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Acetaminophen Modulates P-Glycoprotein Functional Expression at the Blood-Brain Barrier by a Constitutive Androstane Receptor–Dependent Mechanism

Lauren M. Slosky, Brandon J. Thompson, Lucy Sanchez-Covarrubias, Yifeng Zhang, Mei-Li Laracuente, Todd W. Vanderah, Patrick T. Ronaldson and Thomas P. Davis
Molecular Pharmacology November 2013, 84 (5) 774-786; DOI: https://doi.org/10.1124/mol.113.086298

Article Information

vol. 84 no. 5 774-786
DOI 
https://doi.org/10.1124/mol.113.086298
PubMed 
24019224
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received March 13, 2013
  • Accepted September 9, 2013
  • Published online October 7, 2013.

Article Versions

Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Lauren M. Slosky,
  2. Brandon J. Thompson,
  3. Lucy Sanchez-Covarrubias,
  4. Yifeng Zhang,
  5. Mei-Li Laracuente,
  6. Todd W. Vanderah,
  7. Patrick T. Ronaldson, and
  8. Thomas P. Davis
  1. Department of Medical Pharmacology, University of Arizona College of Medicine, Tucson, Arizona
  1. Address correspondence to:
    Lauren M. Slosky, Department of Pharmacology, College of Medicine, University of Arizona, 1501 N. Campbell Ave., P.O. Box 245050, Tucson, AZ 85724-5050. E-mail: lslosky{at}email.arizona.edu
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APAP Modulates P-gp at the BBB and Morphine Analgesia

Lauren M. Slosky, Brandon J. Thompson, Lucy Sanchez-Covarrubias, Yifeng Zhang, Mei-Li Laracuente, Todd W. Vanderah, Patrick T. Ronaldson and Thomas P. Davis
Molecular Pharmacology November 1, 2013, 84 (5) 774-786; DOI: https://doi.org/10.1124/mol.113.086298
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