Table of Contents

Articles

• You have access

  CB₁ Receptor Allosteric Modulators Display Both Agonist and Signaling Pathway Specificity

  Gemma L. Baillie, James G. Horswill, Sharon Anavi-Goffer, Patricia H. Reggio, Daniele Bolognini, Mary E. Abood, Sean McAllister, Phillip G. Strange, Gary J. Stephens, Roger G. Pertwee and Ruth A. Ross

  Molecular Pharmacology February 2013, 83 (2) 322-338; DOI: https://doi.org/10.1124/mol.112.080879
• You have access

  Enhanced Degradation of Dihydrofolate Reductase through Inhibition of NAD Kinase by Nicotinamide Analogs

  Yi-Ching Hsieh, Philip Tedeschi, Rialnat AdeBisi Lawal, Debabrata Banerjee, Kathleen Scotto, John E. Kerrigan, Kuo-Chieh Lee, Nadine Johnson-Farley, Joseph R. Bertino and Emine Ercikan Abali

  Molecular Pharmacology February 2013, 83 (2) 339-353; DOI: https://doi.org/10.1124/mol.112.080218
• You have access

  Noncompetitive, Voltage-Dependent NMDA Receptor Antagonism by Hydrophobic Anions

  Andrew J. Linsenbardt, Mariangela Chisari, Andrew Yu, Hong-Jin Shu, Charles F. Zorumski and Steven Mennerick

  Molecular Pharmacology February 2013, 83 (2) 354-366; DOI: https://doi.org/10.1124/mol.112.081794
• You have access

  Obtusilactone B from Machilus Thunbergii Targets Barrier-to-Autointegration Factor to Treat Cancer

  Wanil Kim, Ha-Na Lyu, Hyun-Sook Kwon, Ye Seul Kim, Kyung-Ha Lee, Do-Yeon Kim, Goutam Chakraborty, Kwan Yong Choi, Ho Sup Yoon and Kyong-Tai Kim

  Molecular Pharmacology February 2013, 83 (2) 367-376; DOI: https://doi.org/10.1124/mol.112.082578
• You have access

  Induction of Multidrug Resistance Transporter ABCG2 by Prolactin in Human Breast Cancer Cells

  Alex Man Lai Wu, Pooja Dalvi, Xiaoli Lu, Mingdong Yang, David S. Riddick, Jason Matthews, Charles V. Clevenger, Douglas D. Ross, Patricia A. Harper and Shinya Ito

  Molecular Pharmacology February 2013, 83 (2) 377-388; DOI: https://doi.org/10.1124/mol.112.082362
• You have access

  Functional Characterization of Three Mouse Formyl Peptide Receptors

  Hui-Qiong He, Dan Liao, Zhen-Guo Wang, Zhong-Li Wang, Hu-Chen Zhou, Ming-Wei Wang and Richard D. Ye

  Molecular Pharmacology February 2013, 83 (2) 389-398; DOI: https://doi.org/10.1124/mol.112.081315
• You have access

  MicroRNA-145 Post-transcriptionally Regulates the Expression and Function of P-glycoprotein in Intestinal Epithelial Cells

  Kenji Ikemura, Misato Yamamoto, Saori Miyazaki, Hideki Mizutani, Takuya Iwamoto and Masahiro Okuda

  Molecular Pharmacology February 2013, 83 (2) 399-405; DOI: https://doi.org/10.1124/mol.112.081844
• You have access

  Molecular Dissection of Lubeluzole Use–Dependent Block of Voltage-Gated Sodium Channels Discloses New Therapeutic Potentials

  Jean-François Desaphy, Roberta Carbonara, Teresa Costanza, Giovanni Lentini, Maria Maddalena Cavalluzzi, Claudio Bruno, Carlo Franchini and Diana Conte Camerino

  Molecular Pharmacology February 2013, 83 (2) 406-415; DOI: https://doi.org/10.1124/mol.112.080804
• You have access

  Conformational Dynamics of Kir3.1/Kir3.2 Channel Activation Via δ-Opioid Receptors

  Melissa Richard-Lalonde, Karim Nagi, Nicolas Audet, Rory Sleno, Mohammad Amraei, Mireille Hogue, Gianfranco Balboni, Peter W. Schiller, Michel Bouvier, Terence E. Hébert and Graciela Pineyro

  Molecular Pharmacology February 2013, 83 (2) 416-428; DOI: https://doi.org/10.1124/mol.112.081950
• You have access

  Canonical Transient Receptor Channel 5 (TRPC5) and TRPC1/4 Contribute to Seizure and Excitotoxicity by Distinct Cellular Mechanisms

  Kevin D. Phelan, U Thaung Shwe, Joel Abramowitz, Hong Wu, Sung W. Rhee, Matthew D. Howell, Paul E. Gottschall, Marc Freichel, Veit Flockerzi, Lutz Birnbaumer and Fang Zheng

