Research ArticleArticle
P-Glycoprotein, Multidrug-Resistance Associated Protein 2, Cyp3a, and Carboxylesterase Affect the Oral Availability and Metabolism of Vinorelbine
Jurjen S. Lagas, Carola W. N. Damen, Robert A. B. van Waterschoot, Dilek Iusuf, Jos H. Beijnen and Alfred H. Schinkel
Molecular Pharmacology October 2012, 82 (4) 636-644; DOI: https://doi.org/10.1124/mol.111.077099
Jurjen S. Lagas
Division of Molecular Oncology (J.S.L., R.A.B.v.W., D.I., A.H.S.), The Netherlands Cancer Institute, Amsterdam, The Netherlands; and Department of Pharmacy and Pharmacology, Slotervaart Hospital, Amsterdam, the Netherlands (J.S.L., C.W.N.D., J.H.B.)
Carola W. N. Damen
Division of Molecular Oncology (J.S.L., R.A.B.v.W., D.I., A.H.S.), The Netherlands Cancer Institute, Amsterdam, The Netherlands; and Department of Pharmacy and Pharmacology, Slotervaart Hospital, Amsterdam, the Netherlands (J.S.L., C.W.N.D., J.H.B.)
Robert A. B. van Waterschoot
Division of Molecular Oncology (J.S.L., R.A.B.v.W., D.I., A.H.S.), The Netherlands Cancer Institute, Amsterdam, The Netherlands; and Department of Pharmacy and Pharmacology, Slotervaart Hospital, Amsterdam, the Netherlands (J.S.L., C.W.N.D., J.H.B.)
Dilek Iusuf
Division of Molecular Oncology (J.S.L., R.A.B.v.W., D.I., A.H.S.), The Netherlands Cancer Institute, Amsterdam, The Netherlands; and Department of Pharmacy and Pharmacology, Slotervaart Hospital, Amsterdam, the Netherlands (J.S.L., C.W.N.D., J.H.B.)
Jos H. Beijnen
Division of Molecular Oncology (J.S.L., R.A.B.v.W., D.I., A.H.S.), The Netherlands Cancer Institute, Amsterdam, The Netherlands; and Department of Pharmacy and Pharmacology, Slotervaart Hospital, Amsterdam, the Netherlands (J.S.L., C.W.N.D., J.H.B.)
Alfred H. Schinkel
Division of Molecular Oncology (J.S.L., R.A.B.v.W., D.I., A.H.S.), The Netherlands Cancer Institute, Amsterdam, The Netherlands; and Department of Pharmacy and Pharmacology, Slotervaart Hospital, Amsterdam, the Netherlands (J.S.L., C.W.N.D., J.H.B.)
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Research ArticleArticle
P-gp, Mrp2, Cyp3a, and Ces2a Affect Vinorelbine Availability
Jurjen S. Lagas, Carola W. N. Damen, Robert A. B. van Waterschoot, Dilek Iusuf, Jos H. Beijnen and Alfred H. Schinkel
Molecular Pharmacology October 1, 2012, 82 (4) 636-644; DOI: https://doi.org/10.1124/mol.111.077099
Research ArticleArticle
P-gp, Mrp2, Cyp3a, and Ces2a Affect Vinorelbine Availability
Jurjen S. Lagas, Carola W. N. Damen, Robert A. B. van Waterschoot, Dilek Iusuf, Jos H. Beijnen and Alfred H. Schinkel
Molecular Pharmacology October 1, 2012, 82 (4) 636-644; DOI: https://doi.org/10.1124/mol.111.077099
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