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Molecular Pharmacology

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Table of Contents

December 01, 2012; Volume 82,Issue 6

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    Drug Efflux Transporters and Multidrug Resistance in Acute Leukemia: Therapeutic Impact and Novel Approaches to Mediation
    Cindy Q. Xia and Peter G. Smith
    Molecular Pharmacology December 2012, 82 (6) 1008-1021; DOI: https://doi.org/10.1124/mol.112.079129

Articles

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    Generation and Characterization of Novel Cytochrome P450 Cyp2c Gene Cluster Knockout and CYP2C9 Humanized Mouse Lines
    Nico Scheer, Yury Kapelyukh, Lynsey Chatham, Anja Rode, Sandra Buechel and C. Roland Wolf
    Molecular Pharmacology December 2012, 82 (6) 1022-1029; DOI: https://doi.org/10.1124/mol.112.080036
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    Resveratrol Sensitizes Acute Myelogenous Leukemia Cells to Histone Deacetylase Inhibitors through Reactive Oxygen Species-Mediated Activation of the Extrinsic Apoptotic Pathway
    Alae Yaseen, Shuang Chen, Stefanie Hock, Roberto Rosato, Paul Dent, Yun Dai and Steven Grant
    Molecular Pharmacology December 2012, 82 (6) 1030-1041; DOI: https://doi.org/10.1124/mol.112.079624
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    Locating a Plausible Binding Site for an Open-Channel Blocker, GlyH-101, in the Pore of the Cystic Fibrosis Transmembrane Conductance Regulator
    Yohei Norimatsu, Anthony Ivetac, Christopher Alexander, Nicolette O'Donnell, Leah Frye, Mark S. P. Sansom and David C. Dawson
    Molecular Pharmacology December 2012, 82 (6) 1042-1055; DOI: https://doi.org/10.1124/mol.112.080267
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    Chronic Caffeine Intake in Adult Rat Inhibits Carotid Body Sensitization Produced by Chronic Sustained Hypoxia but Maintains Intact Chemoreflex Output
    Silvia V. Conde, Maria J. Ribeiro, Ana Obeso, Ricardo Rigual, Emilia C. Monteiro and Constancio Gonzalez
    Molecular Pharmacology December 2012, 82 (6) 1056-1065; DOI: https://doi.org/10.1124/mol.112.081216
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    Small Molecule Allosteric Modulation of the Glucagon-Like Peptide-1 Receptor Enhances the Insulinotropic Effect of Oxyntomodulin
    Francis S. Willard, Denise Wootten, Aaron D. Showalter, Emilia E. Savage, James Ficorilli, Thomas B. Farb, Krister Bokvist, Jorge Alsina-Fernandez, Sebastian G. B. Furness, Arthur Christopoulos, Patrick M. Sexton and Kyle W. Sloop
    Molecular Pharmacology December 2012, 82 (6) 1066-1073; DOI: https://doi.org/10.1124/mol.112.080432
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    Ifenprodil Effects on GluN2B-Containing Glutamate Receptors
    Stacy A. Amico-Ruvio, Meaghan A. Paganelli, Jason M. Myers and Gabriela K. Popescu
    Molecular Pharmacology December 2012, 82 (6) 1074-1081; DOI: https://doi.org/10.1124/mol.112.078998
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    Xenobiotics and Loss of Cell Adhesion Drive Distinct Transcriptional Outcomes by Aryl Hydrocarbon Receptor Signaling
    Nan Hao, Kian Leong Lee, Sebastian G. B. Furness, Cecilia Bosdotter, Lorenz Poellinger and Murray L. Whitelaw
    Molecular Pharmacology December 2012, 82 (6) 1082-1093; DOI: https://doi.org/10.1124/mol.112.078873
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    Identification of Structural Motifs Critical for Epstein-Barr Virus-Induced Molecule 2 Function and Homology Modeling of the Ligand Docking Site
    Li Zhang, Amy Y. Shih, Xia V. Yang, Chester Kuei, Jiejun Wu, Xiaohu Deng, Neelakandha S. Mani, Taraneh Mirzadegan, Siquan Sun, Timothy W. Lovenberg and Changlu Liu
    Molecular Pharmacology December 2012, 82 (6) 1094-1103; DOI: https://doi.org/10.1124/mol.112.080275
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    Solute Restriction Reveals an Essential Role for clag3-Associated Channels in Malaria Parasite Nutrient Acquisition
    Ajay D. Pillai, Wang Nguitragool, Brian Lyko, Keithlee Dolinta, Michelle M. Butler, Son T. Nguyen, Norton P. Peet, Terry L. Bowlin and Sanjay A. Desai
    Molecular Pharmacology December 2012, 82 (6) 1104-1114; DOI: https://doi.org/10.1124/mol.112.081224
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    Betulinic Acid Decreases Specificity Protein 1 (Sp1) Level via Increasing the Sumoylation of Sp1 to Inhibit Lung Cancer Growth
    Tsung-I. Hsu, Mei-Chun Wang, Szu-Yu Chen, Shih-Ting Huang, Yu-Min Yeh, Wu-Chou Su, Wen-Chang Chang and Jan-Jong Hung
