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Research ArticleArticle

Differential Roles of Ubiquitination in the Degradation Mechanism of Cell Surface–Resident Bile Salt Export Pump and Multidrug Resistance–Associated Protein 2

Kensuke Aida, Hisamitsu Hayashi, Kaori Inamura, Tadahaya Mizuno and Yuichi Sugiyama
Molecular Pharmacology March 2014, 85 (3) 482-491; DOI: https://doi.org/10.1124/mol.113.091090
Kensuke Aida
Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan (K.A., H.H., K.I., T.M.); and Sugiyama Laboratory, RIKEN Innovation Center, Research Cluster for Innovation, RIKEN, Yokohama, Japan (Y.S.)
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Hisamitsu Hayashi
Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan (K.A., H.H., K.I., T.M.); and Sugiyama Laboratory, RIKEN Innovation Center, Research Cluster for Innovation, RIKEN, Yokohama, Japan (Y.S.)
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Kaori Inamura
Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan (K.A., H.H., K.I., T.M.); and Sugiyama Laboratory, RIKEN Innovation Center, Research Cluster for Innovation, RIKEN, Yokohama, Japan (Y.S.)
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Tadahaya Mizuno
Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan (K.A., H.H., K.I., T.M.); and Sugiyama Laboratory, RIKEN Innovation Center, Research Cluster for Innovation, RIKEN, Yokohama, Japan (Y.S.)
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Yuichi Sugiyama
Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan (K.A., H.H., K.I., T.M.); and Sugiyama Laboratory, RIKEN Innovation Center, Research Cluster for Innovation, RIKEN, Yokohama, Japan (Y.S.)
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Article Information

vol. 85 no. 3 482-491
DOI 
https://doi.org/10.1124/mol.113.091090
PubMed 
24378332

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0026-895X
Online ISSN 
1521-0111
History 
  • Received December 6, 2013
  • Accepted December 17, 2013
  • Published online January 28, 2014.

Article Versions

  • Earlier version (December 30, 2013 - 06:43).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Kensuke Aida,
  2. Hisamitsu Hayashi,
  3. Kaori Inamura,
  4. Tadahaya Mizuno, and
  5. Yuichi Sugiyama
  1. Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan (K.A., H.H., K.I., T.M.); and Sugiyama Laboratory, RIKEN Innovation Center, Research Cluster for Innovation, RIKEN, Yokohama, Japan (Y.S.)
  1. Address correspondence to:
    Dr. Hisamitsu Hayashi, Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. E-mail: hayapi{at}mol.f.u-tokyo.ac.jp
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Molecular Pharmacology: 85 (3)
Molecular Pharmacology
Vol. 85, Issue 3
1 Mar 2014
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Research ArticleArticle

Intracellular Transport of BSEP and MRP2 via Ubiquitination

Kensuke Aida, Hisamitsu Hayashi, Kaori Inamura, Tadahaya Mizuno and Yuichi Sugiyama
Molecular Pharmacology March 1, 2014, 85 (3) 482-491; DOI: https://doi.org/10.1124/mol.113.091090

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Research ArticleArticle

Intracellular Transport of BSEP and MRP2 via Ubiquitination

Kensuke Aida, Hisamitsu Hayashi, Kaori Inamura, Tadahaya Mizuno and Yuichi Sugiyama
Molecular Pharmacology March 1, 2014, 85 (3) 482-491; DOI: https://doi.org/10.1124/mol.113.091090
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