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Molecular Pharmacology

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Research ArticleArticle

A Receptor Tyrosine Kinase Network Composed of Fibroblast Growth Factor Receptors, Epidermal Growth Factor Receptor, v-erb-b2 Erythroblastic Leukemia Viral Oncogene Homolog 2, and Hepatocyte Growth Factor Receptor Drives Growth and Survival of Head and Neck Squamous Carcinoma Cell Lines

Katherine R. Singleton, Jihye Kim, Trista K. Hinz, Lindsay A. Marek, Matias Casás-Selves, Clark Hatheway, Aik Choon Tan, James DeGregori and Lynn E. Heasley
Molecular Pharmacology April 2013, 83 (4) 882-893; DOI: https://doi.org/10.1124/mol.112.084111
Katherine R. Singleton
Departments of Craniofacial Biology (K.R.S., T.K.H., L.A.M., C.H., L.E.H.), Medicine (J.K., A.C.T.), and Biochemistry and Molecular Genetics (M.C.-S., J.D.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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Jihye Kim
Departments of Craniofacial Biology (K.R.S., T.K.H., L.A.M., C.H., L.E.H.), Medicine (J.K., A.C.T.), and Biochemistry and Molecular Genetics (M.C.-S., J.D.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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Trista K. Hinz
Departments of Craniofacial Biology (K.R.S., T.K.H., L.A.M., C.H., L.E.H.), Medicine (J.K., A.C.T.), and Biochemistry and Molecular Genetics (M.C.-S., J.D.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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Lindsay A. Marek
Departments of Craniofacial Biology (K.R.S., T.K.H., L.A.M., C.H., L.E.H.), Medicine (J.K., A.C.T.), and Biochemistry and Molecular Genetics (M.C.-S., J.D.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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Matias Casás-Selves
Departments of Craniofacial Biology (K.R.S., T.K.H., L.A.M., C.H., L.E.H.), Medicine (J.K., A.C.T.), and Biochemistry and Molecular Genetics (M.C.-S., J.D.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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Clark Hatheway
Departments of Craniofacial Biology (K.R.S., T.K.H., L.A.M., C.H., L.E.H.), Medicine (J.K., A.C.T.), and Biochemistry and Molecular Genetics (M.C.-S., J.D.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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Aik Choon Tan
Departments of Craniofacial Biology (K.R.S., T.K.H., L.A.M., C.H., L.E.H.), Medicine (J.K., A.C.T.), and Biochemistry and Molecular Genetics (M.C.-S., J.D.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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James DeGregori
Departments of Craniofacial Biology (K.R.S., T.K.H., L.A.M., C.H., L.E.H.), Medicine (J.K., A.C.T.), and Biochemistry and Molecular Genetics (M.C.-S., J.D.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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Lynn E. Heasley
Departments of Craniofacial Biology (K.R.S., T.K.H., L.A.M., C.H., L.E.H.), Medicine (J.K., A.C.T.), and Biochemistry and Molecular Genetics (M.C.-S., J.D.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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Article Information

vol. 83 no. 4 882-893
DOI 
https://doi.org/10.1124/mol.112.084111
PubMed 
23371912

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received November 28, 2012
  • Accepted January 31, 2013
  • Published online March 19, 2013.

Article Versions

  • Earlier version (January 31, 2013 - 08:37).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Katherine R. Singleton,
  2. Jihye Kim,
  3. Trista K. Hinz,
  4. Lindsay A. Marek,
  5. Matias Casás-Selves,
  6. Clark Hatheway,
  7. Aik Choon Tan,
  8. James DeGregori, and
  9. Lynn E. Heasley
  1. Departments of Craniofacial Biology (K.R.S., T.K.H., L.A.M., C.H., L.E.H.), Medicine (J.K., A.C.T.), and Biochemistry and Molecular Genetics (M.C.-S., J.D.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
  1. Address correspondence to:
    Katherine R. Singleton, Department of Craniofacial Biology, School of Dental Medicine, University of Colorado Anschutz Medical Campus, Mail Stop 8120, PO Box 6511, Aurora, CO 80045. E-mail: katherine.singleton{at}ucdenver.edu
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Molecular Pharmacology: 83 (4)
Molecular Pharmacology
Vol. 83, Issue 4
1 Apr 2013
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Research ArticleArticle

Synthetic Lethal Relations Identify a RTK Network in HNSCC

Katherine R. Singleton, Jihye Kim, Trista K. Hinz, Lindsay A. Marek, Matias Casás-Selves, Clark Hatheway, Aik Choon Tan, James DeGregori and Lynn E. Heasley
Molecular Pharmacology April 1, 2013, 83 (4) 882-893; DOI: https://doi.org/10.1124/mol.112.084111

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Research ArticleArticle

Synthetic Lethal Relations Identify a RTK Network in HNSCC

Katherine R. Singleton, Jihye Kim, Trista K. Hinz, Lindsay A. Marek, Matias Casás-Selves, Clark Hatheway, Aik Choon Tan, James DeGregori and Lynn E. Heasley
Molecular Pharmacology April 1, 2013, 83 (4) 882-893; DOI: https://doi.org/10.1124/mol.112.084111
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