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Index by author

October 01, 2012; Volume 82,Issue 4

A

  1. Al-Abed, Yousef

    1. Therapeutic Potential of Nitric Oxide-Modified Drugs in Colon Cancer Cells
      Marija Mojic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Djordje Miljkovic, Stanislava Stosic-Grujicic, Marija Stankovic, Katia Mangano, Salvatore Travali, Marco Donia, Paolo Fagone, Mai-Britt Zocca, Yousef Al-Abed, James A. McCubrey and Ferdinando Nicoletti
      Molecular Pharmacology October 2012, 82 (4) 700-710; DOI: https://doi.org/10.1124/mol.112.077842

  2. Amunom, I.

    1. Activator Protein-1 Regulation of Murine Aldehyde Dehydrogenase 1a1
      N. L. Makia, I. Amunom, K. C. Falkner, D. J. Conklin, S. Surapureddi, J. A. Goldstein and R. A. Prough
      Molecular Pharmacology October 2012, 82 (4) 601-613; DOI: https://doi.org/10.1124/mol.112.078147

  3. An, Gang

    1. Increasing Human Th17 Differentiation through Activation of Orphan Nuclear Receptor Retinoid Acid-Related Orphan Receptor γ (RORγ) by a Class of Aryl Amide Compounds
      Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
      Molecular Pharmacology October 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667

  4. Anderson, Marc

    1. Sustained Activation of N-Methyl-d-Aspartate Receptors in Podoctyes Leads to Oxidative Stress, Mobilization of Transient Receptor Potential Canonical 6 Channels, Nuclear Factor of Activated T Cells Activation, and Apoptotic Cell Death
      Eun Young Kim, Marc Anderson and Stuart E. Dryer
      Molecular Pharmacology October 2012, 82 (4) 728-737; DOI: https://doi.org/10.1124/mol.112.079376

B

  1. Bair, Thomas

    1. RNA Aptamer-Based Functional Ligands of the Neurotrophin Receptor, TrkB
      Yang Zhong Huang, Frank J. Hernandez, Bin Gu, Katie R. Stockdale, Kishore Nanapaneni, Todd E. Scheetz, Mark A. Behlke, Andrew S. Peek, Thomas Bair, Paloma H. Giangrande and James O. McNamara
      Molecular Pharmacology October 2012, 82 (4) 623-635; DOI: https://doi.org/10.1124/mol.112.078220

  2. Banerji, Asoke

    1. Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9
      Athira Omanakuttan, Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Nanjan Pandurangan, Rebu K. Varghese, Geetha B. Kumar, John A. Tainer, Asoke Banerji, J. Jefferson P. Perry and Bipin G. Nair
      Molecular Pharmacology October 2012, 82 (4) 614-622; DOI: https://doi.org/10.1124/mol.112.079020

  3. Behlke, Mark A.

    1. RNA Aptamer-Based Functional Ligands of the Neurotrophin Receptor, TrkB
      Yang Zhong Huang, Frank J. Hernandez, Bin Gu, Katie R. Stockdale, Kishore Nanapaneni, Todd E. Scheetz, Mark A. Behlke, Andrew S. Peek, Thomas Bair, Paloma H. Giangrande and James O. McNamara
      Molecular Pharmacology October 2012, 82 (4) 623-635; DOI: https://doi.org/10.1124/mol.112.078220

  4. Beijnen, Jos H.

    1. P-Glycoprotein, Multidrug-Resistance Associated Protein 2, Cyp3a, and Carboxylesterase Affect the Oral Availability and Metabolism of Vinorelbine
      Jurjen S. Lagas, Carola W. N. Damen, Robert A. B. van Waterschoot, Dilek Iusuf, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology October 2012, 82 (4) 636-644; DOI: https://doi.org/10.1124/mol.111.077099

  5. Beissner, Mirko

    1. Efficient Binding of 4/7 α-Conotoxins to Nicotinic α4β2 Receptors Is Prevented by Arg185 and Pro195 in the α4 Subunit
      Mirko Beissner, Sébastien Dutertre, Rudolf Schemm, Timm Danker, Annett Sporning, Helmut Grubmüller and Annette Nicke
      Molecular Pharmacology October 2012, 82 (4) 711-718; DOI: https://doi.org/10.1124/mol.112.078683

  6. Bose, Chinchu

    1. Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9
      Athira Omanakuttan, Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Nanjan Pandurangan, Rebu K. Varghese, Geetha B. Kumar, John A. Tainer, Asoke Banerji, J. Jefferson P. Perry and Bipin G. Nair
      Molecular Pharmacology October 2012, 82 (4) 614-622; DOI: https://doi.org/10.1124/mol.112.079020

  7. Bragg, Laricia

    1. Activation of Trimeric P2X2 Receptors by Fewer than Three ATP Molecules
      Olga Stelmashenko, Ulyana Lalo, Yue Yang, Laricia Bragg, R. Alan North and Vincent Compan
      Molecular Pharmacology October 2012, 82 (4) 760-766; DOI: https://doi.org/10.1124/mol.112.080903

  8. Bukhtiyarov, Yuri

    1. Regulation of Sphingomyelin Phosphodiesterase Acid-Like 3A Gene (SMPDL3A) by Liver X Receptors
      Paul B. Noto, Yuri Bukhtiyarov, Meng Shi, Brian M. McKeever, Gerard M. McGeehan and Deepak S. Lala
      Molecular Pharmacology October 2012, 82 (4) 719-727; DOI: https://doi.org/10.1124/mol.112.078865

C

  1. Cherian, Christina

    1. Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology October 2012, 82 (4) 591-600; DOI: https://doi.org/10.1124/mol.112.079004

  2. Compan, Vincent

    1. Activation of Trimeric P2X2 Receptors by Fewer than Three ATP Molecules
      Olga Stelmashenko, Ulyana Lalo, Yue Yang, Laricia Bragg, R. Alan North and Vincent Compan
      Molecular Pharmacology October 2012, 82 (4) 760-766; DOI: https://doi.org/10.1124/mol.112.080903

  3. Conklin, D. J.

    1. Activator Protein-1 Regulation of Murine Aldehyde Dehydrogenase 1a1
      N. L. Makia, I. Amunom, K. C. Falkner, D. J. Conklin, S. Surapureddi, J. A. Goldstein and R. A. Prough
      Molecular Pharmacology October 2012, 82 (4) 601-613; DOI: https://doi.org/10.1124/mol.112.078147

D

  1. Damen, Carola W. N.

    1. P-Glycoprotein, Multidrug-Resistance Associated Protein 2, Cyp3a, and Carboxylesterase Affect the Oral Availability and Metabolism of Vinorelbine
      Jurjen S. Lagas, Carola W. N. Damen, Robert A. B. van Waterschoot, Dilek Iusuf, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology October 2012, 82 (4) 636-644; DOI: https://doi.org/10.1124/mol.111.077099

  2. Danker, Timm

    1. Efficient Binding of 4/7 α-Conotoxins to Nicotinic α4β2 Receptors Is Prevented by Arg185 and Pro195 in the α4 Subunit
      Mirko Beissner, Sébastien Dutertre, Rudolf Schemm, Timm Danker, Annett Sporning, Helmut Grubmüller and Annette Nicke
      Molecular Pharmacology October 2012, 82 (4) 711-718; DOI: https://doi.org/10.1124/mol.112.078683

  3. Daskalopoulos, Evangelos P.

    1. D2-Dopaminergic Receptor-Linked Pathways: Critical Regulators of CYP3A, CYP2C, and CYP2D
      Evangelos P. Daskalopoulos, Matti A. Lang, Marios Marselos, Foteini Malliou and Maria Konstandi
      Molecular Pharmacology October 2012, 82 (4) 668-678; DOI: https://doi.org/10.1124/mol.112.078709

  4. Desmoulin, Sita Kugel

    1. Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology October 2012, 82 (4) 591-600; DOI: https://doi.org/10.1124/mol.112.079004

