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Molecular Pharmacology

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Research ArticleArticle

Heteromeric Canonical Transient Receptor Potential 1 and 4 Channels Play a Critical Role in Epileptiform Burst Firing and Seizure-Induced Neurodegeneration

Kevin D. Phelan, Matthew M. Mock, Oliver Kretz, U. Thaung Shwe, Maxim Kozhemyakin, L. John Greenfield, Alexander Dietrich, Lutz Birnbaumer, Marc Freichel, Veit Flockerzi and Fang Zheng
Molecular Pharmacology March 2012, 81 (3) 384-392; DOI: https://doi.org/10.1124/mol.111.075341
Kevin D. Phelan
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Matthew M. Mock
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Oliver Kretz
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U. Thaung Shwe
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Maxim Kozhemyakin
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L. John Greenfield
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Alexander Dietrich
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Lutz Birnbaumer
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Marc Freichel
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Veit Flockerzi
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Fang Zheng
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Article Information

vol. 81 no. 3 384-392
DOI 
https://doi.org/10.1124/mol.111.075341
PubMed 
22144671

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received August 19, 2011
  • Accepted December 5, 2011
  • Published online February 16, 2012.

Article Versions

  • Earlier version (December 5, 2011 - 11:44).
  • Earlier version (December 7, 2011 - 11:59).
  • You are viewing the most recent version of this article.
Copyright & Usage 
U.S. Government work not protected by U.S. copyright

Author Information

  1. Kevin D. Phelan,
  2. Matthew M. Mock,
  3. Oliver Kretz,
  4. U. Thaung Shwe,
  5. Maxim Kozhemyakin,
  6. L. John Greenfield,
  7. Alexander Dietrich,
  8. Lutz Birnbaumer,
  9. Marc Freichel,
  10. Veit Flockerzi and
  11. Fang Zheng
  1. Departments of Neurobiology and Developmental Sciences (K.D.P.), Pharmacology and Toxicology (M.M.M., U.T.S., F.Z.), and Neurology (M.K., L.J.G.), University of Arkansas for Medical Sciences, Little Rock, Arkansas; Institute of Anatomy and Cell Biology, University of Freiburg, Freiburg, Germany (O.K.); LM-University Munich, Walther-Straub-Institute for Pharmacology and Toxicology, Munich, Germany (A.D.); National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina (L.B.); and Experimentelle und Klinische Pharmakologie und Toxikologie, Medizinische Fakultät, Universität des Saarlandes, Homburg, Germany (M.F., V.F.)
  1. Address correspondence to:
    Dr. Fang Zheng, Department of Pharmacology and Toxicology, University of Arkansas for Medical Sciences, Little Rock, AR 72205. E-mail: zhengfang{at}uams.edu
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Molecular Pharmacology: 81 (3)
Molecular Pharmacology
Vol. 81, Issue 3
1 Mar 2012
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Research ArticleArticle

TRPC Channels, Epileptiform Burst Firing, and Neurodegeneration

Kevin D. Phelan, Matthew M. Mock, Oliver Kretz, U. Thaung Shwe, Maxim Kozhemyakin, L. John Greenfield, Alexander Dietrich, Lutz Birnbaumer, Marc Freichel, Veit Flockerzi and Fang Zheng
Molecular Pharmacology March 1, 2012, 81 (3) 384-392; DOI: https://doi.org/10.1124/mol.111.075341

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Research ArticleArticle

TRPC Channels, Epileptiform Burst Firing, and Neurodegeneration

Kevin D. Phelan, Matthew M. Mock, Oliver Kretz, U. Thaung Shwe, Maxim Kozhemyakin, L. John Greenfield, Alexander Dietrich, Lutz Birnbaumer, Marc Freichel, Veit Flockerzi and Fang Zheng
Molecular Pharmacology March 1, 2012, 81 (3) 384-392; DOI: https://doi.org/10.1124/mol.111.075341
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