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Index by author

March 01, 2014; Volume 85,Issue 3

A

  1. Ahn, Seungkirl

    1. Regulation of β2-Adrenergic Receptor Function by Conformationally Selective Single-Domain Intrabodies
      Dean P. Staus, Laura M. Wingler, Ryan T. Strachan, Soren G. F. Rasmussen, Els Pardon, Seungkirl Ahn, Jan Steyaert, Brian K. Kobilka and Robert J. Lefkowitz
      Molecular Pharmacology March 2014, 85 (3) 472-481; DOI: https://doi.org/10.1124/mol.113.089516

  2. Aida, Kensuke

    1. Differential Roles of Ubiquitination in the Degradation Mechanism of Cell Surface–Resident Bile Salt Export Pump and Multidrug Resistance–Associated Protein 2
      Kensuke Aida, Hisamitsu Hayashi, Kaori Inamura, Tadahaya Mizuno and Yuichi Sugiyama
      Molecular Pharmacology March 2014, 85 (3) 482-491; DOI: https://doi.org/10.1124/mol.113.091090

  3. Al-Moubarak, Ehab

    1. Recovery of Current through Mutated TASK3 Potassium Channels Underlying Birk Barel Syndrome
      Emma L. Veale, Mustafa Hassan, Yvonne Walsh, Ehab Al-Moubarak and Alistair Mathie
      Molecular Pharmacology March 2014, 85 (3) 397-407; DOI: https://doi.org/10.1124/mol.113.090530

  4. Artaker, Matthias

    1. Pore-Exposed Tyrosine Residues of P-Glycoprotein Are Important Hydrogen-Bonding Partners for Drugs
      Yaprak Dönmez Cakil, Narakorn Khunweeraphong, Zahida Parveen, Diethart Schmid, Matthias Artaker, Gerhard F. Ecker, Harald H. Sitte, Oliver Pusch, Thomas Stockner and Peter Chiba
      Molecular Pharmacology March 2014, 85 (3) 420-428; DOI: https://doi.org/10.1124/mol.113.088526

B

  1. Bazureau, Jean-Pierre

    1. cdc-Like/Dual-Specificity Tyrosine Phosphorylation–Regulated Kinases Inhibitor Leucettine L41 Induces mTOR-Dependent Autophagy: Implication for Alzheimer’s Disease
      Xavier Fant, Emilie Durieu, Gaëtan Chicanne, Bernard Payrastre, Diego Sbrissa, Assia Shisheva, Emmanuelle Limanton, François Carreaux, Jean-Pierre Bazureau and Laurent Meijer
      Molecular Pharmacology March 2014, 85 (3) 441-450; DOI: https://doi.org/10.1124/mol.113.090837

  2. Beijnen, Jos H.

    1. Bcrp1;Mdr1a/b;Mrp2 Combination Knockout Mice: Altered Disposition of the Dietary Carcinogen PhIP (2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine) and Its Genotoxic Metabolites
      Maria L. H. Vlaming, Sebastiaan F. Teunissen, Evita van de Steeg, Anita van Esch, Els Wagenaar, Luc Brunsveld, Tom F. A. de Greef, Hilde Rosing, Jan H. M. Schellens, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology March 2014, 85 (3) 520-530; DOI: https://doi.org/10.1124/mol.113.088823

  3. Berger, Walter

    1. Triapine and a More Potent Dimethyl Derivative Induce Endoplasmic Reticulum Stress in Cancer Cells
      Robert Trondl, Lea S. Flocke, Christian R. Kowol, Petra Heffeter, Ute Jungwirth, Georg E. Mair, Ralf Steinborn, Éva A. Enyedy, Michael A. Jakupec, Walter Berger and Bernhard K. Keppler
      Molecular Pharmacology March 2014, 85 (3) 451-459; DOI: https://doi.org/10.1124/mol.113.090605

  4. Blumer, Joe B.

    1. Activators of G Protein Signaling Exhibit Broad Functionality and Define a Distinct Core Signaling Triad
      Joe B. Blumer and Stephen M. Lanier
      Molecular Pharmacology March 2014, 85 (3) 388-396; DOI: https://doi.org/10.1124/mol.113.090068

  5. Booth, Laurence

    1. Phosphodiesterase 5 Inhibitors Enhance Chemotherapy Killing in Gastrointestinal/Genitourinary Cancer Cells
      Laurence Booth, Jane L. Roberts, Nichola Cruickshanks, Adam Conley, David E. Durrant, Anindita Das, Paul B. Fisher, Rakesh C. Kukreja, Steven Grant, Andrew Poklepovic and Paul Dent
      Molecular Pharmacology March 2014, 85 (3) 408-419; DOI: https://doi.org/10.1124/mol.113.090043

  6. Bouvier, Michel

    1. Quantification of Ligand Bias for Clinically Relevant β2-Adrenergic Receptor Ligands: Implications for Drug Taxonomy
      Emma T. van der Westhuizen, Billy Breton, Arthur Christopoulos and Michel Bouvier
      Molecular Pharmacology March 2014, 85 (3) 492-509; DOI: https://doi.org/10.1124/mol.113.088880

  7. Breton, Billy

    1. Quantification of Ligand Bias for Clinically Relevant β2-Adrenergic Receptor Ligands: Implications for Drug Taxonomy
      Emma T. van der Westhuizen, Billy Breton, Arthur Christopoulos and Michel Bouvier
      Molecular Pharmacology March 2014, 85 (3) 492-509; DOI: https://doi.org/10.1124/mol.113.088880

  8. Brunsveld, Luc

    1. Bcrp1;Mdr1a/b;Mrp2 Combination Knockout Mice: Altered Disposition of the Dietary Carcinogen PhIP (2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine) and Its Genotoxic Metabolites
      Maria L. H. Vlaming, Sebastiaan F. Teunissen, Evita van de Steeg, Anita van Esch, Els Wagenaar, Luc Brunsveld, Tom F. A. de Greef, Hilde Rosing, Jan H. M. Schellens, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology March 2014, 85 (3) 520-530; DOI: https://doi.org/10.1124/mol.113.088823

C

  1. Carreaux, François

    1. cdc-Like/Dual-Specificity Tyrosine Phosphorylation–Regulated Kinases Inhibitor Leucettine L41 Induces mTOR-Dependent Autophagy: Implication for Alzheimer’s Disease
      Xavier Fant, Emilie Durieu, Gaëtan Chicanne, Bernard Payrastre, Diego Sbrissa, Assia Shisheva, Emmanuelle Limanton, François Carreaux, Jean-Pierre Bazureau and Laurent Meijer
      Molecular Pharmacology March 2014, 85 (3) 441-450; DOI: https://doi.org/10.1124/mol.113.090837