  5. Donia, Marco

    1. Therapeutic Potential of Nitric Oxide-Modified Drugs in Colon Cancer Cells
      Marija Mojic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Djordje Miljkovic, Stanislava Stosic-Grujicic, Marija Stankovic, Katia Mangano, Salvatore Travali, Marco Donia, Paolo Fagone, Mai-Britt Zocca, Yousef Al-Abed, James A. McCubrey and Ferdinando Nicoletti
      Molecular Pharmacology October 2012, 82 (4) 700-710; DOI: https://doi.org/10.1124/mol.112.077842

  6. Dores, Michael R.

    1. Ubiquitination of G Protein-Coupled Receptors: Functional Implications and Drug Discovery
      Michael R. Dores and JoAnn Trejo
      Molecular Pharmacology October 2012, 82 (4) 563-570; DOI: https://doi.org/10.1124/mol.112.079418

  7. Dryer, Stuart E.

    1. Sustained Activation of N-Methyl-d-Aspartate Receptors in Podoctyes Leads to Oxidative Stress, Mobilization of Transient Receptor Potential Canonical 6 Channels, Nuclear Factor of Activated T Cells Activation, and Apoptotic Cell Death
      Eun Young Kim, Marc Anderson and Stuart E. Dryer
      Molecular Pharmacology October 2012, 82 (4) 728-737; DOI: https://doi.org/10.1124/mol.112.079376

  8. Dufouil, Mikael

    1. Synthesis of Selective Agonists for the α7 Nicotinic Acetylcholine Receptor with In Situ Click-Chemistry on Acetylcholine-Binding Protein Templates
      John G. Yamauchi, Kimberly Gomez, Neil Grimster, Mikael Dufouil, Ákos Nemecz, Joseph R. Fotsing, Kwok-Yiu Ho, Todd T. Talley, K. Barry Sharpless, Valery V. Fokin and Palmer Taylor
      Molecular Pharmacology October 2012, 82 (4) 687-699; DOI: https://doi.org/10.1124/mol.112.080291

  9. Dutertre, Sébastien

    1. Efficient Binding of 4/7 α-Conotoxins to Nicotinic α4β2 Receptors Is Prevented by Arg185 and Pro195 in the α4 Subunit
      Mirko Beissner, Sébastien Dutertre, Rudolf Schemm, Timm Danker, Annett Sporning, Helmut Grubmüller and Annette Nicke
      Molecular Pharmacology October 2012, 82 (4) 711-718; DOI: https://doi.org/10.1124/mol.112.078683

E

  1. Eipper, Betty A.

    1. A Role for Kalirin in the Response of Rat Medium Spiny Neurons to Cocaine
      Xin-Ming Ma, Jian-ping Huang, Xiaonan Xin, Yan Yan, Richard E. Mains and Betty A. Eipper
      Molecular Pharmacology October 2012, 82 (4) 738-745; DOI: https://doi.org/10.1124/mol.112.080044

F

  1. Fagone, Paolo

    1. Therapeutic Potential of Nitric Oxide-Modified Drugs in Colon Cancer Cells
      Marija Mojic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Djordje Miljkovic, Stanislava Stosic-Grujicic, Marija Stankovic, Katia Mangano, Salvatore Travali, Marco Donia, Paolo Fagone, Mai-Britt Zocca, Yousef Al-Abed, James A. McCubrey and Ferdinando Nicoletti
      Molecular Pharmacology October 2012, 82 (4) 700-710; DOI: https://doi.org/10.1124/mol.112.077842

  2. Falkner, K. C.

    1. Activator Protein-1 Regulation of Murine Aldehyde Dehydrogenase 1a1
      N. L. Makia, I. Amunom, K. C. Falkner, D. J. Conklin, S. Surapureddi, J. A. Goldstein and R. A. Prough
      Molecular Pharmacology October 2012, 82 (4) 601-613; DOI: https://doi.org/10.1124/mol.112.078147

  3. Fang, Leiping

    1. Increasing Human Th17 Differentiation through Activation of Orphan Nuclear Receptor Retinoid Acid-Related Orphan Receptor γ (RORγ) by a Class of Aryl Amide Compounds
      Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
      Molecular Pharmacology October 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667

  4. Fisher, Gregory W.

    1. Discovery of Regulators of Receptor Internalization with High-Throughput Flow Cytometry
      Yang Wu, Phillip H. Tapia, Gregory W. Fisher, Peter C. Simons, J. Jacob Strouse, Terry Foutz, Alan S. Waggoner, Jonathan Jarvik and Larry A. Sklar
      Molecular Pharmacology October 2012, 82 (4) 645-657; DOI: https://doi.org/10.1124/mol.112.079897

  5. Fokin, Valery V.

    1. Synthesis of Selective Agonists for the α7 Nicotinic Acetylcholine Receptor with In Situ Click-Chemistry on Acetylcholine-Binding Protein Templates
      John G. Yamauchi, Kimberly Gomez, Neil Grimster, Mikael Dufouil, Ákos Nemecz, Joseph R. Fotsing, Kwok-Yiu Ho, Todd T. Talley, K. Barry Sharpless, Valery V. Fokin and Palmer Taylor
      Molecular Pharmacology October 2012, 82 (4) 687-699; DOI: https://doi.org/10.1124/mol.112.080291

  6. Fotsing, Joseph R.

    1. Synthesis of Selective Agonists for the α7 Nicotinic Acetylcholine Receptor with In Situ Click-Chemistry on Acetylcholine-Binding Protein Templates
      John G. Yamauchi, Kimberly Gomez, Neil Grimster, Mikael Dufouil, Ákos Nemecz, Joseph R. Fotsing, Kwok-Yiu Ho, Todd T. Talley, K. Barry Sharpless, Valery V. Fokin and Palmer Taylor
      Molecular Pharmacology October 2012, 82 (4) 687-699; DOI: https://doi.org/10.1124/mol.112.080291

  7. Foutz, Terry

    1. Discovery of Regulators of Receptor Internalization with High-Throughput Flow Cytometry
      Yang Wu, Phillip H. Tapia, Gregory W. Fisher, Peter C. Simons, J. Jacob Strouse, Terry Foutz, Alan S. Waggoner, Jonathan Jarvik and Larry A. Sklar
      Molecular Pharmacology October 2012, 82 (4) 645-657; DOI: https://doi.org/10.1124/mol.112.079897

G

  1. Gangjee, Aleem

    1. Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology October 2012, 82 (4) 591-600; DOI: https://doi.org/10.1124/mol.112.079004

  2. Giangrande, Paloma H.

    1. RNA Aptamer-Based Functional Ligands of the Neurotrophin Receptor, TrkB
      Yang Zhong Huang, Frank J. Hernandez, Bin Gu, Katie R. Stockdale, Kishore Nanapaneni, Todd E. Scheetz, Mark A. Behlke, Andrew S. Peek, Thomas Bair, Paloma H. Giangrande and James O. McNamara
      Molecular Pharmacology October 2012, 82 (4) 623-635; DOI: https://doi.org/10.1124/mol.112.078220

  3. Goldstein, J. A.

    1. Activator Protein-1 Regulation of Murine Aldehyde Dehydrogenase 1a1
      N. L. Makia, I. Amunom, K. C. Falkner, D. J. Conklin, S. Surapureddi, J. A. Goldstein and R. A. Prough
      Molecular Pharmacology October 2012, 82 (4) 601-613; DOI: https://doi.org/10.1124/mol.112.078147

  4. Gomez, Kimberly

    1. Synthesis of Selective Agonists for the α7 Nicotinic Acetylcholine Receptor with In Situ Click-Chemistry on Acetylcholine-Binding Protein Templates
      John G. Yamauchi, Kimberly Gomez, Neil Grimster, Mikael Dufouil, Ákos Nemecz, Joseph R. Fotsing, Kwok-Yiu Ho, Todd T. Talley, K. Barry Sharpless, Valery V. Fokin and Palmer Taylor
      Molecular Pharmacology October 2012, 82 (4) 687-699; DOI: https://doi.org/10.1124/mol.112.080291

