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Molecular Pharmacology

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Table of Contents

March 01, 2013; Volume 83,Issue 3

Minireview

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    Writing and Rewriting the Epigenetic Code of Cancer Cells: From Engineered Proteins to Small Molecules
    Pilar Blancafort, Jian Jin and Stephen Frye
    Molecular Pharmacology March 2013, 83 (3) 563-576; DOI: https://doi.org/10.1124/mol.112.080697

Accelerated Communication

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    SKF83959 Is a Potent Allosteric Modulator of Sigma-1 Receptor
    Lin Guo, Jianghao Zhao, Guozhang Jin, Bin Zhao, Guanghui Wang, Ao Zhang and Xuechu Zhen
    Molecular Pharmacology March 2013, 83 (3) 577-586; DOI: https://doi.org/10.1124/mol.112.083840

Articles

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    Regions on Adenylyl Cyclase VII Required for Selective Regulation by the G13 Pathway
    Lily I. Jiang, Jennifer E. Wang and Paul C. Sternweis
    Molecular Pharmacology March 2013, 83 (3) 587-593; DOI: https://doi.org/10.1124/mol.112.082446
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    Identification and Characterization of a Potent Activator of p53-Independent Cellular Senescence via a Small-Molecule Screen for Modifiers of the Integrated Stress Response
    Carly M. Sayers, Ioanna Papandreou, David M. Guttmann, Nancy L. Maas, J. Alan Diehl, Eric S. Witze, Albert C. Koong and Constantinos Koumenis
    Molecular Pharmacology March 2013, 83 (3) 594-604; DOI: https://doi.org/10.1124/mol.112.081810
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    Aryl Hydrocarbon Receptor is a Target of 17-Allylamino-17-demethoxygeldanamycin and Enhances its Anticancer Activity in Lung Adenocarcinoma Cells
    Po-Hung Chen, Jinghua Tsai Chang, Lih-Ann Li, Hui-Ti Tsai, Mei-Ya Shen and Pinpin Lin
    Molecular Pharmacology March 2013, 83 (3) 605-612; DOI: https://doi.org/10.1124/mol.112.081646
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    Vitamin K2 Covalently Binds to Bak and Induces Bak-Mediated Apoptosis
    Satoki Karasawa, Motoki Azuma, Takeshi Kasama, Satoshi Sakamoto, Yasuaki Kabe, Takeshi Imai, Yuki Yamaguchi, Keisuke Miyazawa and Hiroshi Handa
    Molecular Pharmacology March 2013, 83 (3) 613-620; DOI: https://doi.org/10.1124/mol.112.082602
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    Autocrine Endocannabinoid Signaling through CB1 Receptors Potentiates OX1 Orexin Receptor Signaling
    Maria H. Jäntti, Jaana Putula, Pauli M. Turunen, Johnny Näsman, Sami Reijonen, Christer Lindqvist and Jyrki P. Kukkonen
    Molecular Pharmacology March 2013, 83 (3) 621-632; DOI: https://doi.org/10.1124/mol.112.080523
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    Differentiation of Opioid Drug Effects by Hierarchical Multi-Site Phosphorylation
    Sascha Just, Susann Illing, Michelle Trester-Zedlitz, Elaine K. Lau, Sarah J. Kotowski, Elke Miess, Anika Mann, Christian Doll, Jonathan C. Trinidad, Alma L. Burlingame, Mark von Zastrow and Stefan Schulz
    Molecular Pharmacology March 2013, 83 (3) 633-639; DOI: https://doi.org/10.1124/mol.112.082875
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    Control of P2X3 Channel Function by Metabotropic P2Y2 UTP Receptors in Primary Sensory Neurons
    Gary Mo, Jennifer C. Peleshok, Chang-Qing Cao, Alfredo Ribeiro-da-Silva and Philippe Séguéla
    Molecular Pharmacology March 2013, 83 (3) 640-647; DOI: https://doi.org/10.1124/mol.112.082099
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    5-Cholesten-3β,25-Diol 3-Sulfate Decreases Lipid Accumulation in Diet-Induced Nonalcoholic Fatty Liver Disease Mouse Model