  2. Chi, Yuan

    1. 5′-AMP-Activated Protein Kinase Attenuates Adriamycin-Induced Oxidative Podocyte Injury through Thioredoxin-Mediated Suppression of the Apoptosis Signal-Regulating Kinase 1–P38 Signaling Pathway
      Kun Gao, Yuan Chi, Wei Sun, Masayuki Takeda and Jian Yao
      Molecular Pharmacology March 2014, 85 (3) 460-471; DOI: https://doi.org/10.1124/mol.113.089458

  3. Chiba, Peter

    1. Pore-Exposed Tyrosine Residues of P-Glycoprotein Are Important Hydrogen-Bonding Partners for Drugs
      Yaprak Dönmez Cakil, Narakorn Khunweeraphong, Zahida Parveen, Diethart Schmid, Matthias Artaker, Gerhard F. Ecker, Harald H. Sitte, Oliver Pusch, Thomas Stockner and Peter Chiba
      Molecular Pharmacology March 2014, 85 (3) 420-428; DOI: https://doi.org/10.1124/mol.113.088526

  4. Chicanne, Gaëtan

    1. cdc-Like/Dual-Specificity Tyrosine Phosphorylation–Regulated Kinases Inhibitor Leucettine L41 Induces mTOR-Dependent Autophagy: Implication for Alzheimer’s Disease
      Xavier Fant, Emilie Durieu, Gaëtan Chicanne, Bernard Payrastre, Diego Sbrissa, Assia Shisheva, Emmanuelle Limanton, François Carreaux, Jean-Pierre Bazureau and Laurent Meijer
      Molecular Pharmacology March 2014, 85 (3) 441-450; DOI: https://doi.org/10.1124/mol.113.090837

  5. Chow, Jesse

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

  6. Christopoulos, Arthur

    1. Quantification of Ligand Bias for Clinically Relevant β2-Adrenergic Receptor Ligands: Implications for Drug Taxonomy
      Emma T. van der Westhuizen, Billy Breton, Arthur Christopoulos and Michel Bouvier
      Molecular Pharmacology March 2014, 85 (3) 492-509; DOI: https://doi.org/10.1124/mol.113.088880

  7. Conley, Adam

    1. Phosphodiesterase 5 Inhibitors Enhance Chemotherapy Killing in Gastrointestinal/Genitourinary Cancer Cells
      Laurence Booth, Jane L. Roberts, Nichola Cruickshanks, Adam Conley, David E. Durrant, Anindita Das, Paul B. Fisher, Rakesh C. Kukreja, Steven Grant, Andrew Poklepovic and Paul Dent
      Molecular Pharmacology March 2014, 85 (3) 408-419; DOI: https://doi.org/10.1124/mol.113.090043

  8. Cruickshanks, Nichola

    1. Phosphodiesterase 5 Inhibitors Enhance Chemotherapy Killing in Gastrointestinal/Genitourinary Cancer Cells
      Laurence Booth, Jane L. Roberts, Nichola Cruickshanks, Adam Conley, David E. Durrant, Anindita Das, Paul B. Fisher, Rakesh C. Kukreja, Steven Grant, Andrew Poklepovic and Paul Dent
      Molecular Pharmacology March 2014, 85 (3) 408-419; DOI: https://doi.org/10.1124/mol.113.090043

D

  1. Das, Anindita

    1. Phosphodiesterase 5 Inhibitors Enhance Chemotherapy Killing in Gastrointestinal/Genitourinary Cancer Cells
      Laurence Booth, Jane L. Roberts, Nichola Cruickshanks, Adam Conley, David E. Durrant, Anindita Das, Paul B. Fisher, Rakesh C. Kukreja, Steven Grant, Andrew Poklepovic and Paul Dent
      Molecular Pharmacology March 2014, 85 (3) 408-419; DOI: https://doi.org/10.1124/mol.113.090043

  2. de Greef, Tom F. A.

    1. Bcrp1;Mdr1a/b;Mrp2 Combination Knockout Mice: Altered Disposition of the Dietary Carcinogen PhIP (2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine) and Its Genotoxic Metabolites
      Maria L. H. Vlaming, Sebastiaan F. Teunissen, Evita van de Steeg, Anita van Esch, Els Wagenaar, Luc Brunsveld, Tom F. A. de Greef, Hilde Rosing, Jan H. M. Schellens, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology March 2014, 85 (3) 520-530; DOI: https://doi.org/10.1124/mol.113.088823

  3. Dent, Paul

    1. Phosphodiesterase 5 Inhibitors Enhance Chemotherapy Killing in Gastrointestinal/Genitourinary Cancer Cells
      Laurence Booth, Jane L. Roberts, Nichola Cruickshanks, Adam Conley, David E. Durrant, Anindita Das, Paul B. Fisher, Rakesh C. Kukreja, Steven Grant, Andrew Poklepovic and Paul Dent
      Molecular Pharmacology March 2014, 85 (3) 408-419; DOI: https://doi.org/10.1124/mol.113.090043

  4. Dönmez Cakil, Yaprak

    1. Pore-Exposed Tyrosine Residues of P-Glycoprotein Are Important Hydrogen-Bonding Partners for Drugs
      Yaprak Dönmez Cakil, Narakorn Khunweeraphong, Zahida Parveen, Diethart Schmid, Matthias Artaker, Gerhard F. Ecker, Harald H. Sitte, Oliver Pusch, Thomas Stockner and Peter Chiba
      Molecular Pharmacology March 2014, 85 (3) 420-428; DOI: https://doi.org/10.1124/mol.113.088526

  5. Durieu, Emilie

    1. cdc-Like/Dual-Specificity Tyrosine Phosphorylation–Regulated Kinases Inhibitor Leucettine L41 Induces mTOR-Dependent Autophagy: Implication for Alzheimer’s Disease
      Xavier Fant, Emilie Durieu, Gaëtan Chicanne, Bernard Payrastre, Diego Sbrissa, Assia Shisheva, Emmanuelle Limanton, François Carreaux, Jean-Pierre Bazureau and Laurent Meijer
      Molecular Pharmacology March 2014, 85 (3) 441-450; DOI: https://doi.org/10.1124/mol.113.090837

  6. Durrant, David E.

    1. Phosphodiesterase 5 Inhibitors Enhance Chemotherapy Killing in Gastrointestinal/Genitourinary Cancer Cells
      Laurence Booth, Jane L. Roberts, Nichola Cruickshanks, Adam Conley, David E. Durrant, Anindita Das, Paul B. Fisher, Rakesh C. Kukreja, Steven Grant, Andrew Poklepovic and Paul Dent
      Molecular Pharmacology March 2014, 85 (3) 408-419; DOI: https://doi.org/10.1124/mol.113.090043

