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Research ArticleArticle

Mechanisms of Transient Receptor Potential Vanilloid 1 Activation and Sensitization by Allyl Isothiocyanate

Maarten Gees, Yeranddy A. Alpizar, Brett Boonen, Alicia Sanchez, Wouter Everaerts, Andrei Segal, Fenqin Xue, Annelies Janssens, Grzegorz Owsianik, Bernd Nilius, Thomas Voets and Karel Talavera
Molecular Pharmacology September 2013, 84 (3) 325-334; DOI: https://doi.org/10.1124/mol.113.085548
Maarten Gees
Laboratory for Ion Channel Research, Department of Molecular Cell Biology and TRP Research Platform Leuven (TRPLe) (M.G., Y.A.A., B.B., A.Sa., W.E., A.Se., F.X., A.J., G.O., B.N., T.V., K.T.), and Laboratory of Experimental Urology, Department of Development and Regeneration and TRP Research Platform Leuven (TRPLe) (W.E.), KU Leuven, Leuven, Belgium
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Yeranddy A. Alpizar
Laboratory for Ion Channel Research, Department of Molecular Cell Biology and TRP Research Platform Leuven (TRPLe) (M.G., Y.A.A., B.B., A.Sa., W.E., A.Se., F.X., A.J., G.O., B.N., T.V., K.T.), and Laboratory of Experimental Urology, Department of Development and Regeneration and TRP Research Platform Leuven (TRPLe) (W.E.), KU Leuven, Leuven, Belgium
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Brett Boonen
Laboratory for Ion Channel Research, Department of Molecular Cell Biology and TRP Research Platform Leuven (TRPLe) (M.G., Y.A.A., B.B., A.Sa., W.E., A.Se., F.X., A.J., G.O., B.N., T.V., K.T.), and Laboratory of Experimental Urology, Department of Development and Regeneration and TRP Research Platform Leuven (TRPLe) (W.E.), KU Leuven, Leuven, Belgium
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Alicia Sanchez
Laboratory for Ion Channel Research, Department of Molecular Cell Biology and TRP Research Platform Leuven (TRPLe) (M.G., Y.A.A., B.B., A.Sa., W.E., A.Se., F.X., A.J., G.O., B.N., T.V., K.T.), and Laboratory of Experimental Urology, Department of Development and Regeneration and TRP Research Platform Leuven (TRPLe) (W.E.), KU Leuven, Leuven, Belgium
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Wouter Everaerts
Laboratory for Ion Channel Research, Department of Molecular Cell Biology and TRP Research Platform Leuven (TRPLe) (M.G., Y.A.A., B.B., A.Sa., W.E., A.Se., F.X., A.J., G.O., B.N., T.V., K.T.), and Laboratory of Experimental Urology, Department of Development and Regeneration and TRP Research Platform Leuven (TRPLe) (W.E.), KU Leuven, Leuven, Belgium
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Andrei Segal
Laboratory for Ion Channel Research, Department of Molecular Cell Biology and TRP Research Platform Leuven (TRPLe) (M.G., Y.A.A., B.B., A.Sa., W.E., A.Se., F.X., A.J., G.O., B.N., T.V., K.T.), and Laboratory of Experimental Urology, Department of Development and Regeneration and TRP Research Platform Leuven (TRPLe) (W.E.), KU Leuven, Leuven, Belgium
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Fenqin Xue
Laboratory for Ion Channel Research, Department of Molecular Cell Biology and TRP Research Platform Leuven (TRPLe) (M.G., Y.A.A., B.B., A.Sa., W.E., A.Se., F.X., A.J., G.O., B.N., T.V., K.T.), and Laboratory of Experimental Urology, Department of Development and Regeneration and TRP Research Platform Leuven (TRPLe) (W.E.), KU Leuven, Leuven, Belgium
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Annelies Janssens
Laboratory for Ion Channel Research, Department of Molecular Cell Biology and TRP Research Platform Leuven (TRPLe) (M.G., Y.A.A., B.B., A.Sa., W.E., A.Se., F.X., A.J., G.O., B.N., T.V., K.T.), and Laboratory of Experimental Urology, Department of Development and Regeneration and TRP Research Platform Leuven (TRPLe) (W.E.), KU Leuven, Leuven, Belgium
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Grzegorz Owsianik
Laboratory for Ion Channel Research, Department of Molecular Cell Biology and TRP Research Platform Leuven (TRPLe) (M.G., Y.A.A., B.B., A.Sa., W.E., A.Se., F.X., A.J., G.O., B.N., T.V., K.T.), and Laboratory of Experimental Urology, Department of Development and Regeneration and TRP Research Platform Leuven (TRPLe) (W.E.), KU Leuven, Leuven, Belgium
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Bernd Nilius
Laboratory for Ion Channel Research, Department of Molecular Cell Biology and TRP Research Platform Leuven (TRPLe) (M.G., Y.A.A., B.B., A.Sa., W.E., A.Se., F.X., A.J., G.O., B.N., T.V., K.T.), and Laboratory of Experimental Urology, Department of Development and Regeneration and TRP Research Platform Leuven (TRPLe) (W.E.), KU Leuven, Leuven, Belgium
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Thomas Voets
Laboratory for Ion Channel Research, Department of Molecular Cell Biology and TRP Research Platform Leuven (TRPLe) (M.G., Y.A.A., B.B., A.Sa., W.E., A.Se., F.X., A.J., G.O., B.N., T.V., K.T.), and Laboratory of Experimental Urology, Department of Development and Regeneration and TRP Research Platform Leuven (TRPLe) (W.E.), KU Leuven, Leuven, Belgium
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Karel Talavera
Laboratory for Ion Channel Research, Department of Molecular Cell Biology and TRP Research Platform Leuven (TRPLe) (M.G., Y.A.A., B.B., A.Sa., W.E., A.Se., F.X., A.J., G.O., B.N., T.V., K.T.), and Laboratory of Experimental Urology, Department of Development and Regeneration and TRP Research Platform Leuven (TRPLe) (W.E.), KU Leuven, Leuven, Belgium
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Article Information