  5. Gomora, Juan C.

    1. Block of Human CaV3 Channels by the Diuretic Amiloride
      Osbaldo Lopez-Charcas, Manuel Rivera and Juan C. Gomora
      Molecular Pharmacology October 2012, 82 (4) 658-667; DOI: https://doi.org/10.1124/mol.112.078923

  6. Grimster, Neil

    1. Synthesis of Selective Agonists for the α7 Nicotinic Acetylcholine Receptor with In Situ Click-Chemistry on Acetylcholine-Binding Protein Templates
      John G. Yamauchi, Kimberly Gomez, Neil Grimster, Mikael Dufouil, Ákos Nemecz, Joseph R. Fotsing, Kwok-Yiu Ho, Todd T. Talley, K. Barry Sharpless, Valery V. Fokin and Palmer Taylor
      Molecular Pharmacology October 2012, 82 (4) 687-699; DOI: https://doi.org/10.1124/mol.112.080291

  7. Grubmüller, Helmut

    1. Efficient Binding of 4/7 α-Conotoxins to Nicotinic α4β2 Receptors Is Prevented by Arg185 and Pro195 in the α4 Subunit
      Mirko Beissner, Sébastien Dutertre, Rudolf Schemm, Timm Danker, Annett Sporning, Helmut Grubmüller and Annette Nicke
      Molecular Pharmacology October 2012, 82 (4) 711-718; DOI: https://doi.org/10.1124/mol.112.078683

  8. Gu, Bin

    1. RNA Aptamer-Based Functional Ligands of the Neurotrophin Receptor, TrkB
      Yang Zhong Huang, Frank J. Hernandez, Bin Gu, Katie R. Stockdale, Kishore Nanapaneni, Todd E. Scheetz, Mark A. Behlke, Andrew S. Peek, Thomas Bair, Paloma H. Giangrande and James O. McNamara
      Molecular Pharmacology October 2012, 82 (4) 623-635; DOI: https://doi.org/10.1124/mol.112.078220

H

  1. Hanenberg, Helmut

    1. CYP4V2 in Bietti's Crystalline Dystrophy: Ocular Localization, Metabolism of ω-3-Polyunsaturated Fatty Acids, and Functional Deficit of the p.H331P Variant
      Mariko Nakano, Edward J. Kelly, Constanze Wiek, Helmut Hanenberg and Allan E. Rettie
      Molecular Pharmacology October 2012, 82 (4) 679-686; DOI: https://doi.org/10.1124/mol.112.080085

  2. Harris, Rodney M.

    1. Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9
      Athira Omanakuttan, Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Nanjan Pandurangan, Rebu K. Varghese, Geetha B. Kumar, John A. Tainer, Asoke Banerji, J. Jefferson P. Perry and Bipin G. Nair
      Molecular Pharmacology October 2012, 82 (4) 614-622; DOI: https://doi.org/10.1124/mol.112.079020

  3. Hernandez, Frank J.

    1. RNA Aptamer-Based Functional Ligands of the Neurotrophin Receptor, TrkB
      Yang Zhong Huang, Frank J. Hernandez, Bin Gu, Katie R. Stockdale, Kishore Nanapaneni, Todd E. Scheetz, Mark A. Behlke, Andrew S. Peek, Thomas Bair, Paloma H. Giangrande and James O. McNamara
      Molecular Pharmacology October 2012, 82 (4) 623-635; DOI: https://doi.org/10.1124/mol.112.078220

  4. Ho, Kwok-Yiu

    1. Synthesis of Selective Agonists for the α7 Nicotinic Acetylcholine Receptor with In Situ Click-Chemistry on Acetylcholine-Binding Protein Templates
      John G. Yamauchi, Kimberly Gomez, Neil Grimster, Mikael Dufouil, Ákos Nemecz, Joseph R. Fotsing, Kwok-Yiu Ho, Todd T. Talley, K. Barry Sharpless, Valery V. Fokin and Palmer Taylor
      Molecular Pharmacology October 2012, 82 (4) 687-699; DOI: https://doi.org/10.1124/mol.112.080291

  5. Hou, Zhanjun

    1. Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology October 2012, 82 (4) 591-600; DOI: https://doi.org/10.1124/mol.112.079004

  6. Huang, Jian-ping

    1. A Role for Kalirin in the Response of Rat Medium Spiny Neurons to Cocaine
      Xin-Ming Ma, Jian-ping Huang, Xiaonan Xin, Yan Yan, Richard E. Mains and Betty A. Eipper
      Molecular Pharmacology October 2012, 82 (4) 738-745; DOI: https://doi.org/10.1124/mol.112.080044

  7. Huang, Yang Zhong

    1. RNA Aptamer-Based Functional Ligands of the Neurotrophin Receptor, TrkB
      Yang Zhong Huang, Frank J. Hernandez, Bin Gu, Katie R. Stockdale, Kishore Nanapaneni, Todd E. Scheetz, Mark A. Behlke, Andrew S. Peek, Thomas Bair, Paloma H. Giangrande and James O. McNamara
      Molecular Pharmacology October 2012, 82 (4) 623-635; DOI: https://doi.org/10.1124/mol.112.078220

  8. Huehls, Amelia M.

    1. Identification of DNA Repair Pathways That Affect the Survival of Ovarian Cancer Cells Treated with a Poly(ADP-Ribose) Polymerase Inhibitor in a Novel Drug Combination
      Amelia M. Huehls, Jill M. Wagner, Catherine J. Huntoon and Larry M. Karnitz
      Molecular Pharmacology October 2012, 82 (4) 767-776; DOI: https://doi.org/10.1124/mol.112.080614

  9. Huntoon, Catherine J.

    1. Identification of DNA Repair Pathways That Affect the Survival of Ovarian Cancer Cells Treated with a Poly(ADP-Ribose) Polymerase Inhibitor in a Novel Drug Combination
      Amelia M. Huehls, Jill M. Wagner, Catherine J. Huntoon and Larry M. Karnitz
      Molecular Pharmacology October 2012, 82 (4) 767-776; DOI: https://doi.org/10.1124/mol.112.080614

I

  1. Iusuf, Dilek

    1. P-Glycoprotein, Multidrug-Resistance Associated Protein 2, Cyp3a, and Carboxylesterase Affect the Oral Availability and Metabolism of Vinorelbine
      Jurjen S. Lagas, Carola W. N. Damen, Robert A. B. van Waterschoot, Dilek Iusuf, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology October 2012, 82 (4) 636-644; DOI: https://doi.org/10.1124/mol.111.077099

J

  1. Jarvik, Jonathan

    1. Discovery of Regulators of Receptor Internalization with High-Throughput Flow Cytometry
      Yang Wu, Phillip H. Tapia, Gregory W. Fisher, Peter C. Simons, J. Jacob Strouse, Terry Foutz, Alan S. Waggoner, Jonathan Jarvik and Larry A. Sklar
      Molecular Pharmacology October 2012, 82 (4) 645-657; DOI: https://doi.org/10.1124/mol.112.079897

K

  1. Karnitz, Larry M.

    1. Identification of DNA Repair Pathways That Affect the Survival of Ovarian Cancer Cells Treated with a Poly(ADP-Ribose) Polymerase Inhibitor in a Novel Drug Combination
      Amelia M. Huehls, Jill M. Wagner, Catherine J. Huntoon and Larry M. Karnitz
      Molecular Pharmacology October 2012, 82 (4) 767-776; DOI: https://doi.org/10.1124/mol.112.080614

  2. Kelly, Edward J.

    1. CYP4V2 in Bietti's Crystalline Dystrophy: Ocular Localization, Metabolism of ω-3-Polyunsaturated Fatty Acids, and Functional Deficit of the p.H331P Variant
      Mariko Nakano, Edward J. Kelly, Constanze Wiek, Helmut Hanenberg and Allan E. Rettie
      Molecular Pharmacology October 2012, 82 (4) 679-686; DOI: https://doi.org/10.1124/mol.112.080085