E

  1. Ecker, Gerhard F.

    1. Pore-Exposed Tyrosine Residues of P-Glycoprotein Are Important Hydrogen-Bonding Partners for Drugs
      Yaprak Dönmez Cakil, Narakorn Khunweeraphong, Zahida Parveen, Diethart Schmid, Matthias Artaker, Gerhard F. Ecker, Harald H. Sitte, Oliver Pusch, Thomas Stockner and Peter Chiba
      Molecular Pharmacology March 2014, 85 (3) 420-428; DOI: https://doi.org/10.1124/mol.113.088526

  2. Enyedy, Éva A.

    1. Triapine and a More Potent Dimethyl Derivative Induce Endoplasmic Reticulum Stress in Cancer Cells
      Robert Trondl, Lea S. Flocke, Christian R. Kowol, Petra Heffeter, Ute Jungwirth, Georg E. Mair, Ralf Steinborn, Éva A. Enyedy, Michael A. Jakupec, Walter Berger and Bernhard K. Keppler
      Molecular Pharmacology March 2014, 85 (3) 451-459; DOI: https://doi.org/10.1124/mol.113.090605

F

  1. Fant, Xavier

    1. cdc-Like/Dual-Specificity Tyrosine Phosphorylation–Regulated Kinases Inhibitor Leucettine L41 Induces mTOR-Dependent Autophagy: Implication for Alzheimer’s Disease
      Xavier Fant, Emilie Durieu, Gaëtan Chicanne, Bernard Payrastre, Diego Sbrissa, Assia Shisheva, Emmanuelle Limanton, François Carreaux, Jean-Pierre Bazureau and Laurent Meijer
      Molecular Pharmacology March 2014, 85 (3) 441-450; DOI: https://doi.org/10.1124/mol.113.090837

  2. Fisher, Paul B.

    1. Phosphodiesterase 5 Inhibitors Enhance Chemotherapy Killing in Gastrointestinal/Genitourinary Cancer Cells
      Laurence Booth, Jane L. Roberts, Nichola Cruickshanks, Adam Conley, David E. Durrant, Anindita Das, Paul B. Fisher, Rakesh C. Kukreja, Steven Grant, Andrew Poklepovic and Paul Dent
      Molecular Pharmacology March 2014, 85 (3) 408-419; DOI: https://doi.org/10.1124/mol.113.090043

  3. Flocke, Lea S.

    1. Triapine and a More Potent Dimethyl Derivative Induce Endoplasmic Reticulum Stress in Cancer Cells
      Robert Trondl, Lea S. Flocke, Christian R. Kowol, Petra Heffeter, Ute Jungwirth, Georg E. Mair, Ralf Steinborn, Éva A. Enyedy, Michael A. Jakupec, Walter Berger and Bernhard K. Keppler
      Molecular Pharmacology March 2014, 85 (3) 451-459; DOI: https://doi.org/10.1124/mol.113.090605

G

  1. Gao, Kun

    1. 5′-AMP-Activated Protein Kinase Attenuates Adriamycin-Induced Oxidative Podocyte Injury through Thioredoxin-Mediated Suppression of the Apoptosis Signal-Regulating Kinase 1–P38 Signaling Pathway
      Kun Gao, Yuan Chi, Wei Sun, Masayuki Takeda and Jian Yao
      Molecular Pharmacology March 2014, 85 (3) 460-471; DOI: https://doi.org/10.1124/mol.113.089458

  2. Genest, Melinda

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

  3. Grant, Steven

    1. Phosphodiesterase 5 Inhibitors Enhance Chemotherapy Killing in Gastrointestinal/Genitourinary Cancer Cells
      Laurence Booth, Jane L. Roberts, Nichola Cruickshanks, Adam Conley, David E. Durrant, Anindita Das, Paul B. Fisher, Rakesh C. Kukreja, Steven Grant, Andrew Poklepovic and Paul Dent
      Molecular Pharmacology March 2014, 85 (3) 408-419; DOI: https://doi.org/10.1124/mol.113.090043

  4. Gusovsky, Fabian

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

H

  1. Hansen, Hans

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

  2. Hassan, Mustafa

    1. Recovery of Current through Mutated TASK3 Potassium Channels Underlying Birk Barel Syndrome
      Emma L. Veale, Mustafa Hassan, Yvonne Walsh, Ehab Al-Moubarak and Alistair Mathie
      Molecular Pharmacology March 2014, 85 (3) 397-407; DOI: https://doi.org/10.1124/mol.113.090530

  3. Hayashi, Hisamitsu

    1. Differential Roles of Ubiquitination in the Degradation Mechanism of Cell Surface–Resident Bile Salt Export Pump and Multidrug Resistance–Associated Protein 2
      Kensuke Aida, Hisamitsu Hayashi, Kaori Inamura, Tadahaya Mizuno and Yuichi Sugiyama
      Molecular Pharmacology March 2014, 85 (3) 482-491; DOI: https://doi.org/10.1124/mol.113.091090

  4. Heffeter, Petra

    1. Triapine and a More Potent Dimethyl Derivative Induce Endoplasmic Reticulum Stress in Cancer Cells
      Robert Trondl, Lea S. Flocke, Christian R. Kowol, Petra Heffeter, Ute Jungwirth, Georg E. Mair, Ralf Steinborn, Éva A. Enyedy, Michael A. Jakupec, Walter Berger and Bernhard K. Keppler
      Molecular Pharmacology March 2014, 85 (3) 451-459; DOI: https://doi.org/10.1124/mol.113.090605

I

  1. Inamura, Kaori

    1. Differential Roles of Ubiquitination in the Degradation Mechanism of Cell Surface–Resident Bile Salt Export Pump and Multidrug Resistance–Associated Protein 2
      Kensuke Aida, Hisamitsu Hayashi, Kaori Inamura, Tadahaya Mizuno and Yuichi Sugiyama
      Molecular Pharmacology March 2014, 85 (3) 482-491; DOI: https://doi.org/10.1124/mol.113.091090

  2. Ishizaka, Sally T.

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

J

  1. Jakupec, Michael A.

    1. Triapine and a More Potent Dimethyl Derivative Induce Endoplasmic Reticulum Stress in Cancer Cells
      Robert Trondl, Lea S. Flocke, Christian R. Kowol, Petra Heffeter, Ute Jungwirth, Georg E. Mair, Ralf Steinborn, Éva A. Enyedy, Michael A. Jakupec, Walter Berger and Bernhard K. Keppler
      Molecular Pharmacology March 2014, 85 (3) 451-459; DOI: https://doi.org/10.1124/mol.113.090605

