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Research ArticleArticle

The Role of Human Equilibrative Nucleoside Transporter 1 on the Cellular Transport of the DNA Methyltransferase Inhibitors 5-Azacytidine and CP-4200 in Human Leukemia Cells

Johanna Hummel-Eisenbeiss, Antje Hascher, Petter-Arnt Hals, Marit Liland Sandvold, Carsten Müller-Tidow, Frank Lyko and Maria Rius
Molecular Pharmacology September 2013, 84 (3) 438-450; DOI: https://doi.org/10.1124/mol.113.086801
Johanna Hummel-Eisenbeiss
Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, Heidelberg, Germany (J.H.-E., F.L., M.R.); German Cancer Consortium (DKTK) (J.H.-E., F.L.) and Department of Medicine, Hematology and Oncology, University of Münster, Münster, Germany (A.H., C.M.-T.); and Clavis Pharma, Oslo, Norway (P.-A.H., M.L.S.)
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Antje Hascher
Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, Heidelberg, Germany (J.H.-E., F.L., M.R.); German Cancer Consortium (DKTK) (J.H.-E., F.L.) and Department of Medicine, Hematology and Oncology, University of Münster, Münster, Germany (A.H., C.M.-T.); and Clavis Pharma, Oslo, Norway (P.-A.H., M.L.S.)
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Petter-Arnt Hals
Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, Heidelberg, Germany (J.H.-E., F.L., M.R.); German Cancer Consortium (DKTK) (J.H.-E., F.L.) and Department of Medicine, Hematology and Oncology, University of Münster, Münster, Germany (A.H., C.M.-T.); and Clavis Pharma, Oslo, Norway (P.-A.H., M.L.S.)
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Marit Liland Sandvold
Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, Heidelberg, Germany (J.H.-E., F.L., M.R.); German Cancer Consortium (DKTK) (J.H.-E., F.L.) and Department of Medicine, Hematology and Oncology, University of Münster, Münster, Germany (A.H., C.M.-T.); and Clavis Pharma, Oslo, Norway (P.-A.H., M.L.S.)
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Carsten Müller-Tidow
Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, Heidelberg, Germany (J.H.-E., F.L., M.R.); German Cancer Consortium (DKTK) (J.H.-E., F.L.) and Department of Medicine, Hematology and Oncology, University of Münster, Münster, Germany (A.H., C.M.-T.); and Clavis Pharma, Oslo, Norway (P.-A.H., M.L.S.)
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Frank Lyko
Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, Heidelberg, Germany (J.H.-E., F.L., M.R.); German Cancer Consortium (DKTK) (J.H.-E., F.L.) and Department of Medicine, Hematology and Oncology, University of Münster, Münster, Germany (A.H., C.M.-T.); and Clavis Pharma, Oslo, Norway (P.-A.H., M.L.S.)
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Maria Rius
Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, Heidelberg, Germany (J.H.-E., F.L., M.R.); German Cancer Consortium (DKTK) (J.H.-E., F.L.) and Department of Medicine, Hematology and Oncology, University of Münster, Münster, Germany (A.H., C.M.-T.); and Clavis Pharma, Oslo, Norway (P.-A.H., M.L.S.)
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Article Information

vol. 84 no. 3 438-450
DOI 
https://doi.org/10.1124/mol.113.086801
PubMed 
23814180

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received April 15, 2013
  • Accepted June 24, 2013
  • Published online August 9, 2013.

Article Versions

  • Earlier version (June 28, 2013 - 08:29).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Johanna Hummel-Eisenbeiss,
  2. Antje Hascher,
  3. Petter-Arnt Hals,
  4. Marit Liland Sandvold,
  5. Carsten Müller-Tidow,
  6. Frank Lyko, and
  7. Maria Rius
  1. Division of Epigenetics, DKFZ-ZMBH Alliance, German Cancer Research Center, Heidelberg, Germany (J.H.-E., F.L., M.R.); German Cancer Consortium (DKTK) (J.H.-E., F.L.) and Department of Medicine, Hematology and Oncology, University of Münster, Münster, Germany (A.H., C.M.-T.); and Clavis Pharma, Oslo, Norway (P.-A.H., M.L.S.)
  1. Address correspondence to:
    Dr. Maria Rius, German Cancer Research Center, Im Neuenheimer Feld 580, 69120 Heidelberg, Germany. E-mail: m.rius{at}dkfz.de
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Molecular Pharmacology: 84 (3)
Molecular Pharmacology
Vol. 84, Issue 3
1 Sep 2013
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Research ArticleArticle

5-Azacytidine and CP-4200 in Leukemia Cells

Johanna Hummel-Eisenbeiss, Antje Hascher, Petter-Arnt Hals, Marit Liland Sandvold, Carsten Müller-Tidow, Frank Lyko and Maria Rius
Molecular Pharmacology September 1, 2013, 84 (3) 438-450; DOI: https://doi.org/10.1124/mol.113.086801

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Research ArticleArticle

5-Azacytidine and CP-4200 in Leukemia Cells

Johanna Hummel-Eisenbeiss, Antje Hascher, Petter-Arnt Hals, Marit Liland Sandvold, Carsten Müller-Tidow, Frank Lyko and Maria Rius
Molecular Pharmacology September 1, 2013, 84 (3) 438-450; DOI: https://doi.org/10.1124/mol.113.086801
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