  Molecular Pharmacology February 2013, 83 (2) 429-438; DOI: https://doi.org/10.1124/mol.112.082271
• You have access

  Pyrimidine Salvage in Trypanosoma brucei Bloodstream Forms and the Trypanocidal Action of Halogenated Pyrimidines

  Juma A. M. Ali, Darren J. Creek, Karl Burgess, Harriet C. Allison, Mark C. Field, Pascal Mäser and Harry P. De Koning

  Molecular Pharmacology February 2013, 83 (2) 439-453; DOI: https://doi.org/10.1124/mol.112.082321
• You have access

  Targeting the Metastasis Suppressor, NDRG1, Using Novel Iron Chelators: Regulation of Stress Fiber-Mediated Tumor Cell Migration via Modulation of the ROCK1/pMLC2 Signaling Pathway

  Jing Sun, Daohai Zhang, Ying Zheng, Qian Zhao, Minhua Zheng, Zaklina Kovacevic and Des R. Richardson

  Molecular Pharmacology February 2013, 83 (2) 454-469; DOI: https://doi.org/10.1124/mol.112.083097
• You have access

  Mechanism of the Antiproliferative Activity of Some Naphthalene Diimide G-Quadruplex Ligands

  Sonja M. Hampel, Antonella Pepe, Karin M. Greulich-Bode, Sanjay V. Malhotra, Anthony P. Reszka, Sebastian Veith, Petra Boukamp and Stephen Neidle

  Molecular Pharmacology February 2013, 83 (2) 470-480; DOI: https://doi.org/10.1124/mol.112.081075
• You have access

  An Allosteric Mechanism for Drug Block of the Human Cardiac Potassium Channel KCNQ1

  Tao Yang, Jarrod A. Smith, Brenda F. Leake, Charles R. Sanders, Jens Meiler and Dan M. Roden

  Molecular Pharmacology February 2013, 83 (2) 481-489; DOI: https://doi.org/10.1124/mol.112.081513
• You have access

  Identification of Transporters Associated with Etoposide Sensitivity of Stomach Cancer Cell Lines and Methotrexate Sensitivity of Breast Cancer Cell Lines by Quantitative Targeted Absolute Proteomics

  Wataru Obuchi, Sumio Ohtsuki, Yasuo Uchida, Ken Ohmine, Takao Yamori and Tetsuya Terasaki

  Molecular Pharmacology February 2013, 83 (2) 490-500; DOI: https://doi.org/10.1124/mol.112.081083
• You have access

  Bisphenol A Inhibits Voltage-Activated Ca²⁺ Channels in Vitro: Mechanisms and Structural Requirements

  André Deutschmann, Michael Hans, Rainer Meyer, Hanns Häberlein and Dieter Swandulla

  Molecular Pharmacology February 2013, 83 (2) 501-511; DOI: https://doi.org/10.1124/mol.112.081372
• You have access

  Modulation of μ-Opioid Receptor Signaling by RGS19 in SH-SY5Y Cells

  Qin Wang and John R. Traynor

  Molecular Pharmacology February 2013, 83 (2) 512-520; DOI: https://doi.org/10.1124/mol.112.081992
• You have access

  Allosteric Modulation of a Chemogenetically Modified G Protein-Coupled Receptor

  Alaa Abdul-Ridha, J. Robert Lane, Patrick M. Sexton, Meritxell Canals and Arthur Christopoulos

  Molecular Pharmacology February 2013, 83 (2) 521-530; DOI: https://doi.org/10.1124/mol.112.083006
• You have access

  A Novel Semisynthetic Inhibitor of the FRB Domain of Mammalian Target of Rapamycin Blocks Proliferation and Triggers Apoptosis in Chemoresistant Prostate Cancer Cells

  Samy A. F. Morad, Maximilian Schmid, Berthold Büchele, Hans-Ullrich Siehl, Menna El Gafaary, Oleg Lunov, Tatiana Syrovets and Thomas Simmet

  Molecular Pharmacology February 2013, 83 (2) 531-541; DOI: https://doi.org/10.1124/mol.112.081349
• You have access

  Apomorphine Is a Bimodal Modulator of TRPA1 Channels

  Anja Schulze, Beatrice Oehler, Nicole Urban, Michael Schaefer and Kerstin Hill

  Molecular Pharmacology February 2013, 83 (2) 542-551; DOI: https://doi.org/10.1124/mol.112.081976
• You have access

  Ticlopidine, a Cholestatic Liver Injury-Inducible Drug, Causes Dysfunction of Bile Formation via Diminished Biliary Secretion of Phospholipids: Involvement of Biliary-Excreted Glutathione-Conjugated Ticlopidine Metabolites

  Takashi Yoshikado, Tappei Takada, Hideaki Yamamoto, Jeng Kae Tan, Kousei Ito, Tomofumi Santa and Hiroshi Suzuki

  Molecular Pharmacology February 2013, 83 (2) 552-562; DOI: https://doi.org/10.1124/mol.112.081752