard, Laszlo Kiss, Maria L. Garcia, Owen B. McManus, Qiaolin Deng, Ranjit Desai, Yusheng Xiong and Gregory J. Kaczorowski
      Molecular Pharmacology December 2011, 80 (6) 959-964; DOI: https://doi.org/10.1124/mol.111.074831

  8. Li, Peining

    1. Reduced Level of Ribonucleotide Reductase R2 Subunits Increases Dependence on Homologous Recombination Repair of Cisplatin-Induced DNA Damage
      Z. Ping Lin, Yashang Lee, Fang Lin, Michael F. Belcourt, Peining Li, Joseph G. Cory, Peter M. Glazer and Alan C. Sartorelli
      Molecular Pharmacology December 2011, 80 (6) 1000-1012; DOI: https://doi.org/10.1124/mol.111.074708

  9. Lim, Herman D.

    1. Identification of a Novel Allosteric Binding Site in the CXCR2 Chemokine Receptor
      Petra de Kruijf, Herman D. Lim, Luc Roumen, Véronique A. Renjaän, Jiuqiao Zhao, Maria L. Webb, Douglas S. Auld, Jac. C.H.M. Wijkmans, Guido J. R. Zaman, Martine J. Smit, Chris de Graaf and Rob Leurs
      Molecular Pharmacology December 2011, 80 (6) 1108-1118; DOI: https://doi.org/10.1124/mol.111.073825

  10. Lin, Fang

    1. Reduced Level of Ribonucleotide Reductase R2 Subunits Increases Dependence on Homologous Recombination Repair of Cisplatin-Induced DNA Damage
      Z. Ping Lin, Yashang Lee, Fang Lin, Michael F. Belcourt, Peining Li, Joseph G. Cory, Peter M. Glazer and Alan C. Sartorelli
      Molecular Pharmacology December 2011, 80 (6) 1000-1012; DOI: https://doi.org/10.1124/mol.111.074708

  11. Lin, Songnian

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

  12. Lin, Z. Ping

    1. Reduced Level of Ribonucleotide Reductase R2 Subunits Increases Dependence on Homologous Recombination Repair of Cisplatin-Induced DNA Damage
      Z. Ping Lin, Yashang Lee, Fang Lin, Michael F. Belcourt, Peining Li, Joseph G. Cory, Peter M. Glazer and Alan C. Sartorelli
      Molecular Pharmacology December 2011, 80 (6) 1000-1012; DOI: https://doi.org/10.1124/mol.111.074708

  13. Lohse, Martin J.

    1. Developing Chemical Genetic Approaches to Explore G Protein-Coupled Receptor Function: Validation of the Use of a Receptor Activated Solely by Synthetic Ligand (RASSL)
      Elisa Alvarez-Curto, Rudi Prihandoko, Christofer S. Tautermann, Jurriaan M. Zwier, John D. Pediani, Martin J. Lohse, Carsten Hoffmann, Andrew B. Tobin and Graeme Milligan
      Molecular Pharmacology December 2011, 80 (6) 1033-1046; DOI: https://doi.org/10.1124/mol.111.074674

M

  1. Mahimainathan, Lenin

    1. Overexpression of Nrf2 Protects Cerebral Cortical Neurons from Ethanol-Induced Apoptotic Death
      Madhusudhanan Narasimhan, Lenin Mahimainathan, Mary Latha Rathinam, Amanjot Kaur Riar and George I. Henderson
      Molecular Pharmacology December 2011, 80 (6) 988-999; DOI: https://doi.org/10.1124/mol.111.073262

  2. Makishima, Makoto

    1. Dynamic and Ligand-Selective Interactions of Vitamin D Receptor with Retinoid X Receptor and Cofactors in Living Cells
      Mihwa Choi, Sachiko Yamada and Makoto Makishima
      Molecular Pharmacology December 2011, 80 (6) 1147-1155; DOI: https://doi.org/10.1124/mol.111.074138

  3. Martin, Emil

    1. Restoring Soluble Guanylyl Cyclase Expression and Function Blocks the Aggressive Course of Glioma
      Haifeng Zhu, Jessica Tao Li, Fang Zheng, Emil Martin, Alexander Y. Kots, Joshua S. Krumenacker, Byung-Kwon Choi, Ian E. McCutcheon, Norman Weisbrodt, Oliver Bögler, Ferid Murad and Ka Bian
      Molecular Pharmacology December 2011, 80 (6) 1076-1084; DOI: https://doi.org/10.1124/mol.111.073585

  4. Matherly, Larry H.

    1. Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Eric Hales, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology December 2011, 80 (6) 1096-1107; DOI: https://doi.org/10.1124/mol.111.073833

  5. Mauthe, Mario

    1. Ca2+/Calmodulin-Dependent Kinase (CaMK) Signaling via CaMKI and AMP-Activated Protein Kinase Contributes to the Regulation of WIPI-1 at the Onset of Autophagy
      Simon G. Pfisterer, Mario Mauthe, Patrice Codogno and Tassula Proikas-Cezanne
      Molecular Pharmacology December 2011, 80 (6) 1066-1075; DOI: https://doi.org/10.1124/mol.111.071761