  2. Jungwirth, Ute

    1. Triapine and a More Potent Dimethyl Derivative Induce Endoplasmic Reticulum Stress in Cancer Cells
      Robert Trondl, Lea S. Flocke, Christian R. Kowol, Petra Heffeter, Ute Jungwirth, Georg E. Mair, Ralf Steinborn, Éva A. Enyedy, Michael A. Jakupec, Walter Berger and Bernhard K. Keppler
      Molecular Pharmacology March 2014, 85 (3) 451-459; DOI: https://doi.org/10.1124/mol.113.090605

K

  1. Kařízková, Julie

    1. Mutation of Cys242 of Human Monoacylglycerol Lipase Disrupts Balanced Hydrolysis of 1- and 2-Monoacylglycerols and Selectively Impairs Inhibitor Potency
      Tuomo Laitinen, Dina Navia-Paldanius, Roosa Rytilahti, Joona J. T. Marjamaa, Julie Kařízková, Teija Parkkari, Tatu Pantsar, Antti Poso, Jarmo T. Laitinen and Juha R. Savinainen
      Molecular Pharmacology March 2014, 85 (3) 510-519; DOI: https://doi.org/10.1124/mol.113.090795

  2. Keppler, Bernhard K.

    1. Triapine and a More Potent Dimethyl Derivative Induce Endoplasmic Reticulum Stress in Cancer Cells
      Robert Trondl, Lea S. Flocke, Christian R. Kowol, Petra Heffeter, Ute Jungwirth, Georg E. Mair, Ralf Steinborn, Éva A. Enyedy, Michael A. Jakupec, Walter Berger and Bernhard K. Keppler
      Molecular Pharmacology March 2014, 85 (3) 451-459; DOI: https://doi.org/10.1124/mol.113.090605

  3. Khunweeraphong, Narakorn

    1. Pore-Exposed Tyrosine Residues of P-Glycoprotein Are Important Hydrogen-Bonding Partners for Drugs
      Yaprak Dönmez Cakil, Narakorn Khunweeraphong, Zahida Parveen, Diethart Schmid, Matthias Artaker, Gerhard F. Ecker, Harald H. Sitte, Oliver Pusch, Thomas Stockner and Peter Chiba
      Molecular Pharmacology March 2014, 85 (3) 420-428; DOI: https://doi.org/10.1124/mol.113.088526

  4. Kobilka, Brian K.

    1. Regulation of β2-Adrenergic Receptor Function by Conformationally Selective Single-Domain Intrabodies
      Dean P. Staus, Laura M. Wingler, Ryan T. Strachan, Soren G. F. Rasmussen, Els Pardon, Seungkirl Ahn, Jan Steyaert, Brian K. Kobilka and Robert J. Lefkowitz
      Molecular Pharmacology March 2014, 85 (3) 472-481; DOI: https://doi.org/10.1124/mol.113.089516

  5. Kowol, Christian R.

    1. Triapine and a More Potent Dimethyl Derivative Induce Endoplasmic Reticulum Stress in Cancer Cells
      Robert Trondl, Lea S. Flocke, Christian R. Kowol, Petra Heffeter, Ute Jungwirth, Georg E. Mair, Ralf Steinborn, Éva A. Enyedy, Michael A. Jakupec, Walter Berger and Bernhard K. Keppler
      Molecular Pharmacology March 2014, 85 (3) 451-459; DOI: https://doi.org/10.1124/mol.113.090605

  6. Kukreja, Rakesh C.

    1. Phosphodiesterase 5 Inhibitors Enhance Chemotherapy Killing in Gastrointestinal/Genitourinary Cancer Cells
      Laurence Booth, Jane L. Roberts, Nichola Cruickshanks, Adam Conley, David E. Durrant, Anindita Das, Paul B. Fisher, Rakesh C. Kukreja, Steven Grant, Andrew Poklepovic and Paul Dent
      Molecular Pharmacology March 2014, 85 (3) 408-419; DOI: https://doi.org/10.1124/mol.113.090043

L

  1. Laitinen, Jarmo T.

    1. Mutation of Cys242 of Human Monoacylglycerol Lipase Disrupts Balanced Hydrolysis of 1- and 2-Monoacylglycerols and Selectively Impairs Inhibitor Potency
      Tuomo Laitinen, Dina Navia-Paldanius, Roosa Rytilahti, Joona J. T. Marjamaa, Julie Kařízková, Teija Parkkari, Tatu Pantsar, Antti Poso, Jarmo T. Laitinen and Juha R. Savinainen
      Molecular Pharmacology March 2014, 85 (3) 510-519; DOI: https://doi.org/10.1124/mol.113.090795

  2. Laitinen, Tuomo

    1. Mutation of Cys242 of Human Monoacylglycerol Lipase Disrupts Balanced Hydrolysis of 1- and 2-Monoacylglycerols and Selectively Impairs Inhibitor Potency
      Tuomo Laitinen, Dina Navia-Paldanius, Roosa Rytilahti, Joona J. T. Marjamaa, Julie Kařízková, Teija Parkkari, Tatu Pantsar, Antti Poso, Jarmo T. Laitinen and Juha R. Savinainen
      Molecular Pharmacology March 2014, 85 (3) 510-519; DOI: https://doi.org/10.1124/mol.113.090795

  3. Lamphier, Marc

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

  4. Lanier, Stephen M.

    1. Activators of G Protein Signaling Exhibit Broad Functionality and Define a Distinct Core Signaling Triad
      Joe B. Blumer and Stephen M. Lanier
      Molecular Pharmacology March 2014, 85 (3) 388-396; DOI: https://doi.org/10.1124/mol.113.090068

  5. Latz, Eicke

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

  6. Lefkowitz, Robert J.

    1. Regulation of β2-Adrenergic Receptor Function by Conformationally Selective Single-Domain Intrabodies
      Dean P. Staus, Laura M. Wingler, Ryan T. Strachan, Soren G. F. Rasmussen, Els Pardon, Seungkirl Ahn, Jan Steyaert, Brian K. Kobilka and Robert J. Lefkowitz
      Molecular Pharmacology March 2014, 85 (3) 472-481; DOI: https://doi.org/10.1124/mol.113.089516

