Research ArticleArticle
Increasing Human Th17 Differentiation through Activation of Orphan Nuclear Receptor Retinoid Acid-Related Orphan Receptor γ (RORγ) by a Class of Aryl Amide Compounds
Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
Molecular Pharmacology October 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667
Wei Zhang
Discovery Technology (W.Z., J.Z., L.F., S.W., Y.L., G.Z., G.A., Z.Z.), Medicinal Chemistry (Y.W.), and Neuroinflammation Discovery Performance Unit (W.Z., J.Z., L.F., L.Z., Z.X., Y.W., S.L.), GlaxoSmithKline R&D Center, Shanghai, China; and Biological Reagents and Assay Development, Platform Technology Science, GlaxoSmithKline, Research Triangle Park, North Carolina (B.W.)
Jing Zhang
Discovery Technology (W.Z., J.Z., L.F., S.W., Y.L., G.Z., G.A., Z.Z.), Medicinal Chemistry (Y.W.), and Neuroinflammation Discovery Performance Unit (W.Z., J.Z., L.F., L.Z., Z.X., Y.W., S.L.), GlaxoSmithKline R&D Center, Shanghai, China; and Biological Reagents and Assay Development, Platform Technology Science, GlaxoSmithKline, Research Triangle Park, North Carolina (B.W.)
Leiping Fang
Discovery Technology (W.Z., J.Z., L.F., S.W., Y.L., G.Z., G.A., Z.Z.), Medicinal Chemistry (Y.W.), and Neuroinflammation Discovery Performance Unit (W.Z., J.Z., L.F., L.Z., Z.X., Y.W., S.L.), GlaxoSmithKline R&D Center, Shanghai, China; and Biological Reagents and Assay Development, Platform Technology Science, GlaxoSmithKline, Research Triangle Park, North Carolina (B.W.)
Ling Zhou
Discovery Technology (W.Z., J.Z., L.F., S.W., Y.L., G.Z., G.A., Z.Z.), Medicinal Chemistry (Y.W.), and Neuroinflammation Discovery Performance Unit (W.Z., J.Z., L.F., L.Z., Z.X., Y.W., S.L.), GlaxoSmithKline R&D Center, Shanghai, China; and Biological Reagents and Assay Development, Platform Technology Science, GlaxoSmithKline, Research Triangle Park, North Carolina (B.W.)
Shuai Wang
Discovery Technology (W.Z., J.Z., L.F., S.W., Y.L., G.Z., G.A., Z.Z.), Medicinal Chemistry (Y.W.), and Neuroinflammation Discovery Performance Unit (W.Z., J.Z., L.F., L.Z., Z.X., Y.W., S.L.), GlaxoSmithKline R&D Center, Shanghai, China; and Biological Reagents and Assay Development, Platform Technology Science, GlaxoSmithKline, Research Triangle Park, North Carolina (B.W.)
Zhijun Xiang
Discovery Technology (W.Z., J.Z., L.F., S.W., Y.L., G.Z., G.A., Z.Z.), Medicinal Chemistry (Y.W.), and Neuroinflammation Discovery Performance Unit (W.Z., J.Z., L.F., L.Z., Z.X., Y.W., S.L.), GlaxoSmithKline R&D Center, Shanghai, China; and Biological Reagents and Assay Development, Platform Technology Science, GlaxoSmithKline, Research Triangle Park, North Carolina (B.W.)
Yuan Li
Discovery Technology (W.Z., J.Z., L.F., S.W., Y.L., G.Z., G.A., Z.Z.), Medicinal Chemistry (Y.W.), and Neuroinflammation Discovery Performance Unit (W.Z., J.Z., L.F., L.Z., Z.X., Y.W., S.L.), GlaxoSmithKline R&D Center, Shanghai, China; and Biological Reagents and Assay Development, Platform Technology Science, GlaxoSmithKline, Research Triangle Park, North Carolina (B.W.)
Bruce Wisely
Discovery Technology (W.Z., J.Z., L.F., S.W., Y.L., G.Z., G.A., Z.Z.), Medicinal Chemistry (Y.W.), and Neuroinflammation Discovery Performance Unit (W.Z., J.Z., L.F., L.Z., Z.X., Y.W., S.L.), GlaxoSmithKline R&D Center, Shanghai, China; and Biological Reagents and Assay Development, Platform Technology Science, GlaxoSmithKline, Research Triangle Park, North Carolina (B.W.)
Guifeng Zhang
Discovery Technology (W.Z., J.Z., L.F., S.W., Y.L., G.Z., G.A., Z.Z.), Medicinal Chemistry (Y.W.), and Neuroinflammation Discovery Performance Unit (W.Z., J.Z., L.F., L.Z., Z.X., Y.W., S.L.), GlaxoSmithKline R&D Center, Shanghai, China; and Biological Reagents and Assay Development, Platform Technology Science, GlaxoSmithKline, Research Triangle Park, North Carolina (B.W.)
Gang An
Discovery Technology (W.Z., J.Z., L.F., S.W., Y.L., G.Z., G.A., Z.Z.), Medicinal Chemistry (Y.W.), and Neuroinflammation Discovery Performance Unit (W.Z., J.Z., L.F., L.Z., Z.X., Y.W., S.L.), GlaxoSmithKline R&D Center, Shanghai, China; and Biological Reagents and Assay Development, Platform Technology Science, GlaxoSmithKline, Research Triangle Park, North Carolina (B.W.)
Yonghui Wang
Discovery Technology (W.Z., J.Z., L.F., S.W., Y.L., G.Z., G.A., Z.Z.), Medicinal Chemistry (Y.W.), and Neuroinflammation Discovery Performance Unit (W.Z., J.Z., L.F., L.Z., Z.X., Y.W., S.L.), GlaxoSmithKline R&D Center, Shanghai, China; and Biological Reagents and Assay Development, Platform Technology Science, GlaxoSmithKline, Research Triangle Park, North Carolina (B.W.)
Stewart Leung
Discovery Technology (W.Z., J.Z., L.F., S.W., Y.L., G.Z., G.A., Z.Z.), Medicinal Chemistry (Y.W.), and Neuroinflammation Discovery Performance Unit (W.Z., J.Z., L.F., L.Z., Z.X., Y.W., S.L.), GlaxoSmithKline R&D Center, Shanghai, China; and Biological Reagents and Assay Development, Platform Technology Science, GlaxoSmithKline, Research Triangle Park, North Carolina (B.W.)
Zhong Zhong
Discovery Technology (W.Z., J.Z., L.F., S.W., Y.L., G.Z., G.A., Z.Z.), Medicinal Chemistry (Y.W.), and Neuroinflammation Discovery Performance Unit (W.Z., J.Z., L.F., L.Z., Z.X., Y.W., S.L.), GlaxoSmithKline R&D Center, Shanghai, China; and Biological Reagents and Assay Development, Platform Technology Science, GlaxoSmithKline, Research Triangle Park, North Carolina (B.W.)

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Research ArticleArticle
RORγ Activation by Potent Small-Molecule Compounds
Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
Molecular Pharmacology October 1, 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667
Research ArticleArticle
RORγ Activation by Potent Small-Molecule Compounds
Wei Zhang, Jing Zhang, Leiping Fang, Ling Zhou, Shuai Wang, Zhijun Xiang, Yuan Li, Bruce Wisely, Guifeng Zhang, Gang An, Yonghui Wang, Stewart Leung and Zhong Zhong
Molecular Pharmacology October 1, 2012, 82 (4) 583-590; DOI: https://doi.org/10.1124/mol.112.078667
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