Research ArticleArticle
Somatic Mutations in GRM1 in Cancer Alter Metabotropic Glutamate Receptor 1 Intracellular Localization and Signaling
Jessica L. Esseltine, Melinda D. Willard, Isabella H. Wulur, Mary E. Lajiness, Thomas D. Barber and Stephen S. G. Ferguson
Molecular Pharmacology April 2013, 83 (4) 770-780; DOI: https://doi.org/10.1124/mol.112.081695
Jessica L. Esseltine
Molecular Brain Research Group, Robarts Research Institute and Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada (J.L.E., S.S.G.F.); and Tailored Therapeutics, Eli Lilly and Company, Indianapolis, Indiana (M.D.W., I.H.W., M.E.H., T.D.B.)
Melinda D. Willard
Molecular Brain Research Group, Robarts Research Institute and Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada (J.L.E., S.S.G.F.); and Tailored Therapeutics, Eli Lilly and Company, Indianapolis, Indiana (M.D.W., I.H.W., M.E.H., T.D.B.)
Isabella H. Wulur
Molecular Brain Research Group, Robarts Research Institute and Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada (J.L.E., S.S.G.F.); and Tailored Therapeutics, Eli Lilly and Company, Indianapolis, Indiana (M.D.W., I.H.W., M.E.H., T.D.B.)
Mary E. Lajiness
Molecular Brain Research Group, Robarts Research Institute and Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada (J.L.E., S.S.G.F.); and Tailored Therapeutics, Eli Lilly and Company, Indianapolis, Indiana (M.D.W., I.H.W., M.E.H., T.D.B.)
Thomas D. Barber
Molecular Brain Research Group, Robarts Research Institute and Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada (J.L.E., S.S.G.F.); and Tailored Therapeutics, Eli Lilly and Company, Indianapolis, Indiana (M.D.W., I.H.W., M.E.H., T.D.B.)
Stephen S. G. Ferguson
Molecular Brain Research Group, Robarts Research Institute and Department of Physiology and Pharmacology, University of Western Ontario, London, Ontario, Canada (J.L.E., S.S.G.F.); and Tailored Therapeutics, Eli Lilly and Company, Indianapolis, Indiana (M.D.W., I.H.W., M.E.H., T.D.B.)

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Somatic Mutations in GRM1 Alter Receptor Activity
Jessica L. Esseltine, Melinda D. Willard, Isabella H. Wulur, Mary E. Lajiness, Thomas D. Barber and Stephen S. G. Ferguson
Molecular Pharmacology April 1, 2013, 83 (4) 770-780; DOI: https://doi.org/10.1124/mol.112.081695
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