  6. McCutcheon, Ian E.

    1. Restoring Soluble Guanylyl Cyclase Expression and Function Blocks the Aggressive Course of Glioma
      Haifeng Zhu, Jessica Tao Li, Fang Zheng, Emil Martin, Alexander Y. Kots, Joshua S. Krumenacker, Byung-Kwon Choi, Ian E. McCutcheon, Norman Weisbrodt, Oliver Bögler, Ferid Murad and Ka Bian
      Molecular Pharmacology December 2011, 80 (6) 1076-1084; DOI: https://doi.org/10.1124/mol.111.073585

  7. McManus, Owen B.

    1. Identification of Novel and Selective KV2 Channel Inhibitors
      James Herrington, Kelli Solly, Kevin S. Ratliff, Nina Li, Yun-Ping Zhou, Andrew Howard, Laszlo Kiss, Maria L. Garcia, Owen B. McManus, Qiaolin Deng, Ranjit Desai, Yusheng Xiong and Gregory J. Kaczorowski
      Molecular Pharmacology December 2011, 80 (6) 959-964; DOI: https://doi.org/10.1124/mol.111.074831

  8. Mercado, Nicholas

    1. p38 Mitogen-Activated Protein Kinase-γ Inhibition by Long-Acting β2 Adrenergic Agonists Reversed Steroid Insensitivity in Severe Asthma
      Nicholas Mercado, Yasuo To, Yoshiki Kobayashi, Ian M. Adcock, Peter J. Barnes and Kazuhiro Ito
      Molecular Pharmacology December 2011, 80 (6) 1128-1135; DOI: https://doi.org/10.1124/mol.111.071993

  9. Michel, Martin C.

    1. How Can 1 + 1 = 3? β2-Adrenergic and Glucocorticoid Receptor Agonist Synergism in Obstructive Airway Diseases
      Martina Schmidt and Martin C. Michel
      Molecular Pharmacology December 2011, 80 (6) 955-958; DOI: https://doi.org/10.1124/mol.111.075481

  10. Milligan, Graeme

    1. Developing Chemical Genetic Approaches to Explore G Protein-Coupled Receptor Function: Validation of the Use of a Receptor Activated Solely by Synthetic Ligand (RASSL)
      Elisa Alvarez-Curto, Rudi Prihandoko, Christofer S. Tautermann, Jurriaan M. Zwier, John D. Pediani, Martin J. Lohse, Carsten Hoffmann, Andrew B. Tobin and Graeme Milligan
      Molecular Pharmacology December 2011, 80 (6) 1033-1046; DOI: https://doi.org/10.1124/mol.111.074674

  11. Mir, Fozia

    1. 2-Aminoethyl Methylphosphonate, a Potent and Rapidly Acting Antagonist of GABAA-ρ1 Receptors
      An Xie, Jun Yan, Lan Yue, Feng Feng, Fozia Mir, Heba Abdel-Halim, Mary Chebib, Guy C. Le Breton, Robert F. Standaert, Haohua Qian and David R. Pepperberg
      Molecular Pharmacology December 2011, 80 (6) 965-978; DOI: https://doi.org/10.1124/mol.111.071225

  12. Moroni, Flavio

    1. Pharmacological Effects of Exogenous NAD on Mitochondrial Bioenergetics, DNA Repair, and Apoptosis
      Maria Pittelli, Roberta Felici, Vanessa Pitozzi, Lisa Giovannelli, Elisabetta Bigagli, Francesca Cialdai, Giovanni Romano, Flavio Moroni and Alberto Chiarugi
      Molecular Pharmacology December 2011, 80 (6) 1136-1146; DOI: https://doi.org/10.1124/mol.111.073916

  13. Müller, Isabelle

    1. Pregnenolone Sulfate Activates Basic Region Leucine Zipper Transcription Factors in Insulinoma Cells: Role of Voltage-Gated Ca2+ Channels and Transient Receptor Potential Melastatin 3 Channels
      Isabelle Müller, Oliver G. Rössler and Gerald Thiel
      Molecular Pharmacology December 2011, 80 (6) 1179-1189; DOI: https://doi.org/10.1124/mol.111.074781

  14. Murad, Ferid

    1. Restoring Soluble Guanylyl Cyclase Expression and Function Blocks the Aggressive Course of Glioma
      Haifeng Zhu, Jessica Tao Li, Fang Zheng, Emil Martin, Alexander Y. Kots, Joshua S. Krumenacker, Byung-Kwon Choi, Ian E. McCutcheon, Norman Weisbrodt, Oliver Bögler, Ferid Murad and Ka Bian
      Molecular Pharmacology December 2011, 80 (6) 1076-1084; DOI: https://doi.org/10.1124/mol.111.073585

N

  1. Nagata, Yasufumi

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

  2. Nance, Mark R.

    1. Subunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence Time
      Diwahar Narasimhan, Gregory T. Collins, Mark R. Nance, Joseph Nichols, Elin Edwald, Jimmy Chan, Mei-Chuan Ko, James H. Woods, John J. G. Tesmer and Roger K. Sunahara
      Molecular Pharmacology December 2011, 80 (6) 1056-1065; DOI: https://doi.org/10.1124/mol.111.074997

  3. Narasimhan, Diwahar

    1. The Ability of Bacterial Cocaine Esterase to Hydrolyze Cocaine Metabolites and Their Simultaneous Quantification Using High-Performance Liquid Chromatography-Tandem Mass Spectrometry
      Remy L. Brim, Kathleen R. Noon, Gregory T. Collins, Joseph Nichols, Diwahar Narasimhan, Roger K. Sunahara and James H. Woods
      Molecular Pharmacology December 2011, 80 (6) 1119-1127; DOI: https://doi.org/10.1124/mol.111.074534
    2. Subunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence Time
      Diwahar Narasimhan, Gregory T. Collins, Mark R. Nance, Joseph Nichols, Elin Edwald, Jimmy Chan, Mei-Chuan Ko, James H. Woods, John J. G. Tesmer and Roger K. Sunahara
      Molecular Pharmacology December 2011, 80 (6) 1056-1065; DOI: https://doi.org/10.1124/mol.111.074997

  4. Narasimhan, Madhusudhanan

    1. Overexpression of Nrf2 Protects Cerebral Cortical Neurons from Ethanol-Induced Apoptotic Death
      Madhusudhanan Narasimhan, Lenin Mahimainathan, Mary Latha Rathinam, Amanjot Kaur Riar and George I. Henderson
      Molecular Pharmacology December 2011, 80 (6) 988-999; DOI: https://doi.org/10.1124/mol.111.073262

  5. Nguyen, Phi Hung

    1. Nectandrin B Activates Endothelial Nitric-Oxide Synthase Phosphorylation in Endothelial Cells: Role of the AMP-Activated Protein Kinase/Estrogen Receptor α/Phosphatidylinositol 3-kinase/Akt Pathway
      Tran Thi Hien, Won Keun Oh, Phi Hung Nguyen, Seok Jeong Oh, Moo Yeol Lee and Keon Wook Kang
      Molecular Pharmacology December 2011, 80 (6) 1166-1178; DOI: https://doi.org/10.1124/mol.111.073502

  6. Nichols, Joseph

    1. The Ability of Bacterial Cocaine Esterase to Hydrolyze Cocaine Metabolites and Their Simultaneous Quantification Using High-Performance Liquid Chromatography-Tandem Mass Spectrometry
      Remy L. Brim, Kathleen R. Noon, Gregory T. Collins, Joseph Nichols, Diwahar Narasimhan, Roger K. Sunahara and James H. Woods
      Molecular Pharmacology December 2011, 80 (6) 1119-1127; DOI: https://doi.org/10.1124/mol.111.074534
    2. Subunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence Time
      Diwahar Narasimhan, Gregory T. Collins, Mark R. Nance, Joseph Nichols, Elin Edwald, Jimmy Chan, Mei-Chuan Ko, James H. Woods, John J. G. Tesmer and Roger K. Sunahara
      Molecular Pharmacology December 2011, 80 (6) 1056-1065; DOI: https://doi.org/10.1124/mol.111.074997

  7. Nishimura, Teruyuki

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

  8. Noon, Kathleen R.

    1. The Ability of Bacterial Cocaine Esterase to Hydrolyze Cocaine Metabolites and Their Simultaneous Quantification Using High-Performance Liquid Chromatography-Tandem Mass Spectrometry
      Remy L. Brim, Kathleen R. Noon, Gregory T. Collins, Joseph Nichols, Diwahar Narasimhan, Roger K. Sunahara and James H. Woods
      Molecular Pharmacology December 2011, 80 (6) 1119-1127; DOI: https://doi.org/10.1124/mol.111.074534

O

  1. Oh, Seok Jeong

    1. Nectandrin B Activates Endothelial Nitric-Oxide Synthase Phosphorylation in Endothelial Cells: Role of the AMP-Activated Protein Kinase/Estrogen Receptor α/Phosphatidylinositol 3-kinase/Akt Pathway
      Tran Thi Hien, Won Keun Oh, Phi Hung Nguyen, Seok Jeong Oh, Moo Yeol Lee and Keon Wook Kang
      Molecular Pharmacology December 2011, 80 (6) 1166-1178; DOI: https://doi.org/10.1124/mol.111.073502

  2. Oh, Won Keun

    1. Nectandrin B Activates Endothelial Nitric-Oxide Synthase Phosphorylation in Endothelial Cells: Role of the AMP-Activated Protein Kinase/Estrogen Receptor α/Phosphatidylinositol 3-kinase/Akt Pathway
      Tran Thi Hien, Won Keun Oh, Phi Hung Nguyen, Seok Jeong Oh, Moo Yeol Lee and Keon Wook Kang
      Molecular Pharmacology December 2011, 80 (6) 1166-1178; DOI: https://doi.org/10.1124/mol.111.073502

  3. Ohe, Tomoyuki

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

  4. Ohyama, Sumika

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

P

  1. Papke, Roger L.

    1. Investigation of the Molecular Mechanism of the α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator PNU-120596 Provides Evidence for Two Distinct Desensitized States
      Dustin K. Williams, Jingyi Wang and Roger L. Papke
      Molecular Pharmacology December 2011, 80 (6) 1013-1032; DOI: https://doi.org/10.1124/mol.111.074302

  2. Pascual, Jaime

    1. Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains
      Manish B. Shah, Jaime Pascual, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology December 2011, 80 (6) 1047-1055; DOI: https://doi.org/10.1124/mol.111.074427

  3. Pediani, John D.

    1. Developing Chemical Genetic Approaches to Explore G Protein-Coupled Receptor Function: Validation of the Use of a Receptor Activated Solely by Synthetic Ligand (RASSL)
      Elisa Alvarez-Curto, Rudi Prihandoko, Christofer S. Tautermann, Jurriaan M. Zwier, John D. Pediani, Martin J. Lohse, Carsten Hoffmann, Andrew B. Tobin and Graeme Milligan
      Molecular Pharmacology December 2011, 80 (6) 1033-1046; DOI: https://doi.org/10.1124/mol.111.074674

