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Molecular Pharmacology

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Table of Contents

January 01, 2012; Volume 81,Issue 1

Editor's Note

  • You have access
    Editor's Note: Technological Advances and a Molecular Understanding of Pharmacology
    Stephen F. Traynelis,
    Molecular Pharmacology January 2012, 81 (1) 1-2; DOI: https://doi.org/10.1124/mol.81.1.1

Articles

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    Development of Novel CH223191-Based Antagonists of the Aryl Hydrocarbon Receptor
    Eun-Young Choi, Hyosung Lee, R. W. Cameron Dingle, Kyung Bo Kim and Hollie I. Swanson
    Molecular Pharmacology January 2012, 81 (1) 3-11; DOI: https://doi.org/10.1124/mol.111.073643
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    Estrogen Receptors and Type 1 Metabotropic Glutamate Receptors Are Interdependent in Protecting Cortical Neurons against β-Amyloid Toxicity
    Simona Federica Spampinato, Gemma Molinaro, Sara Merlo, Luisa Iacovelli, Filippo Caraci, Giuseppe Battaglia, Ferdinando Nicoletti, Valeria Bruno and Maria Angela Sortino
    Molecular Pharmacology January 2012, 81 (1) 12-20; DOI: https://doi.org/10.1124/mol.111.074021
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    The LRRC26 Protein Selectively Alters the Efficacy of BK Channel Activators
    Janos Almassy and Ted Begenisich
    Molecular Pharmacology January 2012, 81 (1) 21-30; DOI: https://doi.org/10.1124/mol.111.075234
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    Diflavin Oxidoreductases Activate the Bioreductive Prodrug PR-104A under Hypoxia
    Christopher P. Guise, Maria R. Abbattista, Smitha R. Tipparaju, Neil K. Lambie, Jiechuang Su, Dan Li, William R. Wilson, Gabi U. Dachs and Adam V. Patterson
    Molecular Pharmacology January 2012, 81 (1) 31-40; DOI: https://doi.org/10.1124/mol.111.073759
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    Probe Dependence in the Allosteric Modulation of a G Protein-Coupled Receptor: Implications for Detection and Validation of Allosteric Ligand Effects
    Celine Valant, Christian C. Felder, Patrick M. Sexton and Arthur Christopoulos
    Molecular Pharmacology January 2012, 81 (1) 41-52; DOI: https://doi.org/10.1124/mol.111.074872
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    Designing Calcium Release Channel Inhibitors with Enhanced Electron Donor Properties: Stabilizing the Closed State of Ryanodine Receptor Type 1
    Yanping Ye, Daniel Yaeger, Laura J. Owen, Jorge O. Escobedo, Jialu Wang, Jeffrey D. Singer, Robert M. Strongin and Jonathan J. Abramson
    Molecular Pharmacology January 2012, 81 (1) 53-62; DOI: https://doi.org/10.1124/mol.111.074740
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    Modeling Human Cytochrome P450 2D6 Metabolism and Drug-Drug Interaction by a Novel Panel of Knockout and Humanized Mouse Lines
    Nico Scheer, Yury Kapelyukh, Jillian McEwan, Vincent Beuger, Lesley A. Stanley, Anja Rode and C. Roland Wolf
    Molecular Pharmacology January 2012, 81 (1) 63-72; DOI: https://doi.org/10.1124/mol.111.075192
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    Tyrosine Phosphorylation of the Human Serotonin Transporter: A Role in the Transporter Stability and Function
    Balasubramaniam Annamalai, Padmanabhan Mannangatti, Obulakshmi Arapulisamy, Toni S. Shippenberg, Lankupalle D. Jayanthi and Sammanda Ramamoorthy
    Molecular Pharmacology January 2012, 81 (1) 73-85; DOI: https://doi.org/10.1124/mol.111.073171
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    The Role of CYP3A4 mRNA Transcript with Shortened 3′-Untranslated Region in Hepatocyte Differentiation, Liver Development, and Response to Drug Induction
    Dan Li, Roger Gaedigk, Steven N. Hart, J. Steven Leeder and Xiao-bo Zhong
    Molecular Pharmacology January 2012, 81 (1) 86-96; DOI: https://doi.org/10.1124/mol.111.074393
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    The Activity of Human Aquaporin 1 as a cGMP-Gated Cation Channel Is Regulated by Tyrosine Phosphorylation in the Carboxyl-Terminal Domain
    Ewan M. Campbell, Dawn N. Birdsell and Andrea J. Yool
    Molecular Pharmacology January 2012, 81 (1) 97-105; DOI: https://doi.org/10.1124/mol.111.073692
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In this issue

Molecular Pharmacology: 81 (1)
Molecular Pharmacology
Vol. 81, Issue 1
1 Jan 2012
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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