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Molecular Pharmacology

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Research ArticleArticle

A Novel Nonribose Agonist, LUF5834, Engages Residues That Are Distinct from Those of Adenosine-Like Ligands to Activate the Adenosine A2a Receptor

J. Robert Lane, Carmen Klein Herenbrink, Gerard J. P. van Westen, Jelle A. Spoorendonk, Carsten Hoffmann and Adriaan P. IJzerman
Molecular Pharmacology March 2012, 81 (3) 475-487; DOI: https://doi.org/10.1124/mol.111.075937
J. Robert Lane
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Carmen Klein Herenbrink
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Gerard J. P. van Westen
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Jelle A. Spoorendonk
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Carsten Hoffmann
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Adriaan P. IJzerman
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Article Information

vol. 81 no. 3 475-487
DOI 
https://doi.org/10.1124/mol.111.075937
PubMed 
22188926

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received September 18, 2011
  • Accepted December 21, 2011
  • Published online February 16, 2012.

Article Versions

  • Earlier version (December 21, 2011 - 10:33).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2012 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. J. Robert Lane1,
  2. Carmen Klein Herenbrink,
  3. Gerard J. P. van Westen,
  4. Jelle A. Spoorendonk,
  5. Carsten Hoffmann and
  6. Adriaan P. IJzerman
  1. Division of Medicinal Chemistry, Leiden/Amsterdam Center for Drug Research, Leiden University, Leiden, the Netherlands (J.R.L., C.K.H., G.J.P.v.W., J.A.S., A.P.IJ.); and Department of Pharmacology and Toxicology, University of Würzburg, Würzburg, Germany (C.H.)
  1. Address correspondence to:
    J. Robert Lane, Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, 3052 Parkville, Australia. E-mail: rob.lane{at}monash.edu
  1. J.R.L. and C.K.H. contributed equally to this work.

  • ↵1 Current affiliation: Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Australia.

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Molecular Pharmacology: 81 (3)
Molecular Pharmacology
Vol. 81, Issue 3
1 Mar 2012
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Research ArticleArticle

Nonribose Agonist for Adenosine Receptors

J. Robert Lane, Carmen Klein Herenbrink, Gerard J. P. van Westen, Jelle A. Spoorendonk, Carsten Hoffmann and Adriaan P. IJzerman
Molecular Pharmacology March 1, 2012, 81 (3) 475-487; DOI: https://doi.org/10.1124/mol.111.075937

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Research ArticleArticle

Nonribose Agonist for Adenosine Receptors

J. Robert Lane, Carmen Klein Herenbrink, Gerard J. P. van Westen, Jelle A. Spoorendonk, Carsten Hoffmann and Adriaan P. IJzerman
Molecular Pharmacology March 1, 2012, 81 (3) 475-487; DOI: https://doi.org/10.1124/mol.111.075937
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