  4. Pepperberg, David R.

    1. 2-Aminoethyl Methylphosphonate, a Potent and Rapidly Acting Antagonist of GABAA-ρ1 Receptors
      An Xie, Jun Yan, Lan Yue, Feng Feng, Fozia Mir, Heba Abdel-Halim, Mary Chebib, Guy C. Le Breton, Robert F. Standaert, Haohua Qian and David R. Pepperberg
      Molecular Pharmacology December 2011, 80 (6) 965-978; DOI: https://doi.org/10.1124/mol.111.071225

  5. Pfisterer, Simon G.

    1. Ca2+/Calmodulin-Dependent Kinase (CaMK) Signaling via CaMKI and AMP-Activated Protein Kinase Contributes to the Regulation of WIPI-1 at the Onset of Autophagy
      Simon G. Pfisterer, Mario Mauthe, Patrice Codogno and Tassula Proikas-Cezanne
      Molecular Pharmacology December 2011, 80 (6) 1066-1075; DOI: https://doi.org/10.1124/mol.111.071761

  6. Pitozzi, Vanessa

    1. Pharmacological Effects of Exogenous NAD on Mitochondrial Bioenergetics, DNA Repair, and Apoptosis
      Maria Pittelli, Roberta Felici, Vanessa Pitozzi, Lisa Giovannelli, Elisabetta Bigagli, Francesca Cialdai, Giovanni Romano, Flavio Moroni and Alberto Chiarugi
      Molecular Pharmacology December 2011, 80 (6) 1136-1146; DOI: https://doi.org/10.1124/mol.111.073916

  7. Pittelli, Maria

    1. Pharmacological Effects of Exogenous NAD on Mitochondrial Bioenergetics, DNA Repair, and Apoptosis
      Maria Pittelli, Roberta Felici, Vanessa Pitozzi, Lisa Giovannelli, Elisabetta Bigagli, Francesca Cialdai, Giovanni Romano, Flavio Moroni and Alberto Chiarugi
      Molecular Pharmacology December 2011, 80 (6) 1136-1146; DOI: https://doi.org/10.1124/mol.111.073916

  8. Polin, Lisa

    1. Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Eric Hales, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology December 2011, 80 (6) 1096-1107; DOI: https://doi.org/10.1124/mol.111.073833

  9. Prihandoko, Rudi

    1. Developing Chemical Genetic Approaches to Explore G Protein-Coupled Receptor Function: Validation of the Use of a Receptor Activated Solely by Synthetic Ligand (RASSL)
      Elisa Alvarez-Curto, Rudi Prihandoko, Christofer S. Tautermann, Jurriaan M. Zwier, John D. Pediani, Martin J. Lohse, Carsten Hoffmann, Andrew B. Tobin and Graeme Milligan
      Molecular Pharmacology December 2011, 80 (6) 1033-1046; DOI: https://doi.org/10.1124/mol.111.074674

  10. Proikas-Cezanne, Tassula

    1. Ca2+/Calmodulin-Dependent Kinase (CaMK) Signaling via CaMKI and AMP-Activated Protein Kinase Contributes to the Regulation of WIPI-1 at the Onset of Autophagy
      Simon G. Pfisterer, Mario Mauthe, Patrice Codogno and Tassula Proikas-Cezanne
      Molecular Pharmacology December 2011, 80 (6) 1066-1075; DOI: https://doi.org/10.1124/mol.111.071761

Q

  1. Qian, Haohua

    1. 2-Aminoethyl Methylphosphonate, a Potent and Rapidly Acting Antagonist of GABAA-ρ1 Receptors
      An Xie, Jun Yan, Lan Yue, Feng Feng, Fozia Mir, Heba Abdel-Halim, Mary Chebib, Guy C. Le Breton, Robert F. Standaert, Haohua Qian and David R. Pepperberg
      Molecular Pharmacology December 2011, 80 (6) 965-978; DOI: https://doi.org/10.1124/mol.111.071225

R

  1. Rathinam, Mary Latha

    1. Overexpression of Nrf2 Protects Cerebral Cortical Neurons from Ethanol-Induced Apoptotic Death
      Madhusudhanan Narasimhan, Lenin Mahimainathan, Mary Latha Rathinam, Amanjot Kaur Riar and George I. Henderson
      Molecular Pharmacology December 2011, 80 (6) 988-999; DOI: https://doi.org/10.1124/mol.111.073262

  2. Ratliff, Kevin S.

    1. Identification of Novel and Selective KV2 Channel Inhibitors
      James Herrington, Kelli Solly, Kevin S. Ratliff, Nina Li, Yun-Ping Zhou, Andrew Howard, Laszlo Kiss, Maria L. Garcia, Owen B. McManus, Qiaolin Deng, Ranjit Desai, Yusheng Xiong and Gregory J. Kaczorowski
      Molecular Pharmacology December 2011, 80 (6) 959-964; DOI: https://doi.org/10.1124/mol.111.074831

