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Research ArticleArticle

Metformin Represses Drug-Induced Expression of CYP2B6 by Modulating the Constitutive Androstane Receptor Signaling

Hui Yang, Brandy Garzel, Scott Heyward, Timothy Moeller, Paul Shapiro and Hongbing Wang
Molecular Pharmacology February 2014, 85 (2) 249-260; DOI: https://doi.org/10.1124/mol.113.089763

Article Information

vol. 85 no. 2 249-260
DOI 
https://doi.org/10.1124/mol.113.089763
PubMed 
24252946
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received September 18, 2013
  • Accepted November 18, 2013
  • Published online December 20, 2013.

Article Versions

Copyright & Usage 
Copyright © 2013 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Hui Yang,
  2. Brandy Garzel,
  3. Scott Heyward,
  4. Timothy Moeller,
  5. Paul Shapiro, and
  6. Hongbing Wang
  1. Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland (H.Y., B.G., P.S., H.W.); and Bioreclamation In Vitro Technologies (S.H., T.M.), Baltimore, Maryland
  1. Address correspondence to:
    Hongbing Wang, Department of Pharmaceutical Sciences, University of Maryland School of Pharmacy, 20 Penn St., Baltimore, MD 21201. E-mail: hwang{at}rx.umaryland.edu
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Metformin Suppresses CYP2B6 Induction by CAR Phosphorylation

Hui Yang, Brandy Garzel, Scott Heyward, Timothy Moeller, Paul Shapiro and Hongbing Wang
Molecular Pharmacology February 1, 2014, 85 (2) 249-260; DOI: https://doi.org/10.1124/mol.113.089763
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