  3. Kenakin, Terry

    1. Casting a Wider Net: Whole-Cell Assays to Capture Varied and Biased Signaling
      Terry Kenakin
      Molecular Pharmacology October 2012, 82 (4) 571-574; DOI: https://doi.org/10.1124/mol.112.081117

  4. Kim, Eun Young

    1. Sustained Activation of N-Methyl-d-Aspartate Receptors in Podoctyes Leads to Oxidative Stress, Mobilization of Transient Receptor Potential Canonical 6 Channels, Nuclear Factor of Activated T Cells Activation, and Apoptotic Cell Death
      Eun Young Kim, Marc Anderson and Stuart E. Dryer
      Molecular Pharmacology October 2012, 82 (4) 728-737; DOI: https://doi.org/10.1124/mol.112.079376

  5. Kimbrell, Matthew R.

    1. Intrinsically Low Open Probability of α7 Nicotinic Acetylcholine Receptors Can Be Overcome by Positive Allosteric Modulation and Serum Factors Leading to the Generation of Excitotoxic Currents at Physiological Temperatures
      Dustin K. Williams, Can Peng, Matthew R. Kimbrell and Roger L. Papke
      Molecular Pharmacology October 2012, 82 (4) 746-759; DOI: https://doi.org/10.1124/mol.112.080317

  6. Konstandi, Maria

    1. D2-Dopaminergic Receptor-Linked Pathways: Critical Regulators of CYP3A, CYP2C, and CYP2D
      Evangelos P. Daskalopoulos, Matti A. Lang, Marios Marselos, Foteini Malliou and Maria Konstandi
      Molecular Pharmacology October 2012, 82 (4) 668-678; DOI: https://doi.org/10.1124/mol.112.078709

  7. Kumar, Geetha B.

    1. Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9
      Athira Omanakuttan, Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Nanjan Pandurangan, Rebu K. Varghese, Geetha B. Kumar, John A. Tainer, Asoke Banerji, J. Jefferson P. Perry and Bipin G. Nair
      Molecular Pharmacology October 2012, 82 (4) 614-622; DOI: https://doi.org/10.1124/mol.112.079020

  8. Kushner, Juiwanna

    1. Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology October 2012, 82 (4) 591-600; DOI: https://doi.org/10.1124/mol.112.079004

L

  1. Lagas, Jurjen S.

    1. P-Glycoprotein, Multidrug-Resistance Associated Protein 2, Cyp3a, and Carboxylesterase Affect the Oral Availability and Metabolism of Vinorelbine
      Jurjen S. Lagas, Carola W. N. Damen, Robert A. B. van Waterschoot, Dilek Iusuf, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology October 2012, 82 (4) 636-644; DOI: https://doi.org/10.1124/mol.111.077099

  2. Lala, Deepak S.

    1. Regulation of Sphingomyelin Phosphodiesterase Acid-Like 3A Gene (SMPDL3A) by Liver X Receptors
      Paul B. Noto, Yuri Bukhtiyarov, Meng Shi, Brian M. McKeever, Gerard M. McGeehan and Deepak S. Lala
      Molecular Pharmacology October 2012, 82 (4) 719-727; DOI: https://doi.org/10.1124/mol.112.078865

  3. Lalo, Ulyana

    1. Activation of Trimeric P2X2 Receptors by Fewer than Three ATP Molecules
      Olga Stelmashenko, Ulyana Lalo, Yue Yang, Laricia Bragg, R. Alan North and Vincent Compan
      Molecular Pharmacology October 2012, 82 (4) 760-766; DOI: https://doi.org/10.1124/mol.112.080903

  4. Lang, Matti A.

    1. D2-Dopaminergic Receptor-Linked Pathways: Critical Regulators of CYP3A, CYP2C, and CYP2D
      Evangelos P. Daskalopoulos, Matti A. Lang, Marios Marselos, Foteini Malliou and Maria Konstandi
      Molecular Pharmacology October 2012, 82 (4) 668-678; DOI: https://doi.org/10.1124/mol.112.078709

  5. Leung, Stewart

    1. Increasing Human Th17 Differentiation through Activation of Orphan Nuclear Receptor Retinoid Acid-Related Orphan Receptor γ (RORγ) by a Class of Aryl Amide Compounds
      Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
      Molecular Pharmacology October 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667

  6. Li, Yuan

    1. Increasing Human Th17 Differentiation through Activation of Orphan Nuclear Receptor Retinoid Acid-Related Orphan Receptor γ (RORγ) by a Class of Aryl Amide Compounds
      Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
      Molecular Pharmacology October 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667

  7. Lopez-Charcas, Osbaldo

    1. Block of Human CaV3 Channels by the Diuretic Amiloride
      Osbaldo Lopez-Charcas, Manuel Rivera and Juan C. Gomora
      Molecular Pharmacology October 2012, 82 (4) 658-667; DOI: https://doi.org/10.1124/mol.112.078923

M

  1. Ma, Xin-Ming

    1. A Role for Kalirin in the Response of Rat Medium Spiny Neurons to Cocaine
      Xin-Ming Ma, Jian-ping Huang, Xiaonan Xin, Yan Yan, Richard E. Mains and Betty A. Eipper
      Molecular Pharmacology October 2012, 82 (4) 738-745; DOI: https://doi.org/10.1124/mol.112.080044

  2. Mains, Richard E.

    1. A Role for Kalirin in the Response of Rat Medium Spiny Neurons to Cocaine
      Xin-Ming Ma, Jian-ping Huang, Xiaonan Xin, Yan Yan, Richard E. Mains and Betty A. Eipper
      Molecular Pharmacology October 2012, 82 (4) 738-745; DOI: https://doi.org/10.1124/mol.112.080044

  3. Makia, N. L.

    1. Activator Protein-1 Regulation of Murine Aldehyde Dehydrogenase 1a1
      N. L. Makia, I. Amunom, K. C. Falkner, D. J. Conklin, S. Surapureddi, J. A. Goldstein and R. A. Prough
      Molecular Pharmacology October 2012, 82 (4) 601-613; DOI: https://doi.org/10.1124/mol.112.078147

  4. Maksimovic-Ivanic, Danijela

    1. Therapeutic Potential of Nitric Oxide-Modified Drugs in Colon Cancer Cells
      Marija Mojic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Djordje Miljkovic, Stanislava Stosic-Grujicic, Marija Stankovic, Katia Mangano, Salvatore Travali, Marco Donia, Paolo Fagone, Mai-Britt Zocca, Yousef Al-Abed, James A. McCubrey and Ferdinando Nicoletti
      Molecular Pharmacology October 2012, 82 (4) 700-710; DOI: https://doi.org/10.1124/mol.112.077842

  5. Malliou, Foteini

    1. D2-Dopaminergic Receptor-Linked Pathways: Critical Regulators of CYP3A, CYP2C, and CYP2D
      Evangelos P. Daskalopoulos, Matti A. Lang, Marios Marselos, Foteini Malliou and Maria Konstandi
      Molecular Pharmacology October 2012, 82 (4) 668-678; DOI: https://doi.org/10.1124/mol.112.078709

  6. Mangano, Katia

    1. Therapeutic Potential of Nitric Oxide-Modified Drugs in Colon Cancer Cells
      Marija Mojic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Djordje Miljkovic, Stanislava Stosic-Grujicic, Marija Stankovic, Katia Mangano, Salvatore Travali, Marco Donia, Paolo Fagone, Mai-Britt Zocca, Yousef Al-Abed, James A. McCubrey and Ferdinando Nicoletti
      Molecular Pharmacology October 2012, 82 (4) 700-710; DOI: https://doi.org/10.1124/mol.112.077842

  7. Marselos, Marios

    1. D2-Dopaminergic Receptor-Linked Pathways: Critical Regulators of CYP3A, CYP2C, and CYP2D
      Evangelos P. Daskalopoulos, Matti A. Lang, Marios Marselos, Foteini Malliou and Maria Konstandi
      Molecular Pharmacology October 2012, 82 (4) 668-678; DOI: https://doi.org/10.1124/mol.112.078709