  3. Renjaän, Véronique A.

    1. Identification of a Novel Allosteric Binding Site in the CXCR2 Chemokine Receptor
      Petra de Kruijf, Herman D. Lim, Luc Roumen, Véronique A. Renjaän, Jiuqiao Zhao, Maria L. Webb, Douglas S. Auld, Jac. C.H.M. Wijkmans, Guido J. R. Zaman, Martine J. Smit, Chris de Graaf and Rob Leurs
      Molecular Pharmacology December 2011, 80 (6) 1108-1118; DOI: https://doi.org/10.1124/mol.111.073825

  4. Riar, Amanjot Kaur

    1. Overexpression of Nrf2 Protects Cerebral Cortical Neurons from Ethanol-Induced Apoptotic Death
      Madhusudhanan Narasimhan, Lenin Mahimainathan, Mary Latha Rathinam, Amanjot Kaur Riar and George I. Henderson
      Molecular Pharmacology December 2011, 80 (6) 988-999; DOI: https://doi.org/10.1124/mol.111.073262

  5. Romano, Giovanni

    1. Pharmacological Effects of Exogenous NAD on Mitochondrial Bioenergetics, DNA Repair, and Apoptosis
      Maria Pittelli, Roberta Felici, Vanessa Pitozzi, Lisa Giovannelli, Elisabetta Bigagli, Francesca Cialdai, Giovanni Romano, Flavio Moroni and Alberto Chiarugi
      Molecular Pharmacology December 2011, 80 (6) 1136-1146; DOI: https://doi.org/10.1124/mol.111.073916

  6. Rössler, Oliver G.

    1. Pregnenolone Sulfate Activates Basic Region Leucine Zipper Transcription Factors in Insulinoma Cells: Role of Voltage-Gated Ca2+ Channels and Transient Receptor Potential Melastatin 3 Channels
      Isabelle Müller, Oliver G. Rössler and Gerald Thiel
      Molecular Pharmacology December 2011, 80 (6) 1179-1189; DOI: https://doi.org/10.1124/mol.111.074781

  7. Roumen, Luc

    1. Identification of a Novel Allosteric Binding Site in the CXCR2 Chemokine Receptor
      Petra de Kruijf, Herman D. Lim, Luc Roumen, Véronique A. Renjaän, Jiuqiao Zhao, Maria L. Webb, Douglas S. Auld, Jac. C.H.M. Wijkmans, Guido J. R. Zaman, Martine J. Smit, Chris de Graaf and Rob Leurs
      Molecular Pharmacology December 2011, 80 (6) 1108-1118; DOI: https://doi.org/10.1124/mol.111.073825

S

  1. Sartorelli, Alan C.

    1. Reduced Level of Ribonucleotide Reductase R2 Subunits Increases Dependence on Homologous Recombination Repair of Cisplatin-Induced DNA Damage
      Z. Ping Lin, Yashang Lee, Fang Lin, Michael F. Belcourt, Peining Li, Joseph G. Cory, Peter M. Glazer and Alan C. Sartorelli
      Molecular Pharmacology December 2011, 80 (6) 1000-1012; DOI: https://doi.org/10.1124/mol.111.074708

  2. Sasaki-Yamamoto, Kaori

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

  3. Schmidt, Martina

    1. How Can 1 + 1 = 3? β2-Adrenergic and Glucocorticoid Receptor Agonist Synergism in Obstructive Airway Diseases
      Martina Schmidt and Martin C. Michel
      Molecular Pharmacology December 2011, 80 (6) 955-958; DOI: https://doi.org/10.1124/mol.111.075481

  4. Shah, Manish B.

    1. Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains
      Manish B. Shah, Jaime Pascual, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology December 2011, 80 (6) 1047-1055; DOI: https://doi.org/10.1124/mol.111.074427

  5. Smit, Martine J.

    1. Identification of a Novel Allosteric Binding Site in the CXCR2 Chemokine Receptor
      Petra de Kruijf, Herman D. Lim, Luc Roumen, Véronique A. Renjaän, Jiuqiao Zhao, Maria L. Webb, Douglas S. Auld, Jac. C.H.M. Wijkmans, Guido J. R. Zaman, Martine J. Smit, Chris de Graaf and Rob Leurs
      Molecular Pharmacology December 2011, 80 (6) 1108-1118; DOI: https://doi.org/10.1124/mol.111.073825

  6. Solly, Kelli

    1. Identification of Novel and Selective KV2 Channel Inhibitors
      James Herrington, Kelli Solly, Kevin S. Ratliff, Nina Li, Yun-Ping Zhou, Andrew Howard, Laszlo Kiss, Maria L. Garcia, Owen B. McManus, Qiaolin Deng, Ranjit Desai, Yusheng Xiong and Gregory J. Kaczorowski
      Molecular Pharmacology December 2011, 80 (6) 959-964; DOI: https://doi.org/10.1124/mol.111.074831

  7. Standaert, Robert F.

    1. 2-Aminoethyl Methylphosphonate, a Potent and Rapidly Acting Antagonist of GABAA-ρ1 Receptors
      An Xie, Jun Yan, Lan Yue, Feng Feng, Fozia Mir, Heba Abdel-Halim, Mary Chebib, Guy C. Le Breton, Robert F. Standaert, Haohua Qian and David R. Pepperberg
      Molecular Pharmacology December 2011, 80 (6) 965-978; DOI: https://doi.org/10.1124/mol.111.071225

  8. Stout, C. David

    1. Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains
      Manish B. Shah, Jaime Pascual, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology December 2011, 80 (6) 1047-1055; DOI: https://doi.org/10.1124/mol.111.074427

