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Molecular Pharmacology

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Research ArticleArticle

Endomorphin-2: A Biased Agonist at the μ-Opioid Receptor

Guadalupe Rivero, Javier Llorente, Jamie McPherson, Alex Cooke, Stuart J. Mundell, Craig A. McArdle, Elizabeth M. Rosethorne, Steven J. Charlton, Cornelius Krasel, Christopher P. Bailey, Graeme Henderson and Eamonn Kelly
Molecular Pharmacology August 2012, 82 (2) 178-188; DOI: https://doi.org/10.1124/mol.112.078659
Guadalupe Rivero
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Javier Llorente
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Jamie McPherson
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Alex Cooke
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Stuart J. Mundell
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Craig A. McArdle
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Elizabeth M. Rosethorne
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Steven J. Charlton
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Cornelius Krasel
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Christopher P. Bailey
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Graeme Henderson
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Eamonn Kelly
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Article Information

vol. 82 no. 2 178-188
DOI 
https://doi.org/10.1124/mol.112.078659
PubMed 
22553358

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received March 15, 2012
  • Accepted May 2, 2012
  • Published online July 16, 2012.

Article Versions

  • Earlier version (May 2, 2012 - 10:05).
  • Earlier version (May 3, 2012 - 08:20).
  • Earlier version (May 8, 2012 - 09:01).
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Copyright & Usage 
Copyright © 2012 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Guadalupe Rivero,
  2. Javier Llorente,
  3. Jamie McPherson,
  4. Alex Cooke,
  5. Stuart J. Mundell,
  6. Craig A. McArdle,
  7. Elizabeth M. Rosethorne,
  8. Steven J. Charlton,
  9. Cornelius Krasel,
  10. Christopher P. Bailey,
  11. Graeme Henderson and
  12. Eamonn Kelly
  1. School of Physiology and Pharmacology (G.R., J.L., J.M., A.C., S.J.M., G.H., E.K.) and School of Clinical Sciences, University of Bristol, Bristol, United Kingdom (C.A.M.); Novartis Institutes for Biomedical Research, Horsham, West Sussex, United Kingdom (E.M.R., S.J.C.); Institute for Pharmacology and Clinical Pharmacy, Marburg, Germany (C.K.); and Department of Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom (C.P.B.)
  1. Address correspondence to:
    Dr. Eamonn Kelly, School of Physiology and Pharmacology, University of Bristol, University Walk, Bristol BS8 1TD, UK. E-mail: e.kelly{at}bristol.ac.uk
  1. G.R. and J.L. contributed equally to this work.

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Molecular Pharmacology: 82 (2)
Molecular Pharmacology
Vol. 82, Issue 2
1 Aug 2012
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Research ArticleArticle

Endomorphin-2 Is an Arrestin-Biased Agonist

Guadalupe Rivero, Javier Llorente, Jamie McPherson, Alex Cooke, Stuart J. Mundell, Craig A. McArdle, Elizabeth M. Rosethorne, Steven J. Charlton, Cornelius Krasel, Christopher P. Bailey, Graeme Henderson and Eamonn Kelly
Molecular Pharmacology August 1, 2012, 82 (2) 178-188; DOI: https://doi.org/10.1124/mol.112.078659

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Research ArticleArticle

Endomorphin-2 Is an Arrestin-Biased Agonist

Guadalupe Rivero, Javier Llorente, Jamie McPherson, Alex Cooke, Stuart J. Mundell, Craig A. McArdle, Elizabeth M. Rosethorne, Steven J. Charlton, Cornelius Krasel, Christopher P. Bailey, Graeme Henderson and Eamonn Kelly
Molecular Pharmacology August 1, 2012, 82 (2) 178-188; DOI: https://doi.org/10.1124/mol.112.078659
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