  7. Limanton, Emmanuelle

    1. cdc-Like/Dual-Specificity Tyrosine Phosphorylation–Regulated Kinases Inhibitor Leucettine L41 Induces mTOR-Dependent Autophagy: Implication for Alzheimer’s Disease
      Xavier Fant, Emilie Durieu, Gaëtan Chicanne, Bernard Payrastre, Diego Sbrissa, Assia Shisheva, Emmanuelle Limanton, François Carreaux, Jean-Pierre Bazureau and Laurent Meijer
      Molecular Pharmacology March 2014, 85 (3) 441-450; DOI: https://doi.org/10.1124/mol.113.090837

  8. Liu, Carrie

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

  9. Liu, Diana

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

M

  1. Mair, Georg E.

    1. Triapine and a More Potent Dimethyl Derivative Induce Endoplasmic Reticulum Stress in Cancer Cells
      Robert Trondl, Lea S. Flocke, Christian R. Kowol, Petra Heffeter, Ute Jungwirth, Georg E. Mair, Ralf Steinborn, Éva A. Enyedy, Michael A. Jakupec, Walter Berger and Bernhard K. Keppler
      Molecular Pharmacology March 2014, 85 (3) 451-459; DOI: https://doi.org/10.1124/mol.113.090605

  2. Marjamaa, Joona J. T.

    1. Mutation of Cys242 of Human Monoacylglycerol Lipase Disrupts Balanced Hydrolysis of 1- and 2-Monoacylglycerols and Selectively Impairs Inhibitor Potency
      Tuomo Laitinen, Dina Navia-Paldanius, Roosa Rytilahti, Joona J. T. Marjamaa, Julie Kařízková, Teija Parkkari, Tatu Pantsar, Antti Poso, Jarmo T. Laitinen and Juha R. Savinainen
      Molecular Pharmacology March 2014, 85 (3) 510-519; DOI: https://doi.org/10.1124/mol.113.090795

  3. Mathie, Alistair

    1. Recovery of Current through Mutated TASK3 Potassium Channels Underlying Birk Barel Syndrome
      Emma L. Veale, Mustafa Hassan, Yvonne Walsh, Ehab Al-Moubarak and Alistair Mathie
      Molecular Pharmacology March 2014, 85 (3) 397-407; DOI: https://doi.org/10.1124/mol.113.090530

  4. Meijer, Laurent

    1. cdc-Like/Dual-Specificity Tyrosine Phosphorylation–Regulated Kinases Inhibitor Leucettine L41 Induces mTOR-Dependent Autophagy: Implication for Alzheimer’s Disease
      Xavier Fant, Emilie Durieu, Gaëtan Chicanne, Bernard Payrastre, Diego Sbrissa, Assia Shisheva, Emmanuelle Limanton, François Carreaux, Jean-Pierre Bazureau and Laurent Meijer
      Molecular Pharmacology March 2014, 85 (3) 441-450; DOI: https://doi.org/10.1124/mol.113.090837

  5. Mempel, Thorsten R.

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

  6. Mizuno, Tadahaya

    1. Differential Roles of Ubiquitination in the Degradation Mechanism of Cell Surface–Resident Bile Salt Export Pump and Multidrug Resistance–Associated Protein 2
      Kensuke Aida, Hisamitsu Hayashi, Kaori Inamura, Tadahaya Mizuno and Yuichi Sugiyama
      Molecular Pharmacology March 2014, 85 (3) 482-491; DOI: https://doi.org/10.1124/mol.113.091090

N

  1. Navia-Paldanius, Dina

    1. Mutation of Cys242 of Human Monoacylglycerol Lipase Disrupts Balanced Hydrolysis of 1- and 2-Monoacylglycerols and Selectively Impairs Inhibitor Potency
      Tuomo Laitinen, Dina Navia-Paldanius, Roosa Rytilahti, Joona J. T. Marjamaa, Julie Kařízková, Teija Parkkari, Tatu Pantsar, Antti Poso, Jarmo T. Laitinen and Juha R. Savinainen
      Molecular Pharmacology March 2014, 85 (3) 510-519; DOI: https://doi.org/10.1124/mol.113.090795

P

  1. Pantsar, Tatu

    1. Mutation of Cys242 of Human Monoacylglycerol Lipase Disrupts Balanced Hydrolysis of 1- and 2-Monoacylglycerols and Selectively Impairs Inhibitor Potency
      Tuomo Laitinen, Dina Navia-Paldanius, Roosa Rytilahti, Joona J. T. Marjamaa, Julie Kařízková, Teija Parkkari, Tatu Pantsar, Antti Poso, Jarmo T. Laitinen and Juha R. Savinainen
      Molecular Pharmacology March 2014, 85 (3) 510-519; DOI: https://doi.org/10.1124/mol.113.090795

  2. Pardon, Els

    1. Regulation of β2-Adrenergic Receptor Function by Conformationally Selective Single-Domain Intrabodies
      Dean P. Staus, Laura M. Wingler, Ryan T. Strachan, Soren G. F. Rasmussen, Els Pardon, Seungkirl Ahn, Jan Steyaert, Brian K. Kobilka and Robert J. Lefkowitz
      Molecular Pharmacology March 2014, 85 (3) 472-481; DOI: https://doi.org/10.1124/mol.113.089516

  3. Parkkari, Teija

    1. Mutation of Cys242 of Human Monoacylglycerol Lipase Disrupts Balanced Hydrolysis of 1- and 2-Monoacylglycerols and Selectively Impairs Inhibitor Potency
      Tuomo Laitinen, Dina Navia-Paldanius, Roosa Rytilahti, Joona J. T. Marjamaa, Julie Kařízková, Teija Parkkari, Tatu Pantsar, Antti Poso, Jarmo T. Laitinen and Juha R. Savinainen
      Molecular Pharmacology March 2014, 85 (3) 510-519; DOI: https://doi.org/10.1124/mol.113.090795

  4. Parveen, Zahida

    1. Pore-Exposed Tyrosine Residues of P-Glycoprotein Are Important Hydrogen-Bonding Partners for Drugs
      Yaprak Dönmez Cakil, Narakorn Khunweeraphong, Zahida Parveen, Diethart Schmid, Matthias Artaker, Gerhard F. Ecker, Harald H. Sitte, Oliver Pusch, Thomas Stockner and Peter Chiba
      Molecular Pharmacology March 2014, 85 (3) 420-428; DOI: https://doi.org/10.1124/mol.113.088526