  8. Matherly, Larry H.

    1. Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology October 2012, 82 (4) 591-600; DOI: https://doi.org/10.1124/mol.112.079004

  9. McCubrey, James A.

    1. Therapeutic Potential of Nitric Oxide-Modified Drugs in Colon Cancer Cells
      Marija Mojic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Djordje Miljkovic, Stanislava Stosic-Grujicic, Marija Stankovic, Katia Mangano, Salvatore Travali, Marco Donia, Paolo Fagone, Mai-Britt Zocca, Yousef Al-Abed, James A. McCubrey and Ferdinando Nicoletti
      Molecular Pharmacology October 2012, 82 (4) 700-710; DOI: https://doi.org/10.1124/mol.112.077842

  10. McGeehan, Gerard M.

    1. Regulation of Sphingomyelin Phosphodiesterase Acid-Like 3A Gene (SMPDL3A) by Liver X Receptors
      Paul B. Noto, Yuri Bukhtiyarov, Meng Shi, Brian M. McKeever, Gerard M. McGeehan and Deepak S. Lala
      Molecular Pharmacology October 2012, 82 (4) 719-727; DOI: https://doi.org/10.1124/mol.112.078865

  11. McKeever, Brian M.

    1. Regulation of Sphingomyelin Phosphodiesterase Acid-Like 3A Gene (SMPDL3A) by Liver X Receptors
      Paul B. Noto, Yuri Bukhtiyarov, Meng Shi, Brian M. McKeever, Gerard M. McGeehan and Deepak S. Lala
      Molecular Pharmacology October 2012, 82 (4) 719-727; DOI: https://doi.org/10.1124/mol.112.078865

  12. McNamara, James O.

    1. RNA Aptamer-Based Functional Ligands of the Neurotrophin Receptor, TrkB
      Yang Zhong Huang, Frank J. Hernandez, Bin Gu, Katie R. Stockdale, Kishore Nanapaneni, Todd E. Scheetz, Mark A. Behlke, Andrew S. Peek, Thomas Bair, Paloma H. Giangrande and James O. McNamara
      Molecular Pharmacology October 2012, 82 (4) 623-635; DOI: https://doi.org/10.1124/mol.112.078220

  13. Mijatovic, Sanja

    1. Therapeutic Potential of Nitric Oxide-Modified Drugs in Colon Cancer Cells
      Marija Mojic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Djordje Miljkovic, Stanislava Stosic-Grujicic, Marija Stankovic, Katia Mangano, Salvatore Travali, Marco Donia, Paolo Fagone, Mai-Britt Zocca, Yousef Al-Abed, James A. McCubrey and Ferdinando Nicoletti
      Molecular Pharmacology October 2012, 82 (4) 700-710; DOI: https://doi.org/10.1124/mol.112.077842

  14. Miljkovic, Djordje

    1. Therapeutic Potential of Nitric Oxide-Modified Drugs in Colon Cancer Cells
      Marija Mojic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Djordje Miljkovic, Stanislava Stosic-Grujicic, Marija Stankovic, Katia Mangano, Salvatore Travali, Marco Donia, Paolo Fagone, Mai-Britt Zocca, Yousef Al-Abed, James A. McCubrey and Ferdinando Nicoletti
      Molecular Pharmacology October 2012, 82 (4) 700-710; DOI: https://doi.org/10.1124/mol.112.077842

  15. Mojic, Marija

    1. Therapeutic Potential of Nitric Oxide-Modified Drugs in Colon Cancer Cells
      Marija Mojic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Djordje Miljkovic, Stanislava Stosic-Grujicic, Marija Stankovic, Katia Mangano, Salvatore Travali, Marco Donia, Paolo Fagone, Mai-Britt Zocca, Yousef Al-Abed, James A. McCubrey and Ferdinando Nicoletti
      Molecular Pharmacology October 2012, 82 (4) 700-710; DOI: https://doi.org/10.1124/mol.112.077842

N

  1. Nair, Bipin G.

    1. Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9
      Athira Omanakuttan, Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Nanjan Pandurangan, Rebu K. Varghese, Geetha B. Kumar, John A. Tainer, Asoke Banerji, J. Jefferson P. Perry and Bipin G. Nair
      Molecular Pharmacology October 2012, 82 (4) 614-622; DOI: https://doi.org/10.1124/mol.112.079020

  2. Nakajima, Ken-ichiro

    1. Design and Functional Characterization of a Novel, Arrestin-Biased Designer G Protein-Coupled Receptor
      Ken-ichiro Nakajima and Jürgen Wess
      Molecular Pharmacology October 2012, 82 (4) 575-582; DOI: https://doi.org/10.1124/mol.112.080358

  3. Nakano, Mariko

    1. CYP4V2 in Bietti's Crystalline Dystrophy: Ocular Localization, Metabolism of ω-3-Polyunsaturated Fatty Acids, and Functional Deficit of the p.H331P Variant
      Mariko Nakano, Edward J. Kelly, Constanze Wiek, Helmut Hanenberg and Allan E. Rettie
      Molecular Pharmacology October 2012, 82 (4) 679-686; DOI: https://doi.org/10.1124/mol.112.080085

  4. Nambiar, Jyotsna

    1. Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9
      Athira Omanakuttan, Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Nanjan Pandurangan, Rebu K. Varghese, Geetha B. Kumar, John A. Tainer, Asoke Banerji, J. Jefferson P. Perry and Bipin G. Nair
      Molecular Pharmacology October 2012, 82 (4) 614-622; DOI: https://doi.org/10.1124/mol.112.079020

  5. Nanapaneni, Kishore

    1. RNA Aptamer-Based Functional Ligands of the Neurotrophin Receptor, TrkB
      Yang Zhong Huang, Frank J. Hernandez, Bin Gu, Katie R. Stockdale, Kishore Nanapaneni, Todd E. Scheetz, Mark A. Behlke, Andrew S. Peek, Thomas Bair, Paloma H. Giangrande and James O. McNamara
      Molecular Pharmacology October 2012, 82 (4) 623-635; DOI: https://doi.org/10.1124/mol.112.078220

  6. Nemecz, Ákos

    1. Synthesis of Selective Agonists for the α7 Nicotinic Acetylcholine Receptor with In Situ Click-Chemistry on Acetylcholine-Binding Protein Templates
      John G. Yamauchi, Kimberly Gomez, Neil Grimster, Mikael Dufouil, Ákos Nemecz, Joseph R. Fotsing, Kwok-Yiu Ho, Todd T. Talley, K. Barry Sharpless, Valery V. Fokin and Palmer Taylor
      Molecular Pharmacology October 2012, 82 (4) 687-699; DOI: https://doi.org/10.1124/mol.112.080291

  7. Nicke, Annette

    1. Efficient Binding of 4/7 α-Conotoxins to Nicotinic α4β2 Receptors Is Prevented by Arg185 and Pro195 in the α4 Subunit
      Mirko Beissner, Sébastien Dutertre, Rudolf Schemm, Timm Danker, Annett Sporning, Helmut Grubmüller and Annette Nicke
      Molecular Pharmacology October 2012, 82 (4) 711-718; DOI: https://doi.org/10.1124/mol.112.078683

  8. Nicoletti, Ferdinando

    1. Therapeutic Potential of Nitric Oxide-Modified Drugs in Colon Cancer Cells
      Marija Mojic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Djordje Miljkovic, Stanislava Stosic-Grujicic, Marija Stankovic, Katia Mangano, Salvatore Travali, Marco Donia, Paolo Fagone, Mai-Britt Zocca, Yousef Al-Abed, James A. McCubrey and Ferdinando Nicoletti
      Molecular Pharmacology October 2012, 82 (4) 700-710; DOI: https://doi.org/10.1124/mol.112.077842

  9. North, R. Alan

    1. Activation of Trimeric P2X2 Receptors by Fewer than Three ATP Molecules
      Olga Stelmashenko, Ulyana Lalo, Yue Yang, Laricia Bragg, R. Alan North and Vincent Compan
      Molecular Pharmacology October 2012, 82 (4) 760-766; DOI: https://doi.org/10.1124/mol.112.080903