  9. Stout, Mark

    1. Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Eric Hales, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology December 2011, 80 (6) 1096-1107; DOI: https://doi.org/10.1124/mol.111.073833

  10. Sunahara, Roger K.

    1. The Ability of Bacterial Cocaine Esterase to Hydrolyze Cocaine Metabolites and Their Simultaneous Quantification Using High-Performance Liquid Chromatography-Tandem Mass Spectrometry
      Remy L. Brim, Kathleen R. Noon, Gregory T. Collins, Joseph Nichols, Diwahar Narasimhan, Roger K. Sunahara and James H. Woods
      Molecular Pharmacology December 2011, 80 (6) 1119-1127; DOI: https://doi.org/10.1124/mol.111.074534
    2. Subunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence Time
      Diwahar Narasimhan, Gregory T. Collins, Mark R. Nance, Joseph Nichols, Elin Edwald, Jimmy Chan, Mei-Chuan Ko, James H. Woods, John J. G. Tesmer and Roger K. Sunahara
      Molecular Pharmacology December 2011, 80 (6) 1056-1065; DOI: https://doi.org/10.1124/mol.111.074997

  11. Swartz, Kenton J.

    1. Elucidating the Molecular Basis of Action of a Classic Drug: Guanidine Compounds As Inhibitors of Voltage-Gated Potassium Channels
      Jeet Kalia and Kenton J. Swartz
      Molecular Pharmacology December 2011, 80 (6) 1085-1095; DOI: https://doi.org/10.1124/mol.111.074989

T

  1. Tautermann, Christofer S.

    1. Developing Chemical Genetic Approaches to Explore G Protein-Coupled Receptor Function: Validation of the Use of a Receptor Activated Solely by Synthetic Ligand (RASSL)
      Elisa Alvarez-Curto, Rudi Prihandoko, Christofer S. Tautermann, Jurriaan M. Zwier, John D. Pediani, Martin J. Lohse, Carsten Hoffmann, Andrew B. Tobin and Graeme Milligan
      Molecular Pharmacology December 2011, 80 (6) 1033-1046; DOI: https://doi.org/10.1124/mol.111.074674

  2. Tesmer, John J. G.

    1. Subunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence Time
      Diwahar Narasimhan, Gregory T. Collins, Mark R. Nance, Joseph Nichols, Elin Edwald, Jimmy Chan, Mei-Chuan Ko, James H. Woods, John J. G. Tesmer and Roger K. Sunahara
      Molecular Pharmacology December 2011, 80 (6) 1056-1065; DOI: https://doi.org/10.1124/mol.111.074997

  3. Thiel, Gerald

    1. Pregnenolone Sulfate Activates Basic Region Leucine Zipper Transcription Factors in Insulinoma Cells: Role of Voltage-Gated Ca2+ Channels and Transient Receptor Potential Melastatin 3 Channels
      Isabelle Müller, Oliver G. Rössler and Gerald Thiel
      Molecular Pharmacology December 2011, 80 (6) 1179-1189; DOI: https://doi.org/10.1124/mol.111.074781

  4. To, Yasuo

    1. p38 Mitogen-Activated Protein Kinase-γ Inhibition by Long-Acting β2 Adrenergic Agonists Reversed Steroid Insensitivity in Severe Asthma
      Nicholas Mercado, Yasuo To, Yoshiki Kobayashi, Ian M. Adcock, Peter J. Barnes and Kazuhiro Ito
      Molecular Pharmacology December 2011, 80 (6) 1128-1135; DOI: https://doi.org/10.1124/mol.111.071993

  5. Tobin, Andrew B.

    1. Developing Chemical Genetic Approaches to Explore G Protein-Coupled Receptor Function: Validation of the Use of a Receptor Activated Solely by Synthetic Ligand (RASSL)
      Elisa Alvarez-Curto, Rudi Prihandoko, Christofer S. Tautermann, Jurriaan M. Zwier, John D. Pediani, Martin J. Lohse, Carsten Hoffmann, Andrew B. Tobin and Graeme Milligan
      Molecular Pharmacology December 2011, 80 (6) 1033-1046; DOI: https://doi.org/10.1124/mol.111.074674

  6. Tung, Emily W. Y.

    1. Valproic Acid Increases Formation of Reactive Oxygen Species and Induces Apoptosis in Postimplantation Embryos: A Role for Oxidative Stress in Valproic Acid-Induced Neural Tube Defects
      Emily W. Y. Tung and Louise M. Winn
      Molecular Pharmacology December 2011, 80 (6) 979-987; DOI: https://doi.org/10.1124/mol.111.072314

W

  1. Wang, Jingyi

    1. Investigation of the Molecular Mechanism of the α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator PNU-120596 Provides Evidence for Two Distinct Desensitized States
      Dustin K. Williams, Jingyi Wang and Roger L. Papke
      Molecular Pharmacology December 2011, 80 (6) 1013-1032; DOI: https://doi.org/10.1124/mol.111.074302

  2. Wang, Lei

    1. Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Eric Hales, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology December 2011, 80 (6) 1096-1107; DOI: https://doi.org/10.1124/mol.111.073833

  3. Webb, Maria L.

    1. Identification of a Novel Allosteric Binding Site in the CXCR2 Chemokine Receptor
      Petra de Kruijf, Herman D. Lim, Luc Roumen, Véronique A. Renjaän, Jiuqiao Zhao, Maria L. Webb, Douglas S. Auld, Jac. C.H.M. Wijkmans, Guido J. R. Zaman, Martine J. Smit, Chris de Graaf and Rob Leurs
      Molecular Pharmacology December 2011, 80 (6) 1108-1118; DOI: https://doi.org/10.1124/mol.111.073825