  5. Payrastre, Bernard

    1. cdc-Like/Dual-Specificity Tyrosine Phosphorylation–Regulated Kinases Inhibitor Leucettine L41 Induces mTOR-Dependent Autophagy: Implication for Alzheimer’s Disease
      Xavier Fant, Emilie Durieu, Gaëtan Chicanne, Bernard Payrastre, Diego Sbrissa, Assia Shisheva, Emmanuelle Limanton, François Carreaux, Jean-Pierre Bazureau and Laurent Meijer
      Molecular Pharmacology March 2014, 85 (3) 441-450; DOI: https://doi.org/10.1124/mol.113.090837

  6. Poklepovic, Andrew

    1. Phosphodiesterase 5 Inhibitors Enhance Chemotherapy Killing in Gastrointestinal/Genitourinary Cancer Cells
      Laurence Booth, Jane L. Roberts, Nichola Cruickshanks, Adam Conley, David E. Durrant, Anindita Das, Paul B. Fisher, Rakesh C. Kukreja, Steven Grant, Andrew Poklepovic and Paul Dent
      Molecular Pharmacology March 2014, 85 (3) 408-419; DOI: https://doi.org/10.1124/mol.113.090043

  7. Poso, Antti

    1. Mutation of Cys242 of Human Monoacylglycerol Lipase Disrupts Balanced Hydrolysis of 1- and 2-Monoacylglycerols and Selectively Impairs Inhibitor Potency
      Tuomo Laitinen, Dina Navia-Paldanius, Roosa Rytilahti, Joona J. T. Marjamaa, Julie Kařízková, Teija Parkkari, Tatu Pantsar, Antti Poso, Jarmo T. Laitinen and Juha R. Savinainen
      Molecular Pharmacology March 2014, 85 (3) 510-519; DOI: https://doi.org/10.1124/mol.113.090795

  8. Pusch, Oliver

    1. Pore-Exposed Tyrosine Residues of P-Glycoprotein Are Important Hydrogen-Bonding Partners for Drugs
      Yaprak Dönmez Cakil, Narakorn Khunweeraphong, Zahida Parveen, Diethart Schmid, Matthias Artaker, Gerhard F. Ecker, Harald H. Sitte, Oliver Pusch, Thomas Stockner and Peter Chiba
      Molecular Pharmacology March 2014, 85 (3) 420-428; DOI: https://doi.org/10.1124/mol.113.088526

R

  1. Rasmussen, Soren G. F.

    1. Regulation of β2-Adrenergic Receptor Function by Conformationally Selective Single-Domain Intrabodies
      Dean P. Staus, Laura M. Wingler, Ryan T. Strachan, Soren G. F. Rasmussen, Els Pardon, Seungkirl Ahn, Jan Steyaert, Brian K. Kobilka and Robert J. Lefkowitz
      Molecular Pharmacology March 2014, 85 (3) 472-481; DOI: https://doi.org/10.1124/mol.113.089516

  2. Roberts, Jane L.

    1. Phosphodiesterase 5 Inhibitors Enhance Chemotherapy Killing in Gastrointestinal/Genitourinary Cancer Cells
      Laurence Booth, Jane L. Roberts, Nichola Cruickshanks, Adam Conley, David E. Durrant, Anindita Das, Paul B. Fisher, Rakesh C. Kukreja, Steven Grant, Andrew Poklepovic and Paul Dent
      Molecular Pharmacology March 2014, 85 (3) 408-419; DOI: https://doi.org/10.1124/mol.113.090043

  3. Rose, Jeffrey

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

  4. Rosing, Hilde

    1. Bcrp1;Mdr1a/b;Mrp2 Combination Knockout Mice: Altered Disposition of the Dietary Carcinogen PhIP (2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine) and Its Genotoxic Metabolites
      Maria L. H. Vlaming, Sebastiaan F. Teunissen, Evita van de Steeg, Anita van Esch, Els Wagenaar, Luc Brunsveld, Tom F. A. de Greef, Hilde Rosing, Jan H. M. Schellens, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology March 2014, 85 (3) 520-530; DOI: https://doi.org/10.1124/mol.113.088823

  5. Rowbottom, Christopher

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

  6. Rytilahti, Roosa

    1. Mutation of Cys242 of Human Monoacylglycerol Lipase Disrupts Balanced Hydrolysis of 1- and 2-Monoacylglycerols and Selectively Impairs Inhibitor Potency
      Tuomo Laitinen, Dina Navia-Paldanius, Roosa Rytilahti, Joona J. T. Marjamaa, Julie Kařízková, Teija Parkkari, Tatu Pantsar, Antti Poso, Jarmo T. Laitinen and Juha R. Savinainen
      Molecular Pharmacology March 2014, 85 (3) 510-519; DOI: https://doi.org/10.1124/mol.113.090795

S

  1. Savinainen, Juha R.

    1. Mutation of Cys242 of Human Monoacylglycerol Lipase Disrupts Balanced Hydrolysis of 1- and 2-Monoacylglycerols and Selectively Impairs Inhibitor Potency
      Tuomo Laitinen, Dina Navia-Paldanius, Roosa Rytilahti, Joona J. T. Marjamaa, Julie Kařízková, Teija Parkkari, Tatu Pantsar, Antti Poso, Jarmo T. Laitinen and Juha R. Savinainen
      Molecular Pharmacology March 2014, 85 (3) 510-519; DOI: https://doi.org/10.1124/mol.113.090795

  2. Sbrissa, Diego

    1. cdc-Like/Dual-Specificity Tyrosine Phosphorylation–Regulated Kinases Inhibitor Leucettine L41 Induces mTOR-Dependent Autophagy: Implication for Alzheimer’s Disease
      Xavier Fant, Emilie Durieu, Gaëtan Chicanne, Bernard Payrastre, Diego Sbrissa, Assia Shisheva, Emmanuelle Limanton, François Carreaux, Jean-Pierre Bazureau and Laurent Meijer
      Molecular Pharmacology March 2014, 85 (3) 441-450; DOI: https://doi.org/10.1124/mol.113.090837

  3. Schellens, Jan H. M.

    1. Bcrp1;Mdr1a/b;Mrp2 Combination Knockout Mice: Altered Disposition of the Dietary Carcinogen PhIP (2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine) and Its Genotoxic Metabolites
      Maria L. H. Vlaming, Sebastiaan F. Teunissen, Evita van de Steeg, Anita van Esch, Els Wagenaar, Luc Brunsveld, Tom F. A. de Greef, Hilde Rosing, Jan H. M. Schellens, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology March 2014, 85 (3) 520-530; DOI: https://doi.org/10.1124/mol.113.088823