  10. Noto, Paul B.

    1. Regulation of Sphingomyelin Phosphodiesterase Acid-Like 3A Gene (SMPDL3A) by Liver X Receptors
      Paul B. Noto, Yuri Bukhtiyarov, Meng Shi, Brian M. McKeever, Gerard M. McGeehan and Deepak S. Lala
      Molecular Pharmacology October 2012, 82 (4) 719-727; DOI: https://doi.org/10.1124/mol.112.078865

O

  1. Omanakuttan, Athira

    1. Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9
      Athira Omanakuttan, Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Nanjan Pandurangan, Rebu K. Varghese, Geetha B. Kumar, John A. Tainer, Asoke Banerji, J. Jefferson P. Perry and Bipin G. Nair
      Molecular Pharmacology October 2012, 82 (4) 614-622; DOI: https://doi.org/10.1124/mol.112.079020

P

  1. Pandurangan, Nanjan

    1. Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9
      Athira Omanakuttan, Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Nanjan Pandurangan, Rebu K. Varghese, Geetha B. Kumar, John A. Tainer, Asoke Banerji, J. Jefferson P. Perry and Bipin G. Nair
      Molecular Pharmacology October 2012, 82 (4) 614-622; DOI: https://doi.org/10.1124/mol.112.079020

  2. Papke, Roger L.

    1. Intrinsically Low Open Probability of α7 Nicotinic Acetylcholine Receptors Can Be Overcome by Positive Allosteric Modulation and Serum Factors Leading to the Generation of Excitotoxic Currents at Physiological Temperatures
      Dustin K. Williams, Can Peng, Matthew R. Kimbrell and Roger L. Papke
      Molecular Pharmacology October 2012, 82 (4) 746-759; DOI: https://doi.org/10.1124/mol.112.080317

  3. Peek, Andrew S.

    1. RNA Aptamer-Based Functional Ligands of the Neurotrophin Receptor, TrkB
      Yang Zhong Huang, Frank J. Hernandez, Bin Gu, Katie R. Stockdale, Kishore Nanapaneni, Todd E. Scheetz, Mark A. Behlke, Andrew S. Peek, Thomas Bair, Paloma H. Giangrande and James O. McNamara
      Molecular Pharmacology October 2012, 82 (4) 623-635; DOI: https://doi.org/10.1124/mol.112.078220

  4. Peng, Can

    1. Intrinsically Low Open Probability of α7 Nicotinic Acetylcholine Receptors Can Be Overcome by Positive Allosteric Modulation and Serum Factors Leading to the Generation of Excitotoxic Currents at Physiological Temperatures
      Dustin K. Williams, Can Peng, Matthew R. Kimbrell and Roger L. Papke
      Molecular Pharmacology October 2012, 82 (4) 746-759; DOI: https://doi.org/10.1124/mol.112.080317

  5. Perry, J. Jefferson P.

    1. Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9
      Athira Omanakuttan, Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Nanjan Pandurangan, Rebu K. Varghese, Geetha B. Kumar, John A. Tainer, Asoke Banerji, J. Jefferson P. Perry and Bipin G. Nair
      Molecular Pharmacology October 2012, 82 (4) 614-622; DOI: https://doi.org/10.1124/mol.112.079020

  6. Polin, Lisa

    1. Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology October 2012, 82 (4) 591-600; DOI: https://doi.org/10.1124/mol.112.079004

  7. Prough, R. A.

    1. Activator Protein-1 Regulation of Murine Aldehyde Dehydrogenase 1a1
      N. L. Makia, I. Amunom, K. C. Falkner, D. J. Conklin, S. Surapureddi, J. A. Goldstein and R. A. Prough
      Molecular Pharmacology October 2012, 82 (4) 601-613; DOI: https://doi.org/10.1124/mol.112.078147

R

  1. Rettie, Allan E.

    1. CYP4V2 in Bietti's Crystalline Dystrophy: Ocular Localization, Metabolism of ω-3-Polyunsaturated Fatty Acids, and Functional Deficit of the p.H331P Variant
      Mariko Nakano, Edward J. Kelly, Constanze Wiek, Helmut Hanenberg and Allan E. Rettie
      Molecular Pharmacology October 2012, 82 (4) 679-686; DOI: https://doi.org/10.1124/mol.112.080085

  2. Rivera, Manuel

    1. Block of Human CaV3 Channels by the Diuretic Amiloride
      Osbaldo Lopez-Charcas, Manuel Rivera and Juan C. Gomora
      Molecular Pharmacology October 2012, 82 (4) 658-667; DOI: https://doi.org/10.1124/mol.112.078923

S

  1. Scheetz, Todd E.

    1. RNA Aptamer-Based Functional Ligands of the Neurotrophin Receptor, TrkB
      Yang Zhong Huang, Frank J. Hernandez, Bin Gu, Katie R. Stockdale, Kishore Nanapaneni, Todd E. Scheetz, Mark A. Behlke, Andrew S. Peek, Thomas Bair, Paloma H. Giangrande and James O. McNamara
      Molecular Pharmacology October 2012, 82 (4) 623-635; DOI: https://doi.org/10.1124/mol.112.078220

  2. Schemm, Rudolf

    1. Efficient Binding of 4/7 α-Conotoxins to Nicotinic α4β2 Receptors Is Prevented by Arg185 and Pro195 in the α4 Subunit
      Mirko Beissner, Sébastien Dutertre, Rudolf Schemm, Timm Danker, Annett Sporning, Helmut Grubmüller and Annette Nicke
      Molecular Pharmacology October 2012, 82 (4) 711-718; DOI: https://doi.org/10.1124/mol.112.078683

  3. Schinkel, Alfred H.

    1. P-Glycoprotein, Multidrug-Resistance Associated Protein 2, Cyp3a, and Carboxylesterase Affect the Oral Availability and Metabolism of Vinorelbine
      Jurjen S. Lagas, Carola W. N. Damen, Robert A. B. van Waterschoot, Dilek Iusuf, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology October 2012, 82 (4) 636-644; DOI: https://doi.org/10.1124/mol.111.077099

  4. Sharpless, K. Barry

    1. Synthesis of Selective Agonists for the α7 Nicotinic Acetylcholine Receptor with In Situ Click-Chemistry on Acetylcholine-Binding Protein Templates
      John G. Yamauchi, Kimberly Gomez, Neil Grimster, Mikael Dufouil, Ákos Nemecz, Joseph R. Fotsing, Kwok-Yiu Ho, Todd T. Talley, K. Barry Sharpless, Valery V. Fokin and Palmer Taylor
      Molecular Pharmacology October 2012, 82 (4) 687-699; DOI: https://doi.org/10.1124/mol.112.080291

  5. Shi, Meng

    1. Regulation of Sphingomyelin Phosphodiesterase Acid-Like 3A Gene (SMPDL3A) by Liver X Receptors
      Paul B. Noto, Yuri Bukhtiyarov, Meng Shi, Brian M. McKeever, Gerard M. McGeehan and Deepak S. Lala
      Molecular Pharmacology October 2012, 82 (4) 719-727; DOI: https://doi.org/10.1124/mol.112.078865

  6. Simons, Peter C.

    1. Discovery of Regulators of Receptor Internalization with High-Throughput Flow Cytometry
      Yang Wu, Phillip H. Tapia, Gregory W. Fisher, Peter C. Simons, J. Jacob Strouse, Terry Foutz, Alan S. Waggoner, Jonathan Jarvik and Larry A. Sklar
      Molecular Pharmacology October 2012, 82 (4) 645-657; DOI: https://doi.org/10.1124/mol.112.079897

  7. Sklar, Larry A.

    1. Discovery of Regulators of Receptor Internalization with High-Throughput Flow Cytometry
      Yang Wu, Phillip H. Tapia, Gregory W. Fisher, Peter C. Simons, J. Jacob Strouse, Terry Foutz, Alan S. Waggoner, Jonathan Jarvik and Larry A. Sklar
      Molecular Pharmacology October 2012, 82 (4) 645-657; DOI: https://doi.org/10.1124/mol.112.079897