  4. Weisbrodt, Norman

    1. Restoring Soluble Guanylyl Cyclase Expression and Function Blocks the Aggressive Course of Glioma
      Haifeng Zhu, Jessica Tao Li, Fang Zheng, Emil Martin, Alexander Y. Kots, Joshua S. Krumenacker, Byung-Kwon Choi, Ian E. McCutcheon, Norman Weisbrodt, Oliver Bögler, Ferid Murad and Ka Bian
      Molecular Pharmacology December 2011, 80 (6) 1076-1084; DOI: https://doi.org/10.1124/mol.111.073585

  5. White, Kathryn

    1. Therapeutic Targeting of a Novel 6-Substituted Pyrrolo [2,3-d]pyrimidine Thienoyl Antifolate to Human Solid Tumors Based on Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Eric Hales, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology December 2011, 80 (6) 1096-1107; DOI: https://doi.org/10.1124/mol.111.073833

  6. Wijkmans, Jac. C.H.M.

    1. Identification of a Novel Allosteric Binding Site in the CXCR2 Chemokine Receptor
      Petra de Kruijf, Herman D. Lim, Luc Roumen, Véronique A. Renjaän, Jiuqiao Zhao, Maria L. Webb, Douglas S. Auld, Jac. C.H.M. Wijkmans, Guido J. R. Zaman, Martine J. Smit, Chris de Graaf and Rob Leurs
      Molecular Pharmacology December 2011, 80 (6) 1108-1118; DOI: https://doi.org/10.1124/mol.111.073825

  7. Williams, Dustin K.

    1. Investigation of the Molecular Mechanism of the α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator PNU-120596 Provides Evidence for Two Distinct Desensitized States
      Dustin K. Williams, Jingyi Wang and Roger L. Papke
      Molecular Pharmacology December 2011, 80 (6) 1013-1032; DOI: https://doi.org/10.1124/mol.111.074302

  8. Winn, Louise M.

    1. Valproic Acid Increases Formation of Reactive Oxygen Species and Induces Apoptosis in Postimplantation Embryos: A Role for Oxidative Stress in Valproic Acid-Induced Neural Tube Defects
      Emily W. Y. Tung and Louise M. Winn
      Molecular Pharmacology December 2011, 80 (6) 979-987; DOI: https://doi.org/10.1124/mol.111.072314

  9. Woods, James H.

    1. The Ability of Bacterial Cocaine Esterase to Hydrolyze Cocaine Metabolites and Their Simultaneous Quantification Using High-Performance Liquid Chromatography-Tandem Mass Spectrometry
      Remy L. Brim, Kathleen R. Noon, Gregory T. Collins, Joseph Nichols, Diwahar Narasimhan, Roger K. Sunahara and James H. Woods
      Molecular Pharmacology December 2011, 80 (6) 1119-1127; DOI: https://doi.org/10.1124/mol.111.074534
    2. Subunit Stabilization and Polyethylene Glycolation of Cocaine Esterase Improves In Vivo Residence Time
      Diwahar Narasimhan, Gregory T. Collins, Mark R. Nance, Joseph Nichols, Elin Edwald, Jimmy Chan, Mei-Chuan Ko, James H. Woods, John J. G. Tesmer and Roger K. Sunahara
      Molecular Pharmacology December 2011, 80 (6) 1056-1065; DOI: https://doi.org/10.1124/mol.111.074997

X

  1. Xie, An

    1. 2-Aminoethyl Methylphosphonate, a Potent and Rapidly Acting Antagonist of GABAA-ρ1 Receptors
      An Xie, Jun Yan, Lan Yue, Feng Feng, Fozia Mir, Heba Abdel-Halim, Mary Chebib, Guy C. Le Breton, Robert F. Standaert, Haohua Qian and David R. Pepperberg
      Molecular Pharmacology December 2011, 80 (6) 965-978; DOI: https://doi.org/10.1124/mol.111.071225

  2. Xiong, Yusheng

    1. Identification of Novel and Selective KV2 Channel Inhibitors
      James Herrington, Kelli Solly, Kevin S. Ratliff, Nina Li, Yun-Ping Zhou, Andrew Howard, Laszlo Kiss, Maria L. Garcia, Owen B. McManus, Qiaolin Deng, Ranjit Desai, Yusheng Xiong and Gregory J. Kaczorowski
      Molecular Pharmacology December 2011, 80 (6) 959-964; DOI: https://doi.org/10.1124/mol.111.074831

Y

  1. Yamada, Sachiko

    1. Dynamic and Ligand-Selective Interactions of Vitamin D Receptor with Retinoid X Receptor and Cofactors in Living Cells
      Mihwa Choi, Sachiko Yamada and Makoto Makishima
      Molecular Pharmacology December 2011, 80 (6) 1147-1155; DOI: https://doi.org/10.1124/mol.111.074138

  2. Yan, Jun

    1. 2-Aminoethyl Methylphosphonate, a Potent and Rapidly Acting Antagonist of GABAA-ρ1 Receptors
      An Xie, Jun Yan, Lan Yue, Feng Feng, Fozia Mir, Heba Abdel-Halim, Mary Chebib, Guy C. Le Breton, Robert F. Standaert, Haohua Qian and David R. Pepperberg
      Molecular Pharmacology December 2011, 80 (6) 965-978; DOI: https://doi.org/10.1124/mol.111.071225

