Research ArticleArticle
Betulinic Acid Decreases Specificity Protein 1 (Sp1) Level via Increasing the Sumoylation of Sp1 to Inhibit Lung Cancer Growth
Tsung-I. Hsu, Mei-Chun Wang, Szu-Yu Chen, Shih-Ting Huang, Yu-Min Yeh, Wu-Chou Su, Wen-Chang Chang and Jan-Jong Hung
Molecular Pharmacology December 2012, 82 (6) 1115-1128; DOI: https://doi.org/10.1124/mol.112.078485
Tsung-I. Hsu
Institute of Basic Medical Sciences (T.-I.H.) and Department of Pharmacology (M.C.W., S.-T.H., W.-C.C., J.J.H.), College of Medicine, Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology (S.-Y.C., W.-C.C., J.-J.H.), Department of Internal Medicine, College of Medicine (Y.-M.Y., W.-C.S.), and Center for Infectious Disease and Signal Transduction Research (W.-C.C., J.-J.H.), National Cheng Kung University, Tainan, Taiwan; and Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan (W.-C.C.)
Mei-Chun Wang
Institute of Basic Medical Sciences (T.-I.H.) and Department of Pharmacology (M.C.W., S.-T.H., W.-C.C., J.J.H.), College of Medicine, Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology (S.-Y.C., W.-C.C., J.-J.H.), Department of Internal Medicine, College of Medicine (Y.-M.Y., W.-C.S.), and Center for Infectious Disease and Signal Transduction Research (W.-C.C., J.-J.H.), National Cheng Kung University, Tainan, Taiwan; and Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan (W.-C.C.)
Szu-Yu Chen
Institute of Basic Medical Sciences (T.-I.H.) and Department of Pharmacology (M.C.W., S.-T.H., W.-C.C., J.J.H.), College of Medicine, Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology (S.-Y.C., W.-C.C., J.-J.H.), Department of Internal Medicine, College of Medicine (Y.-M.Y., W.-C.S.), and Center for Infectious Disease and Signal Transduction Research (W.-C.C., J.-J.H.), National Cheng Kung University, Tainan, Taiwan; and Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan (W.-C.C.)
Shih-Ting Huang
Institute of Basic Medical Sciences (T.-I.H.) and Department of Pharmacology (M.C.W., S.-T.H., W.-C.C., J.J.H.), College of Medicine, Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology (S.-Y.C., W.-C.C., J.-J.H.), Department of Internal Medicine, College of Medicine (Y.-M.Y., W.-C.S.), and Center for Infectious Disease and Signal Transduction Research (W.-C.C., J.-J.H.), National Cheng Kung University, Tainan, Taiwan; and Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan (W.-C.C.)
Yu-Min Yeh
Institute of Basic Medical Sciences (T.-I.H.) and Department of Pharmacology (M.C.W., S.-T.H., W.-C.C., J.J.H.), College of Medicine, Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology (S.-Y.C., W.-C.C., J.-J.H.), Department of Internal Medicine, College of Medicine (Y.-M.Y., W.-C.S.), and Center for Infectious Disease and Signal Transduction Research (W.-C.C., J.-J.H.), National Cheng Kung University, Tainan, Taiwan; and Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan (W.-C.C.)
Wu-Chou Su
Institute of Basic Medical Sciences (T.-I.H.) and Department of Pharmacology (M.C.W., S.-T.H., W.-C.C., J.J.H.), College of Medicine, Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology (S.-Y.C., W.-C.C., J.-J.H.), Department of Internal Medicine, College of Medicine (Y.-M.Y., W.-C.S.), and Center for Infectious Disease and Signal Transduction Research (W.-C.C., J.-J.H.), National Cheng Kung University, Tainan, Taiwan; and Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan (W.-C.C.)
Wen-Chang Chang
Institute of Basic Medical Sciences (T.-I.H.) and Department of Pharmacology (M.C.W., S.-T.H., W.-C.C., J.J.H.), College of Medicine, Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology (S.-Y.C., W.-C.C., J.-J.H.), Department of Internal Medicine, College of Medicine (Y.-M.Y., W.-C.S.), and Center for Infectious Disease and Signal Transduction Research (W.-C.C., J.-J.H.), National Cheng Kung University, Tainan, Taiwan; and Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan (W.-C.C.)
Jan-Jong Hung
Institute of Basic Medical Sciences (T.-I.H.) and Department of Pharmacology (M.C.W., S.-T.H., W.-C.C., J.J.H.), College of Medicine, Institute of Bioinformatics and Biosignal Transduction, College of Bioscience and Biotechnology (S.-Y.C., W.-C.C., J.-J.H.), Department of Internal Medicine, College of Medicine (Y.-M.Y., W.-C.S.), and Center for Infectious Disease and Signal Transduction Research (W.-C.C., J.-J.H.), National Cheng Kung University, Tainan, Taiwan; and Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan (W.-C.C.)
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Research ArticleArticle
Betulinic Acid Attenuates Sp1-Regulated CCNA2 in Lung Cancer
Tsung-I. Hsu, Mei-Chun Wang, Szu-Yu Chen, Shih-Ting Huang, Yu-Min Yeh, Wu-Chou Su, Wen-Chang Chang and Jan-Jong Hung
Molecular Pharmacology December 1, 2012, 82 (6) 1115-1128; DOI: https://doi.org/10.1124/mol.112.078485
Research ArticleArticle
Betulinic Acid Attenuates Sp1-Regulated CCNA2 in Lung Cancer
Tsung-I. Hsu, Mei-Chun Wang, Szu-Yu Chen, Shih-Ting Huang, Yu-Min Yeh, Wu-Chou Su, Wen-Chang Chang and Jan-Jong Hung
Molecular Pharmacology December 1, 2012, 82 (6) 1115-1128; DOI: https://doi.org/10.1124/mol.112.078485
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