  8. Sporning, Annett

    1. Efficient Binding of 4/7 α-Conotoxins to Nicotinic α4β2 Receptors Is Prevented by Arg185 and Pro195 in the α4 Subunit
      Mirko Beissner, Sébastien Dutertre, Rudolf Schemm, Timm Danker, Annett Sporning, Helmut Grubmüller and Annette Nicke
      Molecular Pharmacology October 2012, 82 (4) 711-718; DOI: https://doi.org/10.1124/mol.112.078683

  9. Stankovic, Marija

    1. Therapeutic Potential of Nitric Oxide-Modified Drugs in Colon Cancer Cells
      Marija Mojic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Djordje Miljkovic, Stanislava Stosic-Grujicic, Marija Stankovic, Katia Mangano, Salvatore Travali, Marco Donia, Paolo Fagone, Mai-Britt Zocca, Yousef Al-Abed, James A. McCubrey and Ferdinando Nicoletti
      Molecular Pharmacology October 2012, 82 (4) 700-710; DOI: https://doi.org/10.1124/mol.112.077842

  10. Stelmashenko, Olga

    1. Activation of Trimeric P2X2 Receptors by Fewer than Three ATP Molecules
      Olga Stelmashenko, Ulyana Lalo, Yue Yang, Laricia Bragg, R. Alan North and Vincent Compan
      Molecular Pharmacology October 2012, 82 (4) 760-766; DOI: https://doi.org/10.1124/mol.112.080903

  11. Stockdale, Katie R.

    1. RNA Aptamer-Based Functional Ligands of the Neurotrophin Receptor, TrkB
      Yang Zhong Huang, Frank J. Hernandez, Bin Gu, Katie R. Stockdale, Kishore Nanapaneni, Todd E. Scheetz, Mark A. Behlke, Andrew S. Peek, Thomas Bair, Paloma H. Giangrande and James O. McNamara
      Molecular Pharmacology October 2012, 82 (4) 623-635; DOI: https://doi.org/10.1124/mol.112.078220

  12. Stosic-Grujicic, Stanislava

    1. Therapeutic Potential of Nitric Oxide-Modified Drugs in Colon Cancer Cells
      Marija Mojic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Djordje Miljkovic, Stanislava Stosic-Grujicic, Marija Stankovic, Katia Mangano, Salvatore Travali, Marco Donia, Paolo Fagone, Mai-Britt Zocca, Yousef Al-Abed, James A. McCubrey and Ferdinando Nicoletti
      Molecular Pharmacology October 2012, 82 (4) 700-710; DOI: https://doi.org/10.1124/mol.112.077842

  13. Stout, Mark

    1. Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology October 2012, 82 (4) 591-600; DOI: https://doi.org/10.1124/mol.112.079004

  14. Strouse, J. Jacob

    1. Discovery of Regulators of Receptor Internalization with High-Throughput Flow Cytometry
      Yang Wu, Phillip H. Tapia, Gregory W. Fisher, Peter C. Simons, J. Jacob Strouse, Terry Foutz, Alan S. Waggoner, Jonathan Jarvik and Larry A. Sklar
      Molecular Pharmacology October 2012, 82 (4) 645-657; DOI: https://doi.org/10.1124/mol.112.079897

  15. Surapureddi, S.

    1. Activator Protein-1 Regulation of Murine Aldehyde Dehydrogenase 1a1
      N. L. Makia, I. Amunom, K. C. Falkner, D. J. Conklin, S. Surapureddi, J. A. Goldstein and R. A. Prough
      Molecular Pharmacology October 2012, 82 (4) 601-613; DOI: https://doi.org/10.1124/mol.112.078147

T

  1. Tainer, John A.

    1. Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9
      Athira Omanakuttan, Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Nanjan Pandurangan, Rebu K. Varghese, Geetha B. Kumar, John A. Tainer, Asoke Banerji, J. Jefferson P. Perry and Bipin G. Nair
      Molecular Pharmacology October 2012, 82 (4) 614-622; DOI: https://doi.org/10.1124/mol.112.079020

  2. Talley, Todd T.

    1. Synthesis of Selective Agonists for the α7 Nicotinic Acetylcholine Receptor with In Situ Click-Chemistry on Acetylcholine-Binding Protein Templates
      John G. Yamauchi, Kimberly Gomez, Neil Grimster, Mikael Dufouil, Ákos Nemecz, Joseph R. Fotsing, Kwok-Yiu Ho, Todd T. Talley, K. Barry Sharpless, Valery V. Fokin and Palmer Taylor
      Molecular Pharmacology October 2012, 82 (4) 687-699; DOI: https://doi.org/10.1124/mol.112.080291

  3. Tapia, Phillip H.

    1. Discovery of Regulators of Receptor Internalization with High-Throughput Flow Cytometry
      Yang Wu, Phillip H. Tapia, Gregory W. Fisher, Peter C. Simons, J. Jacob Strouse, Terry Foutz, Alan S. Waggoner, Jonathan Jarvik and Larry A. Sklar
      Molecular Pharmacology October 2012, 82 (4) 645-657; DOI: https://doi.org/10.1124/mol.112.079897

  4. Taylor, Palmer

    1. Synthesis of Selective Agonists for the α7 Nicotinic Acetylcholine Receptor with In Situ Click-Chemistry on Acetylcholine-Binding Protein Templates
      John G. Yamauchi, Kimberly Gomez, Neil Grimster, Mikael Dufouil, Ákos Nemecz, Joseph R. Fotsing, Kwok-Yiu Ho, Todd T. Talley, K. Barry Sharpless, Valery V. Fokin and Palmer Taylor
      Molecular Pharmacology October 2012, 82 (4) 687-699; DOI: https://doi.org/10.1124/mol.112.080291

  5. Travali, Salvatore

    1. Therapeutic Potential of Nitric Oxide-Modified Drugs in Colon Cancer Cells
      Marija Mojic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Djordje Miljkovic, Stanislava Stosic-Grujicic, Marija Stankovic, Katia Mangano, Salvatore Travali, Marco Donia, Paolo Fagone, Mai-Britt Zocca, Yousef Al-Abed, James A. McCubrey and Ferdinando Nicoletti
      Molecular Pharmacology October 2012, 82 (4) 700-710; DOI: https://doi.org/10.1124/mol.112.077842

  6. Trejo, JoAnn

    1. Ubiquitination of G Protein-Coupled Receptors: Functional Implications and Drug Discovery
      Michael R. Dores and JoAnn Trejo
      Molecular Pharmacology October 2012, 82 (4) 563-570; DOI: https://doi.org/10.1124/mol.112.079418

V

  1. van Waterschoot, Robert A. B.

    1. P-Glycoprotein, Multidrug-Resistance Associated Protein 2, Cyp3a, and Carboxylesterase Affect the Oral Availability and Metabolism of Vinorelbine
      Jurjen S. Lagas, Carola W. N. Damen, Robert A. B. van Waterschoot, Dilek Iusuf, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology October 2012, 82 (4) 636-644; DOI: https://doi.org/10.1124/mol.111.077099

  2. Varghese, Rebu K.

    1. Anacardic Acid Inhibits the Catalytic Activity of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9
      Athira Omanakuttan, Jyotsna Nambiar, Rodney M. Harris, Chinchu Bose, Nanjan Pandurangan, Rebu K. Varghese, Geetha B. Kumar, John A. Tainer, Asoke Banerji, J. Jefferson P. Perry and Bipin G. Nair
      Molecular Pharmacology October 2012, 82 (4) 614-622; DOI: https://doi.org/10.1124/mol.112.079020

W

  1. Waggoner, Alan S.

    1. Discovery of Regulators of Receptor Internalization with High-Throughput Flow Cytometry
      Yang Wu, Phillip H. Tapia, Gregory W. Fisher, Peter C. Simons, J. Jacob Strouse, Terry Foutz, Alan S. Waggoner, Jonathan Jarvik and Larry A. Sklar
      Molecular Pharmacology October 2012, 82 (4) 645-657; DOI: https://doi.org/10.1124/mol.112.079897