    Molecular Pharmacology December 2012, 82 (6) 1115-1128; DOI: https://doi.org/10.1124/mol.112.078485
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    Extracellular Quaternary Ammonium Blockade of Transient Receptor Potential Vanilloid Subtype 1 Channels Expressed in Xenopus laevis Oocytes
    Ricardo E. Rivera-Acevedo, Stephan A. Pless, Stephan K. W. Schwarz and Christopher A. Ahern
    Molecular Pharmacology December 2012, 82 (6) 1129-1135; DOI: https://doi.org/10.1124/mol.112.079277
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    Gβγ Inhibits Exocytosis via Interaction with Critical Residues on Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein-25
    Christopher A. Wells, Zack Zurawski, Katherine M. Betke, Yun Young Yim, Karren Hyde, Shelagh Rodriguez, Simon Alford and Heidi E. Hamm
    Molecular Pharmacology December 2012, 82 (6) 1136-1149; DOI: https://doi.org/10.1124/mol.112.080507
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    Identification and Characterization of Distinct C-Terminal Domains of the Human Hydroxycarboxylic Acid Receptor-2 That Are Essential for Receptor Export, Constitutive Activity, Desensitization, and Internalization
    Guo Li, Qi Zhou, Yena Yu, Linjie Chen, Ying Shi, Jiansong Luo, Jeffrey Benovic, Jianxin Lu and Naiming Zhou
    Molecular Pharmacology December 2012, 82 (6) 1150-1161; DOI: https://doi.org/10.1124/mol.112.081307
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    Virtual Screening for LPA2-Specific Agonists Identifies a Nonlipid Compound with Antiapoptotic Actions
    Gyöngyi N. Kiss, James I. Fells, Renuka Gupte, Sue-Chin Lee, Jianxiong Liu, Nóra Nusser, Keng G. Lim, Ramesh M. Ray, Fang-Tsyr Lin, Abby L. Parrill, Balázs Sümegi, Duane D. Miller and Gabor Tigyi
    Molecular Pharmacology December 2012, 82 (6) 1162-1173; DOI: https://doi.org/10.1124/mol.112.079699
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    Analysis of Multiple Histamine H4 Receptor Compound Classes Uncovers Gαi Protein- and β-Arrestin2-Biased Ligands
    Saskia Nijmeijer, Henry F. Vischer, Elizabeth M. Rosethorne, Steven J. Charlton and Rob Leurs
    Molecular Pharmacology December 2012, 82 (6) 1174-1182; DOI: https://doi.org/10.1124/mol.112.080911
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    Cd2+ Block and Permeation of CaV3.1 (α1G) T-Type Calcium Channels: Candidate Mechanism for Cd2+ Influx
    Kyle V. Lopin, Frank Thévenod, Jessica C. Page and Stephen W. Jones
    Molecular Pharmacology December 2012, 82 (6) 1183-1193; DOI: https://doi.org/10.1124/mol.112.080176
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    Fe2+ Block and Permeation of CaV3.1 (α1G) T-Type Calcium Channels: Candidate Mechanism for Non–Transferrin-Mediated Fe2+ Influx
    Kyle V. Lopin, I. Patrick Gray, Carlos A. Obejero-Paz, Frank Thévenod and Stephen W. Jones
    Molecular Pharmacology December 2012, 82 (6) 1194-1204; DOI: https://doi.org/10.1124/mol.112.080184
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    Gene Expression Signature Predicting High-Grade Prostate Cancer Responses to Oxaliplatin
    Stéphane Puyo, Nadine Houédé, Audrey Kauffmann, Pierre Richaud, Jacques Robert and Philippe Pourquier
    Molecular Pharmacology December 2012, 82 (6) 1205-1216; DOI: https://doi.org/10.1124/mol.112.080333
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    Lapatinib and Obatoclax Kill Breast Cancer Cells through Reactive Oxygen Species-Dependent Endoplasmic Reticulum Stress
    Nichola Cruickshanks, Yong Tang, Laurence Booth, Hossein Hamed, Steven Grant and Paul Dent
    Molecular Pharmacology December 2012, 82 (6) 1217-1229; DOI: https://doi.org/10.1124/mol.112.081539
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    Inhibition of Autophagy as a Strategy to Augment Radiosensitization by the Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235
    George J. Cerniglia, Jayashree Karar, Sonia Tyagi, Melpo Christofidou-Solomidou, Ramesh Rengan, Constantinos Koumenis and Amit Maity
    Molecular Pharmacology December 2012, 82 (6) 1230-1240; DOI: https://doi.org/10.1124/mol.112.080408
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    Analysis of Kalirin-7 Knockout Mice Reveals Different Effects in Female Mice
    Christopher M. Mazzone, Taylor P. Larese, Drew D. Kiraly, Betty A. Eipper and Richard E. Mains
    Molecular Pharmacology December 2012, 82 (6) 1241-1249; DOI: https://doi.org/10.1124/mol.112.080838
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Molecular Pharmacology: 82 (6)
Molecular Pharmacology
Vol. 82, Issue 6
1 Dec 2012
  • Table of Contents
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