Department of Pharmacology and Toxicology, Karl-Franzens-Universität Graz, Graz, Austria (K.S., A.N., B.K., A.C.F.G., B.M.); Division of Biological Chemistry, Biocentre, Innsbruck Medical University, Innsbruck, Austria (E.R.W.); and Pharma Research Centre, Bayer HealthCare, Wuppertal Germany (J.-P.S.)

Department of Pharmacology and Toxicology, Karl-Franzens-Universität Graz, Graz, Austria (K.S., A.N., B.K., A.C.F.G., B.M.); Division of Biological Chemistry, Biocentre, Innsbruck Medical University, Innsbruck, Austria (E.R.W.); and Pharma Research Centre, Bayer HealthCare, Wuppertal Germany (J.-P.S.)

Department of Pharmacology and Toxicology, Karl-Franzens-Universität Graz, Graz, Austria (K.S., A.N., B.K., A.C.F.G., B.M.); Division of Biological Chemistry, Biocentre, Innsbruck Medical University, Innsbruck, Austria (E.R.W.); and Pharma Research Centre, Bayer HealthCare, Wuppertal Germany (J.-P.S.)

Department of Pharmacology and Toxicology, Karl-Franzens-Universität Graz, Graz, Austria (K.S., A.N., B.K., A.C.F.G., B.M.); Division of Biological Chemistry, Biocentre, Innsbruck Medical University, Innsbruck, Austria (E.R.W.); and Pharma Research Centre, Bayer HealthCare, Wuppertal Germany (J.-P.S.)

Department of Pharmacology and Toxicology, Karl-Franzens-Universität Graz, Graz, Austria (K.S., A.N., B.K., A.C.F.G., B.M.); Division of Biological Chemistry, Biocentre, Innsbruck Medical University, Innsbruck, Austria (E.R.W.); and Pharma Research Centre, Bayer HealthCare, Wuppertal Germany (J.-P.S.)

Department of Pharmacology and Toxicology, Karl-Franzens-Universität Graz, Graz, Austria (K.S., A.N., B.K., A.C.F.G., B.M.); Division of Biological Chemistry, Biocentre, Innsbruck Medical University, Innsbruck, Austria (E.R.W.); and Pharma Research Centre, Bayer HealthCare, Wuppertal Germany (J.-P.S.)

Department of Pharmacology and Toxicology, Karl-Franzens-Universität Graz, Graz, Austria (K.S., A.N., B.K., A.C.F.G., B.M.); Division of Biological Chemistry, Biocentre, Innsbruck Medical University, Innsbruck, Austria (E.R.W.); and Pharma Research Centre, Bayer HealthCare, Wuppertal Germany (J.-P.S.)