  2. Wagner, Jill M.

    1. Identification of DNA Repair Pathways That Affect the Survival of Ovarian Cancer Cells Treated with a Poly(ADP-Ribose) Polymerase Inhibitor in a Novel Drug Combination
      Amelia M. Huehls, Jill M. Wagner, Catherine J. Huntoon and Larry M. Karnitz
      Molecular Pharmacology October 2012, 82 (4) 767-776; DOI: https://doi.org/10.1124/mol.112.080614

  3. Wang, Lei

    1. Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology October 2012, 82 (4) 591-600; DOI: https://doi.org/10.1124/mol.112.079004

  4. Wang, Shuai

    1. Increasing Human Th17 Differentiation through Activation of Orphan Nuclear Receptor Retinoid Acid-Related Orphan Receptor γ (RORγ) by a Class of Aryl Amide Compounds
      Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
      Molecular Pharmacology October 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667

  5. Wang, Yonghui

    1. Increasing Human Th17 Differentiation through Activation of Orphan Nuclear Receptor Retinoid Acid-Related Orphan Receptor γ (RORγ) by a Class of Aryl Amide Compounds
      Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
      Molecular Pharmacology October 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667

  6. Wess, Jürgen

    1. Design and Functional Characterization of a Novel, Arrestin-Biased Designer G Protein-Coupled Receptor
      Ken-ichiro Nakajima and Jürgen Wess
      Molecular Pharmacology October 2012, 82 (4) 575-582; DOI: https://doi.org/10.1124/mol.112.080358

  7. White, Kathryn

    1. Functional Loss of the Reduced Folate Carrier Enhances the Antitumor Activities of Novel Antifolates with Selective Uptake by the Proton-Coupled Folate Transporter
      Sita Kugel Desmoulin, Lei Wang, Lisa Polin, Kathryn White, Juiwanna Kushner, Mark Stout, Zhanjun Hou, Christina Cherian, Aleem Gangjee and Larry H. Matherly
      Molecular Pharmacology October 2012, 82 (4) 591-600; DOI: https://doi.org/10.1124/mol.112.079004

  8. Wiek, Constanze

    1. CYP4V2 in Bietti's Crystalline Dystrophy: Ocular Localization, Metabolism of ω-3-Polyunsaturated Fatty Acids, and Functional Deficit of the p.H331P Variant
      Mariko Nakano, Edward J. Kelly, Constanze Wiek, Helmut Hanenberg and Allan E. Rettie
      Molecular Pharmacology October 2012, 82 (4) 679-686; DOI: https://doi.org/10.1124/mol.112.080085

  9. Williams, Dustin K.

    1. Intrinsically Low Open Probability of α7 Nicotinic Acetylcholine Receptors Can Be Overcome by Positive Allosteric Modulation and Serum Factors Leading to the Generation of Excitotoxic Currents at Physiological Temperatures
      Dustin K. Williams, Can Peng, Matthew R. Kimbrell and Roger L. Papke
      Molecular Pharmacology October 2012, 82 (4) 746-759; DOI: https://doi.org/10.1124/mol.112.080317

  10. Wisely, Bruce

    1. Increasing Human Th17 Differentiation through Activation of Orphan Nuclear Receptor Retinoid Acid-Related Orphan Receptor γ (RORγ) by a Class of Aryl Amide Compounds
      Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
      Molecular Pharmacology October 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667

  11. Wu, Yang

    1. Discovery of Regulators of Receptor Internalization with High-Throughput Flow Cytometry
      Yang Wu, Phillip H. Tapia, Gregory W. Fisher, Peter C. Simons, J. Jacob Strouse, Terry Foutz, Alan S. Waggoner, Jonathan Jarvik and Larry A. Sklar
      Molecular Pharmacology October 2012, 82 (4) 645-657; DOI: https://doi.org/10.1124/mol.112.079897

X

  1. Xiang, Zhijun

    1. Increasing Human Th17 Differentiation through Activation of Orphan Nuclear Receptor Retinoid Acid-Related Orphan Receptor γ (RORγ) by a Class of Aryl Amide Compounds
      Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
      Molecular Pharmacology October 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667

  2. Xin, Xiaonan

    1. A Role for Kalirin in the Response of Rat Medium Spiny Neurons to Cocaine
      Xin-Ming Ma, Jian-ping Huang, Xiaonan Xin, Yan Yan, Richard E. Mains and Betty A. Eipper
      Molecular Pharmacology October 2012, 82 (4) 738-745; DOI: https://doi.org/10.1124/mol.112.080044

Y

  1. Yamauchi, John G.

    1. Synthesis of Selective Agonists for the α7 Nicotinic Acetylcholine Receptor with In Situ Click-Chemistry on Acetylcholine-Binding Protein Templates
      John G. Yamauchi, Kimberly Gomez, Neil Grimster, Mikael Dufouil, Ákos Nemecz, Joseph R. Fotsing, Kwok-Yiu Ho, Todd T. Talley, K. Barry Sharpless, Valery V. Fokin and Palmer Taylor
      Molecular Pharmacology October 2012, 82 (4) 687-699; DOI: https://doi.org/10.1124/mol.112.080291

  2. Yan, Yan

    1. A Role for Kalirin in the Response of Rat Medium Spiny Neurons to Cocaine
      Xin-Ming Ma, Jian-ping Huang, Xiaonan Xin, Yan Yan, Richard E. Mains and Betty A. Eipper
      Molecular Pharmacology October 2012, 82 (4) 738-745; DOI: https://doi.org/10.1124/mol.112.080044

  3. Yang, Yue

    1. Activation of Trimeric P2X2 Receptors by Fewer than Three ATP Molecules
      Olga Stelmashenko, Ulyana Lalo, Yue Yang, Laricia Bragg, R. Alan North and Vincent Compan
      Molecular Pharmacology October 2012, 82 (4) 760-766; DOI: https://doi.org/10.1124/mol.112.080903

Z

  1. Zhang, Guifeng

    1. Increasing Human Th17 Differentiation through Activation of Orphan Nuclear Receptor Retinoid Acid-Related Orphan Receptor γ (RORγ) by a Class of Aryl Amide Compounds
      Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
      Molecular Pharmacology October 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667

  2. Zhang, Jing

    1. Increasing Human Th17 Differentiation through Activation of Orphan Nuclear Receptor Retinoid Acid-Related Orphan Receptor γ (RORγ) by a Class of Aryl Amide Compounds
      Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
      Molecular Pharmacology October 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667

  3. Zhang, Wei

    1. Increasing Human Th17 Differentiation through Activation of Orphan Nuclear Receptor Retinoid Acid-Related Orphan Receptor γ (RORγ) by a Class of Aryl Amide Compounds
      Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
      Molecular Pharmacology October 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667

  4. Zhong, Zhong

    1. Increasing Human Th17 Differentiation through Activation of Orphan Nuclear Receptor Retinoid Acid-Related Orphan Receptor γ (RORγ) by a Class of Aryl Amide Compounds
      Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
      Molecular Pharmacology October 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667

  5. Zhou, Ling

    1. Increasing Human Th17 Differentiation through Activation of Orphan Nuclear Receptor Retinoid Acid-Related Orphan Receptor γ (RORγ) by a Class of Aryl Amide Compounds
      Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
      Molecular Pharmacology October 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667

  6. Zocca, Mai-Britt

    1. Therapeutic Potential of Nitric Oxide-Modified Drugs in Colon Cancer Cells
      Marija Mojic, Sanja Mijatovic, Danijela Maksimovic-Ivanic, Djordje Miljkovic, Stanislava Stosic-Grujicic, Marija Stankovic, Katia Mangano, Salvatore Travali, Marco Donia, Paolo Fagone, Mai-Britt Zocca, Yousef Al-Abed, James A. McCubrey and Ferdinando Nicoletti
      Molecular Pharmacology October 2012, 82 (4) 700-710; DOI: https://doi.org/10.1124/mol.112.077842
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