Research ArticleArticle
Efficient Binding of 4/7 α-Conotoxins to Nicotinic α4β2 Receptors Is Prevented by Arg185 and Pro195 in the α4 Subunit
Mirko Beissner, Sébastien Dutertre, Rudolf Schemm, Timm Danker, Annett Sporning, Helmut Grubmüller and Annette Nicke
Molecular Pharmacology October 2012, 82 (4) 711-718; DOI: https://doi.org/10.1124/mol.112.078683
Mirko Beissner
Department of Neurochemistry, Max Planck Institute for Brain Research, Frankfurt, Germany (M.B., A.N.); Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia (S.D.); Department of Theoretical and Computational Biophysics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany (R.S., H.G.); NMI Technologie Transfer GmbH, Reutlingen, Germany (T.D.); and Department of Molecular Biology of Neuronal Signals, Max Planck Institute for Experimental Medicine, Göttingen, Germany (A.S., A.N.)
Sébastien Dutertre
Department of Neurochemistry, Max Planck Institute for Brain Research, Frankfurt, Germany (M.B., A.N.); Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia (S.D.); Department of Theoretical and Computational Biophysics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany (R.S., H.G.); NMI Technologie Transfer GmbH, Reutlingen, Germany (T.D.); and Department of Molecular Biology of Neuronal Signals, Max Planck Institute for Experimental Medicine, Göttingen, Germany (A.S., A.N.)
Rudolf Schemm
Department of Neurochemistry, Max Planck Institute for Brain Research, Frankfurt, Germany (M.B., A.N.); Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia (S.D.); Department of Theoretical and Computational Biophysics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany (R.S., H.G.); NMI Technologie Transfer GmbH, Reutlingen, Germany (T.D.); and Department of Molecular Biology of Neuronal Signals, Max Planck Institute for Experimental Medicine, Göttingen, Germany (A.S., A.N.)
Timm Danker
Department of Neurochemistry, Max Planck Institute for Brain Research, Frankfurt, Germany (M.B., A.N.); Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia (S.D.); Department of Theoretical and Computational Biophysics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany (R.S., H.G.); NMI Technologie Transfer GmbH, Reutlingen, Germany (T.D.); and Department of Molecular Biology of Neuronal Signals, Max Planck Institute for Experimental Medicine, Göttingen, Germany (A.S., A.N.)
Annett Sporning
Department of Neurochemistry, Max Planck Institute for Brain Research, Frankfurt, Germany (M.B., A.N.); Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia (S.D.); Department of Theoretical and Computational Biophysics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany (R.S., H.G.); NMI Technologie Transfer GmbH, Reutlingen, Germany (T.D.); and Department of Molecular Biology of Neuronal Signals, Max Planck Institute for Experimental Medicine, Göttingen, Germany (A.S., A.N.)
Helmut Grubmüller
Department of Neurochemistry, Max Planck Institute for Brain Research, Frankfurt, Germany (M.B., A.N.); Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia (S.D.); Department of Theoretical and Computational Biophysics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany (R.S., H.G.); NMI Technologie Transfer GmbH, Reutlingen, Germany (T.D.); and Department of Molecular Biology of Neuronal Signals, Max Planck Institute for Experimental Medicine, Göttingen, Germany (A.S., A.N.)
Annette Nicke
Department of Neurochemistry, Max Planck Institute for Brain Research, Frankfurt, Germany (M.B., A.N.); Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia (S.D.); Department of Theoretical and Computational Biophysics, Max Planck Institute for Biophysical Chemistry, Göttingen, Germany (R.S., H.G.); NMI Technologie Transfer GmbH, Reutlingen, Germany (T.D.); and Department of Molecular Biology of Neuronal Signals, Max Planck Institute for Experimental Medicine, Göttingen, Germany (A.S., A.N.)

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Research ArticleArticle
α-Conotoxin Binding to α4β2 Receptors
Mirko Beissner, Sébastien Dutertre, Rudolf Schemm, Timm Danker, Annett Sporning, Helmut Grubmüller and Annette Nicke
Molecular Pharmacology October 1, 2012, 82 (4) 711-718; DOI: https://doi.org/10.1124/mol.112.078683
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