    Leyuan Xu, Jin Koung Kim, Qianming Bai, Xin Zhang, Genta Kakiyama, Hae-ki Min, Arun J. Sanyal, William M. Pandak and Shunlin Ren
    Molecular Pharmacology March 2013, 83 (3) 648-658; DOI: https://doi.org/10.1124/mol.112.081505
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    Induced CYP3A4 Expression in Confluent Huh7 Hepatoma Cells as a Result of Decreased Cell Proliferation and Subsequent Pregnane X Receptor Activation
    Louise Sivertsson, Irene Edebert, Margareta Porsmyr Palmertz, Magnus Ingelman-Sundberg and Etienne P. A. Neve
    Molecular Pharmacology March 2013, 83 (3) 659-670; DOI: https://doi.org/10.1124/mol.112.082305
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    Trichostatin A Inhibits Transforming Growth Factor-β–Induced Reactive Oxygen Species Accumulation and Myofibroblast Differentiation via Enhanced NF-E2-Related Factor 2-Antioxidant Response Element Signaling
    Lingling Yang, Mingli Qu, Yao Wang, Haoyun Duan, Peng Chen, Ye Wang, Weiyun Shi, Patrik Danielson and Qingjun Zhou
    Molecular Pharmacology March 2013, 83 (3) 671-680; DOI: https://doi.org/10.1124/mol.112.081059
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    High-Throughput Screening of Small Molecules Identifies Hepcidin Antagonists
    Eileen Fung, Priscilla Sugianto, Jason Hsu, Robert Damoiseaux, Tomas Ganz and Elizabeta Nemeth
    Molecular Pharmacology March 2013, 83 (3) 681-690; DOI: https://doi.org/10.1124/mol.112.083428
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    Smoothened Is a Fully Competent Activator of the Heterotrimeric G Protein Gi
    Feng Shen, Lan Cheng, Andrew E. Douglas, Natalia A. Riobo and David R. Manning
    Molecular Pharmacology March 2013, 83 (3) 691-697; DOI: https://doi.org/10.1124/mol.112.082511
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    Effects on Gene Expression in Rat Liver after Administration of RXR Agonists: UAB30, 4-Methyl-UAB30, and Targretin (Bexarotene)
    Peter T. Vedell, Yan Lu, Clinton J. Grubbs, Yuxin Yin, Hui Jiang, Kirby I. Bland, Donald D. Muccio, Dusica Cvetkovic, Ming You and Ronald Lubet
    Molecular Pharmacology March 2013, 83 (3) 698-708; DOI: https://doi.org/10.1124/mol.112.082404
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    Direct Transcriptional Regulation of Human Hepatic Cytochrome P450 3A4 (CYP3A4) by Peroxisome Proliferator–Activated Receptor Alpha (PPARα)
    Maria Thomas, Oliver Burk, Britta Klumpp, Benjamin A. Kandel, Georg Damm, Thomas S. Weiss, Kathrin Klein, Matthias Schwab and Ulrich M. Zanger
    Molecular Pharmacology March 2013, 83 (3) 709-718; DOI: https://doi.org/10.1124/mol.112.082503

Erratum

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    Correction to “Small-Molecule Targeting of Proliferating Cell Nuclear Antigen Chromatin Association Inhibits Tumor Cell Growth”
    Molecular Pharmacology March 2013, 83 (3) 719; DOI: https://doi.org/10.1124/mol.112.03er13
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In this issue

Molecular Pharmacology: 83 (3)
Molecular Pharmacology
Vol. 83, Issue 3
1 Mar 2013
  • Table of Contents
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  • SB-431542 Is a Potent and Specific Inhibitor of Transforming Growth Factor-β Superfamily Type I Activin Receptor-Like Kinase (ALK) Receptors ALK4, ALK5, and ALK7
  • The G-Protein-Coupled Receptors in the Human Genome Form Five Main Families. Phylogenetic Analysis, Paralogon Groups, and Fingerprints
  • Pharmacological Properties of Y-27632, a Specific Inhibitor of Rho-Associated Kinases
  • Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.
  • The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of CYP3A4 by Rifampicin through a Distal Enhancer Module
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