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Research ArticleArticle

Identification of Functionally Relevant Lysine Residues That Modulate Human Farnesoid X Receptor Activation

An-Qiang Sun, Yuhuan Luo, Donald S. Backos, Shuhua Xu, Natarajan Balasubramaniyan, Philip Reigan and Frederick J. Suchy
Molecular Pharmacology May 2013, 83 (5) 1078-1086; DOI: https://doi.org/10.1124/mol.113.084772
An-Qiang Sun
Department of Pediatrics (A.-Q.S., Y.L., S.X., N.B., F.J.S.) and Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Pharmaceutical Sciences (D.S.B., P.R.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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Yuhuan Luo
Department of Pediatrics (A.-Q.S., Y.L., S.X., N.B., F.J.S.) and Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Pharmaceutical Sciences (D.S.B., P.R.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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Donald S. Backos
Department of Pediatrics (A.-Q.S., Y.L., S.X., N.B., F.J.S.) and Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Pharmaceutical Sciences (D.S.B., P.R.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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Shuhua Xu
Department of Pediatrics (A.-Q.S., Y.L., S.X., N.B., F.J.S.) and Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Pharmaceutical Sciences (D.S.B., P.R.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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Natarajan Balasubramaniyan
Department of Pediatrics (A.-Q.S., Y.L., S.X., N.B., F.J.S.) and Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Pharmaceutical Sciences (D.S.B., P.R.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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Philip Reigan
Department of Pediatrics (A.-Q.S., Y.L., S.X., N.B., F.J.S.) and Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Pharmaceutical Sciences (D.S.B., P.R.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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Frederick J. Suchy
Department of Pediatrics (A.-Q.S., Y.L., S.X., N.B., F.J.S.) and Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Pharmaceutical Sciences (D.S.B., P.R.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
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Article Information

vol. 83 no. 5 1078-1086
DOI 
https://doi.org/10.1124/mol.113.084772
PubMed 
23462506

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received January 2, 2013
  • Accepted March 5, 2013
  • Published online April 15, 2013.

Article Versions

  • Earlier version (March 5, 2013 - 07:17).
  • Earlier version (March 7, 2013 - 06:04).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. An-Qiang Sun,
  2. Yuhuan Luo,
  3. Donald S. Backos,
  4. Shuhua Xu,
  5. Natarajan Balasubramaniyan,
  6. Philip Reigan, and
  7. Frederick J. Suchy
  1. Department of Pediatrics (A.-Q.S., Y.L., S.X., N.B., F.J.S.) and Skaggs School of Pharmacy and Pharmaceutical Sciences, Department of Pharmaceutical Sciences (D.S.B., P.R.), University of Colorado Anschutz Medical Campus, Aurora, Colorado
  1. Address correspondence to:
    An-Qiang Sun, Department of Pediatrics, University of Colorado Denver School of Medicine, Aurora, CO 80045. E-mail: An-Qiang.Sun{at}ucdenver.edu
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Molecular Pharmacology: 83 (5)
Molecular Pharmacology
Vol. 83, Issue 5
1 May 2013
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Research ArticleArticle

Role of Lysine Residues in FXR Activation

An-Qiang Sun, Yuhuan Luo, Donald S. Backos, Shuhua Xu, Natarajan Balasubramaniyan, Philip Reigan and Frederick J. Suchy
Molecular Pharmacology May 1, 2013, 83 (5) 1078-1086; DOI: https://doi.org/10.1124/mol.113.084772

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Research ArticleArticle

Role of Lysine Residues in FXR Activation

An-Qiang Sun, Yuhuan Luo, Donald S. Backos, Shuhua Xu, Natarajan Balasubramaniyan, Philip Reigan and Frederick J. Suchy
Molecular Pharmacology May 1, 2013, 83 (5) 1078-1086; DOI: https://doi.org/10.1124/mol.113.084772
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