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Research ArticleArticle

S1P1 Receptor Modulation with Cyclical Recovery from Lymphopenia Ameliorates Mouse Model of Multiple Sclerosis

Pedro J. Gonzalez-Cabrera, Stuart M. Cahalan, Nhan Nguyen, Gor Sarkisyan, Nora B. Leaf, Michael D. Cameron, Tomoyuki Kago and Hugh Rosen
Molecular Pharmacology February 2012, 81 (2) 166-174; DOI: https://doi.org/10.1124/mol.111.076109

Article Information

vol. 81 no. 2 166-174
DOI 
https://doi.org/10.1124/mol.111.076109
PubMed 
22031473
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received September 27, 2011
  • Accepted October 26, 2011
  • Published online January 17, 2012.

Article Versions

Copyright & Usage 
Copyright © 2012 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Pedro J. Gonzalez-Cabrera,
  2. Stuart M. Cahalan,
  3. Nhan Nguyen,
  4. Gor Sarkisyan,
  5. Nora B. Leaf,
  6. Michael D. Cameron,
  7. Tomoyuki Kago1 and
  8. Hugh Rosen
  1. Departments of Chemical Physiology (P.J.G.C., S.M.C., N.N., G.S., N.B.L., T.K., H.R.) and Immunology (S.M.C.), The Scripps Research Institute, La Jolla, California; and Department of Molecular Therapeutics, The Scripps Research Institute, Jupiter, Florida (M.D.C.)
  1. Address correspondence to:
    Dr Hugh Rosen, Department of Chemical Physiology, Scripps Research Institute, 10550 N. Torrey Pines Rd., La Jolla, CA 92037. E-mail: hrosen{at}scripps.edu

  1. P.J.G.C. and S.M.C. contributed equally to this work.

  • ↵1 Current affiliation: Kyorin Pharmaceutical Co., Pharmacology Division, Tochigi, Japan.

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EAE Efficacy of S1P1 Agonism without Sustained Lymphopenia

Pedro J. Gonzalez-Cabrera, Stuart M. Cahalan, Nhan Nguyen, Gor Sarkisyan, Nora B. Leaf, Michael D. Cameron, Tomoyuki Kago and Hugh Rosen
Molecular Pharmacology February 1, 2012, 81 (2) 166-174; DOI: https://doi.org/10.1124/mol.111.076109
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