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Research ArticleArticle

Lapatinib and Obatoclax Kill Tumor Cells through Blockade of ERBB1/3/4 and through Inhibition of BCL-xL and MCL-1

Nichola Cruickshanks, Hossein A. Hamed, M. Danielle Bareford, Andrew Poklepovic, Paul B. Fisher, Steven Grant and Paul Dent
Molecular Pharmacology May 2012, 81 (5) 748-758; DOI: https://doi.org/10.1124/mol.112.077586
Nichola Cruickshanks
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Hossein A. Hamed
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M. Danielle Bareford
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Andrew Poklepovic
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Paul B. Fisher
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Steven Grant
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Paul Dent
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Article Information

vol. 81 no. 5 748-758
DOI 
https://doi.org/10.1124/mol.112.077586
PubMed 
22357666

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received January 3, 2012
  • Accepted February 22, 2012
  • Published online April 16, 2012.

Article Versions

  • Earlier version (February 22, 2012 - 11:18).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2012 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Nichola Cruickshanks,
  2. Hossein A. Hamed,
  3. M. Danielle Bareford,
  4. Andrew Poklepovic,
  5. Paul B. Fisher,
  6. Steven Grant and
  7. Paul Dent
  1. Departments of Neurosurgery (N.C., H.A.H., M.D.B., P.D.), Human and Molecular Genetics (P.B.F.), and Medicine (A.P., S.G.), Virginia Commonwealth University, Richmond, Virginia
  1. Address correspondence to:
    Dr. Paul Dent, 401 College Street, Massey Cancer Center, Box 980035, Department of Neurosurgery, Virginia Commonwealth University, Richmond, VA 23298-0035. E-mail: pdent{at}vcu.edu
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Molecular Pharmacology: 81 (5)
Molecular Pharmacology
Vol. 81, Issue 5
1 May 2012
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Research ArticleArticle

Lapatinib, Obatoclax, and CNS Tumors

Nichola Cruickshanks, Hossein A. Hamed, M. Danielle Bareford, Andrew Poklepovic, Paul B. Fisher, Steven Grant and Paul Dent
Molecular Pharmacology May 1, 2012, 81 (5) 748-758; DOI: https://doi.org/10.1124/mol.112.077586

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Research ArticleArticle

Lapatinib, Obatoclax, and CNS Tumors

Nichola Cruickshanks, Hossein A. Hamed, M. Danielle Bareford, Andrew Poklepovic, Paul B. Fisher, Steven Grant and Paul Dent
Molecular Pharmacology May 1, 2012, 81 (5) 748-758; DOI: https://doi.org/10.1124/mol.112.077586
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