Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Molecular Pharmacology
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Molecular Pharmacology

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit molpharm on Facebook
  • Follow molpharm on Twitter
  • Follow molpharm on LinkedIn
Research ArticleArticle

Vitamin K2 Covalently Binds to Bak and Induces Bak-Mediated Apoptosis

Satoki Karasawa, Motoki Azuma, Takeshi Kasama, Satoshi Sakamoto, Yasuaki Kabe, Takeshi Imai, Yuki Yamaguchi, Keisuke Miyazawa and Hiroshi Handa
Molecular Pharmacology March 2013, 83 (3) 613-620; DOI: https://doi.org/10.1124/mol.112.082602
Satoki Karasawa
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Motoki Azuma
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Takeshi Kasama
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Satoshi Sakamoto
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yasuaki Kabe
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Takeshi Imai
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yuki Yamaguchi
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Keisuke Miyazawa
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hiroshi Handa
Department of Biological Information, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, Yokohama, Japan (S.K., M.A., S.S., Y.Y., H.H.); Instrumental Analysis Research Division, Research Center for Medical and Dental Sciences, Tokyo Medical and Dental University, Tokyo, Japan (T.K.); Department of Biochemistry, School of Medicine, Keio University, Tokyo, Japan (Y.K.); Biofrontier Center, Tokyo Institute of Technology, Yokohama, Japan (T.I.); Department of Biochemistry, Tokyo Medical University, Tokyo, Japan (K.M.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF + SI
  • PDF
Loading

MolPharm articles become freely available 12 months after publication, and remain freely available for 5 years. 

Non-open access articles that fall outside this five year window are available only to institutional subscribers and current ASPET members, or through the article purchase feature at the bottom of the page. 

 

  • Click here for information on institutional subscriptions.
  • Click here for information on individual ASPET membership.

 

Log in using your username and password

Forgot your user name or password?

Purchase access

You may purchase access to this article. This will require you to create an account if you don't already have one.
PreviousNext
Back to top

In this issue

Molecular Pharmacology: 83 (3)
Molecular Pharmacology
Vol. 83, Issue 3
1 Mar 2013
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Molecular Pharmacology article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Vitamin K2 Covalently Binds to Bak and Induces Bak-Mediated Apoptosis
(Your Name) has forwarded a page to you from Molecular Pharmacology
(Your Name) thought you would be interested in this article in Molecular Pharmacology.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Research ArticleArticle

Bak as a Molecular Target of Vitamin K2-Induced Apoptosis

Satoki Karasawa, Motoki Azuma, Takeshi Kasama, Satoshi Sakamoto, Yasuaki Kabe, Takeshi Imai, Yuki Yamaguchi, Keisuke Miyazawa and Hiroshi Handa
Molecular Pharmacology March 1, 2013, 83 (3) 613-620; DOI: https://doi.org/10.1124/mol.112.082602

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Research ArticleArticle

Bak as a Molecular Target of Vitamin K2-Induced Apoptosis

Satoki Karasawa, Motoki Azuma, Takeshi Kasama, Satoshi Sakamoto, Yasuaki Kabe, Takeshi Imai, Yuki Yamaguchi, Keisuke Miyazawa and Hiroshi Handa
Molecular Pharmacology March 1, 2013, 83 (3) 613-620; DOI: https://doi.org/10.1124/mol.112.082602
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF + SI
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • Analgesic Effects and Mechanisms of Licochalcones
  • Induced Fit Ligand Binding to CYP3A4
  • Englerin A Inhibits T-Type Channels
Show more Articles

Similar Articles

Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About Molecular Pharmacology
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Journal of Pharmacology and Experimental Therapeutics
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0111 (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics