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Research ArticleArticle

Generation and Characterization of Novel Cytochrome P450 Cyp2c Gene Cluster Knockout and CYP2C9 Humanized Mouse Lines

Nico Scheer, Yury Kapelyukh, Lynsey Chatham, Anja Rode, Sandra Buechel and C. Roland Wolf
Molecular Pharmacology December 2012, 82 (6) 1022-1029; DOI: https://doi.org/10.1124/mol.112.080036

Article Information

vol. 82 no. 6 1022-1029
DOI 
https://doi.org/10.1124/mol.112.080036
PubMed 
22918969
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received May 25, 2012
  • Accepted August 23, 2012
  • Published online November 14, 2012.

Article Versions

Copyright & Usage 
Copyright © 2012 The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Nico Scheer,
  2. Yury Kapelyukh,
  3. Lynsey Chatham,
  4. Anja Rode,
  5. Sandra Buechel, and
  6. C. Roland Wolf
  1. TaconicArtemis, Koeln, Germany (N.S., A.R., S.B.); CXR Biosciences Limited, Dundee, United Kingdom (Y.K., C.R.W.); Cancer Research UK Molecular Pharmacology Unit, Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom (C.R.W.); and Division of Cancer Research, Medical Research Institute, Level 9, Jacqui Wood Cancer Centre, Ninewells Hospital & Medical School, University of Dundee, Dundee, United Kingdom (L.C.).
  1. Address correspondence to:
    Dr. Nico Scheer, TaconicArtemis, Neurather Ring 1, 51063 Koeln, Germany. E-mail: nico.scheer{at}taconicartemis.com
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Research ArticleArticle

Cyp2c Knockout and CYP2C9 Humanized Mice

Nico Scheer, Yury Kapelyukh, Lynsey Chatham, Anja Rode, Sandra Buechel and C. Roland Wolf
Molecular Pharmacology December 1, 2012, 82 (6) 1022-1029; DOI: https://doi.org/10.1124/mol.112.080036
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