  4. Schinkel, Alfred H.

    1. Bcrp1;Mdr1a/b;Mrp2 Combination Knockout Mice: Altered Disposition of the Dietary Carcinogen PhIP (2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine) and Its Genotoxic Metabolites
      Maria L. H. Vlaming, Sebastiaan F. Teunissen, Evita van de Steeg, Anita van Esch, Els Wagenaar, Luc Brunsveld, Tom F. A. de Greef, Hilde Rosing, Jan H. M. Schellens, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology March 2014, 85 (3) 520-530; DOI: https://doi.org/10.1124/mol.113.088823

  5. Schmid, Diethart

    1. Pore-Exposed Tyrosine Residues of P-Glycoprotein Are Important Hydrogen-Bonding Partners for Drugs
      Yaprak Dönmez Cakil, Narakorn Khunweeraphong, Zahida Parveen, Diethart Schmid, Matthias Artaker, Gerhard F. Ecker, Harald H. Sitte, Oliver Pusch, Thomas Stockner and Peter Chiba
      Molecular Pharmacology March 2014, 85 (3) 420-428; DOI: https://doi.org/10.1124/mol.113.088526

  6. Shaffer, Christina

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

  7. Shen, Yongchun

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

  8. Shisheva, Assia

    1. cdc-Like/Dual-Specificity Tyrosine Phosphorylation–Regulated Kinases Inhibitor Leucettine L41 Induces mTOR-Dependent Autophagy: Implication for Alzheimer’s Disease
      Xavier Fant, Emilie Durieu, Gaëtan Chicanne, Bernard Payrastre, Diego Sbrissa, Assia Shisheva, Emmanuelle Limanton, François Carreaux, Jean-Pierre Bazureau and Laurent Meijer
      Molecular Pharmacology March 2014, 85 (3) 441-450; DOI: https://doi.org/10.1124/mol.113.090837

  9. Sitte, Harald H.

    1. Pore-Exposed Tyrosine Residues of P-Glycoprotein Are Important Hydrogen-Bonding Partners for Drugs
      Yaprak Dönmez Cakil, Narakorn Khunweeraphong, Zahida Parveen, Diethart Schmid, Matthias Artaker, Gerhard F. Ecker, Harald H. Sitte, Oliver Pusch, Thomas Stockner and Peter Chiba
      Molecular Pharmacology March 2014, 85 (3) 420-428; DOI: https://doi.org/10.1124/mol.113.088526

  10. Spyvee, Mark

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

  11. Staus, Dean P.

    1. Regulation of β2-Adrenergic Receptor Function by Conformationally Selective Single-Domain Intrabodies
      Dean P. Staus, Laura M. Wingler, Ryan T. Strachan, Soren G. F. Rasmussen, Els Pardon, Seungkirl Ahn, Jan Steyaert, Brian K. Kobilka and Robert J. Lefkowitz
      Molecular Pharmacology March 2014, 85 (3) 472-481; DOI: https://doi.org/10.1124/mol.113.089516

  12. Steinborn, Ralf

    1. Triapine and a More Potent Dimethyl Derivative Induce Endoplasmic Reticulum Stress in Cancer Cells
      Robert Trondl, Lea S. Flocke, Christian R. Kowol, Petra Heffeter, Ute Jungwirth, Georg E. Mair, Ralf Steinborn, Éva A. Enyedy, Michael A. Jakupec, Walter Berger and Bernhard K. Keppler
      Molecular Pharmacology March 2014, 85 (3) 451-459; DOI: https://doi.org/10.1124/mol.113.090605

  13. Steyaert, Jan

    1. Regulation of β2-Adrenergic Receptor Function by Conformationally Selective Single-Domain Intrabodies
      Dean P. Staus, Laura M. Wingler, Ryan T. Strachan, Soren G. F. Rasmussen, Els Pardon, Seungkirl Ahn, Jan Steyaert, Brian K. Kobilka and Robert J. Lefkowitz
      Molecular Pharmacology March 2014, 85 (3) 472-481; DOI: https://doi.org/10.1124/mol.113.089516

  14. Stockner, Thomas

    1. Pore-Exposed Tyrosine Residues of P-Glycoprotein Are Important Hydrogen-Bonding Partners for Drugs
      Yaprak Dönmez Cakil, Narakorn Khunweeraphong, Zahida Parveen, Diethart Schmid, Matthias Artaker, Gerhard F. Ecker, Harald H. Sitte, Oliver Pusch, Thomas Stockner and Peter Chiba
      Molecular Pharmacology March 2014, 85 (3) 420-428; DOI: https://doi.org/10.1124/mol.113.088526

  15. Strachan, Ryan T.

    1. Regulation of β2-Adrenergic Receptor Function by Conformationally Selective Single-Domain Intrabodies
      Dean P. Staus, Laura M. Wingler, Ryan T. Strachan, Soren G. F. Rasmussen, Els Pardon, Seungkirl Ahn, Jan Steyaert, Brian K. Kobilka and Robert J. Lefkowitz
      Molecular Pharmacology March 2014, 85 (3) 472-481; DOI: https://doi.org/10.1124/mol.113.089516

  16. Sugiyama, Yuichi

    1. Differential Roles of Ubiquitination in the Degradation Mechanism of Cell Surface–Resident Bile Salt Export Pump and Multidrug Resistance–Associated Protein 2
      Kensuke Aida, Hisamitsu Hayashi, Kaori Inamura, Tadahaya Mizuno and Yuichi Sugiyama
      Molecular Pharmacology March 2014, 85 (3) 482-491; DOI: https://doi.org/10.1124/mol.113.091090

  17. Sun, Wei

    1. 5′-AMP-Activated Protein Kinase Attenuates Adriamycin-Induced Oxidative Podocyte Injury through Thioredoxin-Mediated Suppression of the Apoptosis Signal-Regulating Kinase 1–P38 Signaling Pathway
      Kun Gao, Yuan Chi, Wei Sun, Masayuki Takeda and Jian Yao
      Molecular Pharmacology March 2014, 85 (3) 460-471; DOI: https://doi.org/10.1124/mol.113.089458

T

  1. Takeda, Masayuki

    1. 5′-AMP-Activated Protein Kinase Attenuates Adriamycin-Induced Oxidative Podocyte Injury through Thioredoxin-Mediated Suppression of the Apoptosis Signal-Regulating Kinase 1–P38 Signaling Pathway
      Kun Gao, Yuan Chi, Wei Sun, Masayuki Takeda and Jian Yao
      Molecular Pharmacology March 2014, 85 (3) 460-471; DOI: https://doi.org/10.1124/mol.113.089458