vol. 84 no. 3 325-334
DOI 
https://doi.org/10.1124/mol.113.085548
PubMed 
23757176

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received February 8, 2013
  • Accepted June 11, 2013
  • Published online August 9, 2013.

Article Versions

  • Earlier version (June 11, 2013 - 06:57).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Maarten Gees,
  2. Yeranddy A. Alpizar,
  3. Brett Boonen,
  4. Alicia Sanchez,
  5. Wouter Everaerts,
  6. Andrei Segal,
  7. Fenqin Xue,
  8. Annelies Janssens,
  9. Grzegorz Owsianik,
  10. Bernd Nilius,
  11. Thomas Voets, and
  12. Karel Talavera
  1. Laboratory for Ion Channel Research, Department of Molecular Cell Biology and TRP Research Platform Leuven (TRPLe) (M.G., Y.A.A., B.B., A.Sa., W.E., A.Se., F.X., A.J., G.O., B.N., T.V., K.T.), and Laboratory of Experimental Urology, Department of Development and Regeneration and TRP Research Platform Leuven (TRPLe) (W.E.), KU Leuven, Leuven, Belgium
  1. Address correspondence to:
    Karel Talavera, Laboratory of Ion Channel Research. Department of Molecular and Cellular Medicine, KU Leuven, Campus Gasthuisberg O&N1 8th floor, bus 802. Herestraat 49, 3000 Leuven, Belgium. E-mail: Karel.talavera{at}med.kuleuven.be
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Molecular Pharmacology: 84 (3)
Molecular Pharmacology
Vol. 84, Issue 3
1 Sep 2013
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Research ArticleArticle

Mechanisms of TRPV1 Modulation by AITC

Maarten Gees, Yeranddy A. Alpizar, Brett Boonen, Alicia Sanchez, Wouter Everaerts, Andrei Segal, Fenqin Xue, Annelies Janssens, Grzegorz Owsianik, Bernd Nilius, Thomas Voets and Karel Talavera
Molecular Pharmacology September 1, 2013, 84 (3) 325-334; DOI: https://doi.org/10.1124/mol.113.085548

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Research ArticleArticle

Mechanisms of TRPV1 Modulation by AITC

Maarten Gees, Yeranddy A. Alpizar, Brett Boonen, Alicia Sanchez, Wouter Everaerts, Andrei Segal, Fenqin Xue, Annelies Janssens, Grzegorz Owsianik, Bernd Nilius, Thomas Voets and Karel Talavera
Molecular Pharmacology September 1, 2013, 84 (3) 325-334; DOI: https://doi.org/10.1124/mol.113.085548
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