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Research ArticleArticle

Cross-Modulation and Molecular Interaction at the Cav3.3 Protein between the Endogenous Lipids and the T-Type Calcium Channel Antagonist TTA-A2.

Magali Cazade, Cindy E. Nuss, Isabelle Bidaud, John J. Renger, Victor N. Uebele, Philippe Lory and Jean Chemin
Molecular Pharmacology February 2014, 85 (2) 218-225; DOI: https://doi.org/10.1124/mol.113.089581
Magali Cazade
Institut de Génomique Fonctionnelle, Universités Montpellier 1 and 2, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5203, Institut National de la Santé et de la Recherche Médicale U661, LabEx Ion Channel Science and Therapeutics, Montpellier, France (M.C., I.B., P.L., J.C.); and Department of Neuroscience, Merck Research Laboratories, West Point, Pennsylvania (C.E.N., J.J.R., V.N.U.)
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Cindy E. Nuss
Institut de Génomique Fonctionnelle, Universités Montpellier 1 and 2, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5203, Institut National de la Santé et de la Recherche Médicale U661, LabEx Ion Channel Science and Therapeutics, Montpellier, France (M.C., I.B., P.L., J.C.); and Department of Neuroscience, Merck Research Laboratories, West Point, Pennsylvania (C.E.N., J.J.R., V.N.U.)
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Isabelle Bidaud
Institut de Génomique Fonctionnelle, Universités Montpellier 1 and 2, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5203, Institut National de la Santé et de la Recherche Médicale U661, LabEx Ion Channel Science and Therapeutics, Montpellier, France (M.C., I.B., P.L., J.C.); and Department of Neuroscience, Merck Research Laboratories, West Point, Pennsylvania (C.E.N., J.J.R., V.N.U.)
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John J. Renger
Institut de Génomique Fonctionnelle, Universités Montpellier 1 and 2, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5203, Institut National de la Santé et de la Recherche Médicale U661, LabEx Ion Channel Science and Therapeutics, Montpellier, France (M.C., I.B., P.L., J.C.); and Department of Neuroscience, Merck Research Laboratories, West Point, Pennsylvania (C.E.N., J.J.R., V.N.U.)
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Victor N. Uebele
Institut de Génomique Fonctionnelle, Universités Montpellier 1 and 2, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5203, Institut National de la Santé et de la Recherche Médicale U661, LabEx Ion Channel Science and Therapeutics, Montpellier, France (M.C., I.B., P.L., J.C.); and Department of Neuroscience, Merck Research Laboratories, West Point, Pennsylvania (C.E.N., J.J.R., V.N.U.)
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Philippe Lory
Institut de Génomique Fonctionnelle, Universités Montpellier 1 and 2, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5203, Institut National de la Santé et de la Recherche Médicale U661, LabEx Ion Channel Science and Therapeutics, Montpellier, France (M.C., I.B., P.L., J.C.); and Department of Neuroscience, Merck Research Laboratories, West Point, Pennsylvania (C.E.N., J.J.R., V.N.U.)
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Jean Chemin
Institut de Génomique Fonctionnelle, Universités Montpellier 1 and 2, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5203, Institut National de la Santé et de la Recherche Médicale U661, LabEx Ion Channel Science and Therapeutics, Montpellier, France (M.C., I.B., P.L., J.C.); and Department of Neuroscience, Merck Research Laboratories, West Point, Pennsylvania (C.E.N., J.J.R., V.N.U.)
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Article Information

vol. 85 no. 2 218-225
DOI 
https://doi.org/10.1124/mol.113.089581
PubMed 
24214826

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received September 16, 2013
  • Accepted November 8, 2013
  • Published online December 20, 2013.

Article Versions

  • Earlier version (November 8, 2013 - 11:56).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Magali Cazade,
  2. Cindy E. Nuss,
  3. Isabelle Bidaud,
  4. John J. Renger,
  5. Victor N. Uebele,
  6. Philippe Lory, and
  7. Jean Chemin
  1. Institut de Génomique Fonctionnelle, Universités Montpellier 1 and 2, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 5203, Institut National de la Santé et de la Recherche Médicale U661, LabEx Ion Channel Science and Therapeutics, Montpellier, France (M.C., I.B., P.L., J.C.); and Department of Neuroscience, Merck Research Laboratories, West Point, Pennsylvania (C.E.N., J.J.R., V.N.U.)
  1. Address correspondence to:
    Jean Chemin, Institut de Génomique Fonctionnelle, Universités Montpellier 1 & 2, Centre National de la Recherche Scientifique (CNRS), Unité Mixte de Recherche (UMR) 5203, INSERM U661, LabEx Ion Channel Science and Therapeutics, 141, Rue de la Cardonille, 34094 Montpellier CEDEX 05, France. E-mail: jean.chemin{at}igf.cnrs.fr; or Philippe Lory, Institut de Génomique Fonctionnelle, Universités Montpellier 1 & 2, Centre National de la Recherche Scientifique (CNRS), Unité Mixte de Recherche (UMR) 5203, INSERM U661, LabEx Ion Channel Science and Therapeutics, 141, Rue de la Cardonille, 34094 Montpellier CEDEX 05, France. E-mail: philippe.lory{at}igf.cnrs.fr
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Molecular Pharmacology: 85 (2)
Molecular Pharmacology
Vol. 85, Issue 2
1 Feb 2014
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Research ArticleArticle

Lipids and TTA-A2 Interaction at the Cav3.3 Protein

Magali Cazade, Cindy E. Nuss, Isabelle Bidaud, John J. Renger, Victor N. Uebele, Philippe Lory and Jean Chemin
Molecular Pharmacology February 1, 2014, 85 (2) 218-225; DOI: https://doi.org/10.1124/mol.113.089581

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Research ArticleArticle

Lipids and TTA-A2 Interaction at the Cav3.3 Protein

Magali Cazade, Cindy E. Nuss, Isabelle Bidaud, John J. Renger, Victor N. Uebele, Philippe Lory and Jean Chemin
Molecular Pharmacology February 1, 2014, 85 (2) 218-225; DOI: https://doi.org/10.1124/mol.113.089581
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