  3. Yoshida-Yoshimioto, Riki

    1. Pharmacokinetic and Pharmacodynamic Properties of the Glucokinase Activator MK-0941 in Rodent Models of Type 2 Diabetes and Healthy Dogs
      Jun-ichi Eiki, Yasufumi Nagata, Mayumi Futamura, Kaori Sasaki-Yamamoto, Tomoharu Iino, Teruyuki Nishimura, Masato Chiba, Sumika Ohyama, Riki Yoshida-Yoshimioto, Kenji Fujii, Hideka Hosaka, Hiroko Goto-Shimazaki, Akito Kadotani, Tomoyuki Ohe, Songnian Lin, Ronald B. Langdon and Joel P. Berger
      Molecular Pharmacology December 2011, 80 (6) 1156-1165; DOI: https://doi.org/10.1124/mol.111.074401

  4. Yue, Lan

    1. 2-Aminoethyl Methylphosphonate, a Potent and Rapidly Acting Antagonist of GABAA-ρ1 Receptors
      An Xie, Jun Yan, Lan Yue, Feng Feng, Fozia Mir, Heba Abdel-Halim, Mary Chebib, Guy C. Le Breton, Robert F. Standaert, Haohua Qian and David R. Pepperberg
      Molecular Pharmacology December 2011, 80 (6) 965-978; DOI: https://doi.org/10.1124/mol.111.071225

Z

  1. Zaman, Guido J. R.

    1. Identification of a Novel Allosteric Binding Site in the CXCR2 Chemokine Receptor
      Petra de Kruijf, Herman D. Lim, Luc Roumen, Véronique A. Renjaän, Jiuqiao Zhao, Maria L. Webb, Douglas S. Auld, Jac. C.H.M. Wijkmans, Guido J. R. Zaman, Martine J. Smit, Chris de Graaf and Rob Leurs
      Molecular Pharmacology December 2011, 80 (6) 1108-1118; DOI: https://doi.org/10.1124/mol.111.073825

  2. Zhang, Qinghai

    1. Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains
      Manish B. Shah, Jaime Pascual, Qinghai Zhang, C. David Stout and James R. Halpert
      Molecular Pharmacology December 2011, 80 (6) 1047-1055; DOI: https://doi.org/10.1124/mol.111.074427

  3. Zhao, Jiuqiao

    1. Identification of a Novel Allosteric Binding Site in the CXCR2 Chemokine Receptor
      Petra de Kruijf, Herman D. Lim, Luc Roumen, Véronique A. Renjaän, Jiuqiao Zhao, Maria L. Webb, Douglas S. Auld, Jac. C.H.M. Wijkmans, Guido J. R. Zaman, Martine J. Smit, Chris de Graaf and Rob Leurs
      Molecular Pharmacology December 2011, 80 (6) 1108-1118; DOI: https://doi.org/10.1124/mol.111.073825

  4. Zheng, Fang

    1. Restoring Soluble Guanylyl Cyclase Expression and Function Blocks the Aggressive Course of Glioma
      Haifeng Zhu, Jessica Tao Li, Fang Zheng, Emil Martin, Alexander Y. Kots, Joshua S. Krumenacker, Byung-Kwon Choi, Ian E. McCutcheon, Norman Weisbrodt, Oliver Bögler, Ferid Murad and Ka Bian
      Molecular Pharmacology December 2011, 80 (6) 1076-1084; DOI: https://doi.org/10.1124/mol.111.073585

  5. Zhou, Yun-Ping

    1. Identification of Novel and Selective KV2 Channel Inhibitors
      James Herrington, Kelli Solly, Kevin S. Ratliff, Nina Li, Yun-Ping Zhou, Andrew Howard, Laszlo Kiss, Maria L. Garcia, Owen B. McManus, Qiaolin Deng, Ranjit Desai, Yusheng Xiong and Gregory J. Kaczorowski
      Molecular Pharmacology December 2011, 80 (6) 959-964; DOI: https://doi.org/10.1124/mol.111.074831

  6. Zhu, Haifeng

    1. Restoring Soluble Guanylyl Cyclase Expression and Function Blocks the Aggressive Course of Glioma
      Haifeng Zhu, Jessica Tao Li, Fang Zheng, Emil Martin, Alexander Y. Kots, Joshua S. Krumenacker, Byung-Kwon Choi, Ian E. McCutcheon, Norman Weisbrodt, Oliver Bögler, Ferid Murad and Ka Bian
      Molecular Pharmacology December 2011, 80 (6) 1076-1084; DOI: https://doi.org/10.1124/mol.111.073585

  7. Zwier, Jurriaan M.

    1. Developing Chemical Genetic Approaches to Explore G Protein-Coupled Receptor Function: Validation of the Use of a Receptor Activated Solely by Synthetic Ligand (RASSL)
      Elisa Alvarez-Curto, Rudi Prihandoko, Christofer S. Tautermann, Jurriaan M. Zwier, John D. Pediani, Martin J. Lohse, Carsten Hoffmann, Andrew B. Tobin and Graeme Milligan
      Molecular Pharmacology December 2011, 80 (6) 1033-1046; DOI: https://doi.org/10.1124/mol.111.074674
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