  2. Teunissen, Sebastiaan F.

    1. Bcrp1;Mdr1a/b;Mrp2 Combination Knockout Mice: Altered Disposition of the Dietary Carcinogen PhIP (2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine) and Its Genotoxic Metabolites
      Maria L. H. Vlaming, Sebastiaan F. Teunissen, Evita van de Steeg, Anita van Esch, Els Wagenaar, Luc Brunsveld, Tom F. A. de Greef, Hilde Rosing, Jan H. M. Schellens, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology March 2014, 85 (3) 520-530; DOI: https://doi.org/10.1124/mol.113.088823

  3. Trondl, Robert

    1. Triapine and a More Potent Dimethyl Derivative Induce Endoplasmic Reticulum Stress in Cancer Cells
      Robert Trondl, Lea S. Flocke, Christian R. Kowol, Petra Heffeter, Ute Jungwirth, Georg E. Mair, Ralf Steinborn, Éva A. Enyedy, Michael A. Jakupec, Walter Berger and Bernhard K. Keppler
      Molecular Pharmacology March 2014, 85 (3) 451-459; DOI: https://doi.org/10.1124/mol.113.090605

  4. Twine, Natalie C.

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

V

  1. van der Westhuizen, Emma T.

    1. Quantification of Ligand Bias for Clinically Relevant β2-Adrenergic Receptor Ligands: Implications for Drug Taxonomy
      Emma T. van der Westhuizen, Billy Breton, Arthur Christopoulos and Michel Bouvier
      Molecular Pharmacology March 2014, 85 (3) 492-509; DOI: https://doi.org/10.1124/mol.113.088880

  2. van de Steeg, Evita

    1. Bcrp1;Mdr1a/b;Mrp2 Combination Knockout Mice: Altered Disposition of the Dietary Carcinogen PhIP (2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine) and Its Genotoxic Metabolites
      Maria L. H. Vlaming, Sebastiaan F. Teunissen, Evita van de Steeg, Anita van Esch, Els Wagenaar, Luc Brunsveld, Tom F. A. de Greef, Hilde Rosing, Jan H. M. Schellens, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology March 2014, 85 (3) 520-530; DOI: https://doi.org/10.1124/mol.113.088823

  3. van Esch, Anita

    1. Bcrp1;Mdr1a/b;Mrp2 Combination Knockout Mice: Altered Disposition of the Dietary Carcinogen PhIP (2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine) and Its Genotoxic Metabolites
      Maria L. H. Vlaming, Sebastiaan F. Teunissen, Evita van de Steeg, Anita van Esch, Els Wagenaar, Luc Brunsveld, Tom F. A. de Greef, Hilde Rosing, Jan H. M. Schellens, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology March 2014, 85 (3) 520-530; DOI: https://doi.org/10.1124/mol.113.088823

  4. Veale, Emma L.

    1. Recovery of Current through Mutated TASK3 Potassium Channels Underlying Birk Barel Syndrome
      Emma L. Veale, Mustafa Hassan, Yvonne Walsh, Ehab Al-Moubarak and Alistair Mathie
      Molecular Pharmacology March 2014, 85 (3) 397-407; DOI: https://doi.org/10.1124/mol.113.090530

  5. Vlaming, Maria L. H.

    1. Bcrp1;Mdr1a/b;Mrp2 Combination Knockout Mice: Altered Disposition of the Dietary Carcinogen PhIP (2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine) and Its Genotoxic Metabolites
      Maria L. H. Vlaming, Sebastiaan F. Teunissen, Evita van de Steeg, Anita van Esch, Els Wagenaar, Luc Brunsveld, Tom F. A. de Greef, Hilde Rosing, Jan H. M. Schellens, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology March 2014, 85 (3) 520-530; DOI: https://doi.org/10.1124/mol.113.088823

W

  1. Wagenaar, Els

    1. Bcrp1;Mdr1a/b;Mrp2 Combination Knockout Mice: Altered Disposition of the Dietary Carcinogen PhIP (2-Amino-1-Methyl-6-Phenylimidazo[4,5-b]Pyridine) and Its Genotoxic Metabolites
      Maria L. H. Vlaming, Sebastiaan F. Teunissen, Evita van de Steeg, Anita van Esch, Els Wagenaar, Luc Brunsveld, Tom F. A. de Greef, Hilde Rosing, Jan H. M. Schellens, Jos H. Beijnen and Alfred H. Schinkel
      Molecular Pharmacology March 2014, 85 (3) 520-530; DOI: https://doi.org/10.1124/mol.113.088823

  2. Walsh, Yvonne

    1. Recovery of Current through Mutated TASK3 Potassium Channels Underlying Birk Barel Syndrome
      Emma L. Veale, Mustafa Hassan, Yvonne Walsh, Ehab Al-Moubarak and Alistair Mathie
      Molecular Pharmacology March 2014, 85 (3) 397-407; DOI: https://doi.org/10.1124/mol.113.090530

  3. Wingler, Laura M.

    1. Regulation of β2-Adrenergic Receptor Function by Conformationally Selective Single-Domain Intrabodies
      Dean P. Staus, Laura M. Wingler, Ryan T. Strachan, Soren G. F. Rasmussen, Els Pardon, Seungkirl Ahn, Jan Steyaert, Brian K. Kobilka and Robert J. Lefkowitz
      Molecular Pharmacology March 2014, 85 (3) 472-481; DOI: https://doi.org/10.1124/mol.113.089516

Y

  1. Yang, Hua

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

  2. Yao, Jian

    1. 5′-AMP-Activated Protein Kinase Attenuates Adriamycin-Induced Oxidative Podocyte Injury through Thioredoxin-Mediated Suppression of the Apoptosis Signal-Regulating Kinase 1–P38 Signaling Pathway
      Kun Gao, Yuan Chi, Wei Sun, Masayuki Takeda and Jian Yao
      Molecular Pharmacology March 2014, 85 (3) 460-471; DOI: https://doi.org/10.1124/mol.113.089458

  3. Yu, Melvin

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

Z

  1. Zhao, Yan

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821

  2. Zheng, Wanjun

    1. Novel Small Molecule Inhibitors of TLR7 and TLR9: Mechanism of Action and Efficacy In Vivo
      Marc Lamphier, Wanjun Zheng, Eicke Latz, Mark Spyvee, Hans Hansen, Jeffrey Rose, Melinda Genest, Hua Yang, Christina Shaffer, Yan Zhao, Yongchun Shen, Carrie Liu, Diana Liu, Thorsten R. Mempel, Christopher Rowbottom, Jesse Chow, Natalie C. Twine, Melvin Yu, Fabian Gusovsky and Sally T. Ishizaka
      Molecular Pharmacology March 2014, 85 (3) 429-440; DOI: https://doi.org/10.1124/mol.113.089821
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