Research ArticleArticle
Vitamin K2 Covalently Binds to Bak and Induces Bak-Mediated Apoptosis
Satoki Karasawa, Motoki Azuma, Takeshi Kasama, Satoshi Sakamoto, Yasuaki Kabe, Takeshi Imai, Yuki Yamaguchi, Keisuke Miyazawa and Hiroshi Handa
Molecular Pharmacology March 2013, 83 (3) 613-620; DOI: https://doi.org/10.1124/mol.112.082602
Satoki Karasawa
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
Motoki Azuma
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
Takeshi Kasama
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
Satoshi Sakamoto
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
Yasuaki Kabe
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
Takeshi Imai
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
Yuki Yamaguchi
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
Keisuke Miyazawa
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
Hiroshi Handa
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)

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In this issue
Research ArticleArticle
Bak as a Molecular Target of Vitamin K2-Induced Apoptosis
Satoki Karasawa, Motoki Azuma, Takeshi Kasama, Satoshi Sakamoto, Yasuaki Kabe, Takeshi Imai, Yuki Yamaguchi, Keisuke Miyazawa and Hiroshi Handa
Molecular Pharmacology March 1, 2013, 83 (3) 613-620; DOI: https://doi.org/10.1124/mol.112.082602
Research ArticleArticle
Bak as a Molecular Target of Vitamin K2-Induced Apoptosis
Satoki Karasawa, Motoki Azuma, Takeshi Kasama, Satoshi Sakamoto, Yasuaki Kabe, Takeshi Imai, Yuki Yamaguchi, Keisuke Miyazawa and Hiroshi Handa
Molecular Pharmacology March 1, 2013, 83 (3) 613-620; DOI: https://doi.org/10.1124/mol.112.082602
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