Table of Contents

Articles

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  An Inducible Cytochrome P450 3A4-Dependent Vitamin D Catabolic Pathway

  Zhican Wang, Yvonne S. Lin, Xi Emily Zheng, Tauri Senn, Takanori Hashizume, Michele Scian, Leslie J. Dickmann, Sidney D. Nelson, Thomas A. Baillie, Mary F. Hebert, David Blough, Connie L. Davis and Kenneth E. Thummel

  Molecular Pharmacology April 2012, 81 (4) 498-509; DOI: https://doi.org/10.1124/mol.111.076356
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  The Ca²⁺ Sensor Stromal Interaction Molecule 1 (STIM1) Is Necessary and Sufficient for the Store-Operated Ca²⁺ Entry Function of Transient Receptor Potential Canonical (TRPC) 1 and 4 Channels in Endothelial Cells

  Premanand C. Sundivakkam, Marc Freichel, Vandana Singh, Joseph P. Yuan, Stephen M. Vogel, Veit Flockerzi, Asrar B. Malik and Chinnaswamy Tiruppathi

  Molecular Pharmacology April 2012, 81 (4) 510-526; DOI: https://doi.org/10.1124/mol.111.074658
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  Obatoclax and Lapatinib Interact to Induce Toxic Autophagy through NOXA

  Yong Tang, Hossein A. Hamed, Nichola Cruickshanks, Paul B. Fisher, Steven Grant and Paul Dent

  Molecular Pharmacology April 2012, 81 (4) 527-540; DOI: https://doi.org/10.1124/mol.111.076851
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  Nicotine Persistently Activates Ventral Tegmental Area Dopaminergic Neurons via Nicotinic Acetylcholine Receptors Containing α4 and α6 Subunits

  Liwang Liu, Rubing Zhao-Shea, J. Michael McIntosh, Paul D. Gardner and Andrew R. Tapper

  Molecular Pharmacology April 2012, 81 (4) 541-548; DOI: https://doi.org/10.1124/mol.111.076661
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  A Superoxide-Mediated Mitogen-Activated Protein Kinase Phosphatase-1 Degradation and c-Jun NH₂-Terminal Kinase Activation Pathway for Luteolin-Induced Lung Cancer Cytotoxicity

  Lang Bai, Xiuling Xu, Qiong Wang, Shanling Xu, Wei Ju, Xia Wang, Wenshu Chen, Weiyang He, Hong Tang and Yong Lin

  Molecular Pharmacology April 2012, 81 (4) 549-555; DOI: https://doi.org/10.1124/mol.111.076653
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  cAMP-Specific Phosphodiesterases 8A and 8B, Essential Regulators of Leydig Cell Steroidogenesis

  Masami Shimizu-Albergine, Li-Chun Lisa Tsai, Enrico Patrucco and Joseph A. Beavo

  Molecular Pharmacology April 2012, 81 (4) 556-566; DOI: https://doi.org/10.1124/mol.111.076125
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  Selective, Direct Activation of High-Conductance, Calcium-Activated Potassium Channels Causes Smooth Muscle Relaxation

  Cristiano G. Ponte, Owen B. McManus, William A. Schmalhofer, Dong-Ming Shen, Ge Dai, Andra Stevenson, Sylvie Sur, Tarak Shah, Laszlo Kiss, Min Shu, James B. Doherty, Ravi Nargund, Gregory J. Kaczorowski, Guilherme Suarez-Kurtz and Maria L. Garcia

  Molecular Pharmacology April 2012, 81 (4) 567-577; DOI: https://doi.org/10.1124/mol.111.075853
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  Camptothecin Induces Apoptosis in Cancer Cells via MicroRNA-125b-Mediated Mitochondrial Pathways

  Cheng-Wu Zeng, Xing-Ju Zhang, Kang-Yu Lin, Hua Ye, Shu-Ying Feng, Hua Zhang and Yue-Qin Chen

  Molecular Pharmacology April 2012, 81 (4) 578-586; DOI: https://doi.org/10.1124/mol.111.076794
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  Mechanisms of the Inhibition of Nuclear Factor-κB by Morphine in Neuronal Cells

  Christine Börner, Volker Höllt and Jürgen Kraus

  Molecular Pharmacology April 2012, 81 (4) 587-597; DOI: https://doi.org/10.1124/mol.111.076620
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  Regulation of Breast Cancer Resistant Protein by Peroxisome Proliferator-Activated Receptor α in Human Brain Microvessel Endothelial Cells

  Md. Tozammel Hoque, Kevin R. Robillard and Reina Bendayan

  Molecular Pharmacology April 2012, 81 (4) 598-609; DOI: https://doi.org/10.1124/mol.111.076745
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  Impaired Glycinergic Synaptic Transmission and Enhanced Inflammatory Pain in Mice with Reduced Expression of Vesicular GABA Transporter (VGAT)

  Makiko Hardy Yamada, Koichi Nishikawa, Kazuhiro Kubo, Yuchio Yanagawa and Shigeru Saito

  Molecular Pharmacology April 2012, 81 (4) 610-619; DOI: https://doi.org/10.1124/mol.111.076083