Structural and Functional Analysis of G Protein–Coupled Receptor Kinase Inhibition by Paroxetine and a Rationally Designed Analog

Kristoff T. Homan; Emily Wu; Michael W. Wilson; Puja Singh; Scott D. Larsen; John J. G. Tesmer

doi:10.1124/mol.113.089631

Research ArticleArticle

Structural and Functional Analysis of G Protein–Coupled Receptor Kinase Inhibition by Paroxetine and a Rationally Designed Analog

Kristoff T. Homan, Emily Wu, Michael W. Wilson, Puja Singh, Scott D. Larsen and John J. G. Tesmer

Molecular Pharmacology February 2014, 85 (2) 237-248; DOI: https://doi.org/10.1124/mol.113.089631

Kristoff T. Homan

Life Sciences Institute and the Departments of Pharmacology and Biological Sciences (K.T.H., E.W., P.S., J.J.G.T.), and Vahlteich Medicinal Chemistry Core and the Department of Medicinal Chemistry, University of Michigan, Ann Arbor, Michigan (M.W.W., S.D.L.)

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Emily Wu

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Michael W. Wilson

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Puja Singh

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Scott D. Larsen

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John J. G. Tesmer

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Molecular Pharmacology

Vol. 85, Issue 2

1 Feb 2014

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